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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, D.C. 20549

FORM 10-Q

Commission file number 001-15943

CHARLES RIVER LABORATORIES
INTERNATIONAL, INC.

(Exact Name of Registrant as specified in its Charter)

251 BALLARDVALE STREET, WILMINGTON, MASSACHUSETTS 01887
(Address of Principal Executive Offices) (Zip Code)

781-222-6000
(Registrant's Telephone Number, Including Area Code)

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        Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ý    No o

        Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Web site, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.402 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files). Yes ý    No o

        Indicate by check mark whether the Registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of "large accelerated filer," "accelerated filer" and "smaller reporting company" in Rule 12b-2 of the Exchange Act. (check one):

        Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes o    No ý

        As of August 1, 2009, there were 65,893,790 shares of the registrant's common stock outstanding.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

FORM 10-Q

For the Quarterly Period Ended June 27, 2009

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Special Note on Factors Affecting Future Results

        This Quarterly Report on Form 10-Q contains forward-looking statements regarding future events and the future results of Charles River Laboratories International, Inc. ("Charles River") that are based on current expectations, estimates, forecasts, and projections about the industries in which Charles River operates and the beliefs and assumptions of our management. Words such as "expect," "anticipate," "target," "goal," "project," "intend," "plan," "believe," "seek," "estimate," "will," "likely," "may," "designed," "would," "future," "can," "could" and other similar expressions that are predictions of or indicate future events and trends or which do not relate to historical matters are intended to identify such forward-looking statements. These statements are based on current expectations and beliefs of Charles River and involve a number of risks, uncertainties, and assumptions that are difficult to predict. For example, we may use forward-looking statements when addressing topics such as: future demand for drug discovery and development products and services, including the outsourcing of these services; present spending trends and other cost reduction activities by our customers (particularly in light of the challenging economic environment); future actions by our management; the outcome of contingencies; changes in our business strategy; changes in our business practices and methods of generating revenue; the development and performance of our services and products; market and industry conditions, including competitive and pricing trends; changes in the composition or level of our revenues; our cost structure; the impact of acquisitions and dispositions; the timing of the opening of new and expanded facilities; our expectations with respect to sales growth, efficiency improvements and operating synergies (including the impact of specific actions intended to cause related improvements); changes in our expectations regarding future stock option, restricted stock, performance awards and other equity grants to employees and directors; changes in our expectations regarding our stock repurchases; expectations with respect to foreign currency exchange; assessing (or changing our assessment of) our tax positions for financial statement purposes; and our cash flow and liquidity. In addition, these statements include the availability of funding for our customers and the impact of economic and market conditions on them generally, the effects of our first half 2009 cost-saving actions and other actions designed to manage expenses, operating costs and capital spending and to streamline efficiency, and the ability of Charles River to withstand the current market conditions. You should not rely on forward-looking statements because they are predictions and are subject to risks, uncertainties and assumptions that are difficult to predict. Therefore, actual results may differ materially and adversely from those expressed in any forward-looking statements. You are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date of this document or in the case of statements incorporated by reference, on the date of the document incorporated by reference. Factors that might cause or contribute to such differences include, but are not limited to, those discussed in our Annual Report on Form 10-K for the year ended December 27, 2008 under the section entitled "Our Strategy" and the section entitled "Risks Related to Our Business and Industry," the section of this Quarterly Report on Form 10-Q entitled "Management's Discussion and Analysis of Financial Condition and Results of Operations" and in our press releases and other financial filings with the Securities and Exchange Commission. We have no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or risks. New information, future events or risks may cause the forward-looking events we discuss in this report not to occur.

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Part I. Financial Information

Item 1.    Financial Statements

        

CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED STATEMENTS OF INCOME (UNAUDITED)

(dollars in thousands, except per share amounts)

See Notes to Condensed Consolidated Interim Financial Statements

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED STATEMENTS OF INCOME (UNAUDITED)

(dollars in thousands, except per share amounts)

See Notes to Condensed Consolidated Interim Financial Statements

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED BALANCE SHEETS (UNAUDITED)

(dollars in thousands, except per share amounts)

See Notes to Condensed Consolidated Interim Financial Statements

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS (UNAUDITED)

(dollars in thousands)

See Notes to Condensed Consolidated Interim Financial Statements

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

CONDENSED CONSOLIDATED STATEMENT OF CHANGES IN
SHAREHOLDERS' EQUITY (UNAUDITED)

(dollars in thousands)

See Notes to Condensed Consolidated Interim Financial Statements

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS

(dollars in thousands, except per share amounts)

1. Basis of Presentation

        The condensed consolidated interim financial statements are unaudited, and certain information and footnote disclosures related thereto normally included in financial statements prepared in accordance with generally accepted accounting principles in the United States of America have been omitted in accordance with Rule 10-01 of Regulation S-X. In the opinion of management, the accompanying unaudited condensed consolidated financial statements were prepared following the same policies and procedures used in the preparation of the audited financial statements and reflect all adjustments (consisting of normal recurring adjustments) considered necessary to state fairly the financial position and results of operations of Charles River Laboratories International, Inc. The results of operations for the interim periods are not necessarily indicative of the results for the entire fiscal year. These condensed consolidated financial statements should be read in conjunction with our Annual Report on Form 10-K for the year ended December 27, 2008.

        Effective December 28, 2008, we adopted FSP No. APB 14-1, "Accounting for Convertible Debt Instruments That May Be Settled in Cash upon Conversion (Including Partial Cash Settlement)" (FSP 14-1). FSP 14-1 requires retrospective application to all periods presented and accordingly, amounts in prior-year financial statements and related notes have been restated (see footnote 8). In addition, on December 28, 2008, we adopted FAS No. 160, Noncontrolling Interests in Consolidated Financial Statements (FAS 160) and as a result; certain amounts in prior-year financial statements and related notes have been reclassified to conform to the current year presentation (see footnote 9).

2. Business Acquisitions

        On May 1, 2009, we acquired the business and assets of Piedmont Research Center (PRC) for $45,775 which is included in our RMS segment. PRC, which is based in North Carolina, provides discovery services focused on efficacy studies in oncology and other therapeutic areas for pharmaceutical and biotechnology clients which will significantly expand the oncology services offered through our discovery and imaging services. The preliminary purchase price allocation is as follows:

        The breakout of goodwill and other intangibles acquired with the acquisition was as follows:

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

2. Business Acquisitions (Continued)

        In April 2009, we acquired certain assets of Medical Supply Company, LTD, an Irish based provider of products and services for the purpose of endotoxin detection, testing and assessment for $5,386. Intangibles of $4,940 were recorded related to customer relationships with a 4.5 year weighted average amortization life.

        For the three and six months ended June 27, 2009, $3,118 of revenue and $67 of operating income are included in our consolidated statements of income related to these acquisitions.

        The following selected unaudited pro forma consolidated results of operations are presented as if each of the acquisitions had occurred as of the beginning of each period presented after giving effect to certain adjustments including the amortization of intangibles. The pro forma data is for informational purposes only and does not necessarily reflect the results of operations had the companies operated as one during the periods reported. No effect has been given for synergies, if any, that may have been realized through the acquisitions.

        Refer to Note 9 for further discussion of the method of computation of earnings per share.

3. 2009 Actions

        During the first and second quarters of 2009 we implemented staffing reductions to improve operating efficiency and profitability at various sites including our Arkansas facility which we plan to close this year. As a result of these actions, we recorded severance charges of $8,812 including $3,423 in cost of sales and $5,389 in selling, general and administrative expense. As of June 27, 2009, $3,553 was included in accrued compensation and $1,816 in other long term liabilities on our consolidated balance sheet. We expect to incur additional severance expense of $889 during the remainder of 2009.

4. Supplemental Balance Sheet Information

        The composition of trade receivables is as follows:

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

4. Supplemental Balance Sheet Information (Continued)

        The composition of inventories is as follows:

        The composition of other current assets is as follows:

        The composition of net property, plant and equipment is as follows:

        Depreciation expense for the six months ended June 27, 2009 and June 28, 2008 was $31,503 and $30,212, respectively.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

4. Supplemental Balance Sheet Information (Continued)

        The composition of other assets is as follows:

        The composition of other current liabilities is as follows:

        The composition of other long-term liabilities is as follows:

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

5. Marketable Securities

        The cost, gross unrealized gains, gross unrealized losses and fair value for marketable securities by major security type were as follows:

 

        As of June 27, 2009, we held $19,353 in auction rate securities which are variable rate debt instruments, which bear interest rates that reset approximately every 7 or 35 days. The auction rate securities owned were rated AAA by a major credit rating agency and are guaranteed by the Federal Family Education Loan Program (FFELP). The auction rate securities have contractual maturities which are greater than 25 years. The auction rate securities are classified as available-for-sale and are recorded at fair value. We have classified these investments as long-term consistent with the term of the underlying security which are structured with short-term interest rate reset dates but with contractual maturities that are long-term.

