UNITED STATES
                    SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C. 20549

                                FORM N-CSR

          CERTIFIED SHAREHOLDER REPORT OF REGISTERED MANAGEMENT
                           INVESTMENT COMPANIES


Investment Company Act file number 811-09191

Name of Fund:  MuniHoldings Insured Fund II, Inc.

Fund Address:  P.O. Box 9011
               Princeton, NJ  08543-9011

Name and address of agent for service:  Robert C. Doll, Jr., Chief Executive
         Officer, MuniHoldings Insured Fund II, Inc., 800 Scudders Mill Road,
         Plainsboro, NJ, 08536.  Mailing address:  P.O. Box 9011, Princeton,
         NJ, 08543-9011

Registrant's telephone number, including area code:  (609) 282-2800

Date of fiscal year end: 09/30/05

Date of reporting period: 10/01/04 - 09/30/05

Item 1 -   Report to Stockholders


MuniHoldings
Insured Fund II, Inc.


Annual Report
September 30, 2005


(BULL LOGO) Merrill Lynch Investment Managers
www.mlim.ml.com


Mercury Advisors
A Division of Merrill Lynch Investment Managers
www.mercury.ml.com


MuniHoldings Insured Fund II, Inc. seeks to provide shareholders with current
income exempt from federal income taxes by investing primarily in a portfolio
of long-term, investment grade municipal obligations the interest on which, in
the opinion of bond counsel to the issuer, is exempt from federal income taxes.

This report, including the financial information herein, is transmitted to
shareholders of MuniHoldings Fund II, Inc. for their information. It is not a
prospectus. Past performance results shown in this report should not be
considered a representation of future performance. The Fund has leveraged its
Common Stock and intends to remain leveraged by issuing Preferred Stock to
provide the Common Stock shareholders with a potentially higher rate of
return. Leverage creates risks for Common Stock shareholders, including the
likelihood of greater volatility of net asset value and market price of shares
of the Common Stock, and the risk that fluctuations in the short-term dividend
rates of the Preferred Stock may affect the yield to Common Stock shareholders.
Statements and other information herein are as dated and are subject to change.

A description of the policies and procedures that the Fund uses to determine
how to vote proxies relating to portfolio securities is available (1) without
charge, upon request, by calling toll-free 1-800-MER-FUND (1-800-637-3863);
(2) at www.mutualfunds.ml.com; and (3) on the Securities and Exchange
Commission's Web site at http://www.sec.gov. Information about how the
Fund voted proxies relating to securities held in the Fund's portfolio
during the most recent 12-month period ended June 30 is available (1) at
www.mutualfunds.ml.com; and (2) on the Securities and Exchange Commission's
Web site at http://www.sec.gov.


MuniHoldings Insured Fund II, Inc.
Box 9011
Princeton, NJ
08543-9011


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MuniHoldings Insured Fund II, Inc.


The Benefits and Risks of Leveraging


MuniHoldings Insured Fund II, Inc. utilizes leveraging to seek to enhance the
yield and net asset value of its Common Stock. However, these objectives
cannot be achieved in all interest rate environments. To leverage, the Fund
issues Preferred Stock, which pays dividends at prevailing short-term interest
rates, and invests the proceeds in long-term municipal bonds. The interest
earned on these investments, net of dividends to Preferred Stock, is paid to
Common Stock shareholders in the form of dividends, and the value of these
portfolio holdings is reflected in the per share net asset value of the Fund's
Common Stock. However, in order to benefit Common Stock shareholders, the
yield curve must be positively sloped; that is, short-term interest rates must
be lower than long-term interest rates. At the same time, a period of
generally declining interest rates will benefit Common Stock shareholders. If
either of these conditions change, then the risks of leveraging will begin to
outweigh the benefits.

To illustrate these concepts, assume a fund's Common Stock capitalization of
$100 million and the issuance of Preferred Stock for an additional $50 million,
creating a total value of $150 million available for investment in long-term 
municipal bonds. If prevailing short-term interest rates are approximately 3% 
and long-term interest rates are approximately 6%, the yield curve has a 
strongly positive slope. The fund pays dividends on the $50 million of 
Preferred Stock based on the lower short-term interest rates. At the same time,
the fund's total portfolio of $150 million earns the income based on long-term
interest rates. Of course, increases in short-term interest rates would reduce
(and even eliminate) the dividends on the Common Stock.

In this case, the dividends paid to Preferred Stock shareholders are
significantly lower than the income earned on the fund's long-term investments,
and therefore the Common Stock shareholders are the beneficiaries of the
incremental yield. However, if short-term interest rates rise, narrowing the
differential between short-term and long-term interest rates, the incremental
yield pickup on the Common Stock will be reduced or eliminated completely. At
the same time, the market value of the fund's Common Stock (that is, its 
price as listed on the New York Stock Exchange) may, as a result, decline.
Furthermore, if long-term interest rates rise, the Common Stock's net asset
value will reflect the full decline in the price of the portfolio's
investments, since the value of the fund's Preferred Stock does not fluctuate.
In addition to the decline in net asset value, the market value of the fund's
Common Stock may also decline.

