Ownership Submission
FORM 3
 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Posard Matthew L.
 2. Date of Event Requiring Statement (Month/Day/Year)
02/02/2012		 3. Issuer Name and Ticker or Trading Symbol
ILLUMINA INC [ILMN]
(Last)
(First)
(Middle)
5200 ILLUMINA WAY		 4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Sr VP & GM, Consumer Genomics
 5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SAN DIEGO, CA 92122		 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)		 2. Amount of Securities Beneficially Owned
(Instr. 4)		 3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)		 4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 16,807 (1)
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)		 2. Date Exercisable and Expiration Date
(Month/Day/Year)		 3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)		 4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)		 6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Non-Qualified Stock Option (right to buy) 02/25/2007(2) 01/25/2017 Common Stock 8,334 $ 20.04 D  
Non-Qualified Stock Option (right to buy) 02/28/2009(3) 01/28/2019 Common Stock 17,580 $ 28.45 D  
Non-Qualified Stock Option (right to buy) 02/29/2008(3) 01/29/2018 Common Stock 5,032 $ 32.485 D  
Non-Qualified Stock Option (right to buy) 02/27/2010(3) 01/27/2020 Common Stock 27,415 $ 37.04 D  
Non-Qualified Stock Option (right to buy) 02/28/2011(3) 01/31/2021 Common Stock 36,225 $ 69.34 D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Posard Matthew L.
5200 ILLUMINA WAY
SAN DIEGO, CA 92122		       Sr VP & GM, Consumer Genomics  

Signatures

By: Scott M. Davies For: Matthew L. Posard 03/07/2012
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) Includes 8,636 unvested restricted stock units which vest as follows: 1,512 shares vest on 1/27/12; 1,960 shares vest on 1/28/12; 800 shares vest on 1/31/12; 1,764 shares vest on 1/27/13; 1,200 shares vest on 1/31/13; 1,400 shares vest on 1/31/14.
(2) One -sixtieth (1/60) of the Shares subject to the Option become exercisable on the date indicated above, subject to Optionee's continuing to be a Service Provider on such date. An additional one -sixtieth (1/60) of the Shares subject to the Option shall become exercisable each full month therafter, subject to Optionee's continuing to be a Service Provider on such date.
(3) One forty-eighth (1/48) of the Shares subject to the Option become exercisable on the date indicated above, subject to Optionee's continuing to be a Service Provider on such date. An additional one-forty eighth (1/48) of the Shares subject to the Option shall become exercisable each full month therafter, subject to Optionee's continuing to be a Service Provider on such date.

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