        Effective March 29, 2009, we adopted FSP FAS 115-2 and FAS 124-2, Recognition and Presentation of Other-Than-Temporary Impairments. This FSP establishes a new method of recognizing and reporting other-than-temporary impairment guidance on debt securities. Accordingly, we recorded a $47 impairment loss in earnings for the quarter ended June 27, 2009.

        Maturities of investments are as follows:

        Marketable securities due after one year are included in other assets on the consolidated balance sheets.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

6. Fair Value

        We hold cash equivalents, investments and certain other assets that are carried at fair value. We generally determine fair value using a market approach based on quoted prices of identical instruments when available. When market quotes of identical instruments are not readily accessible or available, we determine fair value based on quoted market prices of similar instruments. Disclosure for assets and liabilities that are measured at fair value but recognized and disclosed at fair value on a nonrecurring basis are required prospectively beginning January 1, 2009. As of June 27, 2009, we do not have any significant non-recurring measurements of nonfinancial assets and nonfinancial liabilities.

        FAS No. 157, Fair Value Measurements (FAS 157), establishes a valuation hierarchy for disclosure of the inputs to the valuations used to measure fair value. This hierarchy prioritizes the inputs into three broad levels as follows. Level 1 inputs are quoted prices (unadjusted) in active markets for identical assets or liabilities. Level 2 inputs are quoted prices for similar assets and liabilities in active markets, quoted prices for identical or similar assets in markets that are not active, inputs other than quoted prices that are observable for the asset or liability, including interest rates, yield curves and credit risks, or inputs that are derived principally from or corroborated by observable market data through correlation. Level 3 inputs are unobservable inputs based on our own assumptions used to measure assets and liabilities at fair value. A financial asset or liability's classification within the hierarchy is determined based on the lowest level input that is significant to the fair value measurement.

        Assets measured at fair value on a recurring basis are summarized below:

 

        The table below presents a reconciliation for all assets measured at fair value on a recurring basis using significant unobservable inputs (Level 3) during the quarters ended June 27, 2009 and June 28,

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

6. Fair Value (Continued)

2008. Our auction rate securities were valued at fair value by management in part utilizing an independent valuation reviewed by management which used pricing models and discounted cash flow methodologies incorporating assumptions that reflect the assumptions a marketplace participant would use at June 27, 2009.

7. Goodwill and Other Intangible Assets

        The following table displays goodwill and other intangible assets not subject to amortization and other intangible assets that continue to be subject to amortization:

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

7. Goodwill and Other Intangible Assets

        The changes in the gross carrying amount and accumulated amortization of goodwill are as follows:

8. Long-Term Debt

Long-Term Debt

        Long-term debt consists of the following:

        The interest rates applicable to term loans and revolving loans under the credit agreement are, at our option, equal to either the base rate (which is the higher of the prime rate or the federal funds rate plus 0.50%) or the adjusted LIBOR rate plus an interest rate margin based upon our leverage ratio. Based on our leverage ratio, the margin range for LIBOR-based loans is 0.625% to 0.875%. As of June 27, 2009, the interest rate margin was 0.625%.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

8. Long-Term Debt (Continued)

        We pledged the stock of certain subsidiaries as well as certain U.S. assets for our credit agreements. In addition, credit agreements include certain customary representations and warranties, events of default, notice of material adverse change to our business and negative and affirmative covenants including the ratio of consolidated earnings before interest, taxes, depreciation and amortization to consolidated interest expense, for any period of four consecutive fiscal quarters, of no less than 3.5 to 1.0 as well as the ratio of consolidated indebtedness to consolidated earnings before interest, taxes, depreciation and amortization for any period of four consecutive fiscal quarters, of no more than 3.0 to 1.0. As of June 27, 2009 we were compliant with all financial covenants specified in the credit agreement. We had $5,627 outstanding under letters of credit as of June 27, 2009.

        Our $350,000 of 2.25% Convertible Senior Notes (the 2013 Notes) due in June, 2013 with interest payable semi-annually. The 2013 Notes are convertible into cash for the principal amount and shares of our common stock for the conversion premium (or, at our election, cash in lieu of some or all of such common stock), if any, based on an initial conversion rate, subject to adjustment, of 20.4337 shares of our common stock per $1,000 principal amount of notes (which represents an initial conversion price of $48.94 per share), only in the following circumstances and to the following extent: (1) during any fiscal quarter beginning after July 1, 2006 (and only during such fiscal quarter), if the last reported sale price of our common stock for at least 20 trading days in the period of 30 consecutive trading days ending on the last trading day of the immediately preceding fiscal quarter is more than 130% of the conversion price on the last day of such preceding fiscal quarter; (2) during the five business-day period after any five consecutive trading-day period, or the measurement period, in which the trading price per note for each day of that measurement period was less than 98% of the product of the last reported sale price of our common stock and the conversion rate on each such day; (3) upon the occurrence of specified corporate transactions, as described in the indenture for the 2013 Notes; and (4) at the option of the holder at any time beginning on the date that is two months prior to the stated maturity date and ending on the close of business on the second trading-day immediately preceding the maturity date. Upon conversion, we will pay cash and shares of our common stock (or, at our election, cash in lieu of some or all of such common stock), if any. If we undergo a fundamental change as described in the indenture for the 2013 Notes, holders will have the option to require us to purchase all or any portion of their notes for cash at a price equal to 100% of the principal amount of the notes to be purchased plus any accrued and unpaid interest, including any additional interest to, but excluding, the purchase date. If the 2013 Notes were converted on June 27, 2009, they would have a value less than their principal amount.

        At June 27, 2009, the fair value of our outstanding convertible senior notes was approximately $316,745 based on their quoted market value and no conversion triggers were met.

        Effective December 28, 2008, we adopted FSP 14-1. This FSP specifies that issuers of convertible debt instruments that may be settled in cash upon conversion should separately account for the liability and equity components in a manner that reflects the entity's nonconvertible debt borrowing rate when interest cost is recognized in subsequent periods. Upon adoption of the provisions of FSP 14-1, $261,508 of the total proceeds from our $350,000 convertible debt was allocated to the liability component, which represents the estimated fair value of similar debt instruments without the conversion option as of June 12, 2006, the date of issuance. The remaining $88,492 was allocated to the

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

8. Long-Term Debt (Continued)

equity component. The debt discount of $88,492 will be amortized to interest expense over the seven-year period from June 2006 to June 2013, the expected life of the instrument. In addition, $8,463 of capitalized interest expense was recorded retrospectively and will amortize over a weighted average life of 32 years. Additionally, upon adoption, approximately $1,903 of deferred financing costs capitalized at the time of issuance was reclassified to equity as equity issuance costs and will not be amortized to interest expense. As a result of the establishment of the debt discount as of the date of issuance, the non-current deferred tax asset relating to the original issue discount has been reduced by $36,437 as of the date of issuance by offsetting additional paid in capital.

        As of June 27, 2009, $54,861 of debt discount remained and will be amortized over 16 quarters. As of June 27, 2009 and December 27, 2008, the equity component of our convertible debt was $88,492. In accordance with FSP 14-1 interest expense related to our convertible debt of $2,976 and $2,783 was recognized for the three months ended June 27, 2009 and June 28, 2008, respectively, and for the for the six months ended June 27, 2009 and June 28, 2008, $5,906 and $5,523, respectively, yielding an effective interest rate of 6.93% on the liability component. In addition, $1,969 and $3,937 of contractual interest expense was recognized on our convertible debt during the three and six months ended June 27, 2009 and $1,969 and $3,916 of contractual interest expense was recognized on our convertible debt during the three and six months ended June 28, 2008, respectively. Capitalized interest of $271 and $776, respectively, was recorded in accordance with FSP 14-1 during the quarters ended June 27, 2009 and June 28, 2008.

        The condensed consolidated income statement was retroactively modified compared to previously reported amounts as follows:

        Principal maturities of existing debt which excludes unamortized debt discount for the periods set forth in the table below are as follows:

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

9. Equity

Earnings per Share

        Basic earnings per share for the three and six months ended June 27, 2009 and June 28, 2008 were computed by dividing earnings available to common shareowners for these periods by the weighted average number of common shares outstanding in the respective periods adjusted for contingently issuable shares. The weighted average number of common shares outstanding for the three and six months ended June 27, 2009 and June 28, 2008 has been adjusted to include common stock equivalents for the purpose of calculating diluted earnings per share for these periods.

        Options to purchase 6,332,469 and 824,421 shares were outstanding in each of the three respective months ended June 27, 2009 and June 28, 2008, but were not included in computing diluted earnings per share because their inclusion would have been anti-dilutive. Options to purchase 4,388,779 and 941,242 shares were outstanding in each of the respective six months ended June 27, 2009 and June 28, 2008, but were not included in computing diluted earnings per share because their inclusion would have been anti-dilutive.