As a part of its investment strategy, the Fund may invest in certain
securities whose potential income return is inversely related to changes in a
floating interest rate ("inverse floaters"). In general, income on inverse
floaters will decrease when short-term interest rates increase and increase
when short-term interest rates decrease. Investments in inverse floaters may
be characterized as derivative securities and may subject the Fund to the
risks of reduced or eliminated interest payments and losses of invested
principal. In addition, inverse floaters have the effect of providing
investment leverage and, as a result, the market value of such securities will
generally be more volatile than that of fixed rate, tax-exempt securities. To
the extent the Fund invests in inverse floaters, the market value of the
Fund's portfolio and net asset value of the Fund's shares may also be more
volatile than if the Fund did not invest in these securities. As of September
30, 2005, the percentage of the Fund's total net assets invested in inverse
floaters was 7.45%, before the deduction of Preferred Stock.


Swap Agreements


The Fund may invest in swap agreements, which are over-the-counter contracts
in which one party agrees to make periodic payments based on the change in
market value of a specified bond, basket of bonds, or index in return for
periodic payments based on a fixed or variable interest rate or the change in
market value of a different bond, basket of bonds or index. Swap agreements
may be used to obtain exposure to a bond or market without owning or taking
physical custody of securities. Swap agreements involve the risk that the
party with whom the Fund has entered into the swap will default on its
obligation to pay the Fund and the risk that the Fund will not be able to meet
its obligations to pay the other party to the agreement.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



A Letter From the President


Dear Shareholder


Amid what we've coined a "muddle through" year for the financial markets, the
major benchmark indexes managed to post positive results for the current
reporting period:




Total Returns as of September 30, 2005                                    6-month        12-month
                                                                                   
U.S. equities (Standard & Poor's (S&P) 500 Index)                          +5.02%        +12.25%
Small-cap U.S. equities (Russell 2000 Index)                               +9.21%        +17.95%
International equities (MSCI Europe Australasia Far East Index)            +9.26%        +25.79%
Fixed income (Lehman Brothers Aggregate Bond Index)                        +2.31%        + 2.80%
Tax-exempt fixed income (Lehman Brothers Municipal Bond Index)             +2.80%        + 4.05%
High yield bonds (Credit Suisse First Boston High Yield Index)             +2.82%        + 6.31%


Since June 2004, the Federal Reserve Board (the Fed) has tirelessly advanced
its interest rate hiking program, raising the federal funds rate 11 times to
3.75% by period-end. The Fed admittedly remains more concerned about inflation
than slowing economic growth, causing some to worry that the central bank may
overreact to inflation and increase interest rates more than is necessary to
maintain a healthy economic balance. Recent disruptions to production and
spending from Hurricanes Katrina and Rita are likely to distort the economic
data in the short term, muddying the underlying trends. However, any hurricane-
induced slowdown is likely to be short lived, and the fiscal stimulus
associated with reconstruction efforts in the Gulf could add to gross domestic
product growth in 2006.

U.S. equities exhibited resilience over the past several months as investors
generally tended to proceed with caution. After a strong finish to 2004, the
S&P 500 Index remained largely range-bound in 2005, with the last three months
representing the best quarter of the year. Up to this point, strong corporate
earnings reports and low long-term bond yields have worked in favor of
equities. Looking ahead, high energy prices, continued interest rate hikes, a
potential consumer slowdown and/or disappointing earnings pose the greatest
risks to U.S. stocks. Internationally, many markets have benefited from strong
economic statistics, trade surpluses and solid finances.

In the bond market, the yield curve continued to flatten as short-term
interest rates moved in concert with the Fed rate hikes and longer-term
interest rates remained more constant or declined. The difference between two-
year and 10-year Treasury yields collapsed from 151 basis points (1.51%) on
September 30, 2004 to 70 basis points on March 31, 2005, to just 16 basis
points at period-end.

Financial markets are likely to face continued crosscurrents in the months
ahead. Nevertheless, opportunities do exist and we encourage you to work with
your financial advisor to diversify your portfolio among a variety of asset
types. This can help to diffuse risk while also tapping into the potential
benefits of a broader range of investment alternatives. As always, we thank
you for trusting Merrill Lynch Investment Managers with your investment
assets, and we look forward to serving you in the months and years ahead.



Sincerely,



(Robert C. Doll, Jr.)
Robert C. Doll, Jr.
President and Director



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



A Discussion With Your Fund's Portfolio Manager


The Fund provided a competitive return and above-average yield as we continued
to shift our emphasis further out on the yield curve, favoring bonds with
maturities longer than 20 years.


Describe the recent market environment relative to municipal bonds.

Over the past year, long-term bond yields generally declined as their prices,
which move in the opposite direction, increased. The rise in bond prices came
in response to several favorable factors, including moderating U.S. economic
growth, slowing foreign economies, modest inflation, and strong demand from
Asian governments for U.S. Treasury securities. Late in the period, the
devastation of Hurricane Katrina throughout the U.S. Gulf Coast prompted a
particularly strong rally in the bond market. The resultant higher energy
prices and expected declines in consumer confidence and spending pushed
longer-term interest rates downward.

