United States Securities And Exchange Commission
                              Washington, DC 20549
--------------------------------------------------------------------------------

                                   FORM 10-QSB
(Mark One)

|X|  Quarterly  Report under Section 13 or 15(d) of the Securities  Exchange Act
     of 1934

     For  the quarterly period ended March 31, 2003

OR

|_|  Transition Report under Section 13 or 15(d) of the Securities  Exchange Act
     of 1934

     For  the transition period from __________ to _______________

                         Commission file number: 0-9410

                         Provectus Pharmaceuticals, Inc.
        (Exact Name of Small Business Issuer as Specified in Its Charter)

         Nevada                                           90-0031917
---------------------------------------         --------------------------------
(State or other jurisdiction of                         (I.R.S. Employer
 incorporation or organization)                       Identification Number)

 7327 Oak Ridge Highway Suite A, Knoxville, TN               37931
-----------------------------------------------   ------------------------------
(Address of Principal Executive Offices)                  (Zip Code)

                                  865/769-4011
--------------------------------------------------------------------------------
                (Issuer's Telephone Number, Including Area Code)

                                      N/A
--------------------------------------------------------------------------------
(Former Name, Former Address and Former Fiscal Year, if Changed Since Last
 Report)

     Check  whether  the issuer:  (1) filed all reports  required to be filed by
Section 13 or 15(d) of the Securities  Exchange Act of 1934 during the preceding
12 months (or for such shorter  period that the  registrant was required to file
such reports), and (2) has been subject to such filing requirements for the past
90 days. Yes |X| No |_|

     The number of shares  outstanding of the issuer's  stock,  $0.001 par value
per share, as of May 6, 2003 was 9,487,689.

     Transitional Small Business Disclosure Format (check one): Yes |_| No |X|

                                Table of Contents
                                                                            Page

Part I Financial Information...................................................1

   Item 1.    Financial Statements.............................................1
       Index To Consolidated Financial Statements..............................1
       Consolidated Balance Sheets.............................................2
       Consolidated Statements of Operations...................................3
       Consolidated Statements of Stockholders' Equity.........................4
       Consolidated Statements of Cash Flows...................................5
       Notes to Consolidated Financial Statements..............................6

   Item 2.    Management's Discussion and Analysis or Plan of Operation........8
       Overview................................................................8
       Going Concern..........................................................10
       Plan of Operation......................................................11
       Forward-Looking Statements.............................................14

   Item 3.    Controls and Procedures.........................................14

Part II Other Information.....................................................15

   Item 1.    Legal Proceedings...............................................15

   Item 2.    Changes in Securities and Use of Proceeds.......................15

   Item 3.    Defaults Upon Senior Securities.................................16

   Item 4.    Submission of Matters to a Vote of Security Holders.............16

   Item 5.    Other Information...............................................17

   Item 6.    Exhibits and Reports on Form 8-K................................17

Signatures....................................................................18

Certification of Chief Executive Officer......................................19

Certification of Chief Financial Officer......................................20

Exhibit Index................................................................X-1

                                       i


                                     Part I
                              Financial Information

   Item 1. Financial Statements.

   INDEX TO CONSOLIDATED FINANCIAL STATEMENTS
                                                                            Page

     Consolidated Balance Sheets...............................................2
     Consolidated Statements of Operations.....................................3
     Consolidated Statements of Stockholders' Equity...........................4
     Consolidated Statements of Cash Flows.....................................5
     Notes to Consolidated Financial Statements................................6


                                       1

                         Provectus Pharmaceuticals, Inc.
                          (A Development-Stage Company)

                           Consolidated Balance Sheets



                                                                                 March 31,         December 31,
                                                                                      2003                 2002
------------------------------------------------------------------------------------------------------------------
                                                                                 (Unaudited)           (Audited)
                                                                                                   
Assets

Current Assets
     Cash                                                                  $       140,261    $         717,833
     Prepaid expenses                                                               32,982               35,481
     Prepaid consulting expense (Note 6(b))                                         74,917                    -
------------------------------------------------------------------------------------------------------------------

Total Current Assets                                                               248,160              753,314

Equipment and Furnishings, less accumulated depreciation of
     $123,327 and $39,446                                                          390,849              471,429

Patents, net of amortization of $420,879 and $133,916                           19,616,681           19,903,644

Other Assets                                                                        27,000               27,000
------------------------------------------------------------------------------------------------------------------

                                                                           $    20,282,690    $      21,155,387
------------------------------------------------------------------------------------------------------------------

Liabilities and Stockholders' Equity

Current Liabilities
     Accounts payable - trade                                              $        52,572    $          98,874
     Accrued expenses                                                               85,250               77,781
------------------------------------------------------------------------------------------------------------------

Total Current Liabilities                                                          137,822              176,655

Loan From Stockholder                                                              109,000              109,000

Convertible Long-Term Debt (net of debt discount of $104,774
     and $120,344) (Note 5)                                                        921,185              879,656

Stockholders' Equity
     Common stock;  par value $.001 per share;  100,000,000  shares
        authorized; 9,487,689 and 9,423,689 shares issued and
        outstanding, respectively                                                    9,488                9,424
     Paid-in capital                                                            27,219,633           27,102,406
     Accumulated deficit                                                        (8,114,438)          (7,121,754)
------------------------------------------------------------------------------------------------------------------

Total Stockholders' Equity                                                      19,114,683           19,990,076
------------------------------------------------------------------------------------------------------------------

                                                                           $    20,282,690    $      21,155,387
------------------------------------------------------------------------------------------------------------------

                 See accompanying notes to financial statements.

                                       2

                         Provectus Pharmaceuticals, Inc.
                          (A Development-Stage Company)

                      Consolidated Statements of Operations



                                                                   Three                 Three         Cumulative
                                                            Months Ended          Months Ended            Through
                                                               March 31,             March 31,          March 31,
                                                                    2003                  2002               2003
-------------------------------------------------------------------------------------------------------------------
                                                               (Unaudited)           (Unaudited)        (Unaudited)
                                                                                         
Operating Expenses
     Research and development                               $    155,783          $      1,000        $   206,497
     General and administrative                                  511,917                10,000          7,434,863
     Amortization                                                286,963                     -            420,879
-------------------------------------------------------------------------------------------------------------------

Total operating loss                                            (954,663)              (11,000)        (8,062,239)

Net interest (expense) income                                    (38,021)                   34            (52,199)
-------------------------------------------------------------------------------------------------------------------

Net Loss Applicable to Common
     Stockholders                                           $   (992,684)         $    (10,966)       $(8,114,438)
-------------------------------------------------------------------------------------------------------------------

Basic and Diluted Loss Per Common Share                            (0.11)                    -
-------------------------------------------------------------------------------------------------

Weighted Average Number of Common
     Shares Outstanding - Basic and Diluted                    9,451,667             6,230,137
-------------------------------------------------------------------------------------------------




                 See accompanying notes to financial statements.

                                      3



                        Provectus Pharmaceuticals, Inc.
                          (A Development-Stage Company)

                 Consolidated Statements of Stockholders' Equity
                                  (unaudited)



------------------------------------------------------------------------------------------------------------------------------------
                                                                Common Stock
                                                        ------------------------------
                                                        ------------------------------
                                                           Number of                        Paid-in     Accumulated
                                                              Shares       Par Value        Capital         Deficit           Total
------------------------------------------------------------------------------------------------------------------------------------
------------------------------------------------------------------------------------------------------------------------------------

                                                                                                                
Balance, at January 17, 2002                                       -       $       -   $          -     $         -     $         -

     Issuance to founding stockholders                     6,000,000           6,000         (6,000)              -               -
     Sale of stock                                            50,000              50         24,950               -          25,000
     Issuance of stock to employees                          510,000             510        931,490               -         932,000
     Issuance of stock for services                          120,000             120        359,880               -         360,000
     Net loss for the period from January 17, 2002
      (inception)
         to April 23, 2002 (date of reverse merger)                -               -              -      (1,316,198)     (1,316,198)
------------------------------------------------------------------------------------------------------------------------------------

Balance, at April 23, 2002                                 6,680,000           6,680      1,310,320      (1,316,198)            802

     Shares issued in reverse merger                         265,763             266         (3,911)              -          (3,645)
     Issuance of stock for services                        1,900,000           1,900      5,142,100               -       5,144,000
     Purchase and retirement of stock                       (400,000)           (400)       (47,600)              -         (48,000)
     Stock issued for acquisition of Valley
      Pharmaceuticals                                        500,007             500     20,547,935               -      20,548,435
     Exercise of warrants                                    452,919             453              -               -             453
     Warrants issued in connection with convertible debt           -               -        126,587               -         126,587
     Stock and warrants issued for acquisition of
      Pure-ific                                               25,000              25         26,975               -          27,000
     Net loss for the period from April 23, 2002 (date
      of reverse merger) to December 31, 2002                      -               -              -      (5,805,556)     (5,805,556)
------------------------------------------------------------------------------------------------------------------------------------

Balance, at December 31, 2002                              9,423,689           9,424     27,102,406      (7,121,754)     19,990,076

     Issuance of stock for services                           64,000              64         22,736               -          22,800
     Issuance of warrants for services                             -               -         94,491               -          94,491
     Net loss for the three months ended March 31, 2003            -               -              -        (992,684)       (992,684)
------------------------------------------------------------------------------------------------------------------------------------

                                                           9,487,689       $   9,488   $ 27,219,633     $(8,114,438)    $19,114,683
------------------------------------------------------------------------------------------------------------------------------------


                 See accompanying notes to financial statements.

                                      4


                        Provectus Pharmaceuticals, Inc.
                          (A Development-Stage Company)

                      Consolidated Statements of Cash Flows



                                                                                     For the Period            Cumulative
                                                                    Three          From January 17,          Amounts From
                                                             Months Ended       2002 (Inception) to      January 17, 2002
                                                           March 31, 2003            March 31, 2002           (Inception)
----------------------------------------------------------------------------------------------------------------------------
                                                             (Unaudited)              (Unaudited)             (Unaudited)
                                                                                                         
Cash Flows From Operating Activities
     Net loss                                                $   (992,684)             $    (10,966)          $(8,114,438)
     Adjustments to reconcile net income to
         net cash used in operating activities
         Depreciation                                              83,881                         -               123,327
         Amortization of patents                                  286,963                         -               420,879
         Amortization of original issue discount                   15,570                         -                21,813
         Compensation through issuance of
              stock                                                     -                         -               932,000
         Issuance of stock for services                            22,800                         -             5,526,800
         Issuance of warrants for services                         19,574                         -                19,574
         (Increase) decrease in assets
              Prepaid expenses                                      2,499                         -               (32,982)
         Increase (decrease) in liabilities
              Accounts payable                                    (46,302)                        -                48,927
              Accrued expenses                                      7,469                         -                85,250
----------------------------------------------------------------------------------------------------------------------------

Net cash used in operating activities                            (600,230)                  (10,966)             (968,850)
----------------------------------------------------------------------------------------------------------------------------

Cash Flows From Investing Activities
     Capital expenditures                                          (3,301)                        -                (3,301)
----------------------------------------------------------------------------------------------------------------------------

Net cash used in investing activities                              (3,301)                        -                (3,301)
----------------------------------------------------------------------------------------------------------------------------

Cash Flows From Financing Activities
     Proceeds from loans from stockholder                               -                         -               109,000
     Proceeds from convertible debt                                25,959                         -             1,025,959
     Proceeds from sale of common stock                                 -                    25,000                25,000
     Proceeds from exercise of warrants                                 -                         -                   453
     Purchase and retirement of common stock                            -                         -               (48,000)
----------------------------------------------------------------------------------------------------------------------------

Net cash provided by financing activities                          25,959                    25,000             1,112,412
----------------------------------------------------------------------------------------------------------------------------

Net Change in Cash                                           $   (577,572)             $     14,034           $   140,261

Cash, at beginning of period                                      717,833                         -                     -
----------------------------------------------------------------------------------------------------------------------------

Cash, at end of period                                       $    140,261              $     14,034           $   140,261
----------------------------------------------------------------------------------------------------------------------------


Supplemental Noncash Financing Activities
     Warrants issued to consultants for prepaid services of $74,917 in 2003.


                 See accompanying notes to financial statements.

                                      5


                        Provectus Pharmaceuticals, Inc.
                          (A Development-Stage Company)

                   Notes to Consolidated Financial Statements
                                  (unaudited)

1.   BASIS OF PRESENTATION

     The  accompanying   unaudited  condensed  financial  statements  have  been
prepared in accordance with generally accepted accounting principles for interim
financial  information  pursuant to  Regulation  S-K.  Accordingly,  they do not
include all of the  information  and  footnotes  required by generally  accepted
accounting  principles  for  complete  financial  statements.  In the opinion of
management, all adjustments (consisting of normal recurring accruals) considered
necessary for a fair presentation have been included.  Operating results for the
three months ended March 31, 2003 are not necessarily  indicative of the results
that may be expected for the year ended December 31, 2003.

2.   GOING CONCERN

         The Company will continue to require  additional capital to develop its
products and develop sales and distribution channels for its products.  However,
the Company believes it lacks sufficient  working capital to fund operations for
the entire fiscal year ending December 31, 2003. Management believes there are a
number of  potential  alternatives  available to meet the  Company's  continuing
capital  requirements,  including  proceeding  as rapidly as  possible  with the
development  of  over-the-counter  products  that can be sold with a minimum  of
regulatory  compliance and developing  revenue sources through  licensing of the
Company's existing intellectual property portfolio.  In addition, the Company is
pursuing  actively  additional  debt and/or  equity  capital in order to support
ongoing  operations.  There can be no assurance that the Company will be able to
obtain sufficient additional working capital on commercially reasonable terms or
conditions, or at all.

     The  accompanying  financial  statements  have been  prepared  assuming the
Company  will  continue as a going  concern.  Continuing  as a going  concern is
dependent upon successfully  obtaining  additional  working capital as described
above.  The financial  statements do not include any  adjustments to reflect the
possible future effects on the  recoverability  and classification of assets and
amounts and classifications of liabilities that might result from the outcome of
this uncertainty.

3.   RECAPITALIZATION AND MERGER

     On April 23, 2002, Provectus Pharmaceutical, Inc., a Nevada corporation and
a "blank check" public  company,  acquired  Provectus  Pharmaceuticals,  Inc., a
privately held Tennessee  corporation  ("PPI"),  by issuing  6,680,000 shares of
common stock of Provectus  Pharmaceutical to the stockholders of PPI in exchange
for all of the  issued  and  outstanding  shares  of PPI,  as a result  of which
Provectus  Pharmaceutical  changed its name to Provectus  Pharmaceuticals,  Inc.
(the "Company") and PPI became a wholly owned subsidiary of the Company.

         For financial reporting purposes, the transaction has been reflected in
the  accompanying  financial  statements  as a  recapitalization  of PPI and the
financial statements reflect the historical financial  information of PPI, which
was incorporated on January 17, 2002.

         The  issuance  of  6,680,000   shares  of  common  stock  of  Provectus
Pharmaceutical,  Inc.  to the  stockholders  of PPI in  exchange  for all of the
issued and  outstanding  shares of PPI was done in anticipation of PPI acquiring
Valley  Pharmaceuticals,  Inc., which owned the intellectual property to be used
in the Company's operations.

4.   BASIC AND DILUTED LOSS PER COMMON SHARE

     Basic and diluted loss per common  share is computed  based on the weighted
average number of common shares outstanding.  Loss per share excludes the impact
of outstanding options, warrants, and convertible debt as they are antidilutive.
Potential  common  shares  excluded from the  calculation  at March 31, 2003 are
385,000  warrants and 1,442,984  shares  issuable upon conversion of convertible
debt and  interest.  Additionally,  the  Company is  committed  to issue  80,000
warrants.

                                       6

5.   LONG-TERM CONVERTIBLE DEBT

     On January 31, 2003, the  Convertible  Secured  Promissory Note and Warrant
Agreement  between the Company and  Gryffindor  Capital  Partners I, L.L.C.  was
amended to increase the $1,000,000 principal amount to $1,025,959.

6.   EQUITY TRANSACTIONS

     (a) In the first  quarter of 2003,  the  Company  issued  64,000  shares to
consultants  in exchange  for services  rendered.  Consulting  costs  charged to
operations were $22,800.

     (b) The  Company  applies  the  recognition  provisions  of SFAS  No.  123,
"Accounting for Stock-Based  Compensation,"  in accounting for stock options and
warrants  issued to  nonemployees.  In the first  quarter of 2003,  the  Company
issued 385,000  warrants in exchange for consulting  services  rendered.  As the
fair market value of these services was not readily determinable, these services
were valued based on the fair market value,  determined using the  Black-Scholes
option pricing model. Fair market value for warrants ranged from $0.07 to $0.24.
Consulting costs charged to operations were $19,574.  At March 31, 2003, $74,917
has been  classified  as prepaid  consulting  expense as this amount  represents
payments for services to be provided in the future.

7.   CONTINGENCIES

     On April 17, 2003, a suit was filed in the Third Judicial  District  Court,
Salt  Lake  County,   Utah  by  Kelly  Adams,  on  behalf  of  himself  and  "as
representatives of certain  stockholders of Provectus  Pharmaceuticals,  Inc., a
Nevada corporation." The suit names PPI and Michael L. Labertew,  an attorney in
Salt Lake City, Utah, as defendants, and seeks to rescind the Agreement and Plan
of  Reorganization  dated April 22, 2002 by which the Company  acquired  PPI and
PPI's former  stockholders  acquired majority  ownership of the Company's common
stock. On April 29, 2003, without giving the Company or PPI notice of the motion
or an  opportunity  to respond to it, the Utah court granted Mr.  Adams's motion
for a 10-day  temporary  restraining  order (the "TRO"),  preventing the Company
from issuing  additional shares of stock for a 10-day period commencing on April
29, 2003 and ending on May 9, 2003.

                                       7

Item 2. Management's Discussion and Analysis or Plan of Operation.

     The  following  discussion is intended to assist in the  understanding  and
assessment  of  significant  changes  and  trends  related  to  our  results  of
operations  and  our  financial   condition   together  with  our   consolidated
subsidiaries.  This discussion and analysis  should be read in conjunction  with
the consolidated  financial  statements and notes thereto included  elsewhere in
this  Quarterly  Report  on  Form  10-QSB.  Historical  results  and  percentage
relationships  set forth in the statement of operations,  including trends which
might appear, are not necessarily indicative of future operations.

OVERVIEW

History

     Provectus    Pharmaceuticals,    Inc.,   formerly   known   as   "Provectus
Pharmaceutical, Inc." and "SPM Group, Inc.," was incorporated under Colorado law
on May 1,  1978.  SPM  Group,  Inc.  ceased  operations  in 1991,  and  became a
development-stage  company  effective  January 1, 1992,  with the new  corporate
purpose  of  seeking  out  acquisitions  of  properties,  businesses,  or merger
candidates,  without  limitation as to the nature of the business  operations or
geographic location of the acquisition candidate.

     On  April  1,  2002,  SPM  Group,  Inc.  changed  its  name  to  "Provectus
Pharmaceutical,  Inc."  and  reincorporated  in  Nevada  in  preparation  for  a
transaction with Provectus  Pharmaceuticals,  Inc., a  privately-held  Tennessee
corporation  ("PPI"). On April 23, 2002, an Agreement and Plan of Reorganization
between Provectus  Pharmaceutical and PPI was approved by the written consent of
a majority of the outstanding  shares of Provectus  Pharmaceutical,  pursuant to
which  6,680,000  shares  of  common  stock  of  Provectus  Pharmaceutical  were
exchanged  for all of the issued and  outstanding  shares of PPI. As part of the
acquisition,   Provectus   Pharmaceutical   changed   its  name  to   "Provectus
Pharmaceuticals,  Inc." and PPI became a wholly owned subsidiary of the Company.
For accounting  purposes,  this transaction was treated as a recapitalization of
PPI and the  issuance of shares of PPI for  Provectus  Pharmaceutical,  Inc. The
historical  financial  information set forth in this report is PPI's  historical
financial statements from the date of PPI's incorporation, January 17, 2002.

     On  November   19,  2002,   Provectus   Pharmaceuticals   acquired   Valley
Pharmaceuticals,   Inc.  ("Valley"),   a  privately-held  Tennessee  corporation
formerly  known as Photogen,  Inc., by merging its  subsidiary PPI with and into
Valley and naming the surviving corporation "Xantech  Pharmaceuticals,  Inc." By
acquiring  Valley,  we  acquired  our  most  important   intellectual  property,
including issued U.S. patents and patentable inventions,  which we intend to use
to develop:

     o    prescription  drugs,   medical  and  other  devices  (including  laser
          devices) and over-the-counter pharmaceutical products in the fields of
          dermatology and oncology, and
     o    technologies  for  the  preparation  of  human  and  animal  vaccines,
          diagnosis  of   infectious   diseases  and  enhanced   production   of
          genetically engineered drugs.

     Prior to its  acquisition,  Valley was considered to be in the  development
stage and had not generated any revenues from the assets we acquired.

     On  December  5, 2002,  Provectus  Pharmaceuticals  acquired  the assets of
Pure-ific L.L.C., a Utah limited liability  company,  and created a wholly owned
subsidiary,  Pure-ific  Corporation,  to operate  that  business.  By  acquiring
Pure-ific  L.L.C., we acquired the product  formulations for Pure-ific  personal
sanitizing sprays, along with the "Pure-ific" trademarks. With this acquisition,
we  intend  to  continue  development  and  begin to  market a line of  personal
sanitizing  sprays and related  products  to be sold over the counter  under the
"Pure-ific" brand name.

Description Of Business

     Provectus Pharmaceuticals,  Inc., a Nevada corporation  ("Provectus"),  and
its two wholly owned subsidiaries, Xantech Pharmaceuticals, Inc. ("Xantech") and
Pure-ific  Corporation  ("Pure-ific"),  develop,  license and market and plan to
sell products in three sectors of the healthcare industry:

                                       8

     o    Over-the-counter ("OTC") products;

     o    Prescription drugs; and

     o    Medical device systems

     We manage Provectus, Xantech and Pure-ific on an integrated basis, and when
we refer  to "we" or "us" or "the  Company"  in this  Quarterly  Report  on Form
10-QSB,  we refer to all three  corporations  considered  as a single unit.  Our
principal  executive  offices  are located at 7327 Oak Ridge  Highway,  Suite A,
Knoxville, Tennessee 37931, telephone 865/769-4011.

