Ownership Submission
FORM 3
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934, Section 17(a) of the Public Utility Holding Company Act of 1935 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
  Gano Kyle
2. Date of Event Requiring Statement (Month/Day/Year)
01/16/2013
3. Issuer Name and Ticker or Trading Symbol
NEUROCRINE BIOSCIENCES INC [NBIX]
(Last)
(First)
(Middle)
NEUROCRINE BIOSCIENCES, INC., 12780 EL CAMINO REAL
4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
_____ Director _____ 10% Owner
__X__ Officer (give title below) _____ Other (specify below)
Chief Business Dev Officer
5. If Amendment, Date Original Filed(Month/Day/Year)
(Street)

SAN DIEGO, CA 92130
6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Beneficially Owned
1.Title of Security
(Instr. 4)
2. Amount of Securities Beneficially Owned
(Instr. 4)
3. Ownership Form: Direct (D) or Indirect (I)
(Instr. 5)
4. Nature of Indirect Beneficial Ownership
(Instr. 5)
Common Stock 22,488
D
 

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. SEC 1473 (7-02)
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Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 4)
2. Date Exercisable and Expiration Date
(Month/Day/Year)
3. Title and Amount of Securities Underlying Derivative Security
(Instr. 4)
4. Conversion or Exercise Price of Derivative Security 5. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 5)
6. Nature of Indirect Beneficial Ownership
(Instr. 5)
Date Exercisable Expiration Date Title Amount or Number of Shares
Employee Stock Option (right to buy)   (1) 09/26/2013 Common Stock 2,400 $ 10.9 D  
Employee Stock Option (right to buy)   (2) 03/12/2015 Common Stock 9,000 $ 5 D  
Employee Stock Option (right to buy)   (3) 05/11/2017 Common stock 40,000 $ 2.59 D  
Employee Stock Option (right to buy)   (4) 08/25/2021 Common Stock 75,000 $ 5.76 D  
Employee Stock Option (right to buy)   (5) 01/12/2022 Common Stock 70,000 $ 8.66 D  
Employee Stock Option (right to buy)   (6) 01/10/2023 Common Stock 60,000 $ 8.65 D  
Restricted Stock Unit   (7)   (7) Common Stock 10,000 $ 0 (8) D  

Reporting Owners

Reporting Owner Name / Address Relationships
Director 10% Owner Officer Other
Gano Kyle
NEUROCRINE BIOSCIENCES, INC.
12780 EL CAMINO REAL
SAN DIEGO, CA 92130
      Chief Business Dev Officer  

Signatures

Margaret E. Valeur- Jensen, By Power of Attorney 01/28/2013
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 5(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
(1) The option vested in annual installments over three years. The first installment became exercisable on September 26, 2007.
(2) The option vested in annual installments over three years. The first installment became exercisable on March 12, 2009.
(3) The option vests in monthly installments over three years. The first installment became exercisable on June 11, 2010.
(4) The option vests in monthly installments over three years. The first installment became exercisable on September 25, 2011.
(5) The option vests in monthly installments over four years. The first installment became exercisable on February 12, 2012.
(6) The option vests in monthly installments over four years. The first installment becomes exercisable on February 10, 2013.
(7) The restricted stock units will vest annually at 1/4 of the units vesting on January 10, 2014, January 10, 2015, January 10, 2016 and January 10, 2017, respectively.
(8) Each restricted stock unit represents a contingent right to receive one share of Neurocrine Biosciences, Inc. Common Stock.

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