FORM 4 Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940

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(Print or Type Responses)

1. Name and Address of Reporting Person * Mueller Brian   2. Issuer Name and Ticker or Trading Symbol BIOMARIN PHARMACEUTICAL INC [BMRN] 5. Relationship of Reporting Person(s) to Issuer (Check all applicable) _____ Director _____ 10% Owner __X__ Officer (give title below) _____ Other (specify below) VP, Corporate Controller (Last) (First) (Middle) 105 DIGITAL DRIVE 3. Date of Earliest Transaction (Month/Day/Year) 04/30/2013 (Street) NOVATO, CA 94949 4. If Amendment, Date Original Filed(Month/Day/Year) 6. Individual or Joint/Group Filing(Check Applicable Line) _X_ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person (City) (State) (Zip) Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned

1.Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4) Code V Amount (A) or (D) Price Common Stock 04/30/2013(1)   A V 581 A $ 23.205 13,860 D   Common Stock 05/02/2013 05/02/2013 M   4,874 A $ 14.39 18,734 D   Common Stock 05/02/2013 05/02/2013 S   4,874 D $ 65.346 (2) 13,860 D   Common Stock 05/02/2013 05/02/2013 S   4,457 D $ 65.483 (3) 9,403 D   Common Stock 05/03/2013 05/03/2013 M   7,500 A $ 21.51 16,903 D   Common Stock 05/03/2013 05/03/2013 S   7,500 D $ 67.106 (4) 9,403 D

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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)

1. Title of Derivative Security (Instr. 3)

2. Conversion or Exercise Price of Derivative Security

3. Transaction Date (Month/Day/Year)

3A. Deemed Execution Date, if any (Month/Day/Year)

4. Transaction Code (Instr. 8)

5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4, and 5)

6. Date Exercisable and Expiration Date (Month/Day/Year)

7. Title and Amount of Underlying Securities (Instr. 3 and 4)

8. Price of Derivative Security (Instr. 5)

9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)

10. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 4)

11. Nature of Indirect Beneficial Ownership (Instr. 4)

Code

V

(A)

(D)

Date Exercisable

Expiration Date

Title

Amount or Number of Shares

Stock Option (right to buy) Common Stock

$ 21.51

05/02/2013

05/02/2013

M

7,500

11/12/2010(6)

05/11/2020

Common Stock

7,500

$ 0

15,200 (7)

D

Stock Option (right to buy) Common Stock

$ 14.39

05/03/2013

05/03/2013

M

4,874

11/12/2009(5)

05/11/2019

Common Stock

4,874

$ 0

521 (7)

D

Reporting Owners

Reporting Owner Name / Address	Relationships
	Director	10% Owner	Officer	Other
Mueller Brian 105 DIGITAL DRIVE NOVATO, CA 94949			VP, Corporate Controller

Signatures

/s/ Laura Randall Woodhead, Attorney-in-Fact		05/06/2013
**Signature of Reporting Person		Date

Explanation of Responses:

*	If the form is filed by more than one reporting person, see Instruction 4(b)(v).
**	Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1)	The reporting person is reporting the acquisition of shares of the issuer's Employee Stock Purchase Plan ("ESPP"), for the ESPP purchase period of November 1, 2012 to April 30, 2013.
(2)	The price in column 4 is a weighted average price. The price actually received ranged from $65.385 to $65.344. The reportng person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
(3)	The price in column 4 is a weighted average price. The price actually received ranged from $65.481 to $65.472. The reportng person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
(4)	The price in column 4 is a weighted average price. The price actually received ranged from $67.105 to $67.16. The reportng person will provide to the issuer, any security holder of the issuer, or the SEC staff, upon request, information regarding the number of shares sold at each price within the range.
(5)	Original option grant vests 6/48th on November 12, 2009 and 1/48th each on the 12th of each month thereafter.
(6)	Original option grant vests 6/48th on November 12, 2010 and 1/48th each on the 12th of each month thereafter.
(7)	Reflects the number of stock options that remain outstanding from this specific stock option grant following the reported transaction.

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