     Through  discovery  and  use of  state-of-the-art  scientific  and  medical
technologies, the founders of our pharmaceutical business have developed a suite
of core technologies  that support multiple  products in the prescription  drug,
medical  device and OTC products  categories.  Our  prescription  drug  products
encompass  the areas of  dermatology  and oncology and involve  several types of
drugs,  including those produced by advanced  biotechnology methods. Our medical
device systems include  therapeutic and cosmetic lasers,  while our OTC products
address markets primarily involving skincare applications.

Over-the-Counter Pharmaceuticals

     Our OTC products are designed to be safer and more specific than  competing
products. Our technologies offer practical solutions for a number of intractable
maladies,  using  ingredients that have limited or no side effects compared with
existing products.

         We have developed  GloveAid,  a hand cream with both antiperspirant and
antibacterial  properties,  to increase  the comfort of users'  hands during and
after the wearing of  disposable  gloves.  Since the end of the first quarter of
2003, we have begun  small-scale  sales of GloveAid in U.S. and foreign markets,
and are focusing on reaching  full-scale  distribution of GloveAid by the fourth
quarter of 2003.

     Our Pure-ific line of products includes two quick-drying sprays,  Pure-ific
and  Pure-ific  Kids,  that  immediately  kill up to  99.9% of germs on skin and
prevent  regrowth  for 6 hours.  Pure-ific  products  help prevent the spread of
germs and thus  complement  our other OTC products  designed to treat  irritated
skin or skin conditions such as acne, eczema, dandruff and fungal infections. We
are  beginning  limited  distribution  of Pure-ific  during the first quarter of
2003.  We intend to  continue  developing  our  distribution  network  for these
products and expect to expand the Pure-ific  product line to include  additional
applications.

     A number of dermatological  conditions,  including  psoriasis,  eczema, and
acne, result from a superficial  infection which triggers an overwhelming immune
response. We anticipate developing OTC products similar to the GloveAid line for
the treatment of mild to moderate cases of psoriasis, eczema, and acne.

Prescription Drugs

     We are  developing  a number of  prescription  drugs  which we expect  will
provide minimally  invasive treatment of chronic severe skin afflictions such as
psoriasis,  eczema, and acne; and several life-threatening cancers such as those
of the liver,  breast and  prostate.  We believe that our products will be safer
and more  specific than  currently  existing  products.  Use of topical or other
direct delivery formulations allows these potent products to be conveniently and
effectively  delivered only to diseased  tissues,  thereby enhancing both safety
and  effectiveness.  All of these products are in the  pre-clinical  or clinical
trial stage.

     Our most  advanced  prescription  drug  candidate  for treatment of topical
diseases on the skin is Xantryl,  a topical gel. PV-10, the active ingredient in
Xantryl, is "photoactive": it reacts to light of certain wavelengths, increasing
its therapeutic  effects.  PV-10 also concentrates in diseased or damaged tissue
but quickly  dissipates  from healthy  tissue.  By  developing a  "photodynamic"
treatment regimen (one which combines a photoactive substance with activation by
a source emitting a particular  wavelength of light) around these two properties
of PV-10, we can deliver a higher  therapeutic effect at lower dosages of active

                                       9

ingredient,  thus minimizing  potential side effects  including damage to nearby
healthy  tissues.  PV-10  is  especially  responsive  to green  light,  which is
strongly  absorbed by the skin and thus only  penetrates  the body to a depth of
about three to five  millimeters.  For this reason,  we have  developed  Xantryl
combined with  green-light  activation  for topical use in surface  applications
where serious  damage could result if medicinal  effects were to occur in deeper
tissues.  We are researching the use of Xantryl with  green-light  activation to
treat multiple  dermatological  conditions,  including acute psoriasis,  actinic
keratosis, and severe acne.

Oncology

     Oncology is another  major  market  where our planned  products  may afford
competitive advantage compared to currently available options. We are developing
Provecta,  a sterile injectible form of PV-10, for direct injection into tumors.
Because PV-10 is retained in diseased or damaged  tissue but quickly  dissipates
from healthy tissue,  we believe we can develop therapies that confine treatment
to  cancerous  tissue and reduce  collateral  impact on healthy  tissue.  We are
researching  the use of PV-10 for the treatment of cancers of the liver,  breast
and prostate.

Medical Devices

     We are developing medical devices to address two major markets:

     o    cosmetic treatments,  such as reduction of wrinkles and elimination of
          spider veins and other cosmetic blemishes; and
     o    therapeutic   uses,   including   photoactivation   of  Xantryl  other
          prescription  drugs  and  non-surgical  destruction  of  certain  skin
          cancers.

     We expect to develop medical devices through  partnerships with third-party
device manufacturers or, if appropriate opportunities arise, through acquisition
of one or more device manufacturers.

Research and Development

     We have placed most  research  activities on hold as we attempt to conserve
available capital and achieve full  capitalization of the Company through equity
and convertible debt offerings, generation of product revenues, and other means.
In the interim,  we are maintaining our research facilities in anticipation of a
resumption  of our  research  programs.  All ongoing  research  and  development
activities  are  directed  toward   supporting  our  OTC  product  launches  and
maintaining our intellectual property portfolio.

GOING CONCERN

     In  connection  with  their  audit  report  on our  consolidated  financial
statements as of December 31, 2002, BDO Seidman LLP, our  independent  certified
public accountants, expressed substantial doubt about our ability to continue as
a going concern because such  continuance is dependent upon our ability to raise
capital or achieve profitable operations.

     Our technologies are in early stages of development.  We have not generated
revenues  from sales or operations  and we do not expect to generate  sufficient
revenues  to  enable us to be  profitable  for  several  calendar  quarters.  In
November  2002,  we  obtained $1 million  from  Gryffindor  Capital  Partners I,
L.L.C., a Delaware limited  liability company  ("Gryffindor")  through the sale,
pursuant to a Convertible Secured Promissory Note and Warrant Purchase Agreement
dated  November 26, 2002 (the  "Gryffindor  Agreement")  between the Company and
Gryffindor,  of our Convertible  Secured Promissory Note dated November 26, 2002
in the  original  principal  amount of $1 million  (the "Note") and Common Stock
Purchase  Warrants dated  November 26, 2002 (the  "Warrants").  In addition,  at
critical junctures during 2002 we obtained  approximately $109,000 in additional
funding  through  short-term  loans from Eric A. Wachter,  our Vice  President -
Pharmaceuticals,  a member of our Board of Directors,  and a major  stockholder.
These funds  allowed us to complete  our planned  corporate  reorganization  and
acquisitions,  complete initial production runs for several of our OTC products,
and maintain our  facilities and  intellectual  property  portfolio.  We require
additional  funding to  continue  initial  production  and  distribution  of OTC
products in order to achieve  meaningful  sales  volumes.  In addition,  we must
raise  substantial  additional  funds in order to fully implement our integrated
business plan, including execution of the next phases in clinical development of
our  pharmaceutical  products  and  resumption  of research  programs  currently
suspended.

     Ultimately,  we must achieve profitable operations if we are to be a viable
entity.  We intend to proceed as rapidly as possible with the development of OTC

                                       10

products that can be sold with a minimum of regulatory  compliance  and with the
development of revenue  sources through  licensing of our existing  intellectual
property portfolio. Although we believe that there is a reasonable basis for our
expectation that we will  successfully  raise the needed funds, we cannot assure
you that we will be able to  raise  sufficient  capital  to  sustain  operations
before we can commence revenue generation or that we will be able to achieve, or
maintain, a level of profitability sufficient to meet our operating expenses.

PLAN OF OPERATION

         With the  reorganization  of Provectus and PPI and the  acquisition and
integration  into the  Company  of Valley  and  Pure-ific,  we  believe  we have
obtained a unique combination of OTC products and core intellectual  properties.
This combination  represents the foundation for a successful  operating  company
that we believe will provide both short-term profitability and long-term growth.
In 2003,  through  careful  control  of  expenditures,  commencing  sales of OTC
products,  and issuance of debt and equity,  we plan to build on that foundation
to increase stockholder value.

     In the  short  term,  we intend  to  develop  our  business  by  marketing,
manufacturing,  and distributing our existing OTC products, principally GloveAid
and  Pure-ific.  In the  longer  term,  we expect to  continue  the  process  of
developing, testing and obtaining FDA approval of prescription drugs and medical
devices.  Additionally,  we intend to restart our  research  programs  that will
identify additional  conditions that our intellectual  properties may be used to
treat and additional treatments for those and other conditions.

Cash Flow

     As of March  31,  2003,  we held  approximately  $140,000  in cash.  At our
current cash expenditure  rate, this amount will be sufficient to meet our needs
until  the  middle  of  June  2003.  We have  reduced  our  expenditure  rate by
suspending most of our research programs; in addition, we are seeking to improve
our cash flow by  commencing  sales of OTC products.  However,  we cannot assure
that we will be  successful  either in  commencing  sales of OTC  products or in
reducing  expenditures.  Moreover,  even if we are  successful  in improving our
current cash flow position, we nonetheless will require additional funds to meet
our short-term and long-term needs. We anticipate these funds will come from the
proceeds of private placements or public offerings of debt or equity securities,
but we cannot assure you that we will be able to obtain such funds.

Capital Resources

     As  noted  above,  our  present  cash  flow is not  sufficient  to meet our
short-term  operating  needs for  initial  production  and  distribution  of OTC
products in order to achieve  meaningful  sales  volumes,  much less to meet our
longer-term  needs for investment in our business through  execution of the next
phases in clinical development of our pharmaceutical  products and resumption of
our currently  suspended research  programs.  We anticipate that the majority of
the funds for our  operating  and  development  needs in 2003 will come from the
proceeds of private placements or public offerings of debt or equity securities.
We are currently in discussions with multiple funding sources and feel confident
adequate operating funding and development funding will result. While we believe
that we have reasonable  basis for our expectation that we will be able to raise
additional funds, we cannot give you an assurances that we will be able to do so
on commercially  reasonable terms. In addition, any such financing may result in
significant dilution to stockholders.

Market Outlook

     Our planned products are divided into three classes:

     o    OTC products addressing the skincare markets;
     o    Prescription  pharmaceuticals  addressing the dermatology and oncology
          markets; and
     o    Medical devices

                                       11



         Our  estimates  of the size of the  markets  for  each of  these  three
planned product classes are set forth in the following table:

                                                        Approximate Annual Value
                                                         of Sales in U.S. Market
        Product Area                                           (millions)
        ------------

        OTC Products

             Personal hygiene...........................     $      100

             Disposable glove care......................            100

             Acne (all grades)..........................          1,000

        Prescription Pharmaceuticals

             Psoriasis..................................          1,500

             Liver, breast and prostate cancer..........          1,000

        Medical Devices

             Medical device systems.....................            250

Skincare

     We are developing OTC products for three areas in the skincare market:

     1. personal hygiene products;

     2. hand care products for workers who use disposable gloves; and

     3. products for treatment of acne.

     In the future,  we expect to develop  products for additional  areas in the
skincare market, including treatments for psoriasis,  eczema, and various fungal
infections such as dandruff and athlete's foot.

     Personal Hygiene.  Our Pure-ific brand of OTC products includes a number of
topical  antibacterial  products  that  address  the  personal  hygiene  market,
including a hand  sanitizer  that  immediately  kills germs on skin and prevents
regrowth for six hours. We believe that annual retail sales in the United States
of hand sanitizers are approximately $100 million; this figure excludes sales of
antibacterial  sprays  such as  Lysol(R),  which we  estimate  at more than $1.2
billion in annual U.S.  sales.  We anticipate  extending our Pure-ific  brand to
include  additional  products that leverage  technologies  utilized in our other
skincare products.

     Disposable   Glove  Care.  We  estimate  that  annual  wholesale  sales  of
disposable  gloves in the U.S. are over $1.2 billion,  including $530 million in
sales to the acute care or hospital market, $560 million in sales to the medical
laboratory  and  non-hospital  market,  and $100  million in sales to the dental
market. Use of gloves for protection in other areas, including airport security,
food preparation,  sanitation,  blood banks, research facilities, mail handling,
police and fire personnel, is rapidly growing as concerns over possible exposure
to biological or other hazards  increase.  We further  anticipate that consumers
will spend comparable amounts on hand care products as on the gloves themselves.

     Acne.  Acne affects an estimated 20 million people in the U.S. at any given
time. 85% of all people aged 12 to 25 will experience  acne problems,  while 59%
of women aged 25 to 39 suffer  from this  affliction.  70% percent of adult acne
sufferers,  and an even a higher fraction of teenagers,  rely on self-medication
to treat their acne. OTC products for treatment of mild- to moderate-grade  acne
generally are sold through  department  stores,  supermarkets,  and drug stores;
combined  sales of these  products  are believed to have  exceeded  $800 million
dollars in the year 2000 and were expected to increase by approximately  10% per
year.  In addition to these OTC products,  Frost & Sullivan  have  estimated the
U.S. prescription acne care market at $1.3 billion, with over 7.7 million visits
to physicians in 2001 for treatment of severe acne.

                                       12

         Other Skincare. We anticipate that the formulations of our OTC products
and  prescription  drugs  can be sued to treat  other  conditions  of the  skin,
including  psoriasis,  eczema,  and  fungal  infections  such  as  dandruff  and
athlete's  foot.  There are  approximately 5 million  psoriasis  patients in the
U.S.,  with over 150,000 new cases  diagnosed every year. In the U.S., the total
cost of psoriasis  treatment  was $2.9 billion in 1995.  The numbers are similar
for eczema and fungal  infections.  We believe these  represent  extremely large
future opportunities for our skincare products.

Prescription Pharmaceuticals

     We are  developing  prescription  drugs for the treatment of certain severe
dermatological  conditions  such as psoriasis,  and for the treatment of serious
cancers, including those of the liver, breast, and prostate.

     Acute   Psoriasis.   Psoriasis  is  a  chronic   skin   disease   affecting
approximately  5 million  Americans,  with  over  150,000  new  cases  diagnosed
annually. The cause of psoriasis is unknown and there is no cure. Thus, patients
typically   undergo   prolonged   care  over  a  period  of  years  to  decades.
Approximately  2.5  million  psoriasis  patients  are  treated  annually by U.S.
physicians   (primarily   dermatologists),   comprising   an  estimated   annual
expenditure  of  $1.5  billion  for  treatment  in the  mid-1990s.  More  recent
estimates  project a $1-2 billion market  opportunity for new therapies  divided
among several multi-hundred-million dollar products.

     Liver Cancer.  Hepatocellular carcinoma, or HCC, accounts for approximately
90% of all liver  tumors and is the most  common  solid-organ  tumor  worldwide,
causing over 1 million  deaths  annually.  HCC is associated  with chronic liver
injury  from viral  hepatitis  (hepatitis  B and C), and has  attained  epidemic
proportions  among  men aged 25 to 34 in  eastern  Asia,  tropical  Africa,  and
southern Italy.  Although  currently of relatively low incidence in the U.S. and
Europe,  the rapid rise in hepatitis  infection in these regions  signifies that
this may soon change. In contrast,  the primary form of liver cancer in the U.S.
currently  is  metastatic  colorectal  carcinoma  (155,000  new cases and 60,000
deaths  annually,  with a 6% five-year  survival rate).  The current standard of
care for these forms of liver cancer is ablative therapy (via localized  ethanol
injection,  cryosurgery,  or  radiofrequency  ablation).  A  combined  five-year
survival rate of 33% for these therapies  demonstrates the pressing need for new
therapeutic approaches in a worldwide market estimated at over $500 million.

     Breast Cancer.  The American  Cancer Society  estimates that  approximately
205,000 new cases of  invasive  breast  cancer,  and over 54,000 new cases of in
situ breast  cancer,  will occur in the U.S. in 2002,  leading to  approximately
40,000 deaths. Current treatments (lumpectomy,  mastectomy,  removal of regional
lymph nodes, radiation therapy, chemotherapy, and hormone therapy) are expensive
and associated with  unacceptable side effects.  While five-year  survival rates
are excellent for  localized  tumors (96%),  this rate drops to 21% once distant
metastasis has occurred.  This illustrates  that surgical  excision and standard
adjuvant  treatments  (such as  chemotherapy  and radiation) are  ineffective at
eliminating metastatic cells that have migrated from the primary treatment site.
New,  minimally-invasive  treatment  modalities for breast cancer may have broad
applicability to this therapeutic market estimated at well over $1 billion.

     Prostate Cancer.  The American Cancer Society estimates that  approximately
190,000 U.S. men are afflicted annually with cancer of the prostate,  leading to
over 30,000 deaths.  As with breast cancer,  surgical  resection,  chemotherapy,
radiation therapy,  and immunotherapy  comprise the standard  treatments for the
majority of cases, and can result in serious, permanent side effects. We believe
that  new,  minimally-invasive  modalities  - such as  direct  injection  of our
prescription  drug Provecta into prostate tumors - may have broad  applicability
to this therapeutic market as an adjuvant or primary form of therapy,  providing
an entry into a therapeutic market estimated at well over $500 million.

Medical Device Systems

     This  market area  comprises  two  sectors:  cosmetic  treatments,  such as
non-ablative  wrinkle reduction,  elimination of spider veins and other cosmetic
blemishes,  and laser hair reduction; and therapeutic uses, including activation
of certain of the  Company's  light-activated  drugs.  Additional  areas include

                                       13

non-surgical destruction of skin cancers and removal of unwanted moles and other
hyperpigmented  features. The U.S. medical laser market exceeded $1.6 billion in
2000, while the market for wrinkle reduction and hair reduction systems alone is
currently in excess of $100 million annually. We believe that we can develop new
markets for laser devices,  significantly  in addition to the current market for
these  devices,  as a result  of the  development  of  therapies  consisting  of
photoactivation of the our prescription drug products.

FORWARD-LOOKING STATEMENTS

     This Quarterly  Report on Form 10-QSB contains  forward-looking  statements
regarding,  among other things, our anticipated financial and operating results.
Forward-looking   statements  reflect  our  management's   current  assumptions,
beliefs,  and expectations.  Words such as "anticipate,"  "believe,  "estimate,"
"expect,"  "intend,"  "plan," and similar  expressions  are intended to identify
forward-looking statements.  While we believe that the expectations reflected in
our  forward-looking  statements are  reasonable,  we can give no assurance that
such expectations will prove correct.  Forward-looking statements are subject to
risks and uncertainties that could cause our actual results to differ materially
from the future results, performance, or achievements expressed in or implied by
any  forward-looking   statement  we  make.  Some  of  the  relevant  risks  and
uncertainties  that could cause our actual performance to differ materially from
the forward-looking  statements contained in this report are discussed under the
heading "Risk Factors" and elsewhere in our Annual Report on Form 10-KSB,  which
was filed  with the SEC on April 15,  2003.  We  caution  investors  that  these
discussions of important  risks and  uncertainties  are not  exclusive,  and our
business may be subject to other risks and uncertainties  which are not detailed
there.

     Investors are cautioned not to place undue reliance on our  forward-looking
statements.  We make  forward-looking  statements  as of the date on which  this
Quarterly  Report  on Form  10-QSB  is  filed  with the SEC,  and we  assume  no
obligation  to update  the  forward-looking  statements  after  the date  hereof
whether as a result of new  information  or events,  changed  circumstances,  or
otherwise, except as required by law.

Item 3. Controls and Procedures.

(a)  Evaluation  of  Disclosure  Controls and  Procedures.  Our chief  executive
     officer and chief financial officer have evaluated the effectiveness of the
     design and operation of our  "disclosure  controls and procedures" (as that
     term is  defined in Rule  13a-14(c)  under the  Exchange  Act) as of a date
     within 90 days of the filing date of this Quarterly  Report on Form 10-QSB.
     Based on that evaluation,  the chief executive  officer and chief financial
     officer have  concluded  that our  disclosure  controls and  procedures are
     effective to ensure that material  information  relating to the Company and
     the Company's  consolidated  subsidiaries is made known to such officers by
     others within these entities, particularly during the period this Quarterly
     Report on Form  10-QSB was  prepared,  in order to allow  timely  decisions
     regarding required disclosure.

(b)  Changes in Internal Controls.  There have not been any significant  changes
     in our  internal  controls  or in other  factors  that could  significantly
     affect these controls subsequent to the date of their evaluation.


                                       14



                                     Part II
                                Other Information

Item 1. Legal Proceedings.

     On April 17, 2003,  subsequent to the end of the fiscal quarter  covered by
this  Quarterly  Report on Form  10-QSB  but prior to the date on which we filed
this report with the Securities and Exchange Commission, a suit was filed in the
Third Judicial District Court, Salt Lake County,  Utah by Kelly Adams, on behalf
of  himself  and  "as  representative  of  certain   Stockholders  of  Provectus
Pharmaceuticals,  Inc., a Nevada corporation." The suit names PPI and Michael L.
Labertew,  an  attorney in Salt Lake City,  Utah,  as  defendants,  and seeks to
rescind the Agreement and Plan of  Reorganization  dated April 22, 2002 by which
we acquired PPI and PPI's former stockholders acquired majority ownership of our
common  stock.  (This  transaction  is  discussed in more detail in Part I above
under  the   heading   "Management's   Discussion   and   Analysis  or  Plan  of
Operation.-Overview-History.")  On April 29, 2003, without giving the Company or
PPI  notice of the  motion or an  opportunity  to  respond to it, the Utah court
granted Mr. Adams's motion for a 10-day temporary restraining order (the "TRO"),
preventing  us from  issuing  additional  shares  of stock  for a 10-day  period
commencing on April 29, 2003 and ending on May 9, 2003. Mr. Adams also has moved
for a preliminary  injunction that would impose the same restrictions  until the
completion  of the  proceedings.  The Utah court has  scheduled a hearing on the
motion for May 13,  2003,  at which the court will  determine  whether or not to
issue the requested preliminary injunction.