The Federal Reserve Board (the Fed) continued to raise short-term interest
rates at each of its meetings during the period, lifting the federal funds
target to 3.75% by period-end. As short-term interest rates moved higher in
concert with Fed interest rate hikes and longer-term bond yields held steadier
or declined, the yield curve continued to flatten. During the past 12 months,
30-year U.S. Treasury bond yields declined 68 basis points (.68%) to 4.57%
while 10-year Treasury note yields rose 20 basis points to 4.34%. Tax-exempt
bond yields exhibited a similar pattern during the year. According to
Municipal Market Data, the yield on AAA-rated issues maturing in 30 years
declined by 48 basis points to 4.22% while the yield on AAA-rated bonds
maturing in 10 years rose by 26 basis points to 3.73%.

Historically low tax-exempt bond yields have continued to encourage
municipalities to issue new debt and refund outstanding, higher-couponed
issues. During the past year, more than $402 billion in new long-term tax-
exempt bonds was issued, an 11.2% increase over the previous year's total of
$361 billion. During the first nine months of 2005, the volume of refunding
issues increased by more than 55% on a year-over-year basis. The refunding
issues have been heavily weighted in the 10-year--20-year maturity range,
putting pressure on intermediate tax-exempt bond yields while supporting
longer-term bond prices.

Investor demand for municipal bonds remained generally positive. The most
current statistics from the Investment Company Institute indicate that,
year-to-date through August 31, 2005, net new cash flows into long-term
municipal bond funds exceeded $5.7 billion - a significant improvement from
the $12.4 billion net outflow seen during the same period in 2004. Weekly
figures for September, as reported by AMG Data Service, pointed to continued
positive cash flows.

Notably, throughout much of the past year, high yield tax-exempt bond funds
have been the principal target for the new cash inflows. During September,
these lower-rated/non-rated bond funds received an average of $150 million per
week. The need to invest these cash flows has led to strong demand for lower-
rated issues and a consequent narrowing of credit spreads.

Solid investor demand for tax-exempt issues generally helped municipal bond
performance approach that of taxable bonds in recent months and reverse their
prior underperformance. The ratio of tax-exempt bond yields to taxable bond
yields remains above recent historic averages. We believe the attractive
relative yields should continue to attract both traditional and nontraditional
investors to the municipal marketplace, especially if municipal bond issuance
remains manageable.

The communities shattered by Hurricane Katrina and Hurricane Rita will require
extensive reconstruction. It is too early to estimate the amount of tax-exempt
debt that may be required to finance these efforts or to assess the overall
impact on the municipal market. However, much of the rebuilding is likely to
be funded through federal loans and grants, and the reconstruction will likely
be spread over a number of years. Consequently, any new municipal bond
issuance prompted by Katrina is not likely to disrupt the tax-exempt market in
the near future.


How did the Fund perform during the fiscal year?

For the 12-month period ended September 30, 2005, the Common Stock of
MuniHoldings Insured Fund II, Inc. had net annualized yields of 6.16% and
6.30%, based on a year-end per share net asset value of $14.23 and a per share
market price of $13.90, respectively, and $.876 per share income dividends.
Over the same period, the total investment return on the Fund's Common Stock
was +5.35%, based on a change in per share net asset value from $14.41 to
$14.23, and assuming reinvestment of all distributions.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



The Fund's total return, based on net asset value, outpaced the +5.24% average
return of the Lipper Insured Municipal Debt Funds (Leveraged) category for the
12-month period. (Funds in this Lipper category invest primarily in municipal
debt issues insured as to timely payment. These funds can be leveraged via use
of debt, preferred equity and/or reverse repurchase agreements.) Fund
performance was primarily influenced by our yield curve strategy. For most of
the period, we were overweight bonds with maturities greater than 20 years.
This benefited performance as the yield curve flattened and longer-term bonds
outperformed shorter-term issues. However, we limited our exposure to bonds
with maturities of 30 years and longer because of their heightened interest
rate risk. This detracted somewhat from relative performance as bonds maturing
past 30 years were the municipal market's best performers.

In an effort to preserve the Fund's competitive yield, we maintained our
holdings in five-year - 10-year prerefunded bonds, which offered higher
accrual rates than currently available in the low-yield environment. This
benefited the Fund's yield, but hampered its total return somewhat as rates on
bonds with maturities of 15 years and shorter rose (and their prices
correspondingly fell).

For the six-month period ended September 30, 2005, the total investment return
on the Fund's Common Stock was +3.38%, based on a change in per share net
asset value from $14.21 to $14.23, and assuming reinvestment of all
distributions.

For a description of the Fund's total investment return based on a change in
the per share market value of the Fund's Common Stock (as measured by the
trading price of the Fund's shares on the New York Stock Exchange), and
assuming reinvestment of dividends, please refer to the Financial Highlights
section of this report. As a closed-end fund, the Fund's shares may trade in
the secondary market at a premium or discount to the Fund's net asset value.
As a result, total investment returns based on changes in the market value of
the Fund's Common Stock may vary significantly from total investment returns
based on changes in the Fund's net asset value.