        Basic weighted average shares outstanding for the three and six months ended June 27, 2009 and June 28, 2008 excluded the weighted average impact of 1,033,119 and 839,151 shares, respectively, of non-vested fixed restricted stock awards.

        The following table illustrates the reconciliation of the numerator and denominator of the basic and diluted earnings per share computations for income from continuing operations and income (loss) from operations of discontinued businesses:

        The sum of our quarterly earnings per share does not necessarily equal our earnings per share for the six months ended June 27, 2009 and June 28, 2008 due to rounding.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

9. Equity (Continued)

Treasury Shares

        The Board of Directors has authorized a share repurchase program, originally authorized on July 27, 2005 and subsequently amended on October 26, 2005, May 9, 2006, August 1, 2007 and July 24, 2008 to acquire up to a total of $600,000 of common stock. The program does not have a fixed expiration date. In order to facilitate these share repurchases, we entered into Rule 10b5-1 Purchase Plans. As of June 27, 2009, approximately $144,753 remains authorized for share repurchases.

        Share repurchases during the three and six months ended June 27, 2009 and June 28, 2008 were as follows:

        Additionally, the Company's 2000 Incentive Plan and 2007 Incentive Plan permits the netting of common stock upon vesting of restricted stock awards in order to satisfy individual tax withholding requirements. During the six months ended June 27, 2009 and June 28, 2008, we acquired 58,282 shares for $1,483 and 80,534 shares for $4,726, respectively, as a result of such withholdings. During the three months ended June 27, 2009 and June 28, 2008, we acquired 2,794 shares for $78 and 4,416 shares for $270, respectively.

        The timing and amount of any future repurchases will depend on market conditions and corporate considerations.

Warrants

        Separately and concurrently with the pricing of the 2013 Notes, we issued warrants for approximately 7.2 million shares of our common stock. The warrants give the holders the right to receive, for no additional consideration, cash or shares (at our option) with a value equal to the appreciation in the price of our shares above $59.925, and expire between September 13, 2013 and January 22, 2014 over 90 equal increments. The total proceeds from the issuance of the warrants were $65,423.

        As part of our recapitalization in 1999, we issued 150,000 units, each comprised of a $1,000 senior subordinated note and a warrant to purchase 7.6 shares of our common stock for total proceeds of $150,000. We allocated the $150,000 offering proceeds between the senior subordinated notes ($147,872) and the warrants ($2,128), based upon the estimated fair value. The portion of the proceeds allocated to the warrants is reflected as capital in excess of par in the accompanying consolidated financial statements. Each warrant entitles the holder, subject to certain conditions, to purchase 7.6 shares of our common stock at an exercise price of $5.19 per share of common stock, subject to adjustment under some circumstances. Upon exercise, the holders of warrants would be entitled to purchase 1,140 shares of our common stock as of June 27, 2009. The warrants expire on October 1, 2009.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

9. Equity (Continued)

        A summary of the changes in equity for the six months ended June 27, 2009 and June 28, 2008 is provided below:

        Effective December 28, 2008, we adopted the provisions of FAS 160. Certain provisions of this statement are required to be adopted retrospectively for all periods presented. Such provisions include a requirement that the carrying value of noncontrolling interests (previously referred to as minority interests) be removed from the mezzanine section of the balance sheet and reclassified as equity; and consolidated net income to be recast to include net income (loss) attributable to the noncontrolling interest. As a result of this adoption, we reclassified noncontrolling interests in the amounts of

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

9. Equity (Continued)

$(613) and $422 from the mezzanine section to equity in the June 27, 2009 and December 28, 2008 balance sheets, respectively.

10. Income Taxes

        The following table provides a reconciliation of the provision for income taxes on the condensed consolidated statements of income:

        Our overall effective tax rate was 28.8% in the second quarter of 2009 and 25.9% in the second quarter of 2008. The increase from the 25.9% effective tax rate in the second quarter of 2008 is primarily attributable to declines in Canadian investment tax credits and unbenefitted start-up losses incurred in the second quarter of 2009 related to the Company's PCS facility in China.

        During the second quarter of 2009, our unrecognized tax benefits recorded in accordance with FASB Interpretation No. 48, Accounting for Uncertainty in Income Taxes, increased by $1,545 to $30,038 primarily due to foreign exchange movement and ongoing evaluation of uncertain tax positions in the current and prior period. The amount of unrecognized tax benefits that would impact the effective tax rate favorably if recognized increased by $1,191 to $22,295 during the second quarter of 2009.

        We conduct business in a number of tax jurisdictions. As a result, we are subject to tax audits on a regular basis including, but not limited to, such major jurisdictions as the United States, the United Kingdom, Germany and Canada. With few exceptions, we are no longer subject to U.S. and international income tax examinations for years before 2003.

        We and certain of our subsidiaries are currently under audit by the Canada Revenue Agency (CRA), the German Tax Office, the Internal Revenue Service (IRS) in the United States, and the Commonwealth of Massachusetts.

        During the second quarter of 2009, we received Notices of Reassessment from the CRA with respect to tax credits claimed in 2003 and 2004 by our Canadian PCS subsidiary. We disagree with the positions taken by the CRA and intend to contest them by filing formal Notices of Objection with the agency. We do not believe that resolution of the reassessments with CRA will have a material impact on our financial position or results of operations. It is possible that CRA will propose similar adjustments for later years.

        It is reasonably possible that the Company will settle with the IRS Appeals division on proposed adjustments related to the 2004 and 2005 tax filings for the Company and an acquired subsidiary and conclude an IRS examination of the 2006 tax filings for the Company within the next twelve months. We do not anticipate that the settlement of the proposed audit adjustments, which relate primarily to

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

10. Income Taxes (Continued)

issues associated with an acquisition, will have a material impact on our financial position or results of operations. We believe that we have appropriately provided for all uncertain tax positions.

11. Employee Benefits

        The following table provides the components of net periodic benefit cost for our defined benefit plans:

Pension Benefits

Supplemental Retirement Benefits

        We expect to contribute $16,688 to these plans during 2009.

12. Stock-Based Compensation Plans

        We grant stock options and restricted stock to employees and non-employee directors under our share-based compensation plans. Stock-based compensation cost is measured at grant date, based on the fair value of the award and is recognized as expense on a straight-line basis over the requisite

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

12. Stock-Based Compensation Plans (Continued)

service period. The effect of recording stock-based compensation for the three and six months ended June 27, 2009 and June 28, 2008 was as follows:

        We estimate the fair value of stock options using the Black-Scholes valuation model. Key inputs and assumptions used to estimate the fair value of stock options include the exercise price of the award, the expected option term, the risk-free interest rate over the option's expected term, the expected annual dividend yield and the expected stock price volatility. The expected stock price volatility assumption was determined using the historical volatility of our common stock over the expected life of the option. The risk-free interest rate was based on the market yield for the five year U.S. Treasury security. The expected life of options was determined using historical option exercise activity. Management believes that the valuation technique and the approach utilized to develop the underlying assumptions are appropriate in calculating the fair values of our stock options granted. Estimates of fair value are not intended to predict actual future events or the value ultimately realized by persons who receive equity awards.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

12. Stock-Based Compensation Plans (Continued)

        The fair values of stock option awards granted were estimated on the grant date using the Black-Scholes option-pricing model with the following weighted-average assumptions:

Stock Options

        The following table summarizes the stock option activity in the equity incentive plans from December 27, 2008 through June 27, 2009:

        As of June 27, 2009, the unrecognized compensation cost related to unvested stock options was $27,079 net of estimated forfeitures. This unrecognized compensation will be recognized over an estimated weighted-average amortization period of 33 months.

        The total fair value of the options vested during the three and six months ended June 27, 2009 was $1,215 and $7,226, respectively. The total fair value of the options vested during the three and six months ended June 28, 2008 was $1,434 and $9,415, respectively.

        The total intrinsic value of options exercised during the three and six months ended June 27, 2009 was $68 and $61, respectively. The total intrinsic value of options exercised during the three and six months ended June 28, 2008 was $4,047 and $10,323, respectively. Intrinsic value is defined as the difference between the market price on the date of exercise and the grant date price.

        The total amount of cash received from the exercise of options during the six months ended June 27, 2009 and June 28, 2008 was $47 and $16,512, respectively. The actual tax benefit realized for the tax deductions from option exercises totaled $17 and $3,689 for the six months ended June 27, 2009 and June 28, 2008, respectively.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

12. Stock-Based Compensation Plans (Continued)

        We settle employee stock option exercises with newly issued common shares.

Restricted Stock

        Stock compensation expense associated with restricted common stock is charged for the market value on the date of grant, less estimated forfeitures, and is amortized over the awards' vesting period on a straight-line basis.