     We believe the TRO was issued without reason or due process, and we believe
that the  claims  made by Mr.  Adams  and the  "certain  Stockholders"  in their
complaint are  groundless.  We have retained  counsel in Utah,  and we intend to
contest vigorously the motion for a preliminary  injunction and the remainder of
the suit.

Item 2. Changes in Securities and Use of Proceeds.


Recent Sales of Unregistered Securities

     During  the  three  months  ended  March  31,  2003,  we did not  sell  any
securities  which  were not  registered  under the  Securities  Act of 1933,  as
amended (the "Securities Act") except as follows:

     1.   Pursuant  to a letter  agreement  dated  January 8, 2003  between  the
          Company and Investor-Gate.com ("Investor-Gate"),  the Company retained
          Investor-Gate  to  provide  investor  relations  services.  For  these
          services,  the Company  agreed to pay  Investor-Gate  a monthly fee of
          $7,250 for the first three months of the  agreement  and a monthly fee
          of $6,000 per month  thereafter.  The  monthly fee for the first three
          months was paid by the  issuance  and  delivery  to  Investor-Gate  of
          29,000 shares of our common stock at an agreed-upon value of $0.75 per
          share. In addition, we agreed to grant Investor-Gate  warrants for the
          purchase of additional  shares of our common stock. As of the close of
          business on January 8, 2003,  the value of our common  stock was $0.40
          per share.

          On February 28, 2003, we terminated the agreement  with  Investor-Gate
          as a result of  Investor-Gate's  failure to perform the contracted-for
          investor relations services.  Investor-Gate retained the 29,000 shares
          initially  issued  to it,  as well as a  warrant  exercisable  for the
          purchase of 25,000 shares of our common stock at an exercise  price of
          $0.75  per  share.  In  addition,   we  remained  obligated  to  issue
          additional warrants to Investor-Gate on the following terms:

     Number of Shares    Exercise Price     Issue Date         Termination Date
     ----------------    --------------     ----------         ----------------
     25,000 shares           $2.00         April 8, 2003      September 8, 2004

     25,000 shares           $5.00        January 8, 2004        July 8, 2005

          We relied on an exemption from  registration  pursuant to Section 4(2)
          of the  Securities  Act, based on the sale of the shares and warrants,
          and the issuance of the shares of common stock  issuable upon exercise
          of the warrants,  to a single purchaser in a transaction not involving
          any general solicitation or general advertising.

                                       15

     2.   Pursuant to a letter  agreement  dated  January  31, 2003  between the
          Company and Gryffindor,  the Company issued  Gryffindor an Amended and
          Restated Senior Secured Convertible Note dated January 31, 2003 in the
          original  principal  amount of $1,025,959  (the "Amended  Note").  The
          Amended  Note bears  interest at 8% per annum,  payable  quarterly  in
          arrears,  is due and payable in full on November 26, 2004,  and amends
          and restated the original Note in its entirety.  As with the Note, our
          obligations  under the Amended  Note are  secured by a first  priority
          security interest in all of our Company's assets, including the assets
          held by our Xantech  and  Pure-ific  subsidiaries.  Subject to certain
          exceptions,  the Amended Note is convertible into shares of our common
          stock beginning on the November 26, 2003; the principal  amount of the
          Note is  convertible at the rate of one share of common stock for each
          $0.73655655 of principal converted,  while accrued but unpaid interest
          on the Note is  convertible  at the rate of one share of common  stock
          for each $0.55 of accrued but unpaid interest converted.  We relied on
          an  exemption  from  registration  pursuant  to  Section  4(2)  of the
          Securities  Act,  based on the issuance of the Amended  Note,  and the
          issuance of the shares of common stock issuable upon conversion of the
          Amended Note, to a limited  number of purchasers in a transaction  not
          involving any general solicitation or general advertising.

     3.   Pursuant to a letter  agreement  dated  February  20, 2003 between the
          Company and Strategic Growth International,  Inc. ("SGI"), the Company
          retained SGI as its investor relations consultant.  For services under
          the Agreement, the Company issued SGI warrants on the following terms:

      Number of Shares   Exercise Price     Issue Date        Termination Date
      ----------------   --------------     ----------        ----------------
      120,000 shares         $0.25       February 20, 2003   February 20, 2008

      120,000 shares         $0.35       February 20, 2003   February 20, 2008

      120,000 shares         $0.50       February 20, 2003   February 20, 2008

          In addition, at the Company's option, during the first three months of
          the  agreement  the Company  may elect to issue SGI 30,000  shares per
          month in lieu of payment  of $3,000 of the  monthly  cash fee  payable
          under the  agreement.  As of the close of business on February 18, the
          last day on which a trade was reported  prior to the  execution of the
          agreement with SGI, the value of our common stock was $0.26 per share.
          During the  quarter  ended March 31,  2003,  we did not  exercise  our
          option to issue  shares in lieu of  payment  of fees.  We relied on an
          exemption from registration pursuant to Section 4(2) of the Securities
          Act, based on the sale of the shares and warrants, and the issuance of
          the shares of common stock issuable upon exercise of the warrants,  to
          a  single  purchaser  in  a  transaction  not  involving  any  general
          solicitation or general advertising.

     4.   Pursuant  to a letter  agreement  dated  March 27,  2003  between  the
          Company and Josephberg Grosz & Co., Inc.  ("JGC"),  the Company issued
          JG Capital,  Inc., an affiliate of JGC,  35,000 shares of common stock
          as  consideration  for  JGC's  agreement  to  assist  the  Company  in
          obtaining additional capital. As of the close of business on March 21,
          2003,  the  last  day on  which  a trade  was  reported  prior  to the
          execution of the agreement with JGC, the value of our common stock was
          $0.32 per share. We relied on an exemption from registration  pursuant
          to  Section  4(2) of the  Securities  Act,  based on the sale of these
          shares  to a single  purchaser  in a  transaction  not  involving  any
          general solicitation or general advertising.

Item 3. Defaults Upon Senior Securities.

          No response is required to this item.

Item 4.  Submission of Matters to a Vote of Security Holders.

     During the three months ended March 31, 2003, we did not submit any matters
to a vote of our stockholders.

                                       16

Item 5.  Other Information.

     There are no new matters to report.

Item 6. Exhibits and Reports on Form 8-K.

(a)  Exhibits.  Exhibits required by Item 601 of Regulation S-B are incorporated
     herein by reference  and are listed on the attached  Exhibit  Index,  which
     begins on page X-1 of this Quarterly Report on Form 10-QSB.

(b)  Reports on Form 8-K.  During the fiscal  quarter  ended March 31, 2003,  we
     filed the following Current Reports on Form 8-K:

     1.   On January 3, 2003 we filed,  and on  January  9, 2003 we  amended,  a
          Current  Report on Form 8-K  reporting  that on  December  20, 2002 we
          engaged BDO  Seidman,  LLP to audit our books and records for 2002 and
          dismissed Bierwolf,  Nilson & Associates,  formerly Crouch, Bierwolf &
          Associates, as our independent auditors.

                                       17

                                   Signatures

     In accordance  with Section 13 or 15(d) of the Exchange Act, the Registrant
caused this report to be signed on its behalf by the undersigned, thereunto duly
authorized.

                                         Provectus Pharmaceuticals, Inc.


                                         By: /s/H. Craig Dees
                                             ----------------------------
                                             H. Craig Dees, Ph.D.
                                             Chief Executive Officer

Date:    May 9, 2003

                                       18


                    Certification of Chief Executive Officer

I, H. Craig Dees, Ph.D., certify that:

     1.   I have  reviewed  this  quarterly  report on Form 10-QSB of  Provectus
          Pharmaceuticals, Inc.;

     2.   Based on my  knowledge,  this  quarterly  report  does not contain any
          untrue  statement of a material  fact or omit to state a material fact
          necessary to make the statements  made, in light of the  circumstances
          under which such  statements were made, not misleading with respect to
          the period covered by this quarterly report; and

     3.   Based on my knowledge,  the financial statements,  and other financial
          information  included in this quarterly report,  fairly present in all
          material respects the financial  condition,  results of operations and
          cash flows of  Provectus  Pharmaceuticals,  Inc.  as of, and for,  the
          periods presented in this quarterly report.

     4.   The registrant's  other certifying  officers and I are responsible for
          establishing  and maintaining  disclosure  controls and procedures (as
          defined in Exchange  Act Rules  13a-14 and 15d-14) for the  registrant
          and have:

          a.   designed such  disclosure  controls and procedures to ensure that
               material  information  relating to the registrant,  including its
               consolidated  subsidiaries,  is made known to us by others within
               those  entities,  particularly  during  the  period in which this
               quarterly report is being prepared;

          b.   evaluated  the  effectiveness  of  the  registrant's   disclosure
               controls and  procedures as of a date within 90 days prior to the
               filing date of this quarterly report (the "Evaluation Date"); and

          c.   presented  in this  quarterly  report our  conclusions  about the
               effectiveness of the disclosure  controls and procedures based on
               our evaluation as of the Evaluation Date;

     5.   The registrant's other certifying officers and I have disclosed, based
          on our most recent  evaluation,  to the registrant's  auditors and the
          audit  committee  of  registrant's  board  of  directors  (or  persons
          performing the equivalent functions):

          a.   all  significant  deficiencies  in the  design  or  operation  of
               internal  controls which could adversely  affect the registrant's
               ability to record,  process,  summarize and report financial data
               and have  identified for the  registrant's  auditors any material
               weaknesses in internal controls; and

          b.   any fraud,  whether or not material,  that involves management or
               other employees who have a significant  role in the  registrant's
               internal controls; and

     6.   The  registrant's  other  certifying  officers and I have indicated in
          this  quarterly  report  whether  there  were  significant  changes in
          internal controls or in other factors that could significantly  affect
          internal   controls   subsequent  to  the  date  of  our  most  recent
          evaluation,   including   any   corrective   actions  with  regard  to
          significant deficiencies and material weaknesses.

Date:    May 9, 2003                             /s/Craig Dees
                                                 ------------------------------
                                                 H.   Craig   Dees, Ph.D.
                                                 Chairman of the Board and
                                                 Chief Executive Officer


                                       19


                    Certification of Chief Financial Officer

I, Daniel R. Hamilton, certify that:

     1.   I have  reviewed  this  quarterly  report on Form 10-QSB of  Provectus
          Pharmaceuticals, Inc.;

     2.   Based on my  knowledge,  this  quarterly  report  does not contain any
          untrue  statement of a material  fact or omit to state a material fact
          necessary to make the statements  made, in light of the  circumstances
          under which such  statements were made, not misleading with respect to
          the period covered by this quarterly report; and

     3.   Based on my knowledge,  the financial statements,  and other financial
          information  included in this quarterly report,  fairly present in all
          material respects the financial  condition,  results of operations and
          cash flows of  Provectus  Pharmaceuticals,  Inc.  as of, and for,  the
          periods presented in this quarterly report.

     4.   The registrant's  other certifying  officers and I are responsible for
          establishing  and maintaining  disclosure  controls and procedures (as
          defined in Exchange  Act Rules  13a-14 and 15d-14) for the  registrant
          and have:

          a.   designed such  disclosure  controls and procedures to ensure that
               material  information  relating to the registrant,  including its
               consolidated  subsidiaries,  is made known to us by others within
               those  entities,  particularly  during  the  period in which this
               quarterly report is being prepared;

          b.   evaluated  the  effectiveness  of  the  registrant's   disclosure
               controls and  procedures as of a date within 90 days prior to the
               filing date of this quarterly report (the "Evaluation Date"); and

          c.   presented  in this  quarterly  report our  conclusions  about the
               effectiveness of the disclosure  controls and procedures based on
               our evaluation as of the Evaluation Date;

     5.   The registrant's other certifying officers and I have disclosed, based
          on our most recent  evaluation,  to the registrant's  auditors and the
          audit  committee  of  registrant's  board  of  directors  (or  persons
          performing the equivalent functions):

          a.   all  significant  deficiencies  in the  design  or  operation  of
               internal  controls which could adversely  affect the registrant's
               ability to record,  process,  summarize and report financial data
               and have  identified for the  registrant's  auditors any material
               weaknesses in internal controls; and

          b.   any fraud,  whether or not material,  that involves management or
               other employees who have a significant  role in the  registrant's
               internal controls; and

     6.   The  registrant's  other  certifying  officers and I have indicated in
          this  quarterly  report  whether  there  were  significant  changes in
          internal controls or in other factors that could significantly  affect
          internal   controls   subsequent  to  the  date  of  our  most  recent
          evaluation,   including   any   corrective   actions  with  regard  to
          significant deficiencies and material weaknesses.

Date:    May 9, 2003                                 /s/Daniel R. Hamilton
                                                     -----------------------
                                                     Daniel R. Hamilton
                                                     Chief Financial Officer

                                       20

                                  Exhibit Index

 Exhibit No.                        Description

    3.1.1      Articles of  Incorporation  of  Provectus  Pharmaceuticals,  Inc.
               ("Provectus"),  incorporated herein by reference to Exhibit 3.i.2
               to the Company's Annual Report on Form 10-KSB for the fiscal year
               ended December 31, 2001, as filed with the SEC on April 17, 2002.

    3.1.2      Articles  of  Merger  of  Provectus   Pharmaceuticals,   Inc.,  a
               Colorado  corporation,  with  and  into  Provectus,  incorporated
               herein by  reference  to Exhibit  3.i.3 to the  Company's  Annual
               Report on Form  10-KSB for the fiscal  year  ended  December  31,
               2001, as filed with the SEC on April 17, 2002.

    3.1.3      Certificate  of  Amendment  of  Articles  of   Incorporation   of
               Provectus,  incorporated  herein by reference to Exhibit 3.1.3 to
               the  Company's  Annual  Report on Form 10-KSB for the fiscal year
               ended December 31, 2002, as filed with the SEC on April 15, 2003.

      3.2+     Bylaws of Provectus Pharmaceuticals, Inc. (the "Company")

    4.2.1*     Convertible  Secured  Promissory  Note  and  Warrant  Purchase
               Agreement  dated as of November  26, 2002 between the Company and
               Gryffindor    Capital   Partners   I,   L.L.C.    ("Gryffindor"),
               incorporated  herein by reference to Exhibit 4.1 to the Company's
               Current Report on Form 8-K dated November 26, 2002, as filed with
               the SEC on December 10, 2002.

    4.2.2+     Letter Agreement dated January 31, 2003 between the Company and
               Gryffindor.

      4.3+     Amended and Restated  Convertible  Secured Promissory Note of the
               Company dated January 31, 2003, issued to Gryffindor.

      4.6*     Stock Pledge  Agreement dated as of November 26, 2002 between the
               Company  and  Gryffindor,  incorporated  herein by  reference  to
               Exhibit  4.5 to the  Company's  Current  Report on Form 8-K dated
               November 26, 2002, as filed with the SEC on December 10, 2002.

      4.7      Guaranty  dated  November 26, 2002 from Xantech  Pharmaceuticals,
               Inc., a Tennessee  corporation  and a wholly owned  subsidiary of
               Provectus  ("Xantech"),  to  Gryffindor,  incorporated  herein by
               reference to Exhibit 4.6 to the Company's  Current Report on Form
               8-K dated  November 26,  2002,  as filed with the SEC on December
               10, 2002.

      4.8      Form of Security  Agreement  between the Company and  Gryffindor,
               incorporated  herein by reference to Exhibit 4.7 to the Company's
               Current Report on Form 8-K dated November 26, 2002, as filed with
               the SEC on December 10, 2002.

      4.9      Form of Patent and License Security Agreement between the Company
               and Gryffindor,  incorporated  herein by reference to Exhibit 4.8
               to the Company's  Current  Report on Form 8-K dated  November 26,
               2002, as filed with the SEC on December 10, 2002.

     4.10      Form of Trademark  Collateral  Assignment and Security  Agreement
               between  the  Company  and  Gryffindor,  incorporated  herein  by
               reference to Exhibit 4.9 to the Company's  Current Report on Form
               8-K dated  November 26,  2002,  as filed with the SEC on December
               10, 2002.

     4.11      Form of  Copyright  Security  Agreement  between  the Company and
               Gryffindor,  incorporated  herein by reference to Exhibit 4.10 to
               the Company's Current Report on Form 8-K dated November 26, 2002,
               as filed with the SEC on December 10, 2002.

     4.17*+    Common Share Purchase Warrant dated January 29, 2003, issued to
               Investor-Gate.com ("Investor-Gate").

  10.11.1+     Letter  Agreement  dated  January 8, 2003 between the Company
               and Investor-Gate.

                                      X-1

  10.11.2+     Termination  Letter dated February 28, 2003 from the Company
               to Investor-Gate.

    10.12+     Letter  Agreement  dated  February 20, 2003 between the Company
               and SGI.

    10.13+     Letter  Agreement  dated March 27, 2003 between the Company and
               Josephberg Grosz & Co., Inc.

     16.1      Letter of Bierwolf  Nilson &  Associates  dated  January 8, 2003,
               pursuant to Item 304(a)(3) of Regulation S-B, regarding change of
               certifying  accountant,   incorporated  herein  by  reference  to
               Exhibit 16.1 to the  Company's  Current  Report on Form 8-K dated
               December 20, 2003.

     99.1+     Certification  Pursuant to 18 U.S.C.ss.  1350 (enacted by Section
               906 of the Sarbanes-Oxley Act of 2002, Public Law 107-204), dated
               May 9, 2003,  executed by H. Craig Dees,  Ph.D.,  Chief Executive
               Officer of the Company,  and Daniel R. Hamilton,  Chief Financial
               Officer of the Company.

 ------------------------------------
      *       The Company agrees by this filing to supplementally furnish to the
              SEC, upon request, a copy of the exhibits and/or schedules to this
              agreement.

     **       Management compensation contract or plan.

      +       Filed herewith.


                                      X-2



                                                                     Exhibit 3.2
                                     Bylaws
                                       of
                         Provectus Pharmaceuticals, Inc.
--------------------------------------------------------------------------------

                                   Article I
                                  STOCKHOLDERS

Section 1.1.      Annual Meetings

     An  annual  meeting  of  stockholders  shall  be held for the  election  of
directors  at such  date as may be  designated  by  resolution  of the  Board of
Directors from time to time. Any other proper  business may be transacted at the
annual meeting.

Section 1.2.      Special Meetings

     Special  meetings of stockholders for any purpose or purposes may be called
at any time by the  Board of  Directors,  or by a  committee  that has been duly
designated  by the Board of  Directors  and has the power and  authority to call
such meetings,  but such special  meetings may not be called by any other person
or persons.

Section 1.3.      Time and Place of Meetings

     All meetings of stockholders shall be held at such time and place,  whether
within or without the State of Nevada,  as determined by the Board of Directors.
If authorized by the Board of Directors in its sole  discretion,  and subject to
such guidelines and procedures as the Board of Directors may adopt, stockholders
and  proxyholders  not physically  present at a meeting of stockholders  may, by
means of remote communication: (a) participate in a meeting of stockholders; and
(b) be deemed  present  and in  person  and vote at a  meeting  of  stockholders
whether such  meeting is to be held at a designated  place or solely by means of
remote  communication;  provided,  that  (i)  the  Corporation  shall  implement
reasonable  measures to verify that each person deemed  present and permitted to
vote at the  meeting  by means  of  remote  communication  is a  stockholder  or
proxyholder;  (ii) the  Corporation  shall  implement  measures to provide  such
stockholders a reasonable  opportunity to participate in the meeting and to vote
on matters  submitted to the  stockholders,  including an opportunity to read or
hear  the  proceedings  of the  meeting  substantially  concurrently  with  such
proceedings,  and (iii) if any  stockholder or proxyholder  votes or takes other
action at the meeting by means of remote communication, a record of such vote or
other action shall be maintained by the Corporation.

Section 1.4.      Notice of Meetings

     (a) Whenever stockholders are required or permitted to take any action at a
meeting,  a written  notice of the meeting  shall be given which shall state the
place, if any, date and hour of the meeting, the means of remote communications,
if any, by which  stockholders  and  proxyholders may be deemed to be present in
person and vote at such  meeting,  and,  in the case of a special  meeting,  the
purpose or purposes for which the meeting is called.  Unless otherwise  provided
by law,  the written  notice of any meeting  shall be given not less than 10 nor
more than 60 days before the date of the meeting to each stockholder entitled to
vote at such  meeting.  If mailed,  such notice shall be deemed to be given when
deposited in the mail,  postage  prepaid,  directed to the stockholder at his or
her address as it appears on the records of the Corporation.

     (b) Without  limiting  the manner by which  notice  otherwise  may be given
effectively to stockholders, any notice to stockholders given by the Corporation
shall be effective if given by a form of electronic transmission consented to by
the stockholder to whom the notice is given. Any such consent shall be revocable
by the stockholder by written notice to the Corporation.  Any such consent shall
be deemed  revoked if (i) the  Corporation  is unable to  deliver by  electronic
transmission two consecutive notices given by the Corporation in accordance with
such  consent  and (ii) such  inability  becomes  known to the  secretary  or an
assistant secretary of the Corporation or to the transfer agent, or other person
responsible for the giving of notice; provided, however, the inadvertent failure
to treat such  inability as a  revocation  shall not  invalidate  any meeting or
other action.

                                       1

     (c) Notice given pursuant to Section  1.4(b) shall be deemed given:  (i) if
by  facsimile  telecommunication,  when  directed  to  a  number  at  which  the
stockholder  has consented to receive notice;  (ii) if by electronic  mail, when
directed to an electronic mail address at which the stockholder has consented to
receive  notice;  (iii) if by a posting on an electronic  network  together with
separate notice to the stockholder of such specific  posting,  upon the later of
(A) such posting and (B) the giving of such separate notice;  and (iv) if by any
other form of  electronic  transmission,  when directed to the  stockholder.  An
affidavit of the secretary or an assistant secretary or of the transfer agent or
other  agent of the  Corporation  that the  notice  has been  given by a form of
electronic  transmission shall, in the absence of fraud, be prima facie evidence
of the facts stated therein.

