SECURITIES AND EXCHANGE COMMISSION

                             WASHINGTON, D.C. 20549

                                    FORM 8-K


                                 CURRENT REPORT
                     Pursuant to Section 13 or 15(d) of the
                         Securities Exchange Act of 1934


                Date of Report (Date of earliest event reported):
                                   MAY 3, 2005


                                  GENOMED, INC.
             (Exact name of registrant as specified in its charter)


----------------------------- --- ------------------ --- -----------------------
          FLORIDA                     000-49720                43-1916702
----------------------------- --- ------------------ --- -----------------------
(State or other jurisdiction       (Commission file           (IRS Employer
     of incorporation)                  number)           Identification Number)
----------------------------- --- ------------------ --- -----------------------


             9666 OLIVE BLVD., SUITE 310, ST. LOUIS, MISSOURI 63132
             ------------------------------------------------------
               (Address of principal executive offices) (Zip Code)


               REGISTRANT'S TELEPHONE NUMBER, INCLUDING AREA CODE:
               ---------------------------------------------------
                                 (314) 983-9933




ITEM 4.01 CHANGES IN REGISTRANT'S CERTIFYING ACCOUNTANT

(a)  The registrant's  independent auditor,  Rubin, Brown,  Gornstein & Co., LLP
     ("RBG") declined to stand for reelection,  and,  effective May 3, 2005, RBG
     was dismissed.

     The report of RBG on the financial  statements  for the year ended December
     31, 2004 contained no adverse  opinion or disclaimer of opinion and was not
     qualified  or  modified  as  to  uncertainty,  audit  scope  or  accounting
     principle,  except  that the report for the year ended  December  31,  2004
     contained an explanatory  paragraph expressing doubt about the Registrant's
     ability to continue as a going concern.

     RBG  served  as the  auditor  during  the most  recent  fiscal  year of the
     registrant (2004), and during that time there has been no disagreement with
     RBG  on  any  matter  of  accounting  principles  or  practices,  financial
     statement disclosure, or auditing scope or procedure, which if not resolved
     to the  satisfaction  of RBG, would have caused it to make reference to the
     subject matter of the disagreement in connection with its report.

     The  registrant has authorized RBG to respond fully to any inquiries of its
     new auditor  concerning any issue relating to the  registrant's  accounting
     principles or practices or financial reporting,  the registrant's financial
     statements or RBG's audit thereof or audit opinions thereon.

     The  registrant  has provided a copy of the  disclosures  in this report to
     RBG.  Any letter from RBG pursuant to paragraph  (a)(3) of  Regulation  S-K
     will be supplied by amendment.



SIGNATURE

Pursuant  to the  requirements  of the  Securities  Exchange  Act of  1934,  the
registrant  has duly  caused  this  Report  to be  signed  on its  behalf by the
undersigned hereunto duly authorized.


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                                     GenoMed, Inc.


Dated:  May 6, 2005                  By:   /s/ Dr. David Moskowitz
                                           --------------------------------
                                           Dr. David Moskowitz
                                           Chairman of the Board and
                                           Chief Executive Officer
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