        The following table summarizes the restricted stock activity from December 27, 2008 through June 27, 2009:

        As of June 27, 2009, the unrecognized compensation cost related to unvested restricted stock was $30,272 net of estimated forfeitures. This unrecognized compensation will be recognized over an estimated weighted average amortization period of 31 months.

        The total fair value of restricted stock grants that vested during the three and six months ended June 27, 2009 was $1,523 and $10,515, respectively. The total fair value of restricted stock grants that vested during the three and six months ended June 28, 2008 was $1,420 and $12,826, respectively.

Performance-Based Stock Award Program

        During the three and six months ending June 27, 2009 and June 28, 2008, compensation expense of $106 and $856; $201 and $1,538, respectively, was recorded associated with performance based stock awards.

13. Commitments and Contingencies

        Various lawsuits, claims and proceedings of a nature considered normal to its business are pending against us. In the opinion of management, the outcome of such proceedings and litigation currently pending will not materially affect our consolidated financial statements. In addition, we have certain purchase commitments related to the completion of ongoing capacity expansion which amounted to approximately $5,091 as of June 27, 2009.

14. Business Segment Information

        We report two segments, Research Models and Services (RMS) and Preclinical Services (PCS).

        Our RMS segment includes sales of research models, genetically engineered models and services, research animal diagnostics, discovery services, consulting and staffing services, vaccine support and

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

14. Business Segment Information (Continued)

endotoxin and microbial detection. Our PCS segment includes services required to take a drug through the development process including discovery support, toxicology, pathology, biopharmaceutical, bioanalysis, pharmacokinetics and drug metabolism services as well as Phase I clinical trials.

        The following table presents sales to unaffiliated customers and other financial information by product line segment:

        A reconciliation of segment operating income to consolidated operating income is as follows:

        A summary of unallocated corporate overhead consists of the following:

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

14. Business Segment Information (Continued)

        Other general unallocated corporate expenses consist of various departmental costs including those associated with departments such as senior executives, corporate accounting, legal, tax, human resources, treasury and investor relations.

15. Recently Issued Accounting Standards

        Effective December 28, 2008, we adopted FSP No. EITF 03-6-1, "Determining Whether Instruments Granted in Share-Based Payment Transactions Are Participating Securities" (FSP EITF 03-6-1) which clarifies that share-based payment awards that entitle their holders to receive nonforfeitable dividends before vesting should be considered participating securities. As participating securities, these instruments should be included in the calculation of basic earnings per share. The adoption of FSP EITF 03-6-1 had no impact on our consolidated financial statements.

        Effective December 28, 2008, we adopted FAS No. 161, Disclosures about Derivative Instruments and Hedging Activities (FAS 161). FAS 161 changes the disclosure requirements for derivative instruments and hedging activities. Entities are required to provide enhanced disclosures about (a) how and why an entity uses derivative instruments, (b) how derivative instruments and related hedged items are accounted for under Statement 133 and its related interpretations, and (c) how derivative instruments and related hedged items affect an entity's financial position, financial performance and cash flows. The adoption of this statement did not have an impact on our consolidated financial statements.

        Effective December 28, 2008, we adopted FSP FAS 140-3: "Accounting for Transfers of Financial Assets and Repurchase Financing Transactions" (FSP 140-3). FSP 140-3 provides guidance on accounting for a transfer of a financial asset and a repurchase financing. This FSP presumes that an initial transfer for a financial asset and a repurchase financing are considered part of the same arrangement (linked transaction) under Statement 140. However, if certain criteria are met, the initial transfer and repurchase financing shall not be evaluated as a linked transaction and shall be evaluated separately under Statement 140. This FSP did not have an impact on our consolidated financial statements.

        Effective December 28, 2008, we adopted FAS No. 141(R), Business Combinations (FAS 141(R)) and No. 160, Noncontrolling Interests in Consolidated Financial Statements (FAS 160). FAS 141(R) and FAS 160 introduce significant changes in the accounting for and reporting of business acquisitions and noncontrolling interests, formerly "minority interest," in a subsidiary. FAS 141(R) continues the movement toward the greater use of fair values in financial reporting and increased transparency through expanded disclosures. FAS 141(R) changes how business acquisitions are accounted for and will impact the annual goodwill impairment test associated with acquisitions that close both before and after its effective date. FAS 141(R) amends FAS 109 changing the accounting for adjustments to deferred tax asset valuation allowances and income tax uncertainties related to acquisitions that close both before and after its effective date, generally requiring adjustments to be reflected in income tax expense. The adoption of FAS 141(R) and FAS 160 has not materially impacted our consolidated financial statements to date.

        Effective March 29, 2009, we adopted FSP FAS 157-4, "Determining Fair Value When the Volume and Level Activity for the Asset of Liability Have Significantly Decreased and Identifying Transactions That Are Not Orderly." This FSP provides additional guidance for estimating fair value in accordance

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

15. Recently Issued Accounting Standards (Continued)

with FAS 157, Fair Value Measurements, when the volume and level of activity for the asset or liability have significantly decreased. This FSP also includes guidance on identifying circumstances that indicate a transaction is not orderly. This FSP emphasizes that even if there has been a significant decrease in the volume and level of activity for the asset or liability and regardless of the valuation technique(s) used, the objective of a fair value measurement remains the same. Fair value is the price that would be received to sell an asset or paid to transfer a liability in an orderly transaction (that is, not a forced liquidation or distressed sale) between market participants at the measurement date under current market conditions. The adoption of this FSP did not have an impact on our consolidated financial statements.

        Effective March 29, 2009, we adopted FSP FAS 115-2 and FAS 124-2, "Recognition and Presentation of Other-Than-Temporary Impairments." This FSP amends the other-than-temporary impairment guidance in U.S.GAAP for debt securities to make the guidance more operational and to improve the presentation and disclosure of other-than-temporary impairments on debt and equity securities in the financial statements. This FSP does not amend existing recognition and measurement guidance related to other-than-temporary impairments of equity securities. The adoption of this FSP did not have a material impact on our consolidated financial statements.

        Effective March 29, 2009, we adopted FSP FAS 107-1 and APB 28-1, "Interim Disclosures about Fair Value of Financial Instruments," to require disclosures about fair value of financial instruments for interim reporting periods of publicly traded companies as well as in annual financial statements. This FSP also amends APB 28, "Interim Financial Reporting," to require those disclosures in summarized financial information at interim reporting periods. The adoption of this FSP did not have an impact on our consolidated financial statements.

        In December 2008, the FASB issued FSP FAS 132 (R)-1, "Employers' Disclosures about Postretirement Benefit Plan Assets." This FSP amends FAS 132, Employers' Disclosures about Pensions and Other Postretirement Benefits, to provide guidance on an employer's disclosures about plan assets of defined benefit pension or other postretirement plan. The disclosures required by this FSP shall be provided for fiscal years ending after December 15, 2009. Upon initial application, the provisions of this FSP are not required for earlier periods that are presented for comparative purposes. The adoption of this FSP will not have an impact on our consolidated financial statements.

        In June 2009, the FASB issued FAS 168, The FASB Accounting Standards Codification™ and the Hierarchy of Generally Accepted Accounting Principles—a replacement of FASB Statement No. 162 which is effective for financial statements issued for interim and annual periods ending after September 15, 2009. The adoption of this pronouncement will not have an impact on our consolidated financial statements.

        In June 2009, the FASB issued FAS 167, Amendments to FASB Interpretation No. 46(R) effective for fiscal years starting after November 15, 2009, or January 1, 2010 for companies reporting earnings on a calendar-year basis. This statement amends certain requirements of FASB Interpretation No. 46 Consolidation of Variable Interest Entities, to improve financial reporting and to provide more relevant and reliable information to users of financial statements. The adoption of this standard is not expected to have an impact on our consolidated financial statements.

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CHARLES RIVER LABORATORIES INTERNATIONAL, INC.

NOTES TO UNAUDITED CONDENSED CONSOLIDATED INTERIM FINANCIAL STATEMENTS (Continued)

(dollars in thousands, except per share amounts)

15. Recently Issued Accounting Standards (Continued)

        In June 2009, the FASB issued FAS 166, Accounting for Transfers of Financial Assets—an amendment of FASB Statement No. 140 effective for fiscal years beginning after November 15, 2009, or January 1, 2010 for companies reporting earnings on a calendar-year basis. The objective of this statement is to improve the information an entity provides in its financial statements about a transfer of financial assets; the effects of a transfer on its financial position, financial performance, and cash flows; and a transferor's continuing involvement in transferred financial assets. The adoption of this pronouncement is not expected to have an impact on our consolidated financial statements.