Section 1.5.      Adjournments

     Any meeting of  stockholders,  annual or special,  may adjourn from time to
time to reconvene at the same or some other place,  and notice need not be given
of any such adjourned meeting if the time, place, if any, thereof, and the means
of remote  communication,  if any, by which stockholders and proxyholders may be
deemed to be present in person and vote at such adjourned  meeting are announced
at the meeting at which the adjournment is taken.  At the adjourned  meeting the
Corporation  may transact any business  which might have been  transacted at the
original  meeting.  If the adjournment is for more than 30 days, or if after the
adjournment  a new record date is fixed for the adjourned  meeting,  a notice of
the adjourned  meeting shall be given to each  stockholder of record entitled to
vote at the meeting.

Section 1.6.      Quorum

     At each meeting of stockholders,  except where otherwise provided by law or
the Articles of Incorporation or these Bylaws,  the holders of a majority of the
outstanding  shares of stock entitled to vote at the meeting,  present in person
or by  proxy,  shall  constitute  a quorum.  In the  absence  of a  quorum,  the
stockholders so present may, by majority vote,  adjourn the meeting from time to
time in the manner  provided in Section 1.5 of these Bylaws until a quorum shall
attend.  Shares of its own stock  belonging  to the  Corporation  or to  another
corporation,  if a majority of the shares  entitled  to vote in the  election of
directors of such other  corporation  is held,  directly or  indirectly,  by the
Corporation,  shall  neither  be  entitled  to vote nor be  counted  for  quorum
purposes; provided, however, that the foregoing shall not limit the right of any
corporation to vote stock,  including but not limited to its own stock,  held by
it in a fiduciary capacity.

Section 1.7.      Administration of Meetings

     Meetings  of  stockholders  shall be presided  over by the  Chairman of the
Board,  if any, or in his or her absence by the Vice  Chairman of the Board,  if
any,  or in his or her absence by the  President,  or in his or her absence by a
Vice  President,  or in the  absence  of the  foregoing  persons,  by a chairman
designated by the Board of Directors, or in the absence of such designation,  by
a chairman  chosen at the meeting.  The Secretary  shall act as secretary of the
meeting,  but in his or her absence the  chairman of the meeting may appoint any
person to act as secretary of the meeting.

Section 1.8.      Voting; Proxies

     Except  as  otherwise  provided  by the  Articles  of  Incorporation,  each
stockholder entitled to vote at any meeting of stockholders shall be entitled to
one vote for each  share of stock  held by him which has  voting  power upon the
matter  in  question.  Each  stockholder  entitled  to  vote  at  a  meeting  of
stockholders  may authorize  another  person or persons to act for him by proxy,
but no such proxy  shall be voted or acted upon after three years from its date,
unless the proxy  provides for a longer  period.  A duly executed proxy shall be
irrevocable if it states that it is irrevocable  and if, and only as long as, it
is coupled with an interest sufficient in law to support an irrevocable power. A
stockholder  may revoke any proxy  which is not  irrevocable  by  attending  the
meeting and voting in person or by filing an instrument in writing  revoking the
proxy or another duly executed  proxy bearing a later date with the Secretary of

                                       2

the  Corporation.  Voting at  meetings  of  stockholders  need not be by written
ballot and need not be conducted by inspectors unless the Board of Directors, or
holders of a majority of the outstanding shares of all classes of stock entitled
to vote  thereon  present  in  person  or by  proxy  at such  meeting  shall  so
determine.  If voting at a meeting  of  stockholders  is  conducted  by  written
ballot, such ballots may be transmitted  electronically,  provided that any such
electronic  transmission  must either set forth or be submitted with information
from which in can be determined that the electronic  transmission was authorized
by the  stockholder  or  proxyholder.  At all meetings of  stockholders  for the
election  of  directors  a plurality  of the votes cast shall be  sufficient  to
elect. All other elections and questions shall, unless otherwise provided by law
or by the Articles of Incorporation  or these Bylaws,  be decided by the vote of
the holders of a majority of the  outstanding  shares of stock  entitled to vote
thereon present in person or by proxy at the meeting.

Section 1.9.      Fixing Date for Determination of Stockholders of Record

     For the purpose of determining the  stockholders  entitled to notice of, or
to vote at any meeting of stockholders or any adjournment thereof, or to express
consent to or dissent from any proposal without a meeting,  or to receive notice
that any such corporate action was taken without a meeting or for the purpose of
determining the stockholders  entitled to receive payment of any dividend or the
allotment of any rights,  or to exercise any rights in respect of any conversion
or exchange of stock or for the purpose of any other lawful action affecting the
interests of stockholders, the Board of Directors may fix, in advance, a date as
the record date for any such  determination of stockholders.  Such date shall be
not be more than 60 nor less than 10 days  before  the date of any such  meeting
nor more than 60 days before any such other actions. If no record date is fixed,
(a) the record date for determining the stockholders entitled to notice of or to
vote at a meeting  shall be at the close of business  on the day next  preceding
the date on which  notice is given,  or, if no notice is given,  on the day next
preceding  the day on  which  the  meeting  is  held;  (b) the  record  date for
determining the  stockholders  entitled to express written consent to the taking
of any corporate action without a meeting,  when no prior action by the Board of
Directors is necessary,  shall be the day on which the first written  consent is
expressed;  and (c) the record date for determining stockholders for any purpose
other than those  specified  in (a) and (b) above shall be the close of business
on the day on which the resolution of the Board of Directors relating thereto is
adopted.

Section 1.10.     List of Stockholders Entitled to Vote

     The Secretary shall prepare and make, at least 10 days before every meeting
of  stockholders,  a complete list of the  stockholders  entitled to vote at the
meeting,  arranged  in  alphabetical  order,  and  showing  the  address of each
stockholder and the number of shares registered in the name of each stockholder.
The  Corporation  shall not be required to include  electronic mail addresses or
other  electronic  contact  information on such list. Such list shall be open to
the examination of any stockholder, for any purpose germane to the meeting for a
period of at least 10 days  prior to the  meeting,  either  (a) on a  reasonably
accessible  electronic network,  provided that the information  required to gain
access to such list is provided  with the notice of the  meeting,  or (b) during
ordinary  business hours, at the principal place of business of the Corporation.
In the event that the  Corporation  determines to make the list  available on an
electronic  network,  the Corporation  may take reasonable  steps to ensure that
such  information is available only to stockholders of the  Corporation.  If the
meeting is to be held at a place,  then the list shall be  produced  and kept at
the time and place of the  meeting  during  the whole time  thereof,  and may be
inspected by any stockholder who is present. If the meeting is to be held solely
by means of  remote  communication,  then  the  list  shall  also be open to the
examination  of any  stockholder  during  the  whole  time of the  meeting  on a
reasonably accessible electronic network, and the information required to access
such list shall be provided  with the notice of the  meeting.  The stock  ledger
shall be the only  evidence as to who are the  stockholders  entitled to examine
the stock ledger,  the list of stockholders or the books of the Corporation,  or
to vote in person or by proxy at any meeting of stockholders.

Section 1.11.     Action by Consent of Stockholders

     (a) Unless  otherwise  restricted  by the  Articles of  Incorporation,  any
action required or permitted to be taken at any annual or special meeting of the
stockholders may be taken without a meeting,  without prior notice and without a
vote,  if a consent in  writing,  setting  forth the  action so taken,  shall be
signed by the  holders of  outstanding  stock  having not less than the  minimum
number of votes that would be  necessary  to  authorize or take such action at a
meeting at which all shares  entitled to vote  thereon  were  present and voted.
Prompt  notice of the taking of the corporate  action  without a meeting by less
than unanimous written consent shall be given to those stockholders who have not
consented in writing.

     (b) A telegram, cablegram or other electronic transmission consenting to an
action to be taken and  transmitted  by a stockholder  or  proxyholder,  or by a
person or persons  authorized to act for a stockholder or proxyholder,  shall be
deemed  to be  written,  signed  and  dated for the  purposes  of this  section,
provided that any such telegram, cablegram or other electronic transmission sets
forth or is delivered with  information from which the Corporation can determine
(i)  that  the  telegram,   cablegram  or  other  electronic   transmission  was

                                       3

transmitted  by  the  stockholder  or  proxyholder  or by a  person  or  persons
authorized to act for the  stockholder or proxyholder and (ii) the date on which
such stockholder or proxyholder or authorized person or persons transmitted such
telegram, cablegram or electronic transmission. The date on which such telegram,
cablegram or electronic  transmission  is transmitted  shall be deemed to be the
date on which such consent was signed.  No consent given by telegram,  cablegram
or other  electronic  transmission  shall be deemed to have been delivered until
such  consent  is  reproduced  in paper  form and until such paper form shall be
delivered to the  Corporation by delivery to its registered  office in the State
of  Nevada,  its  principal  place of  business  or an  officer  or agent of the
Corporation  having  custody of the book in which  proceedings  of  meetings  of
stockholders are recorded.  Delivery made to the Corporation's registered office
in the State of Nevada shall be made by hand or by certified or registered mail,
return receipt requested. Notwithstanding the foregoing limitations on delivery,
consents given by telegram,  cablegram or other  electronic  transmission may be
otherwise  delivered to the principal place of business of the Corporation or to
an  officer  or agent of the  Corporation  having  custody  of the book in which
proceedings  of meetings of  stockholders  are recorded if, to the extent and in
the manner provided by resolution of the board of directors of the  Corporation.
Any copy,  facsimile or other reliable  reproduction of a consent in writing may
be substituted or used in lieu of the original  writing for any and all purposes
for which the original writing could be used, provided that such copy, facsimile
or other  reproduction  shall be a complete  reproduction of the entire original
writing.

                                   Article II
                               BOARD OF DIRECTORS

Section 2.1.      Election; Resignation; Removal; Vacancies

     At the first  annual  meeting of  stockholders  and at each annual  meeting
thereafter,  the  stockholders  shall elect Directors to replace those Directors
whose terms then  expire.  Any Director may resign at any time upon notice given
in writing or by electronic transmission to the Corporation. Any director or the
whole Board of Directors  may be removed for cause or without cause by vote of a
majority of the  stockholders at a special meeting called for that purpose.  Any
vacancy  occurring  in the  Board  of  Directors,  whether  resulting  from  the
resignation  or  removal  of a  Director  or from an  increase  in the number of
Directors as provided in the Articles,  may be filled by the affirmative vote of
a majority of the Board,  although such majority is less than a quorum,  or by a
plurality  of the votes cast at a meeting of  stockholders,  and any Director so
elected shall hold office until the expiration of his or her term.

Section 2.2.      Regular Meetings

     Regular  meetings  of the  Board of  Directors  may be held at such  places
within  or  without  the  State of  Nevada  and at such  times  as the  Board of
Directors may from time to time determine,  and if so determined notices thereof
need not be given.

Section 2.3.      Special Meetings

     Special meetings of the Board of Directors may be held at any time or place
within or without the State of Nevada whenever called by the President, any Vice
President, the Secretary, or by any member of the Board of Directors. Reasonable
notice thereof shall be given by the person or persons calling the meeting,  not
later than the second day before the date of the special meeting.

Section 2.4.      Telephonic Meetings Permitted

     Members  of the Board of  Directors,  or any  committee  designated  by the
Board,  may  participate  in a meeting  of such Board or  committee  by means of
conference  telephone  or other  communications  equipment by means of which all
persons participating in the meeting can hear each other, and participation in a
meeting  pursuant  to this bylaw  shall  constitute  presence  in person at such
meeting.

Section 2.5.      Quorum; Vote Required for Action

     At all  meetings  of the Board of  Directors  a majority of the whole Board
shall  constitute a quorum for the  transaction of business.  Except in cases in
which the Articles of Incorporation or these Bylaws otherwise provide,  the vote
of a majority of the directors present at a meeting at which a quorum is present
shall be the act of the Board of Directors.

                                       4

Section 2.6.      Administration of Meetings

     Meetings of the Board of Directors  shall be presided  over by the Chairman
of the  Board,  if any,  or in his or her  absence by the Vice  Chairman  of the
Board, if any, or in his or her absence by the President, or in their absence by
a chairman  chosen at the meeting.  The Secretary  shall act as secretary of the
meeting,  but in his or her absence the  chairman of the meeting may appoint any
person to act as secretary of the meeting.

Section 2.7.      Informal Action by Directors

     Unless  otherwise  restricted  by the  Articles of  Incorporation  or these
Bylaws, any action required or permitted to be taken at any meeting of the Board
of Directors or of any  committee  may be taken without a meeting if all members
of the Board of Directors or such committee, as the case may be, consent thereto
in  writing or by  electronic  transmission,  and the  writing  or  writings  or
electronic   transmission  or  transmissions  are  filed  with  the  minutes  of
proceedings  of the Board of  Directors  or  committee.  Such filing shall be in
paper  form if the  minutes  are  maintained  in  paper  form  and  shall  be in
electronic form if the minutes are maintained in electronic form.

Section 2.8.      Chairman

     The  Board  of  Directors   may  designate  a  Chairman  (or  one  or  more
Co-Chairmen).  The  Chairman  shall  preside  over the  meetings of the Board of
Directors and of the shareholders at which he or she shall be present.  If there
be more than one, the  Co-Chairmen  designated  by the Board of  Directors  will
perform such duties. The Chairman or Co-Chairmen shall perform such other duties
as may be assigned to him, her or them by the Board of Directors.

Section 2.9.      Committees

     The Board of Directors may, by resolution passed by a majority of the whole
Board of  Directors,  designate one or more  committees.  Each  committee  shall
include one or more of the directors of the  Corporation and may include natural
persons who are not  directors of the  Corporation.  The Board of Directors  may
designate  one or more  directors or other  persons as alternate  members of any
committee,  who may replace any absent or disqualified  member at any meeting of
the committee.  In the absence or disqualification of a member of the committee,
the member or members thereof present at any meeting and not  disqualified  from
voting,  whether or not he or they constitute a quorum, may unanimously  appoint
another member of the Board of Directors to act at the meeting in a place of any
such absent or disqualified member. Any such committee,  to the extent permitted
by law and to the extent  provided in the  resolution of the Board of Directors,
shall  have and may  exercise  all the  powers  and  authority  of the  Board of
Directors in the management of the business and affairs of the Corporation,  and
may authorize the seal of the  Corporation to be affixed to all papers which may
require it. Unless the Board of Directors  otherwise  provides,  each  committee
designated  by the Board of Directors  may make,  alter and repeal rules for the
conduct of its  business.  In the absence of such rules,  each  committee  shall
conduct its business in the same manner as the Board of  Directors  conducts its
business pursuant to Article II of these Bylaws.

                                  Article III
                                    OFFICERS

Section 3.1.      Election of Executive Officers; Term of Office

     The officers of the Corporation shall include a President,  a Secretary and
a  Treasurer,  and may  include a Chairman  (or one or more  Co-Chairmen  of the
Board), a Vice Chairman, one or more Vice Presidents, a Chief Operating Officer,
a Chief  Financial  Officer,  one or more Assistant  Secretaries and one or more
Assistant Treasurers.  In addition, the Board of Directors may from time to time
appoint  such  other  officers  with such  powers  and duties as they shall seem
necessary  or  desirable.  Any number of offices may be held by the same person.
Each such  officer  shall hold  office  until the first  meeting of the Board of
Directors  after the annual meeting of  shareholders  next succeeding his or her
election,  and until his or her  successor is elected and qualified or until his
or her earlier resignation or removal.

                                       5

Section 3.2.      Resignation; Removal; Vacancies

     Any officer may resign at any time upon written notice to the  Corporation.
The Board of Directors may remove any officer with or without cause at any time,
but such removal shall be without  prejudice to the  contractual  rights of such
officer,  if any, with the Corporation.  Any vacancy  occurring in any office of
the  Corporation by death,  resignation,  removal or otherwise may be filled for
the  unexpired  portion of the term by the Board of  Directors at any regular or
special meeting.

Section 3.3.      Powers and Duties of Executive Officers

     The  officers of the  Corporation  shall have such powers and duties in the
management  of the  Corporation  as may be  prescribed by the Board of Directors
and, to the extent not so provided,  as set forth below  (subject to the control
of the Board of Directors):

     (a) Chief Executive  Officer.  The Board of Directors may designate a Chief
Executive  Officer.  In the absence of such designation,  the President shall be
the Chief Executive  Officer of the  Corporation.  The Chief  Executive  Officer
shall have general and active management and control of the overall business and
affairs of the Corporation  subject to the control of the Board. He or she shall
see that all orders and resolutions of the Board are carried into effect and, in
connection therewith, shall be authorized to delegate to the President and other
executive  officers such of his or her powers and duties as the Chief  Executive
Officer  may deem  advisable.  He or she shall also have such  other  powers and
duties as may be assigned from time to time by the Board.

     (b) President.  The President shall have general and active  management and
control over the daily  operations  of the  Corporation,  including the right to
hire and discharge  employees other than elective  officers,  subject however to
the control of the Board and the Chief Executive  Officer if designated.  In the
absence of a designation of a Chief Executive Officer by the Board of Directors,
the  President  shall be the Chief  Executive  Officer;  and in the absence of a
designation  of a  Chief  Operating  Officer  by the  Board  of  Directors,  the
President  shall be the Chief  Operating  Officer.  The  President  shall,  when
present and in the absence or disability of the Chairman or the Chief  Executive
Officer,  preside  at all  meetings  of the  shareholders  and of the  Board  of
Directors.  The  President  may sign,  either  alone or with the  Secretary,  an
Assistant  Secretary or any other proper  officer of the  Corporation  thereunto
authorized by the Board of Directors, certificates for shares of the Corporation
and any deeds, mortgages, bonds, contracts, or other instruments which the Board
of Directors has  authorized  to be executed,  except in cases where the signing
and execution thereof shall be expressly  delegated by the Board of Directors or
by these Bylaws to some other officer or agent of the  Corporation,  or shall be
required by law to be otherwise  signed or  executed.  He or she shall also have
such other  powers and duties as are  incident to the office of  President or as
may be assigned from time to time by the Board or the Chief Executive Officer.

     (c) Chief Operating  Officer.  The Board of Directors may designate a Chief
Operating  Officer.  In the absence of such designation,  the President shall be
the Chief Operating Officer.  The Chief Operating Officer shall have such powers
and  duties  as may be  assigned  from  time to time by the  Board or the  Chief
Executive Officer.

     (d) Chief Financial  Officer.  The Board of Directors may designate a Chief
Financial  Officer.  In the absence of a designation of a Treasurer by the Board
of Directors,  the Chief Financial  Officer  Treasurer shall be the Treasurer of
the Corporation.  The Chief Financial  Officer shall have such powers and duties
as may be  assigned  from  time to  time by the  Board  or the  Chief  Executive
Officer.

     (e)  Vice-Presidents.  The  Vice-Presidents,  if any,  in  order  of  their
seniority or in any other order  determined by the Board of Directors  shall, in
the absence or disability of the President,  perform the duties and exercise the
powers  of the  President  and  shall  severally  assist  the  President  in the
management  of the  business  of  the  Corporation  and  the  implementation  of
resolutions  of the Board,  and in the  performance  of such other duties as the
President  may from time to time  prescribe.  The duties of any  assistant  vice
presidents shall be as set by the President.

     (f)  Secretary.   The  Secretary   shall:  (i)  keep  the  minutes  of  the
shareholders'  and of the  Board of  Directors'  meetings  in one or more  books
provided  for  that  purpose;  (ii)  see that  all  notices  are  duly  given in
accordance  with the  provisions of these Bylaws or as required by law; (iii) be
custodian of the corporate  records and of the seal (if any) of the  Corporation
and see that said seal is affixed to all  documents,  the  execution of which on
behalf  of the  Corporation  under  its  seal is duly  authorized;  (iv)  keep a

                                       6

register of the post office address of each shareholder which shall be furnished
to the  Secretary  by such  shareholder;  (v)  sign,  with  the  President  or a
Vice-President,  certificates  for shares of the  Corporation,  the  issuance of
which shall have been  authorized by resolution of the Board of Directors;  (vi)
have general charge of the share transfer books of the Corporation; and (vii) in
general perform all duties as from time to time may be assigned to the Secretary
by the Board of Directors, the Chief Executive Officer or the President.

     (g) Assistant Secretaries.  The Assistant Secretaries,  if any, in order of
their  seniority or in any other order  determined  by the Board  shall,  in the
absence or  disability  of the  Secretary,  perform the duties and  exercise the
powers of the  Secretary  and shall  perform  such other  duties as the Board of
Directors or the Secretary may from time to time prescribe.

     (h)  Treasurer.  The  Treasurer  shall  have the  custody  of the funds and
securities  of the  Corporation  and shall keep full and  accurate  accounts  of
receipts and  disbursements in books belonging to the Corporation and shall keep
full and accurate  accounts of receipts and  disbursements in books belonging to
the Corporation  and shall deposit all moneys and other valuable  effects in the
name  and to the  credit  of the  Corporation  in  such  depositories  as may be
designated by the Board of Directors. In the absence of a designation of a Chief
Financial  Officer by the Board of Directors,  the Treasurer  shall be the Chief
Financial Officer of the Corporation.  The Treasurer shall disburse the funds of
the Corporation as may be ordered by the Board,  taking proper vouchers for such
disbursements,  and shall render to the Chief Executive  Officer,  President and
directors,  at the regular  meetings of the Board,  or whenever they may require
it, an account of all his or her  transactions as Treasurer and of the financial
condition  of the  Corporation.  If  required  by the  Board of  Directors,  the
Treasurer  shall give the Corporation a bond for such term, in such sum and with
such surety or sureties as shall be  satisfactory  to the Board for the faithful
performance  of the duties of his or her office and for the  restoration  to the
Corporation,  in case of his or her death,  resignation,  retirement  or removal
from  office,  of all  books,  papers,  vouchers,  money and other  property  of
whatever kind in his or her possession or under his or her control  belonging to
the Corporation.

     (i) Assistant Treasurers. The Assistant Treasurers, if any, in the order of
their  seniority  or in any other order  determined  by the Board,  shall in the
absence or  disability  of the  Treasurer,  perform the duties and  exercise the
power of the  Treasurer  and shall  perform  such  other  duties as the Board of
Directors or the Treasurer shall prescribe.

