Free Writing Prospectus

Issuer Free Writing Prospectus

Filed Pursuant to Rule 433

Registration Statement No. 333-132566

(Supplementing Preliminary Prospectus Supplements dated March 20, 2006)

~ Sole-Bookrun Add-on & SEC-Registered Senior Subordinated Convertible Notes Pricing ~

 


LOGO

BioMarin Pharmaceutical, Inc.

(BMRN/NASDAQ & SWX)

 


Common Stock Add-On Offering

Offering Size: 9,000,000 Shares (100% Primary)

Greenshoe (15%): 1,350,000 Shares (100% Primary)

Price: $13.00

Last Sale (3/23/06): $13.13

Net Proceeds: $111,150,000

Trade Date: 3/23/2006

Settlement Date: 3/29/2006

CUSIP: 09061G101

Sole-Bookrunner: Merrill Lynch

Co-Managers: SG Cowen, Leerink Swann, Pacific Growth and Rodman & Renshaw

SEC-Registered Senior Subordinated Convertible Notes

Offering Size: $150,000,000

Greenshoe (15%): $22,500,000

Public Offering Price: $1,000.00 per note (100%)

Net Proceeds: $ 145,500,000

Maturity: March 29, 2013

Interest Rate: 2.50% payable semiannually in arrears in cash

Last Sale (3/23/06): $13.13

Reference Price: $13.00

Conversion Price: $16.58, subject to adjustment

Conversion Premium: 27.50%

Conversion Rate: 60.3318, subject to adjustment

Interest Payment Dates: March 29 and September 29, beginning September 29, 2006

Make-Whole Premium Upon a Fundamental Change: If a fundamental

change occurs and a holder elects to convert in connection with such

transaction, the conversion rate will be increased by a number of shares.


The number of additional shares will be determined by reference to the following table and is based on the date on which such fundamental change becomes effective and the price paid per share of common stock on the effective date:

 

    

Effective Date

Stock Price on

Effective Date

   3/29/2006    3/29/2007    3/29/2008    3/29/2009    3/29/2010    3/29/2011    3/29/2012    3/29/2013

$13.00

   16.5913    16.5913    16.5913    16.5913    16.5913    16.5913    16.5913    0.0000

  15.00

   12.6663    12.9378    13.1829    13.3647    13.3613    12.9979    11.7576    0.0000

  17.50

   9.2976    9.3644    9.3828    9.3121    9.0334    8.3743    6.8025    0.0000

  20.00

   6.9641    6.9180    6.8082    6.6020    6.1983    5.4322    3.8758    0.0000

  22.50

   5.3608    5.1665    4.9946    4.7229    4.2680    3.5059    2.1229    0.0000

  25.00

   4.8289    4.3311    3.7837    3.3693    2.9181    2.2103    1.0502    0.0000

  27.50

   4.3856    3.9347    3.4421    2.8881    2.2799    1.5994    0.8419    0.0000

  30.00

   4.0272    3.6079    3.1567    2.6464    2.0829    1.4645    0.7716    0.0000

  35.00

   3.4457    3.0987    2.7100    2.2684    1.7843    1.2508    0.6581    0.0000

  40.00

   3.0253    2.7037    2.3724    1.9884    1.5626    1.0952    0.5748    0.0000

  45.00

   2.6976    2.4108    2.1138    1.7707    1.3932    0.9751    0.5093    0.0000

  50.00

   2.4278    2.1705    1.8893    1.5955    1.2573    0.8796    0.4620    0.0000

  55.00

   2.2023    1.9778    1.7196    1.4547    1.1416    0.7975    0.4225    0.0000

  60.00

   2.0281    1.8157    1.5732    1.3353    1.0485    0.7362    0.3879    0.0000

  70.00

   1.7303    1.5553    1.3565    1.1486    0.8969    0.6317    0.3330    0.0000

  80.00

   1.5176    1.3630    1.1852    1.0087    0.7874    0.5537    0.2902    0.0000

  90.00

   1.3574    1.2119    1.0617    0.8946    0.6991    0.4902    0.2581    0.0000

100.00

   1.2186    1.0957    0.9566    0.8038    0.6285    0.4413    0.2323    0.0000

Trading: The notes will not be listed on any securities exchange or included

in any automatic quotation system.

Trade Date: 3/23/2006

Settlement Date: 3/29/2006

CUSIP: 09061G AC 5

Sole-Manager: Merrill Lynch

******

The issuer has filed a registration statement (including a prospectus and supplements thereto) with the SEC for the offerings to which this communication relates. Before you invest, you should read the prospectus and the supplements thereto in that registration statement and other documents the issuer has filed with the SEC for more complete information about the issuer and these offerings. You may get these documents for free by visiting EDGAR on the SEC Web site at www.sec.gov. Alternatively, the issuer, any underwriter or any dealer participating in the offering will arrange to send you the prospectus and the supplements thereto if you request them by calling toll-free 1-866-500-5408.

ANY DISCLAIMERS OR OTHER NOTICES THAT MAY APPEAR BELOW ARE NOT APPLICABLE TO THIS COMMUNICATION AND SHOULD BE DISREGARDED. SUCH DISCLAIMERS OR OTHER NOTICES WERE AUTOMATICALLY GENERATED AS A RESULT OF THIS COMMUNICATION BEING SENT VIA BLOOMBERG OR ANOTHER EMAIL SYSTEM.