16. Subsequent Events

        On July 31, 2009, we purchased Finland based Cerebricon Ltd. for approximately $9,000 in cash. Cerebricon Ltd. provides discovery services for therapeutic products for treatment of diseases of the central nervous system (CNS), supported by in vivo imaging capabilities. Cerebricon will join Charles River Discovery and Imaging Services (DIS), a business which has been strategically expanded through the acquisition of MIR and Piedmont Research Center.

        In addition on July 31, 2009, we entered into an agreement to acquire Systems Pathology Company, LLC (SPC), a pathology-based software company developing the Computer Assisted Pathology System (CAPS™), which is expected to be the next generation of automated digital imaging software tools to augment traditional toxicologic pathology practices. SPC is focused on developing state-of-the-art imaging technologies to automate the labor-intensive tissue evaluation process, which is a significant component of standard preclinical studies. The strategic benefits of the CAPS™ platform are to enhance the automation, accuracy, consistency and throughput of traditional toxicologic pathology workflow. SPC will be acquired for an initial payment of approximately $24,000, with future contingent payments based on the achievement of certain undisclosed milestones. The transaction is expected to close during the third quarter of 2009, subject to customary closing conditions.

        In accordance with FAS 165, Subsequent Events, issued in May 2009 by the FASB, we have evaluated subsequent events through the date these financial statements were issued, August 5, 2009. FAS 165 establishes general standards of accounting for and disclosure of events that occur after the balance sheet date but before financial statements are issued or are available to be issued.

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Item 2.    Management's Discussion and Analysis of Financial Condition and Results of Operations

        The following discussion should be read in conjunction with our condensed consolidated financial statements and the related notes.

Overview

        We are a leading global provider of solutions that advance the drug discovery and development process, including research models and associated services and outsourced preclinical services. We provide our products and services to global pharmaceutical companies, biotechnology companies, as well as government agencies, leading hospitals and academic institutions throughout the world in order to bring drugs to market faster and more efficiently. Our broad portfolio of products and services enables our customers to reduce costs, increase speed to market and enhance their productivity and effectiveness in drug discovery and development. We have built upon our core competency of laboratory animal medicine and science (research model technologies) to develop a diverse and growing portfolio of regulatory compliant preclinical services which address drug discovery and development in the preclinical arena. We have been in business for over 60 years and currently operate approximately 70 facilities in 17 countries worldwide.

        Our sales this year have been impacted by continued measured spending by major pharmaceuticals and biotechnology companies due to the impact of the slower economy and world wide credit crisis on our customers, as well as significant impending patent expirations. We believe the reduced demand, which was evident starting in the middle of 2008, has been primarily due to factors which include: business restructuring and reprioritization of pipelines by pharmaceutical and biotechnology clients, which led to significant study slippage and delays in customer decisions and commitments; lack of funding for biotechnology companies; tight cost controls which resulted in more measured spending and pricing pressure; and a focus on late-stage (human) testing as customers endeavor to bring drugs to market. In addition, pharmaceutical and biotechnology companies appear to be entering a period of accelerating consolidation, which is resulting in demand uncertainty. We expect these factors to persist throughout 2009, but we believe that the long-term drivers for our business as a whole will primarily emerge from our customers' continued demand for research models and services and regulatory compliant preclinical services, which are essential to the drug development process.

        Our expectations for the remainder of 2009 reflect ongoing soft market demand, particularly for preclinical services. As our customers reinvigorate their drug development efforts and continue to employ methods to improve the effectiveness and cost efficiency of their drug development pipelines, we believe they will increase their focus on strategic outsourcing, which will drive demand for the services we provide.

        We are using this period of market uncertainty to streamline our operations, and have implemented actions to improve our operating efficiency. The actions we implemented in 2009 include initiating restrictions on hiring, a salary freeze for a substantial percentage of our workforce, including all incentive-eligible employees, continued tight control of discretionary spending and implementing a headcount reduction, predominately in our Preclinical Services (PCS) business segment, reduction in targeted bonus amounts and other benefits, and the planned closure of our Arkansas facility. As a result of these actions, we recorded a charge for severance costs of $8.8 million during 2009. We expect that these actions will reduce costs by approximately $25 million in 2009, with an annual run-rate of approximately $30 million. We divested our clinical Phase I operation in Scotland in the second quarter.

        Our capital expenditures totaled $20.4 million in the second quarter of 2009, compared to $65.0 million in the second quarter of 2008. We have evaluated our expansion plans, taking into consideration the factors that are affecting our sales growth and determined that we have sufficient capacity to accommodate our clients' current demand. We opened the Sherbrooke (Canada) facility in

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the second quarter of 2009, in order to relieve capacity constraints at our Montreal facility. In addition to internally generated organic growth, our business strategy includes strategic "bolt-on" acquisitions that complement our business, increase the rate of our growth or geographically expand our existing services, as evidenced by our acquisition of Piedmont Research Center in the second quarter of 2009.

        Total net sales during the second quarter of 2009 were $308.2 million, a decrease of 12.5% over the same period last year. The sales decrease was due to slower demand for PCS and Research Models and Services (RMS), due to reduced biopharmaceutical spending. The effect of foreign currency translation had a negative impact of 5.1% on sales growth. Our gross margin percentage was 37.1% during the second quarter, compared to 39.2% over the same period last year. This decrease was due mainly to the impact of our lower sales. Our operating income for the second quarter of 2009 was $50.7 million compared to $69.3 million for the second quarter of 2008, a decrease of 26.9%. The operating margin was 16.4% for the second quarter of 2009 compared to 19.7% for the prior year.

        Our net income attributable to common shareholders was $34.2 million for the three months ended June 27, 2009, compared to $49.1 million for the three months ended June 28, 2008. Diluted earnings per share for the second quarter of 2009 were $0.52, compared to $0.70 for the second quarter of 2008.

        Total net sales during the six months ended June 27, 2009 were $609.7 million, a decrease of 11.6% over the same period last year. The sales decrease was due primarily to slower demand for PCS and RMS. The effect of foreign currency translation had a negative impact on sales growth of 5.2%. Our gross margin decreased to 36.5% of net sales for the six months ended June 27, 2009, compared to 38.9% of net sales for the first six months of 2008, due primarily to the impact of our lower sales and severance costs.

        Our operating income for the six months ended June 27, 2009 was $90.6 million compared to $132.8 million for the six months ended June 28, 2008, a decrease of 31.8%. Our operating margin was 14.9% for the six months ended June 27, 2009 compared to 19.3% for the prior year. Net income attributable to common shareholders was $59.6 million for the six months ended June 27, 2009 compared to $93.2 million for the six months ended June 28, 2008. Diluted earnings per share from continuing operations for the first six months of 2009 were $0.91 compared to $1.32 for the first six months of 2008.

        We report two segments: RMS and PCS, which reflect the manner in which our operating units are managed.

        Our RMS segment, which represented 53.8% of net sales in the second quarter of 2009, includes sales of research models, genetically engineered models and services (GEMS), research animal diagnostics, discovery and imaging services, consulting and staffing services, vaccine support, and endotoxin and microbiological detection (formerly referred to as our In Vitro business unit). Net sales for this segment decreased 4.1% compared to the second quarter of 2008, due to unfavorable foreign currency translation of 4.6%. Although the Consulting & Staffing Services business reported lower sales and we divested our Vaccine business in Mexico in 2008, these decreases were offset by the addition of Piedmont Research Center and MIR Preclinical Services. Gross margin decreased to 43.0% from 44.2% due primarily to the impact of our fixed costs with the lower sales. Operating margin increased to 30.7% from 30.2% due primarily to lower operating expenses in Japan.

        Sales on a year to date basis for our RMS business segment decreased 4.2% compared to the first six months of 2008. Operating income on a year to date basis was $98.3 million compared to $108.0 million, a decrease of $9.7 million, or 9.0%, from the same period last year. Operating income for the first six months as a percent of net sales decreased to 30.1% compared to 31.6% for the same period last year.

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        Our PCS segment, which represented 46.2% of net sales in the second quarter of 2009, includes services required to take a drug through the development process including discovery support, toxicology, pathology, biopharmaceutical, bioanalysis, pharmacokinetics and drug metabolism services as well as Phase I clinical trials. Sales for this segment for the second quarter of 2009 decreased 20.5% over the second quarter of 2008. The sales decrease was driven by reduced biopharmaceutical spending, partially offset by the addition of NewLab BioQuality AG, which we acquired in September of 2008. Unfavorable foreign currency decreased sales growth by 5.6%. We experienced decreases in both the PCS gross margin and operating margin (to 30.4% from 34.3% and to 11.5% from 16.1%, respectively), mainly as a result of lower capacity utilization due to the lower sales volume, increased pricing pressure, and costs associated with the start up of our new facilities in China and Canada.

        Sales on a year to date basis for our PCS segment decreased 18.9% over the same period last year. Operating income for the first six months decreased to 9.5% of net sales, compared to 15.0% for the first six months of 2008, due mainly to decreased gross margin.

