Genprex (NASDAQ: GNPX), a clinical-stage gene therapy company focused on developing life-changing treatments for patients with cancer and diabetes, today announced that its Chief Manufacturing and Technology Officer Hemant Kumar, Ph.D. will participate in the upcoming Bioprocessing Summit Europe Conference taking place March 14-16, 2023, in Barcelona, Spain. Dr. Kumar is scheduled to present at 8:30 a.m. Central European Time on Wednesday, March 15. “Dramatic increase in mergers and acquisitions within the global CDMO market has changed the landscape for advancing the development of disruptive innovative gene therapies. This has encouraged CDMOs to provide integrated services to advance drug development but can be a financial burden on clinical stage companies due to potentially higher costs for services and licensing fees, and can add delays in timelines for regulatory submissions,” noted Dr. Kumar. “Managing these headwinds through better partnership with CDMOs is key to overcoming these challenges as together we work to bring life-altering new gene therapy treatments to patients battling diseases of unmet medical need.”
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About Genprex Inc.
Genprex is a clinical-stage gene therapy company focused on developing life-changing treatments for patients with cancer and diabetes. Genprex’s technologies are designed to administer disease-fighting genes to provide new therapies for large patient populations with cancer and diabetes who currently have limited treatment options. Genprex works with world-class institutions and collaborators to develop drug candidates to further its pipeline of gene therapies in order to provide novel treatment approaches. Genprex’s oncology program utilizes its proprietary, non-viral ONCOPREX(R) Nanoparticle Delivery System, which the company believes is the first systemic gene therapy delivery platform used for cancer in humans. ONCOPREX encapsulates the gene-expressing plasmids using lipid nanoparticles. The resultant product is administered intravenously, where it is then taken up by tumor cells that express tumor suppressor proteins that are deficient in the body. The company’s lead product candidate, REQORSA(R) (quaratusugene ozeplasmid), is being evaluated in three clinical trials as a treatment for non-small cell lung cancer (“NSCLC”) and small cell lung cancer (“SCLC”). Both NSCLC clinical programs received a Fast Track Designation from the Food and Drug Administration. Genprex’s diabetes gene therapy approach is comprised of a novel infusion process that uses an endoscope and an adeno-associated virus (“AAV”) vector to deliver Pdx1 and MafA genes directly to the pancreas. In models of type 1 diabetes, GPX-002 transforms alpha cells in the pancreas into functional beta-like cells, which can produce insulin but are distinct enough from beta cells to evade the body’s immune system. In a similar approach, GPX-003 for type 2 diabetes, where autoimmunity is not at play, is believed to rejuvenate and replenish exhausted beta cells. For more information, visit the company’s website at www.Genprex.com.
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