What changes were made to the portfolio during the period?

We continued to focus on securities that we felt represented the best relative
value in the insured municipal marketplace. With the yield curve flattening,
we continued to shift our emphasis further out on the curve, favoring bonds
with maturity dates of 20 years and longer while reducing our exposure to 15-
year and 20-year bonds. New purchases were concentrated on issuers that we
believed were more likely to defease their existing debt to help close budget
gaps. When bonds are defeased, it typically means that the securities are
retired at their first call date, enabling the bonds to appreciate
significantly. Massachusetts, California and New Jersey are three such state
issuers that have been aggressive in this strategy.

For the six months ended September 30, 2005, the Fund's Auction Market
Preferred Stock (AMPS) had average yields of 2.32% for Series A, 2.28% for
Series B and 2.34% for Series C. Continued short-term interest rate increases
by the Fed have continued to boost the Fund's borrowing costs. The Fed raised
the short-term interest rate target 200 basis points during the 12-month
period. Although we believe the majority of the Fed's actions have already
occurred, additional rate hikes are expected until at least year-end.
Nevertheless, the Fund's borrowing costs have remained historically very low,
and the leveraging of Preferred Stock has continued to generate an income
benefit to the holders of Common Stock. However, should the spread between
short-term and long-term interest rates narrow, the benefits of leverage will
decline and, as a result, reduce the yield on the Fund's Common Stock. At the
end of the period, the Fund's leverage amount, due to AMPS, was 39.02% of
total net assets, before the deduction of Preferred Stock. (For a more
complete explanation of the benefits and risks of leveraging, see page 2 of
this report to shareholders.)


How would you characterize the Fund's position at the close of the period?

At period-end, the portfolio was fully invested and neutrally positioned with
regard to interest rate risk. We continue to emphasize a competitive yield and
preservation of the portfolio's net asset value. Although we have begun to
restructure the portfolio by purchasing bonds with slightly longer maturity
dates, the securities added in recent months have tended to be premium-coupon
bonds with defensive characteristics, allowing us to extend our average
duration while still maintaining a fairly conservative approach.


Robert A. DiMella, CFA
Vice President and Portfolio Manager


October 10, 2005



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Proxy Results


During the six-month period ended September 30, 2005, MuniHoldings Insured
Fund II, Inc.'s Common Stock shareholders voted on the following proposal. The
proposal was approved at a shareholders' meeting on April 28, 2005. A
description of the proposal and number of shares voted are as follows:



                                                                        Shares Voted     Shares Withheld
                                                                            For            From Voting
                                                                                    
1. To elect the Fund's Directors:             Robert C. Doll, Jr.        14,066,426          687,597
                                              Joe Grills                 14,064,422          689,601
                                              Herbert I. London          14,062,440          691,583
                                              Roberta Cooper Ramo        14,061,516          692,507
                                              Stephen B. Swensrud        14,063,466          690,557




During the six-month period ended September 30, 2005, MuniHoldings Insured
Fund II, Inc.'s Preferred Stock shareholders (Series A - C) voted on the
following proposal. The proposal was approved at a shareholders' meeting on
April 28, 2005. A description of the proposal and number of shares voted are
as follows:



                                                                        Shares Voted     Shares Withheld
                                                                            For            From Voting
                                                                                         
1. To elect the Fund's Board of Directors:    Robert C. Doll, Jr.          5,135                4
                                              James H. Bodurtha            5,135                4
                                              Joe Grills                   5,135                4
                                              Herbert I. London            5,135                4
                                              Roberta Cooper Ramo          5,130                9
                                              Robert S. Salomon, Jr.       5,135                4
                                              Stephen B. Swensrud          5,130                9



Portfolio Information as of September 30, 2005


Quality Ratings by                      Percent of
S&P/Moody's                         Total Investments

AAA/Aaa                                    89.6%
AA/Aa                                       3.3
A/A                                         4.4
BBB/Baa                                     1.9
Other*                                      0.8

 * Includes portfolio holdings in variable rate demand notes and
   short-term investments.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Schedule of Investments                                          (In Thousands)


     Face
   Amount    Municipal Bonds                                              Value

Alabama--1.2%

  $ 3,580    Jefferson County, Alabama, Limited Obligation
                School Warrants, Series A, 5.50% due 1/01/2022       $    3,863


Alaska--1.3%

    2,000    Anchorage, Alaska, Water Revenue Refunding
                Bonds, 6% due 9/01/2024 (a)                               2,200
    1,700    Matanuska-Susitna Boro, Alaska, GO, Series A,
                6% due 3/01/2010 (d)(e)                                   1,889


Arkansas--2.1%

    6,105    Arkansas State Development Finance Authority,
                M/F Mortgage Revenue Refunding Bonds, DRIVERS,
                Series 964Z, 7.638% due 6/01/2010 (d)(f)(i)               6,700