                                   Article IV
                                      STOCK

Section 4.1.      Certificates

     Every holder of stock shall be entitled to have a certificate  signed by or
in the name of the Corporation by the Chairman, the Chief Executive Officer, the
President or a Vice  President of the  Corporation,  and by the  Secretary,  the
Treasurer  or  an  Assistant   Secretary  or  an  Assistant   Treasurer  of  the
Corporation, certifying the number of shares owned by him in the Corporation. In
case any officer, transfer agent, or registrar who has signed or whose facsimile
signature  has been  placed  upon a  certificate  shall  have  ceased to be such
officer,  transfer agent, or registrar before such certificate is issued, it may
be issued by the  Corporation  with the same effect as if he were such  officer,
transfer agent, or registrar at the date of issue.

Section 4.2.      Lost, Stolen or Destroyed Stock Certificates

     The  Corporation  may issue a new  certificate of stock in the place of any
certificate  theretofore  issued by it,  alleged  to have been  lost,  stolen or
destroyed,  and the  Corporation  may require  the owner of the lost,  stolen or
destroyed  certificate,  or  his  or  her  legal  representative,  to  give  the
Corporation a bond sufficient to indemnify it against any claim that may be made
against it on account of the  alleged  loss,  theft or  destruction  of any such
certificate or the issuance of such new certificate.

Section 4.3.      Registration of Transfer

     Upon surrender to the  Corporation or any transfer agent of the Corporation
of a certificate  for stock duly endorsed or accompanied  by proper  evidence of

                                       7

succession,  assignment or authority to transfer, the Corporation shall issue or
cause its  transfer  agent to issue a new  certificate  to the  person  entitled
thereto, cancel the old certificate and record the transaction upon its books.

Section 4.4.      Registered Stockholders

     Except as otherwise  provided by law, the Corporation  shall be entitled to
recognize the exclusive  right of a person  registered on its books as the owner
of stock to receive dividends or other distributions, and to vote as such owner,
and to hold liable for calls and assessments a person registered on its books as
the owner of stock,  and shall not be bound to recognize  any equitable or legal
claim to or interest in such stock on the part of any other person.

                                   Article V
                                  MISCELLANEOUS

Section 5.1.      Fiscal Year

     The fiscal year of the Corporation shall be determined by resolution of the
Board of Directors.

Section 5.2.      Seal

     The  corporate  seal,  if one,  shall  have  the  name  of the  Corporation
inscribed thereon and shall be in such form as may be approved from time to time
by the Board of Directors.

Section 5.3.      Waiver of Notice of Meetings of Stockholders, Directors and
                  Committees

     Any written waiver of notice, signed by the person entitled to notice, or a
waiver by  electronic  transmission  by the person  entitled to notice,  whether
before or after the time stated therein,  shall be deemed  equivalent to notice.
Attendance of a person at a meeting shall  constitute a waiver of notice of such
meeting,  except when the person  attends a meeting  for the express  purpose of
objecting,  at the beginning of the meeting,  to the transaction of any business
because the meeting is not lawfully called or convened.  Neither the business to
be  transacted  at,  nor the  purpose of any  regular or special  meeting of the
stockholders,  directors,  or members of a committee  need be  specified  in any
written waiver of notice or any waiver by electronic transmission.

Section 5.4.      Interested Directors; Quorum

     No contract or transaction  between the  Corporation and one or more of its
directors or officers,  or between the  Corporation  and any other  corporation,
partnership,  association,  or other  organization  in which  one or more of its
directors or officers are directors or officers,  or have a financial  interest,
shall be void or voidable solely for this reason, or solely because the director
or  officer  is  present  at or  participates  in the  meeting  of the  Board or
committee which authorizes the contract or transaction, or solely because his or
her or their votes are counted for such purpose,  if: (a) the material  facts as
to his or her relationship or interest and as to the contract or transaction are
disclosed or are known to the Board of Directors or the committee, and the Board
or  committee  in good faith  authorizes  the  contract  or  transaction  by the
affirmative votes of a majority of the disinterested directors,  even though the
disinterested  directors be less than a quorum;  or (b) the material facts as to
his or her  relationship  or interest and as to the contract or transaction  are
disclosed or are known to the  stockholders  entitled to vote  thereon,  and the
contract or  transaction is  specifically  approved in good faith by vote of the
stockholders;  or (c) the contract or transaction is fair as to the  Corporation
as of the time it is authorized, approved or ratified by the Board of Directors,
a committee, or the stockholders.  Common or interested directors may be counted
in  determining  the presence of a quorum at a meeting of the Board of Directors
or of a committee which authorizes the contract or transaction.

Section 5.5.      Form of Records

     Any records  maintained  by the  Corporation  in the regular  course of its
business, including its stock ledger, books of account, and minute books, may be
kept on, or by means of, or be in the form of any information  storage device or
method,  provided that the records so kept can be converted into clearly legible
paper form  within a  reasonable  time.  The  Corporation  shall so convert  any
records so kept upon the request of any person  entitled to inspect such records
pursuant to any provision of this chapter.

                                       8

Section 5.6.      Dividends and Distributions

     Subject  to  all  applicable  requirements  of law  and  to any  applicable
provisions of the Articles of  Incorporation,  these Bylaws and any indenture or
other agreement to which the Corporation is a party or by which it is bound, the
Board of Directors may declare to be payable,  in cash, in other  property or in
shares of the  Corporation's  stock of any class or series,  such  dividends and
distributions  upon or in respect of outstanding stock of the Corporation of any
class or  series  as the  Board  may at any time or from time to time deem to be
advisable.  Before  declaring  any such dividend or  distribution,  the Board of
Directors  may  cause to be set  aside,  out of any funds or other  property  or
assets of the  Corporation  legally  available  for the payment of  dividends or
distributions,  such sum or sums as the Board, in the absolute discretion of its
members,   may  consider  to  be  proper  as  a  reserve  or  reserves  to  meet
contingencies,  or for equalizing dividends, or for repairing or maintaining any
property  of the  Corporation,  or for such other  purpose as the Board may deem
conducive  to the  interest  of the  Corporation,  and the Board  may  modify or
abolish any such reserve in the manner in which it was created.

Section 5.7.      Checks, Notes, etc.

     All  checks  or  other  orders  for  payment  of money  and  notes or other
instrument  evidencing  indebtedness or obligations of the Corporation  shall be
signed by such  officer or officers or such other person or persons as the Board
of Directors may from time to time designate.

Section 5.8.      Securities of other Corporations; Acting as General Partner

     Unless  otherwise  ordered by the Board of Directors,  the Chief  Executive
Officer or the  President  shall have full power and  authority on behalf of the
Corporation:  (a) to attend  and to act and to vote,  or to  execute  proxies to
vote,  at  any  meetings  of  stockholders  of  any  corporation  in  which  the
Corporation  may hold  stock,  and at any such  meeting  shall  possess  and may
exercise,  in person or by proxy,  any and all  rights,  powers  and  privileges
incident to the  ownership of such stock;  and (b) to exercise all rights of the
general partner in any  partnership of which the Corporation  shall be a general
partner.  The Board of Directors may, by resolution,  from time to time,  confer
like powers upon any other person or persons.

Section 5.9.      Electronic Transmissions

     The term "electronic transmission",  where used herein, shall mean any form
of  communication,  not directly  involving the physical  transmission of paper,
that  creates  a record  that may be  retained,  retrieved,  and  reviewed  by a
recipient thereof,  and that may be directly  reproduced in paper form by such a
recipient through an automated process.

Section 5.10.     Amendment of Bylaws

     These Bylaws may be altered or repealed,  and new Bylaws made,  only as set
forth in the Articles of Incorporation.

                                       9

                                                                   Exhibit 4.2.2

January 31, 2003

Mr. Stuart Fuchs
Managing Principal
Gryffindor Capital Partners I, L.L.C.
150 North Wacker Drive, Suite 800
Chicago, Illinois  60606

         Re: Amendment to Transaction Documents

Dear Mr. Fuchs,

     This letter is to confirm that the Transaction Documents (as defined in the
Amended and Restated  Senior  Secured  Convertible  Note dated as of January 31,
2003 from Provectus  Pharmaceuticals,  Inc.  ("Provectus") to Gryffindor Capital
Partners I, L.L.C.) and the  Certificate of the President of Provectus  dated as
of November  26, 2002 (the  "Certificate")  shall be amended by modifying in the
Transaction  Documents  and  Certificate  all  references  to the  amount of One
Million and 00/100  Dollars  ($1,000,000),  to the amount of One Million  Twenty
Five Thousand Nine Hundred and Fifty Nine Dollars ($1,025,959).

     If the terms of this letter are  acceptable,  please so indicate by signing
this letter below and returning it to me.

                         Very truly yours,

                         PROVECTUS PHARMACEUTICALS, INC

                         By: /s/ Timothy C. Scott
                            -----------------------------
                         Name: Timothy C. Scott, Ph.D.
                         Its: President

                         ACCEPTED AND AGREED:

                         GRYFFINDOR CAPITAL PARTNERS I, L.L.C.

                         By: /s/ Stuart Fuchs
                            -------------------------------------------------
                         Name: Stuart Fuchs
                         Its: Managing Principal


                                                                     Exhibit 4.3


THIS NOTE AND THE SECURITIES  REPRESENTED  HEREBY HAVE NOT BEEN REGISTERED UNDER
THE SECURITIES ACT OF 1933 ("ACT") OR ANY APPLICABLE STATE SECURITIES LAWS. THEY
MAY NOT BE SOLD,  OFFERED FOR SALE,  PLEDGED OR HYPOTHECATED IN THE ABSENCE OF A
REGISTRATION  STATEMENT IN EFFECT WITH RESPECT TO THE SECURITIES  UNDER SUCH ACT
OR AN OPINION OF COUNSEL  SATISFACTORY TO THE BORROWER THAT SUCH REGISTRATION IS
NOT REQUIRED.

              AMENDED AND RESTATED SENIOR SECURED CONVERTIBLE NOTE


$1,025,959                                                      January 31, 2003


     FOR VALUE  RECEIVED,  PROVECTUS  PHARMACEUTICALS,  INC.  (the  "Borrower"),
promises  to  pay  to  the  order  of  GRYFFINDOR  CAPITAL  PARTNERS  I,  L.L.C.
("Lender"),  at the  Borrower's  office  at 7327  Oak  Ridge  Highway,  Suite A,
Knoxville,  TN 37931,  or such other place as the holder hereof may from time to
time appoint in writing,  in lawful money of the United  States of America,  the
principal  sum of One Million  Twenty Five  Thousand Nine Hundred and Fifty Nine
Dollars  ($1,025,959),  or such lesser  principal  amount as may be  outstanding
hereunder,  together with interest payable quarterly in arrears on the principal
balance  from time to time  unpaid at the rate of eight  percent  (8%) per annum
(the "Loan Rate") until  maturity.  From and after the occurrence of an Event of
Default (as hereinafter defined),  the outstanding principal amount hereof shall
bear  interest  at the rate of twelve  percent  (12%) per  annum  (the  "Default
Rate").  Interest will be computed on the daily  principal  balance  outstanding
during  the period  from the last  payment  date to the  current  payment  date.
Interest shall be the product resulting when multiplying the rate of interest by
the principal balance outstanding,  dividing by 360, and then multiplying by the
actual number of days interest has accrued.

     This  Amended  and  Restated  Senior  Secured  Convertible  Note amends and
restates that certain  Senior Secured  Convertible  Note dated November 26, 2002
from the Borrower in favor of the Lender in the original principal amount of One
Million  and  00/100  Dollars  ($1,000,000)  (the  "Prior  Note")  and  is not a
repayment or novation of the Prior Note.

     The  following  is a statement  of the rights of Lender under this Note and
the conditions to which this Note and the Borrower are subject, and to which the
Borrower hereby agrees as follows:

     1. Purchase  Agreement.  This Senior Secured  Convertible  Promissory  Note
(this  "Note") is executed and  delivered by the Borrower  pursuant to the terms
and conditions of the Convertible  Secured  Promissory Note and Warrant Purchase
Agreement of even date herewith between,  among others,  the Borrower and Lender
(the "Purchase Agreement").  This Note is subject to the terms and conditions of
the  Purchase  Agreement.  Any  capitalized  term used herein and not  otherwise
defined herein shall have the meaning given to it in the Purchase Agreement.

     2. Repayment Terms.  Subject to Lender's conversion rights set forth below,
the Borrower  shall pay the  outstanding  principal  balance and all accrued and
unpaid interest due hereunder on November 26, 2004 (the "Maturity Date").

     Notwithstanding  anything to the contrary  contained herein, if at any time
prior to the Conversion Start Date (as hereinafter defined),  the Borrower shall
fail  to  make  any  quarterly  payment  of  interest  due  hereunder  (each,  a
"Pre-Conversion  Unmatured  Interest  Default"),  the Borrower shall forfeit any
right to pay the amount of such  Pre-Conversion  Unmatured  Interest Default (or
cause any other entity or affiliate of the Borrower, including any guarantor, to
pay such amount) and the outstanding principal amount hereof shall bear interest
at the  Default  Rate until such time as this Note is repaid in full or the full
amount due under this Note is converted  in  accordance  with the terms  herein;
provided,  further,  that,  at any time after the  Conversion  Start  Date,  the
Borrower  shall fail to make any  quarterly  payment of interest due  hereunder,
such failure shall constitute an Event of Default under Section 7(a) hereof.


     3. Optional  Conversion.  Subject to Lender's  conversion right pursuant to
Section 4.1.6 of the Shareholders' Agreement, dated as of even date herewith, by
and among,  Borrower,  Lender and  certain  other  shareholders,  commencing  on
November  26, 2003 (the  "Conversion  Start  Date")  through and  including  the
Maturity Date,  Lender, in its sole discretion,  shall have the right to convert
the outstanding principal and accrued and unpaid interest on this Note, in whole
or in part, into certain shares of stock of the Borrower as follows:

          a)  Principal.  Lender  shall  have the  right to  convert  all or any
     portion of the outstanding principal amount under the Note into that number
     of common  shares of the  Borrower  equal to the amount of  principal to be
     converted  divided by the conversion  price of $0.73655655  (the "Principal
     Shares"),  which conversion price was determined based on (i) Lender owning
     that number of shares of common stock of the Borrower  constituting  twelve
     and  seven  hundred   eighty-three   thousandths   percent  (12.783%)  (the
     "Ownership  Percent") of the Borrower  (assuming that the Principal  Shares
     are  converted  and the shares under the Warrant are  exercised at the same
     time) at a pre-money  valuation of Five Million Dollars  ($5,000,000),  and
     (ii) (a) outstanding  shares and commitments to issue shares, in the amount
     of 9,050,763  for twelve and  one-half  percent  (12.50%) of the  Ownership
     Percent, and (b) outstanding shares and commitments to issue shares, in the
     amount of  10,896,595  for two hundred  eighty  three  thousandths  percent
     (0.283%) of the Ownership  Percent,  as  represented by the Borrower in the
     Purchase  Agreement,  which  amounts  exclude  those  shares  reserved  for
     issuance under the Borrower's employee stock option plan.

          b)  Interest.  Lender  also shall have the right to convert all or any
     portion of the accrued and unpaid  interest under the Note into that number
     of common  shares of the  Borrower  equal to the amount of  principal to be
     converted divided by the conversion price of $0.55 (the "Interest Shares"),
     which conversion price was determined based on (i) a pre-money valuation of
     Five  Million  Dollars  ($5,000,000),   and  (ii)  outstanding  shares  and
     commitments to issue shares, in the amount of 9,050,763,  as represented by
     the Borrower in the Purchase Agreement,  which amount excludes those shares
     reserved for issuance under the Borrower's employee stock option plan.

          c) Mechanics of Conversion. Before Lender shall be entitled to convert
     this  Note  into  the   Principal   Shares   and/or  the  Interest   Shares
     (collectively,  the "Acquired  Securities"),  as  applicable,  Lender shall
     surrender  this Note,  duly  endorsed,  at the office of the Borrower,  and
     shall give written notice to the Borrower at its principal corporate office
     of the  election to the same and shall  state  therein the name or names in
     which the certificate or certificates for the Acquired Securities are to be
     issued. The Borrower, promptly thereafter,  shall issue and deliver to such
     persons at the address  specified by Lender,  a certificate or certificates
     for  the  Acquired  Securities  to  which  the  Holder  is  entitled.  Such
     conversion shall be deemed to have been made immediately prior to the close
     of business  on the date of such  surrender  of this Note,  and the persons
     entitled to receive the Acquired  Securities  issuable upon such conversion
     shall be treated for all  purposes as the record  holder or holders of such
     Acquired  Securities as of such date. No fractional  shares shall be issued
     upon  conversion of the principal  and/or  interest due under this Note and
     the number of Acquired  Securities  to be issued shall be rounded up to the
     nearest whole share.

          d) Effect of Reorganization,  Reclassification,  Consolidation, Merger
     or Sale. If at any time while this Note is  outstanding  there shall be any
     reorganization or  reclassification of the capital stock of the Borrower or
     any consolidation or merger of the Borrower with another corporation (other
     than a  consolidation  or  merger in which the  Borrower  is the  surviving
     entity and which does not result in any change in the Common Stock), or any
     sale or other  disposition by the Borrower of all or  substantially  all of
     its  assets  to any  other  corporation,  the  holder  of this  Note  shall
     thereafter  upon  conversion of this Note be entitled to receive the number
     of shares of stock or other  securities or property of the Borrower,  or of
     the successor  corporation  resulting from such consolidation or merger, as
     the case may be, to which the Acquired Securities (and any other securities
     and  property)  of the  Borrower,  deliverable  upon  the  exercise  of the
     conversion   under  this  Note,   would  have  been   entitled   upon  such
     reorganization,  reclassification of capital stock, consolidation,  merger,
     sale or other disposition if this Note had been exercised immediately prior

                                       2


     to such reorganization,  reclassification of capital stock,  consolidation,
     merger, sale or other disposition. In any such case, appropriate adjustment
     (as  determined  in good faith by the Board of Directors  of the  Borrower)
     shall be made in the  application  of the provisions set forth in this Note
     with respect to the rights and  interests  thereafter of the holder of this
     Note to the end that the provisions set forth in this Note (including those
     relating  to  adjustments  of  the  number  of  shares  issuable  upon  the
     conversion  of  this  Note)  shall  thereafter  be  applicable,  as near as
     reasonably may be, in relation to any shares or other  property  thereafter
     deliverable  upon the conversion  hereof as if this Note had been converted
     immediately  prior  to such  reorganization,  reclassification  of  capital
     stock,  consolidation,  merger,  sale or other  disposition  and the holder
     hereof had  carried out the terms of the  exchange as provided  for by such
     reorganization, reclassification of capital stock, consolidation or merger.
     The Borrower  shall not effect any such  reorganization,  consolidation  or
     merger unless,  upon or prior to the  consummation  thereof,  the successor
     corporation shall assume by written instrument the obligation to deliver to
     the holder  hereof  such shares of stock,  securities,  cash or property as
     such holder shall be entitled to purchase in accordance  with the foregoing
     provisions.

          e) Effect of a Stock Dividends,  Splits, Etc. If the Borrower shall at
     any time  after  the date  hereof  fix a record  date for the  subdivision,
     split-up  or  stock   dividend  of  shares  of  its  Common  Stock,   then,
     concurrently  with  the  effectiveness  of such  subdivision,  split-up  or
     dividend,  the number of shares of Common Stock  issuable on  conversion of
     this Note shall be increased in proportion to such increase in  outstanding
     shares of Common Stock.

          f) Prior Notice as to Certain Events. In case at any time:

               (i) the  Borrower  shall offer for  subscription  pro rata to the
          holders  of its  Common  Stock any  additional  shares of stock of any
          class or any other rights; or

               (ii) there shall be any reorganization or reclassification of the
          capital  stock of the  Borrower,  or  consolidation  or  merger of the
          Borrower with another  corporation  or a sale or disposition of all or
          substantially all its assets; or

               (iii)  there  shall be a voluntary  or  involuntary  dissolution,
          liquidation or winding up of the Borrower;

     then, in each of said cases,  the Borrower shall give prior written notice,
     by first class mail, postage prepaid,  addressed to the holder of this Note
     at the address of such holder as shown in Section  9(k) below,  of the date
     on which (iv) the books of the  Borrower  shall close or a record  shall be
     taken for such stock dividend,  distribution or subscription  rights or (v)
     such  reorganization,   reclassification,   consolidation,   merger,  sale,
     dissolution,  liquidation  or winding up shall take place,  as the case may
     be. Such notice also shall  specify the date as of which the holders of the
     Common  Stock  of  record  shall   participate  in  said  stock   dividend,
     distribution or subscription  rights or shall be entitled to exchange their
     Common  Stock  for  securities  or other  property  deliverable  upon  such
     reorganization, reclassification, consolidation, merger, sale, dissolution,
     liquidation or winding up, as the case may be. Such written notice shall be
     given at least ten (10) days prior to the action in  question  and not less
     than  ten  (10)  days  prior to the  record  date or the date on which  the
     Borrower's transfer books are closed in respect thereto.

          g) Reservation  of Common Stock.  The Borrower will at all times after
     the  date  hereof   reserve  and  keep  available  for  issuance  upon  the
     conversions  described herein such number of authorized and unissued shares
     of Common Stock as will be sufficient to permit the  conversions  described
     herein,  and upon such issuance such shares of Common Stock will be validly
     issued,  fully paid and nonassessable,  and free from all liens and charges
     with respect to the issuance thereof.

     4.  Prepayment.  The Borrower will not have the right at any time to prepay
this Note in whole or in part,  except in the event that the Borrower  obtains a
commitment  from  another  investor  for an amount not less than  Three  Million
Dollars  ($3,000,000) in exchange for shares of the Borrower,  which  commitment
shall  include an  obligation  on the part of such investor to repay in full the
outstanding principal balance plus all accrued and unpaid interest thereon owing
hereunder  (the  "Obligations"),  and such  commitment  is on  terms  reasonably
acceptable to Lender.  In such event, the Borrower may prepay this Note in full;
provided,  however,  such prepayment  shall, as determined by Lender in its sole

                                       3

discretion, take the form of either: (a) repayment in full of the Obligations or
(b) conversion of the Obligations into shares of common stock of the Borrower in
accordance  with the  conversion  terms  set forth in  Section 3 above;  further
provided,  however, if the market price of the Borrower's common shares are less
than the conversion price of the Principal Shares under this Note,  Lender shall
have the right to convert  the  Obligations  into the same  series of  preferred
stock that such  investor is  purchasing  with the same rights,  privileges  and
preferences  granted to such  investor,  except with  respect to the  conversion
price which, for Lender, will be the conversion price hereunder.

