SECURITIES AND EXCHANGE COMMISSION
                              WASHINGTON, DC 20549

                                  SCHEDULE 13G
                                 (Rule 13d-102)

     INFORMATION TO BE INCLUDED IN THE STATEMENTS FILED PURSUANT TO RULES
     13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b)

                               (Amendment No. 2)*

                               DOR BIOPHARMA, INC.
                               -------------------
                                (Name of Issuer)

                     Common Stock, par value $.001 per share
                     ---------------------------------------
                         (Title of Class of Securities)

                                    258094101
                                  ------------
                                 (CUSIP Number)

                                February 9, 2005
--------------------------------------------------------------------------------
            (Date of Event Which Requires Filing of this Statement)


Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

     [ ]  Rule 13d-1(b)

     [X]  Rule 13d-1(c)

     [ ]  Rule 13d-1(d)

*The remainder of this cover page shall be filled out for a reporting person's
initial filing on this form with respect to the subject class of securities, and
for any subsequent amendment containing information which would alter the
disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

                                  SCHEDULE 13G

CUSIP NO. 258094101                                                 Page 2 of 6
_____________________________________________________________________________
     NAMES OF REPORTING PERSONS
     I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (Entities Only)
1
     Michael A. Roth and Brian J. Stark, as joint filers pursuant to
     Rule 13d-1(k)
_____________________________________________________________________________
2    CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP                (a) [X]
                                                                     (b) [ ]
_____________________________________________________________________________
3    SEC USE ONLY
_____________________________________________________________________________
4    CITIZENSHIP OR PLACE OF ORGANIZATION

     United States of America
_____________________________________________________________________________

NUMBER OF      5    SOLE VOTING POWER

SHARES              0
               ______________________________________________________________
BENEFICIALLY   6    SHARED VOTING POWER

OWNED BY            3,817,046 (See Item 4)
               ______________________________________________________________
EACH           7    SOLE DISPOSITIVE POWER

REPORTING           0
               ______________________________________________________________
PERSON         8    SHARED DISPOSITIVE POWER

WITH                3,817,046 (See Item 4)
_____________________________________________________________________________
9    AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

     3,817,046 (See Item 4)
_____________________________________________________________________________
10   CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES
                                                                          [X]
_____________________________________________________________________________
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)

     7.6% (See Item 4)
_____________________________________________________________________________
12   TYPE OF REPORTING PERSON

     IN
_____________________________________________________________________________

                                  SCHEDULE 13G

CUSIP NO. 258094101                                                 Page 3 of 6

Item 1(a).     Name of Issuer:

               DOR BioPharma, Inc. (the "Issuer")

Item 1(b).     Address of Issuer's Principal Executive Offices:

               1691 Michigan Avenue
               Suite 435
               Miami, FL 33139

Items 2(a),
(b) and (c).   Name of Persons Filing, Address of Principal Business Office and
               Citizenship:

               This  Amendment No. 2 to Schedule 13G is being filed on behalf of
               Michael   A.  Roth  and   Brian  J.   Stark,   as  joint   filers
               (collectively, the "Reporting Persons").

               The Reporting Persons have entered into a Joint Filing Agreement,
               a copy of which is filed with this  Amendment No. 2 to  Schedule
               13G as Exhibit 1,  pursuant to which the  Reporting  Persons have
               agreed to file this  Amendment  No. 2 to Schedule  13G jointly in
               accordance with the provisions of Rule 13d-1(k) of the Securities
               Exchange Act of 1934, as amended.

               The principal  business  office of the Reporting  Persons is 3600
               South Lake Drive, St. Francis, WI 53235.

Item 2(d).     Title of Class of Securities:

               Common  Stock,  par value  $.001 per share,  of the  Issuer  (the
               "Common Stock")

Item 2(e).     CUSIP Number:

               258094101

Item 3.        Not applicable.

Item 4.        Ownership.

               (a)  Amount beneficially owned:

                    3,817,046 shares of Common Stock*

               (b)  Percent of class:

                    Based on  42,042,943  shares of Common  Stock of the  Issuer
                    outstanding  as of  November  1,  2004 (as set  forth in the
                    Issuer's  Form  10-QSB for the period  ended  September  30,
                    2004),  and  8,396,100  shares of Common Stock of the Issuer
                    issued in connection with the Issuer's private placement (as
                    set forth in the Issuer's Form 8-K dated  February 1, 2005),


                                  SCHEDULE 13G

CUSIP NO. 258094101                                                 Page 4 of 6

                    the Reporting Persons hold approximately 7.6%* of the issued
                    and outstanding Common Stock of the Issuer.