California--36.2%

    5,355    California Pollution Control Financing Authority, PCR,
                Refunding, DRIVERS, AMT, Series 878Z, 7.617%
                due 12/01/2009 (d)(i)                                     6,183
             California State Department of Water Resources,
                Power Supply Revenue Bonds, Series A:
    6,865           5.375% due 5/01/2017 (j)                              7,493
    5,400           5.25% due 5/01/2020                                   5,816
    5,790           5.375% due 5/01/2022                                  6,302
    4,675    California State, GO, Refunding, RIB, AMT,
                Series 777X, 7.70% due 12/01/2021 (d)(i)                  4,849
    3,000    California State Public Works Board, Lease Revenue
                Bonds (Department of General Services--Capitol
                East End Complex), Series A, 5% due 12/01/2027 (a)        3,108
    2,100    California State, Various Purpose, GO, 5.50%
                due 4/01/2028                                             2,316
             Cerritos, California, Community College District, GO
                (Election of 2004), Series A (d):
      110           5% due 8/01/2025                                        115
       85           5% due 8/01/2026                                         89
    2,800    Compton, California, Unified School District, GO
                (Election of 2002), Series B, 5.50%
                due 6/01/2025 (d)                                         3,092
    2,405    Dixon, California, Unified School District, GO (Election
                of 2002), 5.20% due 8/01/2044 (c)                         2,519
             East Side Union High School District, California, Santa
                Clara County, GO (Election of 2002), Series D (j):
    2,185           5% due 8/01/2020                                      2,335
    8,460           5% due 8/01/2029                                      8,847
             Los Angeles, California, Unified School District, GO:
    3,400       (Election of 1997), Series F, 5% due 1/01/2028 (b)        3,564
   10,110       Series A, 5% due 1/01/2028 (d)                           10,597
    3,050       Series E, 5% due 7/01/2025 (a)                            3,226
    4,240    Modesto, California, Schools Infrastructure
                Financing Agency, Special Tax Bonds, 5.50%
                due 9/01/2036 (a)                                         4,653



     Face
   Amount    Municipal Bonds                                              Value

California (concluded)

  $ 5,000    Port of Oakland, California, Revenue Refunding
                Bonds, AMT, Series L, 5.375%
                due 11/01/2027 (b)                                   $    5,346
    1,500    Port of Oakland, California, Trust Receipts,
                Revenue Bonds, AMT, Class R, Series K,
                8.37% due 11/01/2021 (b)(i)                               1,726
    2,985    Roseville, California, Joint Union High School
                District, GO (Election of 2004), Series A, 5%
                due 8/01/2029 (b)                                         3,124
    2,130    Sacramento, California, City Financing Authority,
                Capital Improvement Revenue Bonds (911 Call
                Center and Other Municipal Projects), 5%
                due 12/01/2027 (a)                                        2,220
    5,075    San Francisco, California, City and County, GO
                (California Academy of Sciences Improvements),
                Series E, 5% due 6/15/2022 (d)                            5,372
    1,250    San Francisco, California, City and County Airport
                Commission, International Airport, Special
                Facilities Lease Revenue Bonds (SFO Fuel
                Company LLC), AMT, Series A, 6.10%
                due 1/01/2020 (c)                                         1,341
    3,800    San Jose, California, GO (Libraries, Parks and
                Public Safety Projects), 5% due 9/01/2030 (d)             3,961
    4,620    Tustin, California, Unified School District, Senior Lien
                Special Tax Bonds (Community Facilities District
                No. 97-1), Series A, 5% due 9/01/2038 (c)                 4,759
             University of California Revenue Bonds (Multiple
                Purpose Projects), Series Q (c):
    3,000           5% due 9/01/2022                                      3,150
    6,710           5% due 9/01/2031                                      6,984
    5,060    William S. Hart Union High School District,
                California, Capital Appreciation, GO (Election of
                2001), Series B, 4.70%** due 9/01/2023 (c)                2,167


Colorado--3.7%

             Aurora, Colorado, COP (a):
    3,055           5.75% due 12/01/2019                                  3,369
    3,230           5.75% due 12/01/2020                                  3,548
      365    Colorado HFA, Revenue Refunding Bonds
                (S/F Program), AMT, Senior Series A-2, 7.50%
                due 4/01/2031                                               389
    4,000    Colorado Health Facilities Authority, Hospital
                Revenue Refunding Bonds (Poudre Valley Health
                Care), Series A, 5.75% due 12/01/2009 (c)(e)              4,417


Connecticut--0.9%

    2,770    Connecticut State, GO, Series D, 5%
                due 12/01/2024 (d)                                        2,941



Portfolio Abbreviations


To simplify the listings of MuniHoldings Insured Fund II, Inc.'s portfolio
holdings in the Schedule of Investments, we have abbreviated the names of
many of the securities according to the list at right.