     5. Security. This Note is secured by, among other things, the following:

          a) a Security  Agreement,  dated the date hereof  between the Borrower
     and Lender (the "Provectus  Security  Agreement"),  which encumbers certain
     collateral described therein;

          b) a Stock Pledge  Agreement,  dated the date hereof from the Borrower
     in favor of Lender (the "Stock Pledge Agreement") providing for a pledge of
     all of the common stock of Xantech Pharmaceuticals, Inc. ("Xantech");

          c) a Trademark  Collateral Security  Agreement,  dated the date hereof
     between Provectus and Lender which encumbers certain  collateral  described
     therein (the "Trademark Security Agreement");

          d) a Patent and  License  Security  Agreement,  dated the date  hereof
     between Provectus and Lender which encumbers certain  collateral  described
     therein (the "Patent Security Agreement");

          e) a  Copyright  Security  Agreement,  dated the date  hereof  between
     Provectus and Lender which encumbers certain  collateral  described therein
     (the "Copyright  Security  Agreement" and together with the Patent Security
     Agreement, the Stock Pledge Agreement, the Trademark Security Agreement and
     the Provectus Security Agreement, the "Security Documents"); and

          f) such  other  agreements  and  documents  as Lender  shall  require,
     including,  without  limitation that certain Guaranty of even date herewith
     from Xantech in favor of Lender (the "Guaranty").

     The Purchase Agreement, this Note, the Guaranty, the Security Documents and
any and all other  agreements  presently  existing or hereafter  entered into in
connection  therewith or which evidence and/or secure any indebtedness  from the
Borrower  to  Lender  shall  hereinafter  be  collectively  referred  to as  the
"Transaction Documents." Any and all collateral referred to in or granted by the
Security Documents is hereinafter  collectively referred to as the "Collateral."
The terms, covenants, conditions, provisions, stipulations and agreements of the
Transaction  Documents  are hereby made a part of this Note,  to the same extent
and with the same effect as if they were fully set forth  herein.  The  Borrower
does hereby covenant to abide by and comply with each and every term,  covenant,
condition,  provision,  stipulation  and agreement set forth in the  Transaction
Documents.

     The Borrower  shall remain  liable for the payment of this Note,  including
interest, notwithstanding any extensions of time of payment or any indulgence of
any kind or nature that Lender may grant to the Borrower or any subsequent owner
of the  Collateral,  whether  with or without  notice to the  Borrower,  and the
Borrower hereby  expressly  waives such notice.  No release of any or all of the
security  given for this  obligation  shall  release any other maker,  co-maker,
surety,  guarantor,  or other party hereto in any capacity.  Lender shall not be
required  to look first to the  Collateral  for  payment  of this Note,  but may
proceed against the Borrower in such manner as it deems desirable.

     6. Use of Proceeds. The proceeds of the loan evidenced by this Note will be
used for  working  capital  purposes  of the  Borrower  pursuant  to the  Budget
attached  to the  Purchase  Agreement  as Schedule  2;  provided,  that at least
seventy  percent  (70%) of such  proceeds  must be used for product  production,
general  operating  expenses  (including  salaries or other  employment  costs),
advertising and marketing for the Borrower;  and,  provided,  further,  that not
more than thirty  percent (30%) of such proceeds may be used by the Borrower for
back compensation due to the Borrower's employees or consultants.

                                       4

     7. Event of Default.  The  occurrence  of any one or more of the  following
events  (regardless  of the  reason  therefor)  shall  constitute  an  "Event of
Default" hereunder:

          (a) The Borrower  shall fail to make any payment of  principal  of, or
     interest  on this Note when due and  payable or  declared  due and  payable
     (other than any Pre-Conversion Unmatured Interest Payment).

          (b) The Borrower or Xantech shall fail or neglect to perform,  keep or
     observe any provision of this Note, the Guaranty, the Security Documents or
     any other Loan Document.

          (c) Lender shall fail to have an  enforceable  first  priority lien on
     and security  interest in the Collateral or any default or event of default
     occurs under any of the Security Documents.

          (d) The Borrower or Xantech files a bankruptcy  petition, a bankruptcy
     petition  is filed  against  the  Borrower  which  remains  undismissed  or
     unstayed  for sixty (60)  consecutive  days,  or  Borrower  makes a general
     assignment for the benefit of creditors.

          (e) Any  default by the  Borrower or Xantech,  as  applicable,  occurs
     under the Purchase Agreement or any other Transaction Document.

     Upon the  occurrence  of any  Event of  Default,  Lender  may,  in its sole
discretion,  do one or more  of the  following:  (i)  declare  all  indebtedness
evidenced by this Note to be  immediately  due and payable,  whereupon  all such
indebtedness shall become due and payable, without presentment,  demand, protest
or  further  notice  of any  kind,  all of which  are  expressly  waived  by the
Borrower, and/or (ii) continue to exercise any of its conversion rights pursuant
to Section 3 hereof, and/or (iii) exercise any or all of its rights and remedies
available hereunder or under any of the Security Documents,  the Guaranty or any
other Transaction Documents and applicable law.

     8.  Replacement.  Upon receipt of evidence  reasonably  satisfactory to the
Borrower (an affidavit of Lender shall be satisfactory) of the ownership and the
loss, theft, destruction or mutilation of this Note, and in the case of any such
loss, theft or destruction, upon receipt of indemnity reasonably satisfactory to
the Borrower or, in the case of any such mutilation upon surrender of this Note,
the Borrower shall (at its expense)  execute and deliver in lieu of such Note, a
Note of like kind representing the same rights represented by such lost, stolen,
destroyed or mutilated  Note and dated as of the date to which interest has been
paid on the unpaid  principal amount of the Note so lost stolen,  destroyed,  or
mutilated,  or, if no interest has been paid thereon,  then dated as of the date
of the Note so lost, stolen, destroyed or mutilated.

     9. Miscellaneous

          a) In the event that Lender  institutes  legal  proceedings to enforce
     the  Transaction  Documents,  the  Borrower  agrees  to pay to  Lender,  in
     addition to any indebtedness due and unpaid, all costs and expenses of such
     proceedings, including reasonable attorneys' fees.

          b) Lender shall not by any act of omission or  commission be deemed to
     waive any of its rights or  remedies  hereunder  unless  such  waiver be in
     writing and signed by an authorized  officer of Lender and then only to the
     extent  specifically set forth therein.  A waiver on one occasion shall not
     be construed as continuing or as a bar to or waiver of such right or remedy
     on  any  other  occasion.   All  remedies  conferred  upon  Lender  by  the
     Transaction  Documents shall be cumulative and none is exclusive,  and such
     remedies may be exercised concurrently or consecutively at Lender's option.

          c) Except as  expressly  provided  for in this Note or any other  Loan
     Document,  every  person at any time  liable  for the  payment  of the debt
     evidenced  hereby  waives  presentment  for  payment,   demand,  notice  of
     nonpayment of this Note, protest and notice of protest,  all exemptions and
     homestead  laws and all rights  thereunder  and  consents  that  Lender may
     extend the time of  payment of any part or the whole of the debt,  or grant
     any other modifications or indulgence pertaining to payment of this Note at
     any time, at the request of any other person liable for said debt.

                                       5

          d) This Note is hereby expressly  limited so that in no contingency or
     event  whatsoever,  whether by acceleration of maturity of the indebtedness
     evidenced  hereby or otherwise,  shall the amount paid or agreed to be paid
     to Lender for the use, forbearance or detention of the money advanced or to
     be advanced  hereunder exceed the highest lawful rate permissible under the
     laws of the State of Illinois as applicable  to the Borrower.  If, from any
     circumstances  whatsoever,  fulfillment of any provision of this Note or of
     any of the other  Transaction  Documents  shall, at the time performance of
     such provisions  shall be due, involve the payment of interest in excess of
     that  authorized by law, the obligation to be fulfilled shall be reduced to
     the limit so  authorized  by law,  and if, from any  circumstances,  Lender
     shall ever  receive as  interest an amount  which would  exceed the highest
     lawful  rate  applicable  to the  Borrower,  such  amount  which  would  be
     excessive  interest  shall  be  applied  to the  reduction  of  the  unpaid
     principal  balance  of the  indebtedness  evidenced  hereby  and not to the
     payment of interest.

          e) All covenants,  agreements,  representations  and  warranties  made
     herein and any other  Transaction  Documents are deemed to have been relied
     upon by Lender, notwithstanding any investigation by Lender.

          f) This Note is given and  accepted as evidence of  indebtedness  only
     and not in payment or satisfaction of any indebtedness or obligation.

          g) The form and  essential  validity of this Note shall be governed by
     the  laws of the  State  of  Illinois.  If any  provision  of this  Note is
     prohibited by, or is unlawful or unenforceable under, any applicable law of
     any  jurisdiction,  such  provision  shall,  as to  such  jurisdiction,  be
     ineffective  to the extent of such  prohibition  without  invalidating  the
     remaining provisions hereof; provided that where the provisions of any such
     applicable law may be waived, they hereby are waived by the Borrower to the
     full extent  permitted by law in order that this Note shall be deemed to be
     a valid and binding promissory note in accordance with its terms.

          h)  Time  is of  the  essence  with  respect  to  all  the  Borrower's
     obligations and agreements under this Note.

          i)  This  Note  and  all  the  provisions,  conditions,  promises  and
     covenants  hereof shall inure to the benefit of Lender,  its successors and
     assigns,  and shall be binding in accordance with the terms hereof upon the
     Borrower,  its  successors  and assigns,  provided  nothing herein shall be
     deemed consent to any  assignment  restricted or prohibited by the terms of
     the Transaction Documents.

          j)  All  notices  required  under  this  Note  shall  be  provided  in
     accordance with the terms of the Purchase Agreement.

          k) To induce  Lender to extend to the Borrower  the loan  evidenced by
     this Note,  Borrower  irrevocably agrees that, subject to Lender's sole and
     absolute election,  ALL ACTIONS OR PROCEEDINGS IN ANY WAY ARISING OUT OF OR
     RELATED  TO THIS  NOTE OR ANY LOAN  DOCUMENT  WILL BE  LITIGATED  IN COURTS
     HAVING SITUS IN CHICAGO, ILLINOIS. THE BORROWER HEREBY CONSENTS AND SUBMITS
     TO THE JURISDICTION OF ANY COURT LOCATED WITHIN CHICAGO,  ILLINOIS,  WAIVES
     PERSONAL  SERVICE OF PROCESS  UPON THE  BORROWER,  AND AGREES THAT ALL SUCH
     SERVICE OF PROCESS MAY BE MADE BY REGISTERED  MAIL DIRECTED TO THE BORROWER
     AT THE ADDRESS STATED ON THE SIGNATURE PAGE HEREOF AND SERVICE SO MADE WILL
     BE DEEMED TO BE COMPLETED UPON ACTUAL RECEIPT.

          l) THE BORROWER AND LENDER EACH WAIVES ANY RIGHT TO A TRIAL BY JURY IN
     ANY ACTION OR PROCEEDING TO ENFORCE OR DEFEND ANY RIGHTS UNDER THIS NOTE OR
     ANY  DOCUMENT OR UNDER ANY  AMENDMENT,  INSTRUMENT,  DOCUMENT OR  AGREEMENT
     DELIVERED OR WHICH MAY IN THE FUTURE BE DELIVERED IN  CONNECTION  WITH THIS
     NOTE AND AGREES THAT ANY SUCH ACTION OR  PROCEEDING  WILL BE TRIED BEFORE A

                                       6

     COURT AND NOT BEFORE A JURY. THE BORROWER AGREES THAT THE BORROWER WILL NOT
     ASSERT ANY CLAIM  AGAINST  LENDER ON ANY THEORY OF  LIABILITY  FOR SPECIAL,
     INDIRECT, CONSEQUENTIAL, INCIDENTAL OR PUNITIVE DAMAGES.

                          [Signature Page(s) to Follow]

                                       7


         IN WITNESS WHEREOF, this Note is executed as of the date and year first
set forth above.


                         PROVECTUS PHARMACEUTICALS, INC.

                         By: /s/ Craig Dees
                             ---------------------------------
                         Name: H. Craig Dees, Ph.D.
                         Its: Chief Executive Officer


                          GRYFFINDOR CAPITAL PARTNERS I, L.L.C.

                          By: /s/ Stuart Fuchs
                              ---------------------------------
                          Name:  Stuart Fuchs
                          Its: Managing Principal


                                       8

                                                                    Exhibit 4.17

Neither this Warrant  represented  by this  certificate  nor this Warrant Shares
issuable  upon the  exercise  of this  Warrant  have been  registered  under the
Securities  Act of 1933,  as  amended  (the  "Securities  Act"),  and may not be
offered, sold or otherwise transferred, pledged or hypothecated unless and until
such shares are registered  under the Securities Act or an opinion of counsel or
other evidence,  in either case reasonably  satisfactory to the Corporation,  is
obtained to the effect that such registration is not required.

                          Common Share Purchase Warrant

                             Date: January 29, 2003
--------------------------------------------------------------------------------
                  Transfer Restricted - See Section Article IX

     Provectus Pharmaceuticals,  Inc., a Nevada corporation (the "Corporation"),
hereby certifies that, for value received,  Investor-Gate.com (the "Holder"), is
entitled,  on the terms and  subject  to the  conditions  set forth  herein,  to
purchase  from the  Corporation,  up to  Twenty-Five  Thousand  (25,000)  of the
Corporation's  Common  Shares,  as defined in Section  Section 6.4 (the "Warrant
Shares"),  at a price of  Seventy-Five  Cents  ($0.75)  per  Warrant  Share (the
"Exercise  Price").  This Warrant shall be exercisable at any time and from time
to time  during the period  beginning  on the date set forth above and ending on
the date which is 18 months  thereafter (the "Exercise  Period").  The number of
Common Shares  issuable upon the exercise of this Warrant and the Exercise Price
per share shall be subject to adjustment from time to time as set forth herein.

1.   CERTAIN DEFINITIONS

     Whenever used in this Warrant, the following terms shall have the following
meanings:

     (a)  "Affiliate"  means  any  Person  who  now or  hereafter,  directly  or
indirectly through one or more intermediaries, Controls, is Controlled by, or is
under common Control with, another Person.

     (b)  "Business  Day"  means a day other than  Saturday,  Sunday or a day on
which banks are not open for business in Knoxville, Tennessee.

     (c)  "Combination"  means an event in which  the  Corporation  consolidates
with,  merges with or into, or sells all or  substantially  all of its assets to
another Person.

     (d) "Common Shares" means the Corporation's common shares, $.001 par value.

     (e) "Control" means the possession, directly or indirectly, of the power to
direct  or cause the  direction  of the  management  and  policies  of a Person,
whether  through the  ownership  of voting  stock or  interests,  by contract or
otherwise.

     (f) "Exchange Act" means the Securities Exchange Act of 1934.

     (g)  "Person"  means  an  individual,  partnership,   corporation,  limited
liability  company,  trust,  unincorporated  organization,   association,  joint
venture or a government or agency or political subdivision thereof.

     (h) "Securities Act" means the Securities Act of 1933.

2.   EXERCISE OF WARRANT

     (a) This Warrant may be exercised,  in whole or in part, at any time during
the Exercise  Period,  by the Holder  providing  written  notice  thereof to the
Corporation,  in  the  form  attached  hereto  as  Exhibit  A  (the  "Notice  of
Exercise"),  in  accordance  with  Section  Article XII hereof,  accompanied  by
payment of the aggregate  Warrant  Price for the number of Warrant  Shares to be
purchased (i) in cash or by check,  payable to the order of the  Corporation  or
(ii)  by  wire  transfer  in  accordance  with   instructions   provided  by the
Corporation.


                                        1

     (b)  Subject to  Section  Article IX  hereof,  upon the  surrender  of this
Warrant and payment of the aggregate  Exercise Price in accordance  with Section
2(a),  the  Corporation  shall issue,  and shall  deliver to or upon the written
order of the Holder and in such name or names as the  Holder  may  designate,  a
certificate or certificates  for the number of whole Warrant Shares so purchased
(or the other securities or property to which the Holder is entitled pursuant to
Section 3 of this  Warrant),  together with cash as provided in Section  Section
2(d) in respect of any fractional  Warrant Shares  otherwise  issuable upon such
exercise.

     (c)Certificates for Warrant Shares shall be deemed to have been issued, and
any Person so  designated  to be named  therein shall be deemed to have become a
holder of record of the Warrant  Shares,  as of the date of the surrender of the
Warrant  Certificate and payment of the aggregate Exercise Price in Shares shall
be closed,  certificates  for Warrant Shares shall be issuable as of the date on
which such books next shall be opened, and until such date the Corporation shall
be  under  no  duty  to  deliver  any  certificates  for  Warrant  Shares.  Each
certificate  representing Warrant Shares shall bear the Private Placement Legend
except as otherwise provided in Section 4(c).

     (d) The  Corporation  shall not be  required  to issue  fractional  Warrant
Shares on the  exercise  of  Warrants.  If,  except for the  provisions  of this
Section  Section 2(d), any fraction of a Warrant Share would be exercisable upon
the exercise of any Warrant or specified portion thereof,  the Corporation shall
pay at the time of  exercise  an  amount  in cash  equal to such  fraction  of a
Warrant  Share,  multiplied  by the fair market  value of a Common  Share on the
Business Day prior to the date of exercise, computed to the nearest whole cent.

3.   ANTIDILUTION PROVISIONS

     (a) In the event that, at any time or from time to time after the Effective
Date, the  Corporation  (i) shall pay a dividend or make a  distribution  on the
Common  Shares  payable in Common  Shares or other  shares of the  Corporation's
capital stock, (ii) shall subdivide the outstanding  Common Shares into a larger
number of Common  Shares or other equity  securities of the  Corporation,  (iii)
shall  combine the  outstanding  Common  Shares into a smaller  number of Common
Shares or other equity securities of the Corporation,  or (iv) shall increase or
decrease the number of Common  Shares  outstanding  by  reclassification  of the
Common Shares; then:

          (A) the number of Common  Shares  issuable  upon the  exercise  of any
     Warrant  shall be a number of shares equal to the product of (I) the number
     of Common  Shares that the Holder of this Warrant  would have been entitled
     to receive if this  Warrant  had been  exercised  immediately  prior to the
     event (or, in the case of a dividend or  distribution  described  in clause
     (i)  above,  immediately  prior to the  record  date  therefor)  and (II) a
     fraction, the numerator of which shall be the total number of Common Shares
     outstanding  immediately  after the completion of the event described above
     and the  denominator  of which shall be the total  number of Common  Shares
     outstanding  immediately  prior to the  happening  of the  event  described
     above; and

          (B) subject to Section  Section  3(e),  the Exercise  Price shall be a
     price per share equal to the Exercise Price in effect  immediately prior to
     the event,  divided by the fraction  calculated in  accordance  with clause
     (A)(II) above.

     An  adjustment  made  pursuant to this Section 3(a) shall become  effective
immediately  after the effective  date of the event,  retroactive  to the record
date for the event in the case of a dividend or distribution in Common Shares or
other shares of the Corporation's capital stock.

     (b)  Except  as  provided  in  Section  Section  3(c),  in the  event  of a
Combination,  the Holder shall have the right to receive,  upon exercise of this
Warrant,  the kind and amount of shares of capital stock or other  securities or
property  which such Holder  would have been  entitled  to receive  upon or as a
result of such Combination had this Warrant been exercised  immediately prior to
the Combination. Unless Section 3(c) applies to the Combination, the Corporation
shall provide that the  surviving or acquiring  Person in the  Combination  (the
"Successor  Corporation")  will  confirm the  Holder's  rights  pursuant to this
Section 3(b) and provide for adjustments, which shall be as nearly equivalent as
may be  practicable  to the  adjustments  provided  for in this  Section  3. The
provisions of this Section 3(b) shall apply to successive Combinations involving
any Successor Corporation.

     (c) In the event of (i) a Combination in which  consideration is to be paid
to the holders of Common  Shares in exchange for their shares  solely in cash or
(ii) the dissolution, liquidation or winding-up of the Corporation, Holder shall
be entitled to receive, upon surrender of their Warrant Certificates,

                                       2

distributions  on an equal  basis with the  holders of Common  Shares,  or other
securities issuable upon the exercise of this Warrants,  as if this Warrants had
been exercised immediately prior to the event, less the aggregate Exercise Price
payable by the Holder.

     (d) In the event of a Combination  pursuant to which Holder become entitled
to receive,  upon exercise of this Warrants,  capital stock,  other  securities,
property,  cash or other distributions pursuant to Sections 3(b) or 3(c), Holder
thereafter  shall not be entitled to receive Common Shares upon exercise of this
Warrants.

     (e) The  adjustments  required by this Section 3 shall be made whenever and
as often as any specified event requiring an adjustment shall occur, except that
no adjustment of the Exercise Price or the number of Common Shares issuable upon
the  exercise of Warrants  that  otherwise  would be required to made unless and
until such adjustment, either by itself or with other adjustments not previously
made,  increases or decreases by at least 1% of the Exercise Price or the number
of Common Shares issuable upon the exercise of Warrants as in effect immediately
prior  to  the  making  of  such  adjustment  (the  "Minimum  Adjustment").  Any
adjustment smaller than the Minimum Adjustment shall be carried forward and made
as soon as such  adjustment,  together with other  adjustments  required by this
Section 3 and not  previously  made,  would result in an  adjustment at least as
large as the Minimum  Adjustment.  For the purpose of any adjustment,  except as
specified  in the final  paragraph  of  Section  3(a),  any event  requiring  an
adjustment shall be deemed to have occurred at the close of business on the date
of its  occurrence.  In computing  adjustments  under this Section 3, fractional
interests  in  Common  Shares  shall  be  taken  into  account  to  the  nearest
one-hundredth of a share.