        Our unallocated corporate headquarters cost increased to $16.5 million in the second quarter of 2009, from $11.7 million in the second quarter of 2008 due mainly to increased health care costs and a pension curtailment gain in 2008.

Three Months Ended June 27, 2009 Compared to Three Months Ended June 28, 2008

        Net Sales.    Net sales for the three months ended June 27, 2009 were $308.2 million, a decrease of $43.9 million, or 12.5%, from $352.1 million for the three months ended June 28, 2008.

        Research Models and Services.    For the three months ended June 27, 2009, net sales for our RMS segment declined to $165.7 million from $172.8 million for the three months ended June 28, 2008, a decrease of 4.1%. RMS sales declined due to unfavorable foreign currency translation, which decreased sales growth by approximately 4.6%, and reduced consulting and staffing services partially offset by the acquisitions of Piedmont Research Center and MIR Preclinical Services.

        Preclinical Services.    For the three months ended June 27, 2009, net sales for our PCS segment were $142.5 million, a decrease of $36.8 million, or 20.5%, compared to $179.3 million for the three months ended June 28, 2008. The decrease was primarily due to reduced biopharmaceutical spending and unfavorable foreign currency translation, which decreased sales growth by 5.6%, partially offset by the addition of NewLab BioQuality AG, which we acquired in September 2008.

        Cost of Products Sold and Services Provided.    Cost of products sold and services provided for the three months ended June 27, 2009 was $193.7 million, a decrease of $20.4 million, or 9.5%, from $214.1 million for the three months ended June 28, 2008. Cost of products sold and services provided for the three months ended June 27, 2009 was 62.9% of net sales, compared to 60.8% for the three months ended June 28, 2008.

        Research Models and Services.    Cost of products sold and services provided for RMS for the three months ended June 27, 2009 was $94.5 million, a decrease of $1.9 million, or 2.0%, compared to $96.4 million for the three months ended June 28, 2008. Cost of products sold and services provided increased as a percentage of net sales to 57.0% for the three months ended June 27, 2009, compared to the three months ended June 28, 2008 at 55.8% of net sales. The increase in cost as a percent of sales was due to the impact of our fixed costs with the lower sales.

        Preclinical Services.    Cost of services provided for the PCS segment for the three months ended June 27, 2009 was $99.2 million, a decrease of $18.5 million, or 15.7%, compared to $117.7 million for the three months ended June 28, 2008. Cost of services provided as a percentage of net sales was 69.6% for the three months ended June 27, 2009, compared to 65.7% for the three months ended

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June 28, 2008. The increase in cost of services provided as a percentage of net sales was primarily due to lower capacity utilization.

        Selling, General and Administrative Expenses.    Selling, general and administrative expenses for the three months ended June 27, 2009 were $56.5 million, a decrease of $4.6 million, or 7.4%, from $61.1 million for the three months ended June 28, 2008. Selling, general and administrative expenses for the three months ended June 27, 2009 were 18.4% of net sales compared to 17.3% of net sales for the three months ended June 28, 2008. The increase as a percentage of sales was due primarily to increased health care costs and a pension curtailment gain in 2008 and lower sales.

        Research Models and Services.    Selling, general and administrative expenses for RMS for the three months ended June 27, 2009 were $18.7 million, a decrease of $5.0 million, or 21.5%, compared to $23.7 million for the three months ended June 28, 2008. Selling, general and administrative expenses decreased as a percentage of sales to 11.2% for the three months ended June 27, 2009 from 13.7% for the three months ended June 28, 2008, due mainly to lower operating expenses in Japan.

        Preclinical Services.    Selling, general and administrative expenses for the PCS segment for the three months ended June 27, 2009 were $21.3 million, a decrease of $4.4 million, or 16.6%, compared to $25.7 million for the three months ended June 28, 2008. Selling, general and administrative expenses for the three months ended June 27, 2009 increased to 15.1% of net sales, compared to 14.3% of net sales for the three months ended June 28, 2008.

        Unallocated Corporate Overhead.    Unallocated corporate overhead, which consists of various costs primarily related to activities centered at our corporate headquarters, such as compensation (including stock-based compensation), information systems, compliance and facilities expenses associated with our corporate, administration and professional services functions was $16.5 million for the three months ended June 27, 2009, compared to $11.7 million for the three months ended June 28, 2008. The increase in unallocated corporate overhead during the second quarter of 2009 was due primarily to growth in health care costs and a pension curtailment gain in 2008.

        Amortization of Other Intangibles.    Amortization of other intangibles for the three months ended June 27, 2009 was $7.3 million, a decrease of $0.3 million, from $7.6 million for the three months ended June 28, 2008.

        Research Models and Services. In the second quarter of 2009, amortization of other intangibles for our RMS segment was $1.7 million, an increase of $1.2 million from $0.5 million in the second quarter of 2008.

        Preclinical Services.    For the three months ended June 27, 2009, amortization of other intangibles for our PCS segment was $5.6 million, compared to $7.1 million for the three months ended June 28, 2008.

        Operating Income.    Operating income for the three months ended June 27, 2009 was $50.7 million, a decrease of $18.6 million, or 26.9%, from $69.3 million for the three months ended June 28, 2008. Operating income for the three months ended June 27, 2009 was 16.4% of net sales, compared to 19.7% of net sales for the three months ended June 28, 2008.

        Research Models and Services.    For the three months ended June 27, 2009, operating income for our RMS segment was $50.8 million, a decrease of $1.4 million, or 2.5%, from $52.2 million for the three months ended June 28, 2008. Operating income as a percentage of net sales for the three months ended June 27, 2009 was 30.7%, compared to 30.2% for the three months ended June 28, 2008. The increase in operating income as a percentage of sales was primarily due to lower operating expenses in Japan.

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        Preclinical Services.    For the three months ended June 27, 2009, operating income for our PCS segment was $16.4 million, a decrease of $12.4 million, or 43.4%, from $28.8 million for the three months ended June 28, 2008. Operating income as a percentage of net sales decreased to 11.5%, compared to 16.1% of net sales for the three months ended June 28, 2008. The decrease in operating income as a percentage of net sales was primarily due to the impact of lower sales.

        Interest Expense.    Interest expense for the three months ended June 27, 2009 was $5.4 million, compared to $5.2 million for the three months ended June 28, 2008. The increase is due to increased interest expense on the convertible debt and reduced capitalized interest and is partially offset by lower debt balances and lower interest rates on outstanding debt.

        Interest Income.    Interest income during the second quarter of 2009 was $0.4 million compared to $2.1 million during the second quarter of 2008 due to lower cash balances and lower interest rates on invested funds worldwide.

        Income Taxes.    Income tax expense for the three months ended June 27, 2009 was $13.6 million, a decrease of $3.5 million compared to $17.1 million for the three months ended June 28, 2008. Our effective tax rate was 28.8% for the second quarter of 2009, compared to 25.9% for the second quarter of 2008. The increase in the effective tax rate in the second quarter of 2009 was primarily due to a decline in Canadian investment tax credits and unbenefitted start-up losses in China.

        Net Income attributable to common shareowners.    Net income attributable to common shareowners in the second quarter of 2009 was $34.2 million, compared to $49.1 million in the same period last year.

Six Months Ended June 27, 2009 Compared to Six Months Ended June 28, 2008

        Net Sales.    Net sales for the six months ended June 27, 2009 were $609.7 million, a decrease of $80.1 million, or 11.6%, from $689.8 million for the six months ended June 28, 2008.

        Research Models and Services.    For the six months ended June 27, 2009, net sales for our RMS segment were $327.2 million, a decrease of $14.2 million, or 4.2%, from $341.4 million for the six months ended June 28, 2008. Unfavorable foreign currency translation decreased sales growth by approximately 4.4%. Lower sales for the Consulting & Staffing Services business and the divestiture of our Vaccine business in Mexico were offset by continued growth of Endotoxin and Microbial Detection products and the addition of MIR Preclinical Services and Piedmont Research Center.

        Preclinical Services.    For the six months ended June 27, 2009, net sales for our PCS segment were $282.5 million, a decrease of $65.9 million, or 18.9%, compared to $348.4 million for the six months ended June 28, 2008. The decrease in PCS sales was primarily due to reduced biopharmaceutical spending and pricing pressure, partially offset by the addition of NewLab BioQuality AG, which we acquired in September of 2008. Unfavorable foreign currency decreased sales growth by 6.0%.

        Cost of Products Sold and Services Provided.    Cost of products sold and services provided for the six months ended June 27, 2009 was $387.0 million, a decrease of $34.4 million, or 8.2%, from $421.4 million for the six months ended June 28, 2008. Cost of products sold and services provided for the six months ended June 27, 2009 was 63.5% of net sales, compared to 61.1% for the six months ended June 28, 2008.