AMT      Alternative Minimum Tax (subject to)
COP      Certificates of Participation
DRIVERS  Derivative Inverse Tax-Exempt Receipts
EDA      Economic Development Authority
GO       General Obligation Bonds
HDA      Housing Development Authority
HFA      Housing Finance Agency
IDA      Industrial Development Authority
IDR      Industrial Development Revenue Bonds
M/F      Multi-Family
PCR      Pollution Control Revenue Bonds
RIB      Residual Interest Bonds
S/F      Single-Family
VRDN     Variable Rate Demand Notes



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Schedule of Investments (continued)                              (In Thousands)


     Face
   Amount    Municipal Bonds                                              Value

Florida--0.2%

  $ 3,670    Miami-Dade County, Florida, Subordinate Special
                Obligation Revenue Bonds, Series A, 5.24%**
                due 10/01/2037 (d)                                   $      707


Georgia--1.0%

    3,000    Augusta, Georgia, Water and Sewer Revenue Bonds,
                5.25% due 10/01/2034 (c)                                  3,229


Idaho--0.3%

      905    Idaho Housing and Finance Association,
                S/F Mortgage Revenue Bonds, AMT, Series E, 6%
                due 1/01/2032                                               909


Illinois--10.0%

             Chicago, Illinois, GO, Series A (b)(e):
   18,130           6% due 7/01/2010                                     20,413
    2,185           (Neighborhoods Alive 21 Program), 6%
                    due 7/01/2010                                         2,460
    3,650    Chicago, Illinois, O'Hare International Airport
                Revenue Bonds, DRIVERS, AMT, Series 845-Z,
                8.906% due 1/01/2012 (d)(i)(j)                            4,527
    4,020    Counties of Madison, Jersey, Macoupin, Calhoun,
                Morgan, Scottand Greene and State of Illinois,
                Community College District Number 536
                (Lewis & Clark), GO (Alternate Revenue Source),
                Series 2005B, 5.25% due 11/01/2030 (c)                    4,319
      125    Lake, Cook, Kane and McHenry Counties, Illinois,
                Community Unit School District No. 220, GO, 6%
                due 12/01/2020 (b)                                          139


Indiana--4.2%

    3,000    Indiana Transportation Finance Authority, Highway
                Revenue Bonds, Series A, 5.25% due 6/01/2029 (b)          3,218
    9,280    Shelbyville, Indiana, Elementary School Building
                Corporation Revenue Bonds, First Mortgage,
                5.75% due 1/15/2009 (c)(e)                               10,105


Kansas--2.1%

    3,510    Kansas State Development Finance Authority, Health
                Facilities Revenue Bonds (Sisters of Charity
                Leavenworth), Series J, 6.125% due 12/01/2020             3,856
    2,805    Sedgwick and Shawnee Counties, Kansas,
                S/F Mortgage Revenue Bonds, AMT, Series A-2,
                6.20% due 12/01/2033 (g)(k)                               2,861


Louisiana--0.7%

    2,000    Louisiana Local Government, Environmental Facilities,
                Community Development Authority Revenue Bonds
                (Capital Projects and Equipment Acquisition),
                Series A, 6.30% due 7/01/2030 (a)                         2,176


Massachusetts--12.3%

    5,865    Massachusetts Bay Transportation Authority, Sales
                Tax Revenue Refunding Bonds, Senior Series A, 5%
                due 7/01/2035                                             6,040
    5,440    Massachusetts State, HFA, Rental Housing Mortgage
                Revenue Bonds, AMT, Series A, 5.15%
                due 7/01/2026 (c)                                         5,489
   10,565    Massachusetts State School Building Authority,
                Dedicated Sales Tax Revenue Bonds, Series A, 5%
                due 8/15/2030 (c)                                        11,094
   15,000    Massachusetts State Special Obligation Dedicated
                Tax Revenue Bonds, 5.25% due 1/01/2014 (b)(e)            16,527



     Face
   Amount    Municipal Bonds                                              Value

Michigan--2.2%

  $ 1,000    Michigan State Hospital Finance Authority, Revenue
                Refunding Bonds (Mercy-Mount Clemens), Series A,
                6% due 5/15/2014 (d)                                 $    1,092
             Michigan State Strategic Fund, Limited Obligation
                Revenue Refunding Bonds, DRIVERS, AMT (i)(j):
    2,500           Series 857Z, 8.206% due 3/01/2010                     2,819
    1,000           Series 858Z, 7.908% due 12/01/2011                    1,138
    1,500    Saint Clair County, Michigan, Economic Revenue
                Refunding Bonds (Detroit Edison Company), RIB,
                Series 282, 9.74% due 8/01/2024 (a)(i)                    1,798


Minnesota--4.4%

             Prior Lake, Minnesota, Independent School District
                Number 719, GO (c):
    2,555           5.50% due 2/01/2016                                   2,759
    1,830           5.50% due 2/01/2017                                   1,973
    3,570           5.50% due 2/01/2018                                   3,849
    2,840           5.50% due 2/01/2019                                   3,062
    2,185    Sauk Rapids, Minnesota, Independent School
                District Number 47, GO, Series A, 5.625%
                due 2/01/2018 (d)                                         2,398


Nebraska--1.9%

             Omaha Convention Hotel Corporation, Nebraska,
                Convention Center Revenue Bonds, First Tier,
                Series A (a):
    1,410           5.50% due 4/01/2020                                   1,546
    3,985           5.50% due 4/01/2022                                   4,370