              (c)   Number of shares to which such person has:

                    (i)   Sole power to vote or direct the vote: 0

                    (ii)  Shared power to vote or direct the vote: 3,817,046*

                    (iii) Sole power to dispose or to direct the disposition of:
                          0

                    (iv)  Shared  power to dispose of or direct the  disposition
                          of: 3,817,046*

                    *The  Reporting  Persons  beneficially  own an  aggregate of
                    3,817,046  shares of Common Stock.  The foregoing  amount of
                    Common Stock and percentage ownership represent the combined
                    indirect holdings of Michael A. Roth and Brian J. Stark. The
                    shares of Common Stock  reported in this  Amendment No. 2 to
                    Schedule 13G do not include  certain  shares of Common Stock
                    issuable upon the exercise of warrants held by the Reporting
                    Persons.  Such warrants  held by the  Reporting  Persons are
                    subject to conversion  caps that preclude the holder thereof
                    from  utilizing  its  exercise  rights to the extent that it
                    would   beneficially  own  (determined  in  accordance  with
                    Section  13(d) of the  Securities  Exchange  Act of 1934) in
                    excess of 4.999%  and  9.999% of the  Common  Stock,  giving
                    effect to such exercise.

                    All of the  foregoing  represents  an aggregate of 3,817,046
                    shares of Common Stock held directly by SF Capital  Partners
                    Ltd. ("SF Capital").  The Reporting Persons are the Managing
                    Members   of  Stark   Offshore   Management,   LLC   ("Stark
                    Offshore"),  which acts as  investment  manager and has sole
                    power to direct the management of SF Capital.  Through Stark
                    Offshore,   the  Reporting   Persons   possess   voting  and
                    dispositive   power  over  all  of  the  foregoing   shares.
                    Therefore, for the purposes of Rule 13d-3 under the Exchange
                    Act,  the  Reporting   Persons  may  be  deemed  to  be  the
                    beneficial  owners of, but hereby  disclaim such  beneficial
                    ownership of, the foregoing shares.

Item 5.        Ownership of Five Percent or Less of a Class.

               Not applicable.

Item 6.        Ownership of More than Five Percent on Behalf of Another Person.

               Not applicable.

Item 7.        Identification  and Classification of the Subsidiary Which
               Acquired the Security Being Reported By the Parent Holding
               Company.

               Not applicable.

Item 8.        Identification and Classification of Members of the Group.



                                  SCHEDULE 13G

CUSIP NO. 258094101                                                 Page 5 of 6

               Not applicable.

Item 9.        Notice of Dissolution of a Group.

               Not applicable.

Item 10.       Certification.

               By signing  below I certify that, to the best of my knowledge and
               belief,  the  securities  referred to above were not acquired and
               are not held for the purpose of or with the effect of changing or
               influencing  the control of the issuer of the securities and were
               not  acquired  and  are  not  held  in  connection  with  or as a
               participant in any transaction having that purpose or effect.


                                  SCHEDULE 13G

CUSIP NO. 258094101                                                 Page 6 of 6


                                    SIGNATURE

     After  reasonable  inquiry and to the best of my  knowledge  and belief,  I
certify that the information  set forth in this statement is true,  complete and
correct.

Dated:   February 15, 2005



                                            /s/ Michael A. Roth
                                            --------------------------
                                            Michael A. Roth


                                            /s/ Brian J. Stark
                                            --------------------------
                                            Brian J. Stark



                                  SCHEDULE 13G

CUSIP NO. 258094101                                                 
                                                                      Exhibit 1

                             JOINT FILING AGREEMENT

     In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934,
as amended,  the undersigned agree to the joint filing on behalf of each of them
of a statement on Amendment No. 2 to Schedule 13G (including amendments thereto)
with respect to 3,817,046  shares of Common Stock,  of DOR  BioPharma,  Inc. and
further agree that this Joint Filing  Agreement  shall be included as an exhibit
to such joint filings.

     The undersigned further agree that each party hereto is responsible for the
timely  filing  of such  Amendment  No.  2 to  Schedule  13G and any  amendments
thereto,  and for the  completeness  and accuracy of the information  concerning
such party contained therein;  provided,  however,  that no party is responsible
for the  completeness or accuracy of the information  concerning any other party
making the filing,  unless  such party knows or has reason to believe  that such
information is inaccurate.

     IN WITNESS  WHEREOF,  the parties have executed this Joint Filing Agreement
on February 15, 2005.


                                              /s/ Michael A. Roth
                                            --------------------------
                                            Michael A. Roth


                                            /s/ Brian J. Stark
                                            --------------------------
                                            Brian J. Stark