        Research Models and Services.    Cost of products sold and services provided for RMS for the six months ended June 27, 2009 was $187.7 million, a decrease of $1.0 million, or 0.6%, compared to $188.7 million for the six months ended June 28, 2008. Cost of products sold and services provided as a percentage of net sales for the six months ended June 27, 2009 was 57.4% compared to the six months

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ended June 28, 2008 at 55.3% of net sales. The increase in cost as a percentage of sales was due to the impact of our fixed costs with the lower sales.

        Preclinical Services.    Cost of services provided for the PCS segment for the six months ended June 27, 2009 was $199.3 million, a decrease of $33.4 million, or 14.3%, compared to $232.7 million for the six months ended June 28, 2008. Cost of services provided as a percentage of net sales was 70.6% for the six months ended June 27, 2009, compared to 66.8% for the six months ended June 28, 2008. The increase in cost of products sold and services provided as a percentage of net sales was primarily due to lower capacity utilization and severance costs.

        Selling, General and Administrative Expenses.    Selling, general and administrative expenses for the six months ended June 27, 2009 were $118.7 million, a decrease of $1.7 million, or 1.4%, from $120.4 million for the six months ended June 28, 2008. Selling, general and administrative expenses for the six months ended June 27, 2009 were 19.5% of net sales compared to 17.5% of net sales for the six months ended June 28, 2008. The increase in selling, general and administrative expenses as a percent of sales was primarily due to the lower sales.

        Research Models and Services.    Selling, general and administrative expenses for RMS for the six months ended June 27, 2009 were $38.6 million, a decrease of $5.0 million, or 11.5%, compared to $43.6 million for the six months ended June 28, 2008. Selling, general and administrative expenses decreased as a percentage of sales to 11.8% for the six months ended June 27, 2009 from 12.8% for the six months ended June 28, 2008 due mainly to lower operating expenses in Japan.

        Preclinical Services.    Selling, general and administrative expenses for the PCS segment for the six months ended June 27, 2009 were $45.5 million, a decrease of $4.0 million, or 8.0%, compared to $49.5 million for the six months ended June 28, 2008. Selling, general and administrative expenses for the six months ended June 27, 2009 increased to 16.1% of net sales compared 14.2% for the six months ended June 28, 2008, due mainly to lower sales.

        Unallocated Corporate Overhead.    Unallocated corporate overhead, which consists of various costs primarily related to activities centered at our corporate headquarters, such as compensation (including stock-based compensation), information systems, compliance and facilities expenses associated with our corporate, administration and professional services functions was $34.6 million for the six months ended June 27, 2009, compared to $27.3 million for the six months ended June 28, 2008. The increase in unallocated corporate overhead during the first half of 2009 was due primarily to severance charges related to our cost-saving actions and growth in health care costs in addition to a pension curtailment gain recognized in 2008.

        Amortization of Other Intangibles.    Amortization of other intangibles for the six months ended June 27, 2009 was $13.4 million, a decrease of $1.8 million, from $15.2 million for the six months ended June 28, 2008.

        Preclinical Services.    For the six months ended June 27, 2009, amortization of other intangibles for our PCS segment was $10.8 million, a decrease of $3.3 million from $14.1 million for the six months ended June 28, 2008.

        Operating Income.    Operating income for the six months ended June 27, 2009 was $90.6 million, a decrease of $42.2 million, or 31.8%, from $132.8 million for the six months ended June 28, 2008. Operating income for the six months ended June 27, 2009 was 14.9% of net sales, compared to 19.3% of net sales for the six months ended June 28, 2008.

        Research Models and Services.    For the six months ended June 27, 2009, operating income for our RMS segment was $98.3 million, a decrease of $9.7 million, or 9.0%, from $108.0 million for the six months ended June 28, 2008. Operating income as a percentage of net sales for the six months ended

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June 27, 2009 was 30.1%, compared to 31.6% for the six months ended June 28, 2008. The decrease in operating income as a percentage of sales was primarily due to unfavorable capacity utilization.

        Preclinical Services.    For the six months ended June 27, 2009 operating income for our PCS segment was $26.9 million, a decrease of $25.2 million, or 48.4%, from $52.1 million for the six months ended June 28, 2008. Operating income as a percentage of net sales decreased to 9.5%, compared to 15.0% of net sales for the six months ended June 27, 2009. The decrease in operating income as a percentage of net sales was primarily due to lower sales resulting in unfavorable utilization.

        Interest Expense.    Interest expense for the six months ended June 27, 2009 was $10.6 million, compared to $10.4 million for the six months ended June 28, 2008. The increase is due to increased interest expense on the convertible debt and reduced capitalized interest and is partially offset by lower debt balances and lower interest rates on outstanding debt.

        Interest Income.    Interest income for the six months ended June 27, 2009 was $1.0 million compared to $4.8 million for the six months ended June 28, 2008 primarily to lower cash balances and lower interest rates on invested funds.

        Income Taxes.    Income tax expense for the six months ended June 27, 2009 was $23.8 million, a decrease of $9.5 million compared to $33.3 million for the six months ended June 28, 2008. Our effective tax rate was 28.9% for the six months ended June 27, 2009, compared to 26.4% for the six months ended June 28, 2008. The increase in the effective tax rate for the six months ended June 27, 2009 was primarily due to a decline in Canadian investment tax credits and unbenefitted start-up losses in China.

        Net Income attributable to common shareowners.    Net income attributable to common shareowners for the six months ended June 27, 2009 was $59.6 million, compared to the six months ended June 28, 2008 of $93.2 million.

Liquidity and Capital Resources

        The following discussion analyzes liquidity and capital resources by operating, investing and financing activities as presented in our condensed consolidated statements of cash flows.

        Our principal sources of liquidity have been our cash flow from operations, our marketable securities and our revolving line of credit arrangements. During the first quarter of 2009, we repatriated $91.4 million of earnings of our non-U.S. subsidiaries which will be used for general corporate purposes.

        As of June 27, 2009, we had $69.7 million in marketable securities with $50.3 million in time deposits and $19.4 million in auction rate securities rated AAA by a major credit rating agency. Our auction rate securities are guaranteed by U.S. federal agencies. The current overall credit concerns in the capital markets as well as the failed auction status of these securities have impacted our ability to liquidate these investments. If the auctions for the securities we own continue to fail, the investment may not be readily convertible to cash until a future auction of these investments is successful. Based on our ability to access our cash and other short-term investments, our expected operating cash flows, and other sources of cash, we do not anticipate the current lack of liquidity on these investments will affect our ability to operate our business as usual.

        In 2006, we issued $350.0 million of 2.25% Convertible Senior Notes (the 2013 Notes) due in 2013. At June 27, 2009 the fair value of our outstanding 2013 Notes was approximately $316.7 million based on their quoted market value. During the second quarter of 2009, no conversion triggers were met.

        Cash and cash equivalents totaled $154.8 million at June 27, 2009, compared to $243.6 million at December 27, 2008.

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        Net cash provided by operating activities for the six months ending June 27, 2009 and June 28, 2008 was $107.3 million and $126.9 million, respectively. The decrease in cash provided by operations was primarily due to lower earnings. Our days sales outstanding (DSO) increased to 41 days as of June 27, 2009 compared to 40 days as of December 27, 2008 and 39 days as of June 28, 2008. Our DSO includes deferred revenue as an offset to accounts receivable in the calculation.

        Net cash used in investing activities for the six months ending June 27, 2009 and June 28, 2008 was $149.0 million and $70.1 million, respectively. Our capital expenditures during the first six months of 2009 were $45.1 million, of which $13.9 million was related to RMS and $31.2 million to PCS. For 2009, we project capital expenditures to be in the range of $100-$110 million. We anticipate that future capital expenditures will be funded by operating activities and existing credit facilities. During the first half of 2009, we purchased $54.3 million of marketable securities. We paid $51.2 million for acquisitions during 2009, primarily related to our purchase of Piedmont Research Center in the second quarter.

        Net cash used in financing activities for the six months ending June 27, 2009 and June 28, 2008 was $44.4 million and $26.8 million, respectively. During the six months of 2009, we purchased $45.2 million of treasury stock.

New Accounting Pronouncements

        In December 2008, the FASB issued FSP FAS 132 (R)-1, "Employers' Disclosures about Postretirement Benefit Plan Assets." This FSP amends FAS 132, "Employers' Disclosures about Pensions and Other Postretirement Benefits," to provide guidance on an employer's disclosures about plan assets of defined benefit pension or other postretirement plan. The disclosures required by this FSP shall be provided for fiscal years ending after December 15, 2009. Upon initial application, the provisions of this FSP are not required for earlier periods that are presented for comparative purposes. The adoption of this FSP will not have an impact on our consolidated financial statements.