     (f) Whenever the  Exercise  Price or the number of Common  Shares and other
securities  or property,  if any,  issuable upon the exercise of this Warrant is
adjusted pursuant to this Section 3, the Corporation shall deliver to the Holder
a certificate describing in reasonable detail the event requiring the adjustment
and the method by which the  adjustment  was  calculated  and setting  forth the
Exercise  Price and the number of Common  Shares  issuable  upon the exercise of
this Warrant after giving effect to such adjustment.

     (g) In the event that the  Corporation  shall propose (i) to pay a dividend
or make a  distribution  on the Common Shares  payable in Common Shares or other
shares  of the  Corporation's  capital  stock,  (ii) to  subdivide,  combine  or
reclassify the outstanding Common Shares, (iii) effect any reorganization of the
Corporation  or any  Combination,  (iv) to effect the  voluntary or  involuntary
dissolution,  liquidation or winding-up of the  Corporation,  or (v) to make any
tender  offer or  exchange  offer with  respect to the Common  Shares,  then the
Corporation  shall  give the  Holder  notice of such  proposed  action or offer,
specifying the record date for the action or offer and the date of participation
therein by the holders of Common  Shares,  if any such date is to be fixed,  and
briefly  describing  the effect of such  action on the Common  Shares and on the
Exercise  Price and the  number  and kind of any  other  shares of stock and the
other  property,  if any,  issuable  upon  exercise of this Warrant after giving
effect to any  adjustment  pursuant to this Section 3 that will be required as a
result of such action. Notice in accordance with the foregoing shall be given as
promptly as  possible  and in any event (A) at least 10 days prior to the record
date for the action, in the case of an action described in clause (i); or (B) at
least 20 days  prior  to the date of the  taking  of the  action  or the date of
participation therein by the holders of Common Shares,  whichever is earlier, in
the case of any other action.

4.   TRANSFER; LEGENDS

     (a) This Warrant  shall not be  transferable,  nor may it be the subject of
any sale, assignment, pledge or other conveyance.

     (b) The Warrant Shares may not be offered or sold except (i) pursuant to an
effective  registration  statement  under  the  Securities  Act or  (ii)  if the
Corporation  first shall have been furnished with an opinion of legal counsel or
other evidence,  in either case reasonably  satisfactory to the Corporation,  to
the  effect  that  such  sale  or  transfer  is  exempt  from  the  registration
requirements of the Securities Act.

     (c)  Notwithstanding the provisions of Section 4(b) of this Warrant,
no  registration  or opinion  of counsel  shall be  required  for a transfer  of
Warrant Shares made in accordance with Rule 144 under the Securities Act.

                                       3

     (d)  Except as  provided  in  Section  Section  9.5 of this  Warrant,  this
Warrant,  any Warrant issued in replacement of this Warrant and each certificate
representing  Warrant Shares issued upon exercise of this Warrant shall bear the
following legend (the "Private Placement Legend") on the face thereof:

     Neither  the  Warrants  represented  by this  certificate  nor  the  shares
     issuable upon the exercise of these Warrants have been registered under the
     Securities Act of 1933, as amended (the  "Securities  Act"), and may not be
     offered, sold or otherwise transferred,  pledged or hypothecated unless and
     until such shares are registered  under the Securities Act or an opinion of
     counsel or other evidence,  in either case  reasonably  satisfactory to the
     Corporation,  is  obtained  to the  effect  that such  registration  is not
     required.

     (e) Upon the exchange or  replacement of Warrants or Warrant Shares bearing
the Private  Placement  Legend,  the Corporation  shall deliver only Warrants or
Warrant Shares, as applicable,  that bear the Private Placement Legend,  unless:
(i) such transfer or exchange is effected pursuant to an effective  registration
statement under the Securities Act; or (ii) in the case of Warrant Shares,  such
Warrant  Shares were acquired  pursuant to an effective  registration  statement
under the  Securities  Act; or (iii) there is  delivered to the  Corporation  an
opinion  of  legal  counsel  or  other  evidence,   in  either  case  reasonably
satisfactory  to the  Corporation,  to the effect  that such sale or transfer is
exempt from the registration requirements of the Securities Act.

     (f) By its  acceptance  of this  Warrant or any Warrant  Share  bearing the
Private Placement Legend,  the Holder  acknowledges the restrictions on transfer
of this Warrant and the Warrant Shares, as applicable, set forth in this Warrant
and agrees  that it shall  transfer  this  Warrant  or the  Warrant  Shares,  as
applicable, only as provided in this Warrant.

5.   RIGHTS OF HOLDER

     Prior to the exercise of this Warrant, the Holder shall not be entitled (i)
to receive dividends or other  distributions  payable on Common Shares,  (ii) to
receive  notice of or vote at any  meeting  of the  Corporation's  stockholders,
(iii) to consent to any action of the  stockholders,  (iv) to receive  notice as
stockholders of the Corporation of any other proceedings of the Corporation, (v)
to  exercise  any  preemptive  rights,  or (vi) to  exercise  any  other  rights
whatsoever as stockholders of the Corporation.

6.   REPRESENTATIONS AND WARRANTIES OF THE CORPORATION

     The Corporation is a corporation duly incorporated, validly existing and in
good  standing  under the laws of the State of Nevada,  and has the full  right,
power and  authority to execute and deliver this Warrant and to  consummate  the
transactions contemplated hereby. The execution and delivery of this Warrant and
the  consummation  of the  transactions  contemplated  hereby have been duly and
validly authorized by all necessary action on the part of the Corporation and no
other proceedings on the part of the Corporation are necessary to authorize this
Warrant or the consummation of the transactions contemplated hereby.

7.   NOTICES

     All notices, requests, consents and other communications hereunder shall be
in writing and shall be deemed to have been made (x) upon actual  receipt,  when
given by hand or confirmed  facsimile or electronic mail  transmission,  (y) one
day after delivery to the carrier,  when given by overnight  delivery service or
(z) two days after mailing,  when given by  first-class  registered or certified
mail, postage prepaid,  return receipt  requested;  in any case to the following
address,  or to such other  address as a party,  by notice to the other  parties
given pursuant to this Section 7, may designate from time to time:

                                       4

 (a)  If to the Holder, to:

      Investor-Gate.com
      Attention: Kevin Leigh, President
      18533 Roscoe Blvd #142
      Northridge CA 91324
      Facsimile:
      email:

 (b)  If to the Corporation, to:            With a copy to:

      Provectus Pharmaceuticals, Inc.       Baker, Donelson, Bearman & Caldwell
      Attention: President                  Attention: David L. Morehous, Esq.
      7327 Oak Ridge Highway, Suite A       Riverview Tower, Suite 2200
      Knoxville, TN 37931                   900 South Gay Street
      Facsimile: 865.539.9654               Knoxville, TN 37902
      email: scott@provectuscorp.com        Facsimile: 865.525.8569
                                            Email: dmorehous@bdbc.com

8.   GOVERNING LAW; VENUE OF ACTIONS

     (a) This Warrant  shall be governed and  construed in  accordance  with the
internal laws of the State of Nevada as applied to contracts  made and performed
within the State of Nevada,  without regard to the principles  thereof regarding
resolution of conflicts of law.

     (b)  The  Corporation  and  the  Holder  each  hereby  (i)  submit  to  the
jurisdiction  of any  state  court  of  competent  jurisdiction  in and for Knox
County,  Tennessee,  or in the  United  States  District  Court for the  Eastern
District of Tennessee  sitting at Knoxville in any action or proceeding  arising
out of or relating  to this  Warrant and agree that all claims in respect of the
action or proceeding may be heard and  determined in any such court;  (ii) agree
not to bring any action or proceeding arising out of or relating to this Warrant
in any  other  court;  (iii)  waive any  defense  of  inconvenient  forum to the
maintenance  of any action or proceeding so brought and waive any bond,  surety,
or other  security  that  might be  required  of any other  Party  with  respect
thereto;  and (iv) agree that a final  judgment in any action or  proceeding  so
brought  shall be  conclusive  and may be enforced by suit on the judgment or in
any other manner provided by law or in equity.

9.   GENERAL PROVISIONS

     (a) This Warrant  embodies the entire agreement and  understanding  between
the parties  hereto with respect to the subject matter hereof and supersedes all
prior agreements and understandings relating to such subject matter.

     (b)  Except as  otherwise  expressly  set forth in this  Warrant,  any term
hereof  may be  amended  and the  observance  of any term  hereof  may be waived
(either  generally  or in a  particular  instance  and either  retroactively  or
prospectively), with the written consent of the parties hereto. No waivers of or
exceptions to any term,  condition or provision of this  Warrant,  in any one or
more instances,  shall be deemed to be, or construed as, a further or continuing
waiver of any such term, condition or provision.

     (c) The invalidity or  unenforceability  of any provision  hereof shall not
affect the validity or enforceability of any other provision hereof.

                     * Signatures appear on following page *

                                       5

                                   Signatures

     IN WITNESS  WHEREOF,  the  Corporation  has caused this  Warrant to be duly
executed and delivered as of the date first set forth above.

                                     PROVECTUS PHARMACEUTICALS, INC.,
                                     a Nevada corporation

                                     By: /s/ Timothy C. Scott
                                         -----------------------------
                                     Name: Timothy C. Scott
                                           ---------------------------
                                     Title: President
                                            --------------------------

ACCEPTED AND AGREED to as of the date first set forth above:

INVESTOR-GATE.COM

     By: /s/ Kevin Leigh
         -----------------
     Name: Kevin Leigh
           ---------------
     Title: President
            --------------

                                        6

                                                                 Exhibit 10.11.1



                                 January 8, 2003


Timothy C. Scott, Ph.D.
President
Provectus Pharmaceuticals, Inc.
7327 Oak Ridge Highway #A
Knoxville, TN   37931

Dear Mr. Scott:

     This letter agreement (the  "Agreement")  confirms the terms and conditions
of the engagement of INVESTOR-GATE.COM,  by Provectus Pharmaceuticals, Inc. (the
"Company") to render  certain  investor  relations  and financial  communication
services to the Company which are referred to herein.

     1.  Services.   INVESTOR-GATE.COM  agrees  to  perform  investor  relations
services for the Company which are  ordinarily and  customarily  performed by an
investor relations firm on behalf of a corporate client. These services include,
but are not  limited  to,  (a)  distribution  of  financial  and  general  press
releases;  (b) (if needed)  drafting of a corporate  profile for distribution to
the   Company's   shareholders   and  the  public;   (c)   Profiling   PROVECTUS
PHARMACEUTICALS (PVCT) Corporation and links to PROVECTUS PHARMACEUTICALS (PVCT)
Corporation  website  hosted  by  Investor-gate.com's   financial  website;  (d)
handling new and existing  investors through personal contact via phone, fax and
computer (e) Setting up broker presentations utilizing a variety of shows funded
by PROVECTUS PHARMACEUTICALS (PVCT) and most importantly (f) introduction of the
Company to the financial brokerage community and investors.

     2.  Non-exclusive  Relationship;  No Guarantee.  Commencing January 8, 2003
(the "Commencement Date"),  INVESTOR-GATE.COM  will act as a non-exclusive agent
of the Company and shall use its best efforts in the performance of its services
described  above.  Nothing in this  Agreement  shall be  construed  as  limiting
INVESTOR-GATE.COM's    right   to   represent   other   clients,   except   that
INVESTOR-GATE.COM agrees not to represent any other person or entity which is in
direct competition with the Company unless  INVESTOR-GATE.COM  first obtains the
Company's written consent, which shall not be unreasonably withheld.

     3. Fees.  During the  period of 90 days  after the  Commencement  Date (the
"Start-up  Period"),  the  Company  shall  pay  to  INVESTOR-GATE.COM,  for  its
services, a monthly fee of $7,250.00 per month. The monthly fee shall be paid by
the  issuance  and delivery to  INVESTOR-GATE.COM  of a number of the  Company's
common shares,  $.001 par value,  equal to the amount of the monthly fee. During
the Start-up  Period,  the value of the Company's common shares hereby is agreed
to be $0.75 per share. The monthly fees for the Start-up Period shall be prepaid
by the  Company;  the  Company  and  INVESTOR-GATE.COM  hereby  agree  that  the
Company's  obligations  shall  be  satisfied  by  the  execution  of  a  written
instruction  from the  Company or its  attorney  to the  transfer  agent for the
Company's common shares,  on or before the third business day following the date
of this  Agreement,  ordering the issuance of the  appropriate  number of common
shares to INVESTOR-GATE.COM.


     Following the end of the Start-up Period, during the term of this Agreement
the Company shall pay to  INVESTOR-GATE.COM,  for its services, a monthly fee in
the amount of $6,000. The monthly fee shall be paid by the issuance and delivery
to  INVESTOR-GATE.COM  of a number of the  Company's  common shares equal to the
amount of the monthly fee. For each month after the Start-up  Period,  the value
of the  Company's  common  shares  hereby is agreed to be the  greater of (i) an
amount per share  equal to the  average  closing  price of one of the  Company's
common  shares on the  Over-the-Counter  Bulletin  Board  (or any other  trading
system or exchange on which the Company's  common  shares may be traded)  during
the five trading days prior to the commencement of such month, or (ii) $0.75 per
share.  The  monthly  fees for each month shall be prepaid by the  Company;  the
Company and INVESTOR-GATE.COM  hereby agree that the Company's obligations shall
be satisfied by the execution of a written  instruction  from the Company or its
attorney to the transfer agent for the Company's common shares, on or before the
second  business day of each month,  ordering  the  issuance of the  appropriate
number of common shares to INVESTOR-GATE.COM.

     As additional fees, the Company shall grant to  INVESTOR-GATE.COM  warrants
for the  purchase  of common  shares in  accordance  with this  paragraph.  Upon
execution  of this  Agreement,  the  Company  will  grant  to  INVESTOR-GATE.COM
warrants for the purchase of 25,000 common shares at a price of $0.75 per share.
Upon  the   completion   of  the   Start-up   Period,   the   Company   will  to
INVESTOR-GATE.COM  warrants for the purchase of 25,000  common shares at a price
of $2.00. Upon the first anniversary of the date of this Agreement,  the Company
will grant to  INVESTOR-GATE.COM  warrants  for the  purchase  of 25,000  common
shares at a price of $5.00.  All  warrants  granted  pursuant to this  paragraph
shall expire 18 months from the date of grant.

     All of the Company's common shares issued to INVESTOR-GATE.COM  pursuant to
this  Section  3 shall be issued  pursuant  to one or more  exemptions  from the
registration  requirements  of the  Securities  Act of  1933,  as  amended,  and
applicable  state  securities  laws and shall be  "restricted  stock" within the
meaning of Rule 144 under the  Securities Act of 1933. The Company hereby grants
to  INVESTOR-GATE.COM  Piggy-Back  Rights (as  defined in Section 5 below)  with
respect to all such common shares.

     4.  Expenses.  In addition to any fees that may be payable  hereunder,  the
Company agrees, from time to time upon request,  to reimburse  INVESTOR-GATE.COM
for all reasonable out of pocket  expenses  incurred by it in the performance of
services on behalf of the Company. Such out of pocket expenses shall include any
travel on behalf of the Company.  It is  understood by  INVESTOR-GATE.COM,  that
individual expenses in excess of $200.00 (two hundred dollars) will be approved,
in advance,  by the Company in writing.  Any disputed expense must be made known
to INVESTOR-GATE.COM in writing within 5 days of receipt. Out of pocket expenses
will be  billed  on or about  the  fifteenth  of each  month and will be due and
payable with 10 days of receipt.

     5. Equity  Participation.  As an inducement for  INVESTOR-GATE.COM to enter
into this  Agreement,  the Company agrees to grant to  INVESTOR-GATE.COM  or its
successor or designee,  within 10 business  days of the date of this  Agreement,
warrants  for the purchase of 50,000  common  shares,  at an exercise  price per
share equal to the greater of (i) 50% of the average closing price of one of the
Company's  common shares on the  Over-the-Counter  Bulletin  Board (or any other
trading  system or exchange on which the Company's  common shares may be traded)
during the ten trading  days prior to the date of exercise,  or (ii) $0.75.  The
warrants   granted   pursuant   to  this   Section   5  may  be   exercised   by
INVESTOR-GATE.COM  no  earlier  than the first  anniversary  of the date of this
Agreement and no later than the second anniversary thereof;  provided, that such
warrants may be exercised  for the purchase of no more than 12,500 shares during
any  three-month  period within such period of  exercisability.  Termination  of
INVESTOR-GATE.COM's engagement hereunder shall not effect the provisions of this
Section 5 which shall survive such termination.

     The Company  shall  include the shares  issuable  upon the  exercise of the
warrants  granted  pursuant to this Section 5,  together  with any shares issued
pursuant to (or upon the exercise of warrants  granted pursuant to) Section 3 of
this Agreement,  with any of the Company's  securities it determines to register


for its own  account  at any  time,  subject  only,  in an  underwritten  public
offering,  to such customary limitations which such underwriter may impose based
upon its determination that marketing factors require a limitation on the number
of shares to be  underwritten  (the "Piggy Back Rights").  The Piggy Back Rights
shall not apply from time to time,  if, at the time such holder  desires to sell
any of the Shares,  the holder of the Shares  (together with its  affiliates) is
able to sell all such Shares  remaining  pursuant to Rule 144 promulgated  under
the  Securities  Act of 1933, as amended.  The Piggy Back Rights shall  continue
until all the Shares are registered and sold.

     6. Termination of the Engagement.  INVESTOR-GATE.COM's engagement hereunder
may be terminated by either the Company or  INVESTOR-GATE.COM  at any time, with
or  without  cause,  upon  written  advice to that  effect  to the other  party;
provided,  however, that  INVESTOR-GATE.COM will be entitled to (a) its full fee
for  the  first  One  Hundred  and  Eighty  (180)  days of the  current  program
activities  under Section 3 (with the exception of the warrant  package)  hereof
regardless of when this Agreement is terminated if terminated by the Company and
provided further,  that the provisions of this Section 6 and Sections 4, 5 and 7
hereof  shall  survive such  termination.  All warrants and options are excluded
from cancellation for 18 months from the signing of this contract.

     7. Indemnity.

        (a)    Indemnification    by   the   Company.    In   connection    with
INVESTOR-GATE.COM's  engagement  hereunder,  including  modifications  or future
additions to this engagement and the related  activities prior to this date, the
Company   agrees   that  it   will   indemnify,   hold   harmless   and   defend
INVESTOR-GATE.COM and its affiliates,  any director,  officer, agent or employee
of  INVESTOR-GATE.COM  or any of its affiliates  and each other person,  if any,
controlling  INVESTOR-GATE.COM  or any of  its  affiliates  and  each  of  their
successors and assigns (collectively, the "INVESTOR-GATE.COM Group") against and
in  respect  of any and  all  losses,  damages,  claims,  obligations,  demands,
actions, suits, proceedings, assessments, liabilities, judgments, recoveries and
deficiencies,  costs and expenses  (including,  without  limitation,  reasonable
attorneys'  fees and costs and expenses  incurred in  investigating,  preparing,
defending against or prosecuting any litigation,  claim,  proceeding or demand),
all  on an  after-tax  basis,  less  any  amounts  actually  paid  as  insurance
reimbursement,  of any kind or character  (collectively,  a "Loss"), (i) related
to,  arising out of or result from (A) oral or written  information  provided by
the Company,  the Company's  employees or the Company's other agents, for use by
INVESTOR-GATE.COM in connection with INVESTOR-GATE.COM's performance of services
under this  Agreement;  (B) other action or failure to act by the  Company,  the
Company's employees or the Company's other agents or by INVESTOR-GATE.COM at the
Company's request or with the Company's consent or (C) any breach of, or failure
by  the  Company  to  fully   perform,   or  any   inaccuracy  in,  any  of  the
representations,  warranties,  covenants  or  agreements  of the Company in this
Agreement  or (ii)  otherwise  related to or arising  out of the  engagement  of
INVESTOR-GATE.COM  pursuant to this  Agreement or any  transaction or conduct in
connection  therewith except that this clause (ii) and clause (i)(B) relating to
actions by  INVESTOR-GATE.COM,  shall not apply with  respect to any losses that
are   finally   judicially   determined   to  have   resulted   primarily   from
INVESTOR-GATE.COM's bad faith or gross negligence.

        (b) Notice of Claim. Whenever  INVESTOR-GATE.COM  learns of or discovers
any  matter  which may give rise to a claim for  indemnification  (the  "Claim")
against the  Company  under this  Section 7 (the  "Indemnity  Obligor"),  as the
indemnified party (the "Indemnified Party"),  shall give notice to the Indemnity
Obligor of the Claim.  With  respect to Claims which are the subject of actions,
suits,  or  proceedings  threatened or asserted in writing by any third party (a
"Third Party  Claim"),  the  Indemnified  Party shall,  within 15 days following
receipt of such Third Party  Claim,  promptly  notify the  Indemnity  Obligor in
writing of any Claim for recovery, specifying in reasonable detail the nature of
the Loss and the amount of the liability  estimated to arise  therefrom.  If the
Indemnified Party does not so notify the Indemnity Obligor within 15 days of its
discovery of a Third Party Claim,  such Claim shall be barred only to the extent


that the  Indemnity  Obligor  is  prejudiced  by such  failure  to  notify.  The
Indemnified  Party  shall  provide  to the  Indemnity  Obligor  as  promptly  as
practicable thereafter all information and documentation reasonably requested by
the Indemnity Obligor to verify the Claim asserted.

