1. Title of Derivative Security (Instr. 4) |
2. Date Exercisable and Expiration Date (Month/Day/Year) |
3. Title and Amount of Securities Underlying Derivative Security (Instr. 4) |
4. Conversion or Exercise Price of Derivative Security |
5. Ownership Form of Derivative Security: Direct (D) or Indirect (I) (Instr. 5) |
6. Nature of Indirect Beneficial Ownership (Instr. 5) |
Date Exercisable |
Expiration Date |
Title |
Amount or Number of Shares |
Series B-1' Preferred Stock
|
Â
(1)
|
Â
(1)
|
Common Stock
|
10,426
|
$
(1)
|
I
|
See Footnote
(2)
|
Series C' Preferred Stock
|
Â
(1)
|
Â
(1)
|
Common Stock
|
2,488,171
|
$
(1)
|
I
|
See Footnote
(3)
|
Series D' Preferred Stock
|
Â
(1)
|
Â
(1)
|
Common Stock
|
1,759,381
|
$
(1)
|
I
|
See Footnote
(4)
|
Series E Preferred Stock
|
Â
(1)
|
Â
(1)
|
Common Stock
|
1,423,566
|
$
(1)
|
I
|
See Footnote
(5)
|
Warrant (Right to Buy)
|
06/24/2011 |
06/24/2016 |
Common Stock
|
54,752
|
$
0.0913
|
I
|
See Footnote
(6)
|
Warrant (Right to Buy)
|
10/22/2012 |
10/22/2022 |
Common Stock
|
513,281
|
$
0.0913
|
I
|
See Footnote
(7)
|
Warrant (Right to Buy)
|
03/28/2013 |
03/28/2022 |
Common Stock
|
513,281
|
$
0.0913
|
I
|
See Footnote
(7)
|
Warrant (Right to Buy)
|
12/16/2014 |
12/16/2024 |
Common Stock
|
355,889
|
$
9.132
|
I
|
See Footnote
(8)
|
* |
If the form is filed by more than one reporting person, see Instruction 5(b)(v). |
** |
Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). |
(1) |
Each share of Series B-1' Preferred Stock, Series C' Preferred Stock, Series D' Preferred Stock and Series E Preferred Stock is convertible into 0.109505 of a share of Common Stock without payment of further consideration and will automatically convert into 0.109505 of a share of Common Stock immediately prior to the closing of the Issuer's initial public offering without payment of further consideration. The shares have no expiration date. |
(2) |
The shares are held as follows: 9,773 by MPM BioVentures IV-QP, L.P. ("BV IV QP"), 376 by MPM BioVentures IV GmbH & Co. Beteiligungs KG ("BV IV KG") and 277 by MPM Asset Management Investors BV4 LLC ("AM BV4"). MPM BioVentures IV GP LLC ("BV GP LLC") and MPM BioVentures IV LLC ("BV LLC") are the direct and indirect general partners of BV IV QP and BV IV KG and BV LLC is the manager of AM BV4. The Reporting Person is a member of BV LLC. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |
(3) |
The shares are held as follows: 1,479,910 by BV IV QP, 57,016 by BV IV KG, 42,083 by AM BV4 and 909,162 by MPM Bio IV NVS Strategic Fund, L.P. ("BV IV SF"). BV GP LLC and BV LLC are the direct and indirect general partners of BV IV SF. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |
(4) |
The shares are held as follows: 1,539,486 by BV IV QP, 59,313 by BV IV KG, 43,776 by AM BV4 and 116,806 by BV IV SF. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |
(5) |
The shares are held as follows: 939,089 by BV IV QP, 36,179 by BV IV KG, 26,704 by AM BV4 and 421,594 by BV IV SF. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |
(6) |
The warrants are held as follows: 51,316 by BV IV QP, 1,977 by BV IV KG and 1,459 by AM BV4. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |
(7) |
The warrants are held as follows: 481,068 by BV IV QP, 18,534 by BV IV KG and 13,679 by AM BV4. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |
(8) |
The warrants are held as follows: 234,772 by BV IV QP, 9,044 by BV IV KG, 6,675 by AM BV4 and 105,398 BV IV SF. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein. |