Nevada--3.9%

    1,750    Clark County, Nevada, IDR (Power Company Project),
                AMT, Series A, 6.70% due 6/01/2022 (b)                    1,761
      185    Nevada Housing Division, S/F Mortgage Revenue
                Bonds, AMT, Series A-2, 6.30% due 4/01/2022 (d)             187
             Truckee Meadows, Nevada, Water Authority, Water
                Revenue Bonds, Series A (c):
    5,000           5.50% due 7/01/2018                                   5,473
    4,445           5.50% due 7/01/2019                                   4,865


New Jersey--9.8%

             New Jersey EDA, Cigarette Tax Revenue Bonds:
    8,590           5.75% due 6/15/2029                                   9,133
    6,200           5.75% due 6/15/2034                                   6,852
   11,000    New Jersey EDA, Motor Vehicle Surcharge Revenue
                Bonds, Series A, 5.25% due 7/01/2033 (d)                 11,863
    3,000    New Jersey State Turnpike Authority, Turnpike
                Revenue Bonds, Series C, 5% due 1/01/2030 (c)             3,166


New Mexico--1.6%

    5,000    Farmington, New Mexico, PCR, Refunding (Public
                Service Company of San Juan), Series C, 5.70%
                due 12/01/2016 (a)                                        5,246


New York--18.1%

             Metropolitan Transportation Authority, New York,
                Revenue Bonds:
    8,010           Series A, 5% due 11/15/2019 (a)                       8,623
    1,940           Series B, 5% due 11/15/2030                           2,046
   14,000    Nassau Health Care Corporation, New York, Health
                System Revenue Bonds, 5.75% due 8/01/2009 (c)(e)         15,571



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Schedule of Investments (continued)                              (In Thousands)


     Face
   Amount    Municipal Bonds                                              Value


New York (concluded)

  $ 5,000    New York City, New York, GO, Refunding, Series G,
                5.75% due 2/01/2017 (c)                              $    5,119
    6,750    New York City, New York, Sales Tax Asset Receivable
                Corporation Revenue Bonds, Series A, 5.25%
                due 10/15/2027 (a)                                        7,305
    4,345    New York State Dormitory Authority Revenue Bonds
                (School Districts Financing Program), Series D,
                5.25% due 10/01/2023 (d)                                  4,710
      200    New York State Local Government Assistance
                Corporation, Revenue Refunding Bonds, Sub-Lien,
                VRDN, Series A-5V, 2.68% due 4/01/2020 (c)(h)               200
             Tobacco Settlement Financing Corporation of New
                York Revenue Bonds:
    2,000           Series A-1, 5.25% due 6/01/2021 (a)                   2,169
    7,850           Series C-1, 5.50% due 6/01/2017                       8,566
    3,000           Series C-1, 5.50% due 6/01/2021                       3,272


North Carolina--0.5%

    1,445    North Carolina HFA, Home Ownership Revenue
                Bonds, AMT, Series 14-A, 5.35%
                due 1/01/2022 (a)                                         1,497


Ohio--1.0%

    1,745    Aurora, Ohio, City School District, COP, 6.10%
                due 12/01/2009 (d)(e)                                     1,954
    1,000    Kent State University, Ohio, University Revenue
                Bonds, 6% due 5/01/2024 (a)                               1,110


Oklahoma--1.2%

    3,385    Claremore, Oklahoma, Public Works Authority,
                Capital Improvement Revenue Refunding Bonds,
                Series A, 5.25% due 6/01/2027 (c)                         3,670


Pennsylvania--12.7%

    4,480    Lehigh County, Pennsylvania, IDA, PCR, Refunding
                (Pennsylvania Power and Light Utilities Corporation
                Project), 4.75% due 2/15/2027 (b)                         4,548
    5,600    Lycoming County, Pennsylvania, College Authority
                Revenue Bonds (Pennsylvania College of
                Technology), 5.25% due 7/01/2007 (d)(e)                   5,864
    3,000    Pennsylvania State Higher Educational Facilities
                Authority, Revenue Bonds (Slippery Rock University
                Foundation, Inc.), Series A, 5% due 7/01/2037 (j)         3,103
    6,435    Pennsylvania State Higher Educational Facilities
                Authority, State System of Higher Education
                Revenue Bonds, Series O, 5.125%
                due 6/15/2024 (a)                                         6,610
   10,565    Philadelphia, Pennsylvania, Water and Wastewater
                Revenue Bonds, Series A, 5% due 7/01/2027 (c)            11,105
    2,800    Sayre, Pennsylvania, Health Care Facilities Authority,
                Revenue Refunding Bonds (Guthrie Healthcare
                System), Series A, 5.875% due 12/01/2031                  3,002
             Seneca Valley, Pennsylvania, School District, GO (b):
    1,390       5% due 1/01/2020                                          1,487
    2,260       5% due 1/01/2021                                          2,413
    2,090    Washington County, Pennsylvania, Capital Funding
                Authority Revenue Bonds (Capital Projects and
                Equipment Program), 6.15% due 12/01/2029 (a)              2,228



     Face
   Amount    Municipal Bonds                                              Value