        (c)  Defense.  If the facts  relating  to a Loss arise out a Third Party
Claim, or if there is any claim against a third party available by virtue of the
circumstances of the Loss, the Indemnity Obligor shall, by giving written notice
to the  Indemnified  Party within 15 days following its receipt of the notice of
such  claim,  assume  the  defense or the  prosecution  thereof,  including  the
employment of counsel or accountants, reasonably satisfactory to the Indemnified
Party, at its cost and expense;  provided,  however, that during the interim the
Indemnified  Party shall use its best efforts to take all action (not  including
settlement)  reasonably necessary to protect against further damage or loss with
respect  to the  Loss.  The  Indemnified  Party  shall  have the right to employ
counsel  separate  from counsel  employed by the  Indemnity  Obligor in any such
action and to  participate  therein,  but the fees and  expenses of such counsel
shall be at the  Indemnified  Party's  own  expense,  unless (a) the  employment
thereof has been  specifically  authorized  by the Indemnity  Obligor,  (b) such
Indemnified  Party has been advised by counsel  reasonably  satisfactory  to the
Indemnity  Obligor that there may be one or more legal defenses  available to it
which are  different  from or  additional  to those  available to the  Indemnity
Obligor and in the reasonable  judgment of such counsel it is advisable for such
Indemnified Party to employ separate  counsel,  or (c) the Indemnity Obligor has
failed to assume the  defense  of such  action  and  employ  counsel  reasonably
satisfactory  to the  Indemnified  Party.  Whether or not the Indemnity  Obligor
defends or prosecutes such claim,  all the parties hereto shall cooperate in the
defense or prosecution  thereof and shall furnish such records,  information and
testimony and shall attend such conferences,  discovery proceedings and trial as
may be reasonably requested in connection therewith. The Indemnity Obligor shall
not be liable for any  settlement of any such claim  effected  without its prior
written  consent.  In the  event of  payment  by the  Indemnity  Obligor  to the
Indemnified  Party in  connection  with any Loss  arising  out of a Third  Party
Claim, the Indemnity Obligor shall be subrogated to and shall stand in the place
of the Indemnified  Party as to any events or  circumstances in respect of which
the  Indemnified  Party may have any right or claim  against  such  third  party
relating to such indemnified  matter. The Indemnified Party shall cooperate with
the Indemnity Obligor in prosecuting any subrogated claim. The Indemnity Obligor
will take no action in connection with any claim that would adversely affect the
Indemnified Party without the consent of the Indemnified Party.

        (d)  Duration of the  Company's  Obligations.  The  Indemnity  Obligor's
indemnification  obligations  under this Agreement shall survive the termination
of this Agreement.

     8. Acknowledgments and Representations.

        (a) The Company  recognizes  and confirms that in performing  its duties
pursuant to this  Agreement,  INVESTOR-GATE.COM  will be using and relying  upon
data, material and other information furnished by the Company, its employees and
representatives  (the  "Information").  The Company hereby agrees and represents
that all  Information  furnished to  INVESTOR-GATE.COM  in connection  with this
Agreement  shall be accurate and  complete in all material  respects at the time
furnished,  and that if such Information,  in whole or part,  becomes materially
inaccurate,  misleading  or  incomplete  during the term of  INVESTOR-GATE.COM's
engagement hereunder,  the Company shall so advise  INVESTOR-GATE.COM in writing
and  correct  any such  inaccuracy  or  omission.  INVESTOR-GATE.COM  assumes no
responsibility  for  the  accuracy  and  completeness  of such  Information.  In
rendering its services hereunder, INVESTOR-GATE.COM shall be entitled to use and
rely upon the  Information  without  independent  verification  thereof.  To the
extent  consistent with legal  requirements,  all  Information,  unless publicly
available or otherwise  available to  INVESTOR-GATE.COM  without  restriction or
breach of any confidentiality  agreement,  will be held by  INVESTOR-GATE.COM in
confidence  and will not be disclosed  to anyone other than  INVESTOR-GATE.COM's
agents and advisors without the Company's prior written approval or used for any
purpose other than those referred to in this Agreement.


        (b) The Company  understands  and agrees that in furnishing  the Company
with  advice  and  other  services  as  provided  in  this  Agreement,   neither
INVESTOR-GATE.COM nor any officer,  director or agent thereof shall be liable to
the Company,  its affiliates or its creditors for errors of judgment or anything
except bad faith or gross  negligence in the performance of its duties under the
terms of this Agreement.

        (c) The Company  acknowledges that  INVESTOR-GATE.COM  has been retained
solely as an  advisor to the  Company,  and not as an advisor to or agent of any
other person,  and that the Company's  engagement  of  INVESTOR-GATE.COM  is not
intended  to  confer  rights  upon any  persons  not a party  hereto  (including
shareholders,    employees   or   creditors   of   the   Company)   as   against
INVESTOR-GATE.COM, INVESTOR-GATE.COM's affiliates or their respective directors,
officers, agents and employees.

        (d) The Company  represents  and warrants to  INVESTOR-GATE.COM  that it
will not cause, or knowingly permit (a) any action to be taken which violates or
(b) a  failure  to act,  the  effect of which  violates,  any  federal  or state
securities law.

     9. Notices. All notices, requests,  consents and other communications under
this  Agreement  shall be in writing  and shall be  delivered  by hand or fax or
mailed by overnight  courier or first class certified or registered mail, return
receipt requested, postage prepaid and properly addressed as follows:

    If to INVESTOR-GATE.COM, to:       INVESTOR-GATE.COM
                                       Attention: Kevin Leigh, President
                                       18533 Roscoe Blvd #142
                                       Northridge CA 91324
                                       Fax:

    If to the Company, to:             Provectus Pharmaceuticals, Inc.
                                       Attention: Timothy C. Scott, Ph.D.,
                                       President
                                       7327 Oak Ridge Highway, Suite A
                                       Knoxville, TN 37931
                                       Fax: 865/539-9654

                                       with a copy to:
                                       Baker, Donelson, Bearman & Caldwell, P.C.
                                       Attention: David L. Morehous, Esq.
                                       2200 Riverview Tower, 900 S. Gay Street
                                       Knoxville, TN 37902
                                       Fax: 865/525-8569

          Any party may change its address  for  purposes of this  provision  by
giving the other party written notice of the new address in the manner set forth
above.  Notice will be  conclusively  deemed to have been given when  personally
delivered,  or if given by mail, on the second day after being sent by overnight
courier  or on the third day after  being  sent by first  class,  registered  or
certified  mail,  or if given  by fax,  when  confirmation  of  transmission  is
indicated by the sender's fax machine.

     10.  Arbitration.  All controversies,  disputes or claims arising out of or
relating  to this  Agreement  shall be  resolved  by  binding  arbitration.  The
arbitration  shall be conducted in accordance  with the  Commercial  Arbitration
Rules of the American  Arbitration  Association.  All arbitrators  shall possess
such  experience  in, and knowledge of, the subject area of the  controversy  or

claim so as to qualify as an "expert" with respect to such subject  matter.  The
governing law for the purposes of any arbitration  arising hereunder shall be as
set forth in  Section 11 hereof.  The  prevailing  party  shall be  entitled  to
receive  its  reasonable   attorney's   fees  and  all  costs  relating  to  the
arbitration. Any award rendered by arbitration shall be final and binding on the
parties,  and  judgment  thereon  may be  entered  in  any  court  of  competent
jurisdiction.

     11.  Governing  Law. This  Agreement  shall be governed by and construed in
accordance  with the laws of the  state of  California,  without  regard  to the
conflicts of laws provisions thereof,  and may not be amended or modified except
in writing signed by both parties.

     12.  Successors.  This Agreement and all rights and obligations  thereunder
shall be binding upon and inure to the benefit of each party's  successors,  but
may not be assigned without the prior written consent of the other party,  which
shall not be unreasonably withheld or delayed.

     13. Severability.  If any provision of this Agreement shall be held or made
invalid by a statute, rule, regulation, decision of a tribunal or otherwise, the
remainder of this Agreement  shall not be affected  thereby and, to this extent,
the provisions of this Agreement shall be deemed severable.

     14.  Authorization.  The Company  represents  and warrants  that it has all
requisite power and authority, and has received all necessary authorizations, to
enter into and carry out the terms and provisions of this Agreement.

          Please  confirm that the foregoing  correctly sets forth our Agreement
by signing the enclosed  letter in the space  provided and returning  them to us
for execution, whereupon we will send you a fully executed original letter which
shall constitute a binding Agreement as of the date first above written. We look
forward to working with you on this assignment.

                                            Very truly yours,

                                            INVESTOR-GATE.COM

                                            By: /s/ Kevin Leigh
                                                --------------------
                                                    Kevin J. Leigh
                                                    President and CEO

Agreed to and Accepted as of the date above.

Provectus Pharmaceuticals, Inc.

By: /s/ Timothy C. Scott
    -----------------------------
        Timothy C. Scott, Ph.D.
        President


                                                                 Exhibit 10.11.2


                  [PROVECTUS PHARMACEUTICALS, INC. LETTERHEAD]

February 28, 2003


Kevin Leigh
Investor-Gate.com
9857 Rathburn Avenue
Northridge, CA 91325

Dear Mr. Leigh:

Pursuant  to Section 6 of the letter  agreement  dated  January 8, 2003  between
Provectus Pharmaceuticals, Inc. ("Provectus") and Investor-Gate.com (the "Letter
Agreement"),  you hereby are advised that  Provectus is  terminating  the Letter
Agreement, effective upon your receipt of this letter.

Provectus   is   exercising   its   termination    rights   as   a   result   of
Investor-Gate.com's   failure  to  perform  the  investor   relations   services
identified in the Letter Agreement.  For that reason,  and  notwithstanding  the
provisions of Section 6 of the Letter Agreement:

     1.   Provectus hereby  terminates the warrant granted to  Investor-Gate.com
          pursuant to Section 5 of the Letter Agreement.

     2.   Effective  as of the date  hereof,  Provectus  terminates  payment  to
          Investor-Gate.com  of the  monthly  fees  provided in Section 3 of the
          Letter  Agreement;   provided,  however,  that  Provectus  will  grant
          Investor-Gate.com  the  warrants  specified in Section 3 of the Letter
          Agreement (for the purchase of (a) 25,000 common shares at an exercise
          price $0.75,  (b) 25,000 common shares at an exercise  price of $2.00,
          and (c) 25,000 common shares at an exercise price of $5.00).

Except with respect to the warrant  granted  pursuant to Section 5 of the Letter
Agreement, Investor-Gate.com may retain any fees previously paid by Provectus to
Investor-Gate.com.

Very truly yours,

/s/ Craig Dees
-----------------------
Craig Dees, Ph.D.
Chief Executive Officer


                                                                   Exhibit 10.12

                [Strategic Growth International, Inc. Letterhead]


February 20, 2003



Mr. Craig Dees
Chief Executive Officer
Provectus Pharmaceuticals, Inc.
7327 Oak Ridge Highway
Suite A
Knoxville, TN  37931

Dear Mr. Dees:

This letter will serve as an agreement between Provectus  Pharmaceuticals,  Inc.
("the Company") and Strategic Growth International, Inc. ("SGI").

DUTIES:

As Investor Relations Consultants, SGI will:

          a)   Consult with the management of the Company on Investor  Relations
               aspects of shareholder  communications,  including  arranging and
               conducting  meetings with the professional  investment  community
               and  investor  groups;  communicating  the  corporate  message to
               specified  audiences,   and  enhancing  relations  with  security
               analysts and the financial press.

          b)   Help develop and  implement a  comprehensive  Investor  Relations
               program. The program will be designed to achieve results-oriented
               goals and objectives.

          c)   Provide professional staff services as may be reasonably required
               to help the Company carry out its programs and objectives.

The scope of SGI's  services  shall not  include  any  activities  related to or
regarding the raising of funds.  Such activities,  if any, shall be subject to a
separate agreement.

LIABILITY:

The Company agrees to indemnify and hold harmless SGI from and against any and
all losses, claims, damages, expenses or liabilities which SGI may incur based
upon information, representations, reports or data furnished by the Company to
the extent that such material is furnished, prepared or approved by Provectus
Pharmaceuticals, Inc. for use by SGI.

OUT OF POCKET EXPENSES

The Company will reimburse SGI for all reasonable  out-of-pocket  disbursements,
including  travel  expenses,  made in the  performance  of its duties under this
agreement.  Items, such as luncheons with the professional investment community,
graphic design and printing, postage, long distance telephones calls, etc., will
be billed as incurred.

RECORDS AND RECORDING KEEPING

SGI will maintain accurate records of all out-of-pocket expenditures incurred on
behalf of the Company. Authorization for projects and operating activities will
be obtained in advance before commitments are made.

TERMS OF PAYMENT

Billing will be done monthly for the coming month, with the first month payable
in advance. Expenses and charges will be included in the following month's bill.

Payment is due within ten (10) days upon receipt of invoice.

SERVICE FEES

The Company will pay SGI a monthly  retainer fee of $8,000.00 for services under
this  agreement.  At the  option  of the  company,  $5,000  of such fee shall be
payable  in cash plus  30,000  shares of stock per month for the first 3 months.
The monthly  retainer  shall  commence  on  February  20, 2003 and extend for 12
months. The first monthly fee shall be payable in advance.

In addition, immediately upon execution of this agreement, the Company agrees to
grant SGI  warrants to purchase  360,000  shares of the  Company's  common stock
exercisable at the following prices:  120,000 shares at $0.25, 120,000 shares at
$0.35,  and  120,000  shares  at  $0.50.  Such  options  will be of a  five-year
duration.  At the option of SGI,  such  options may be  exercised  on a cashless
basis and will have piggy-back  registration rights for one year with respect to
the  options  with  demand  registration  rights  after  one  year,  and  may be
transferred  in whole or in part to one or more  officers of the  Company.  Such
options will be vested immediately.

TERMS OF AGREEMENT

This  agreement  is to extend from  February 20, 2003 for a period of 12 months.
The Company shall first have the right to terminate this agreement on August 20,
2003,  upon 10 days prior written  notice.  Upon such  termination on August 20,
2003, the Company will have the right to rescind 180,000 of the 360,000 options.
Sixty thousand  (60,000) of the options rescinded will be the options granted at
$0.25,  60,000 of the options  will be the  options  granted at $0.35 and 60,000
from the options granted at $0.50.

This agreement  shall be governed by and subject to the  jurisdiction of and law
of New York State.

Please  confirm  agreement  to the above by  endorsing  all three (3) copies and
returning two (2) copies to SGI.


AGREED TO AND ACCEPTED BY:

/s/ Craig Dees                                       Date:    February 20, 2003
--------------------------------
Provectus Pharmaceuticals, Inc.



/s/                                                  Date:    February 20, 2003
-------------------------------------
Strategic Growth International, Inc.


                                                                  Exhibit 10.13

                    [Josephberg Grosz & Co., Inc. Letterhead]



                                 March 27, 2003



Craig Dees, Ph.D., CEO
Provectus Pharmaceuticals, Inc.
7327 Oak Ridge Highway
Knoxville, TN 37931

Dear Craig:

     I. The  purpose of this  letter is to set forth the terms of our  agreement
(the "Agreement") with respect to the compensation which Josephberg Grosz & Co.,
Inc.  or their  designees  ("JGC")  are to receive for  assisting  and  advising
Provectus  Pharmaceuticals,  Inc. or related  entities,  direct or indirect (the
"Company"),  in obtaining a capital infusion of equity,  debt, bridge financing,
merger and  acquisitions,  letter or line of credit,  lease  financing  or other
types of financial  transactions,  including any transactions of financial value
(the  "Financing").  Our focus will be on providing  the Company with equity for
working capital needs and the finalization of its Business Plan.

     II. To assist the Company in  obtaining  Financing,  the Company  agrees to
engage  JGC as its  agent  with  respect  to all  Financing  sources,  direct or
indirect, (the "Investor").  When such Financing from any Investor introduced to
the  Company,  (other  than a  Financing  in the  nature  of  one  described  in
paragraphs  III and IV  below)  is  provided,  JGC  will be  compensated  by the
Company, in full, at the closing of the Financing, by receiving a total cash fee
of 7%, the fee due JGC when received by the Company and equal to the total gross
dollar value received or to be received  (including any form of equity,  bridge,
stock,  warrant  conversion,   convertible   securities,   convertible  debt  or
subordinated  debt  Financing)  by  the  Company  (i.e.,   $1,500,000  Financing
provided;  JG  Capital,  Inc.  receives  a cash fee of 7%, to be  $105,000).  In
addition, JGC will have the right to invest in the Company by receiving,  at the
closing of the  Financing,  a five year warrant.  Such warrant shall give JGC or
its  designees  the  right,  at any time over a five year  period,  to  purchase
securities  on a cashless  basis in the Company  equal to 8% of the total shares
issued to the Investor at the same price,  JGC's designees  receive  warrants to
purchase  shares of the same type securities and the same rights as the Investor
(i.e.,  $1,500,000  Financing  provided,  JGC's  designees  receive  warrants to
purchase  shares of the same type securities and at the same price and valuation
as the Investor at the time of  Financing  at anytime over a five year  period).
Any and all securities  and/or warrants and securities  underlying such warrants
to be received by JGC and its designees  shall have  appropriate  piggy-back and
registration  rights and in any case become free trading  immediately  following
144 holding period.

     III. For senior debt, credit  facilities,  guarantees;  lease financing and
letter or line of credit  Financing,  JGC's cash fee,  if such is provided by an
Investor  introduced  by JGC, and accepted by the Company,  shall be 3.0% of the
total dollar value received by the Company.  (All debt with convertible features
or warrants shall fall under fees in Paragraph 11 above.)

     IV. In the event the  Company  enters into a merger,  acquisition  or joint
venture  with an Investor or entity  introduced  by JGC or entities or Investors
negotiated  with on behalf of the Company by JGC, JGC will be compensated by the
Company,  in full, at the closing thereof, in accordance with the 5/4/3 Formula,
(i.e.,  by receiving a cash fee of 5% of the first  $1,000,000 of Value received
by the  Company  or the  Investor,  whichever  is  applicable,  4% of the second
$1,000,000, and 3% of all Value received in excess of $2,000,000). While not all
inclusive,  Value shall  include total cash,  notes,  debt,  stock,  consulting,
non-compete, earn-out, sales and royalty agreements.

     V. The fees in paragraphs  II, III and IV above are totally  independent of
one another and are based upon the type or types of transactions JGC arranges.

     VI. Upon the  execution  of this  Agreement,  the Company  agrees to pay JG
Capital, Inc. an engagement fee of $6,500,000 and 35,000 shares of the company's
common stock.

     VII. This  Agreement may be terminated or amended by the Company sixty days
from the signing of this  Agreement  or anytime  thereafter  with ten days prior
written  notice.  Termination of this Agreement shall not release the Company of
its obligation to compensate JGC or its designees for its services  rendered per
this Agreement. In other words, JGC shall be compensated if any party introduced
to the Company  per  paragraphs  II, II and IV,  enters  into a  transaction  or
provides  Financing  as  long as the  transaction  (transactions)  or  Financing
(Financings)  was  provided or committed  to by those  parties  within 24 months
after termination of this Agreement.

     VIII. It is  understood  and agreed that you shall have the right to accept
or reject in your judgment the terms of any Financing or transaction proposed by
any  Financing  Sources,  Investors,   strategic  partners  and/or  corporations
presented  to you. If such  Financing is provided by the Investor to the Company
and accepted,  as a condition to the closing, the company agrees to represent to
JGC, to the Investor and the Company's  and  Investors'  attorneys  prior to the
closing of the  transaction  or Financing  that the cash portion of the fees due
and payable to JGC as they apply to this  Agreement  will be paid to JG Capital,
Inc. by wire  transfer  or  certified  check at the  closing of the  transaction
and/or  Financing along with any and all other fees due JGC (stock,  etc.).  The
Company  also  agrees to copy JGC  promptly  on all  correspondence  between all
prospective  Investors  and  the  Company  and  provide  a copy  of all  closing
documents to JGC at closing.

     IX. This Agreement  shall be governed and construed in accordance  with the
laws of the State of New York. In the event of any dispute  between us regarding
the  subject  matter of this  Agreement,  such  dispute  shall be  submitted  to
arbitration  before a single  arbitrator in New York City in accordance with the
rules of the American  Arbitration  Association.  Any decision or award shall be
final and binding upon the parties  hereto.  All legal fees,  arbitration  fees,

filing fees,  collection fees, expenses and the maximum interest rate allowed by
law shall be paid to the  prevailing  party by the losing  party.  If you are in
Agreement to the foregoing, please sign and date below.

                                   Sincerely,
                                   Josephberg Grosz & Co., Inc.


                                   By: /s/ Richard A. Josephberg 3/27/03
                                       ---------------------------------
                                       Richard A. Josephberg      Date
                                       Chairman


AGREED AND ACCEPTED:

Provectus Pharmaceuticals, Inc.

By:  /s/ Craig Dees                         Date: 3/28/03
     --------------------------             --------------
     Craig Dees, Ph.D.
     CEO



                                                                    Exhibit 99.1


                 Certification Pursuant to 18 U.S.C. ss. 1350*


     Pursuant  to  18  U.S.C.ss.   1350,  as  enacted  by  Section  906  of  the
Sarbanes-Oxley Act of 2002 (Public Law 107-204), the undersigned, H. Craig Dees,
the  Chief  Executive  Officer  of  Provectus  Pharmaceuticals,  Inc.,  a Nevada
corporation (the "Company"), hereby certifies that:

     (1) The  Company's  Quarterly  Report on Form 10-QSB for the quarter  ended
March 31, 2003, as filed with the U.S. Securities and Exchange Commission on the
date hereof (the  "Report"),  fully  complies with the  requirements  of Section
13(a) or 15(d) of the Securities Exchange Act of 1934; and

     (2)  The  information  contained  in the  Report  fairly  presents,  in all
material  respects,  the  financial  condition  and results of operations of the
Company.

     This Certification is signed on May 9, 2003.

                                         /s/H. Craig Dees
                                         -------------------------------
                                         H. Craig Dees
                                         Chief Executive Officer
                                         Provectus Pharmaceuticals, Inc.

                                         /s/Daniel R. Hamilton
                                         -------------------------------
                                         Daniel R. Hamilton
                                         Chief Financial Officer
                                         Provectus Pharmaceuticals, Inc.



     A signed  original of this  written  statement  required by Section 906 has
been  provided  to  Provectus  Pharmaceuticals,  Inc.  and will be  retained  by
Provectus  Pharmaceuticals,  Inc. and furnished to the  Securities  and Exchange
Commission or its staff upon request.


Enacted by Section 906 of the Sarbanes-Oxley Act of 2002, Public Law 107-204.