        In June 2009, the FASB issued FAS 168, The FASB Accounting Standards Codification™ and the Hierarchy of Generally Accepted Accounting Principles—a replacement of FASB Statement No. 162 which is effective for financial statements issued for interim and annual periods ending after September 15, 2009. The adoption of this pronouncement will not have an impact on our consolidated financial statements.

        In June 2009, the FASB issued FAS 167, Amendments to FASB Interpretation No. 46(R) effective for fiscal years starting after November 15, 2009, or January 1, 2010 for companies reporting earnings on a calendar-year basis. This statement amends certain requirements of FASB Interpretation No. 46 Consolidation of Variable Interest Entities, to improve financial reporting and to provide more relevant and reliable information to users of financial statements. The adoption of this pronouncement is not expected to have an impact on our financial statements.

        In June 2009, the FASB issued FAS 166, Accounting for Transfers of Financial Assets—an amendment of FASB Statement No. 140 effective for fiscal years beginning after November 15, 2009, or January 1, 2010 for companies reporting earnings on a calendar-year basis. The objective of this statement is to improve the information an entity provides in its financial statements about a transfer of financial assets; the effects of a transfer on its financial position, financial performance, and cash flows; and a transferor's continuing involvement in transferred financial assets. The adoption of this pronouncement is not expected to have an impact on our consolidated financial statements.

Off-Balance Sheet Arrangements

        The conversion features of our 2013 Notes are equity-linked derivatives. As such, we recognize these instruments as off-balance sheet arrangements. The conversion features associated with these notes would be accounted for as derivative instruments, except that they are indexed to our common

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stock and classified in stockholders' equity. Therefore, these instruments meet the scope of exception of paragraph 11(a) of FAS No. 133, Accounting for Derivatives Instruments and Hedging Activities, and are accordingly not accounted for as derivatives for purposes of FAS No. 133.

Item 3.    Quantitative and Qualitative Disclosures About Market Risk

        Certain of our financial instruments are subject to market risks, including interest rate risk and foreign currency exchange rates. We generally do not use financial instruments for trading or other speculative purposes.

Interest Rate Risk

        We have entered into two credit agreements, the amended and restated credit agreement dated July 31, 2006 (credit agreement) and the $50 million credit agreement. Our primary interest rate exposure results from changes in LIBOR or the base rates which are used to determine the applicable interest rates under our term loans and revolving credit facility in the credit agreement and in the $50 million credit agreement. Our potential additional interest expense over one year that would result from a hypothetical, instantaneous and unfavorable change of 100 basis points in the interest rate would be approximately $3.2 million on a pre-tax basis. The book value of our credit agreements approximates fair value.

        We issued $350 million of the 2013 Notes in a private placement in the second quarter of 2006. The convertible senior debenture notes bear an interest rate of 2.25%. The fair market value of the outstanding notes was $316.7 million on June 27, 2009.

Foreign Currency Exchange Rate Risk

        We operate on a global basis and have exposure to some foreign currency exchange rate fluctuations for our earnings and cash flows. This risk is mitigated by the fact that various foreign operations are principally conducted in their respective local currencies. A portion of the revenue from our foreign operations in Canada is denominated in U.S. dollars, with the costs accounted for in their local currencies. We attempt to minimize this exposure by using certain financial instruments, for purposes other than trading, in accordance with our overall risk management and our hedge policy. In accordance with our hedge policy, we designate such transactions as hedges as set forth in FAS 133, Accounting for Derivative Instruments and Hedging Activities.

        During 2009, we utilized foreign exchange contracts, principally to hedge the impact of currency fluctuations on customer transactions and certain balance sheet items. There were no contracts open as of June 27, 2009.

Item 4.    Controls and Procedures

(a)   Evaluation of Disclosure Controls and Procedures

        Based on their evaluation, required by paragraph (b) of Rules 13a-15 or 15d-15, promulgated by the Securities Exchange Act of 1934, the Company's principal executive officer and principal financial officer have concluded that the Company's disclosure controls and procedures as defined in Rules 13a-15(e) and 15d-15(e) of the Exchange Act are effective as of June 27, 2009 to ensure that information required to be disclosed by the Company in reports that it files or submits under the Exchange Act is recorded, processed, summarized and reported within the time periods specified in Securities and Exchange Commission rules and forms. Disclosure controls and procedures include, without limitation, controls and procedures designed to ensure that information required to be disclosed by an issuer in the reports that it files or submits under the Act is accumulated and communicated to the issuer's management, including its principal executive and principal financial

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officers, or persons performing similar functions, as appropriate to allow timely decisions regarding required disclosure. In designing and evaluating the disclosure controls and procedures, our management recognized that any controls and procedures, no matter how well designed and operated, can provide only reasonable assurances of achieving the desired control objectives, and management necessarily was required to apply its judgment in designing and evaluating the controls and procedures. We continually are in the process of further reviewing and documenting our disclosure controls and procedures, and our internal control over financial reporting, and accordingly may from time to time make changes aimed at enhancing their effectiveness and to ensure that our systems evolve with our business.

(b)   Changes in Internal Controls

        There were no changes in the Company's internal controls over financial reporting identified in connection with the evaluation required by paragraph (d) of the Exchange Act Rules 13a-15 or 15d-15 that occurred during the quarter ended June 27, 2009 that materially affected, or were reasonably likely to materially affect, the Company's internal control over financial reporting.

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Part II. Other Information

Item 1A.    Risk Factors

        In addition to the other information set forth in this report, you should carefully consider the factors discussed in Part I, "Item 1A. Risk Factors" in our Annual Report on Form 10-K for the year ended December 27, 2008, which could materially affect our business, financial condition or future results. The risks described in our Annual Report on Form 10-K are not the only risks facing our Company. Additional risks and uncertainties not currently known to us or that we currently deem to be immaterial also may materially adversely affect our business, financial condition and/or operating results. With the exception of the risk factor below, there have been no material changes to the risk factors set forth in our Annual Report on Form 10-k for the year ended December 27, 2008.

Potential Changes in U.S. Tax Law

        In May of 2009, President Obama and the U.S. Treasury Department proposed changing certain of the U.S. tax rules for U.S. corporations doing business outside the United States. The proposed changes include limiting the ability of U.S. corporations to deduct expenses attributable to offshore earnings, modifying the foreign tax credit rules and further restricting the ability of U.S. corporations to transfer funds between foreign subsidiaries without triggering U.S. income tax. Although the scope of the proposed changes is unclear, it is possible that these or other changes in the U.S. tax laws could increase the Company's effective tax rate which would adversely affect our profitability.

Item 2.    Unregistered Sales of Equity Securities and Use of Proceeds

        The following table provides information relating to the Company's purchases of shares of its common stock during the quarter ended June 27, 2009.

        The Board of Directors has authorized a share repurchase program, originally authorized on July 27, 2005 and subsequently amended on October 26, 2005, May 9, 2006, August 1, 2007 and July 24, 2008 to acquire up to a total of $600.0 million of common stock. The program does not have a fixed expiration date.

        During the quarter ended June 27, 2009, the Company repurchased 507,500 shares of common stock for approximately $14.0 million. The timing and amount of any future repurchases will depend on market conditions and corporate considerations. Additionally, the Company's Incentive Plans permit the netting of common stock upon vesting of restricted stock awards in order to satisfy individual tax withholding requirements. During the quarter ended June 27 2009, we acquired 2,794 shares for $78 thousand as a result of such withholdings.

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Item 4.    Submission of Matters to a Vote of Security Holders

        At the Company's Annual Meeting of Shareholders held on May 7, 2009, the following proposals were adopted by the votes specified below:

(a)

The following directors were elected to serve until the Company's 2010 Annual Meeting of Shareholders and received the number of votes listed opposite each of their names below:

(b)

The proposal to amend the Company's 2007 Incentive Plan to increase the number of shares of common stock for issuance under the Plan from 6,300,000 to 8,800,000. A total of 42,546,995 shares voted in favor of the proposal, 14,832,341 shares voted against the proposal, 45,597 shares abstained from voting and there were 3,267,756 broker non-votes.



(c)

The ratification of the appointment of PricewaterhouseCoopers LLP as the Company's independent auditors for fiscal 2009. A total of 60,356,717 shares voted in favor of the ratification, 323,185 shares voted against the ratification, and 12,787 shares abstained from voting.

        Computershare Trust Company, N.A., our transfer agent, acted as independent proxy tabulator and Inspector of Election at the Annual Meeting of Shareholders.

Item 6.    Exhibits

(a)

Exhibits

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SIGNATURES

        Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

		CHARLES RIVER LABORATORIES INTERNATIONAL, INC.
August 5, 2009		/s/ JAMES C. FOSTER James C. Foster Chairman, President and Chief Executive Officer
August 5, 2009		/s/ THOMAS F. ACKERMAN Thomas F. Ackerman Corporate Executive Vice President and Chief Financial Officer

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