Rhode Island--3.5%

  $ 5,555    Providence, Rhode Island, Redevelopment Agency
                Revenue Refunding Bonds (Public Safety and
                Municipal Buildings), Series A, 5.75%
                due 4/01/2010 (a)(e)                                 $    6,171
    4,685    Rhode Island State Health and Educational Building
                Corporation Revenue Bonds (Rhode Island School
                of Design), Series D, 5.50% due 8/15/2031 (j)             5,128


South Carolina--2.0%

    3,600    Newberry County, South Carolina, School District,
                Installment Purchase Revenue Bonds, 5%
                due 12/01/2027                                            3,725
    2,490    South Carolina Housing Finance and Development
                Authority, Mortgage Revenue Refunding Bonds,
                AMT, Series A-2, 6.35% due 7/01/2019 (c)                  2,658


Tennessee--2.0%

    3,500    Metropolitan Government of Nashville and
                Davidson County, Tennessee, Health and Education
                Facilities Board Revenue Refunding Bonds
                (Ascension Health Credit), Series A, 5.875%
                due 11/15/2009 (a)(e)                                     3,879
    1,080    Tennessee HDA, Revenue Bonds (Homeownership
                Program), AMT, Series 2C, 6% due 7/01/2011                1,102
    1,515    Tennessee HDA, Revenue Refunding Bonds
                (Homeownership Program), AMT, Series 1,
                6.05% due 7/01/2014 (d)                                   1,535


Texas--10.8%

    1,750    Austin, Texas, Convention Center Revenue Bonds
                (Convention Enterprises Inc.), Trust Certificates,
                Second Tier, Series B, 6% due 1/01/2023                   1,869
      500    Bell County, Texas, Health Facilities Development
                Corporation, Hospital Revenue Bonds (Scott & White
                Memorial Hospital), VRDN, Series B-1, 2.72%
                due 8/15/2029 (d)(h)                                        500
    8,000    Dallas-Fort Worth, Texas, International Airport Revenue
                Bonds, DRIVERS, AMT, Series 778-Z, 7.906%
                due 11/01/2011 (d)(i)                                     9,018
             Dallas-Fort Worth, Texas, International Airport Revenue
                Refunding and Improvement Bonds, AMT, Series A (b):
    1,835           5.875% due 11/01/2017                                 2,017
    2,150           5.875% due 11/01/2018                                 2,363
    2,390           5.875% due 11/01/2019                                 2,627
             El Paso, Texas, Water and Sewer Revenue Refunding
                and Improvement Bonds, Series A (c):
      115           6% due 3/01/2015                                        131
      170           6% due 3/01/2016                                        193
      180           6% due 3/01/2017                                        204
    5,150    Harris County, Texas, Toll Road Senior Lien Revenue
                and Refunding Bonds, Series 2005A, 5.25%
                due 8/15/2035 (c)                                         5,398
    4,734    Houston, Texas, Community College System,
                Participation Interests, COP (Alief Center Project),
                5.75% due 8/15/2022 (d)                                   5,063
    1,850    Midland, Texas, Certificates of Obligation, GO, 6.10%
                due 3/01/2027 (b)                                         2,039
    2,650    Waskom, Texas, Independent School District, GO
                (School Building), 5.25% due 2/15/2035 (c)                2,868



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Schedule of Investments (concluded)                              (In Thousands)


     Face
   Amount    Municipal Bonds                                              Value

Utah--0.2%

  $   610    Weber County, Utah, Municipal Building Authority,
                Lease Revenue Refunding Bonds, 5.75%
                due 12/15/2007 (d)(e)                                 $     651


Washington--6.9%

    6,885    Bellevue, Washington, GO, Refunding, 5.50%
                due 12/01/2039 (d)                                        7,531
    3,840    Chelan County, Washington, Public Utility District
                Number 001, Consolidated Revenue Bonds
                (Chelan Hydro System), AMT, Series A, 5.45%
                due 7/01/2037 (a)                                         4,068
             Lewis County, Washington, GO, Refunding (a):
    1,805           5.75% due 12/01/2009 (e)                              1,981
    1,640           5.75% due 12/01/2024                                  1,782
    2,500    Seattle, Washington, Municipal Light and Power
                Revenue Bonds, 6% due 10/01/2009 (d)(e)                   2,780
    3,500    Seattle, Washington, Water System Revenue Bonds,
                Series B, 6% due 7/01/2029 (b)                            3,832


West Virginia--2.0%

    6,210    West Virginia State Housing Development Fund,
                Housing Finance Revenue Refunding Bonds,
                Series D, 5.20% due 11/01/2021 (d)                        6,419



     Face
   Amount    Municipal Bonds                                              Value

Wisconsin--0.2%

  $   750    Wisconsin State Health and Educational Facilities
                Authority Revenue Bonds (Blood Center of
                Southeastern Wisconsin Project), 5.75%
                due 6/01/2034                                        $      795


Puerto Rico--2.1%

    6,225    Puerto Rico Commonwealth, Public Improvement,
                GO, 5.125% due 7/01/2030 (c)                              6,600

             Total Municipal Bonds
             (Cost--$497,944)--163.2%                                   519,088




   Shares
     Held    Short-Term Securities

    3,589    Merrill Lynch Institutional Tax-Exempt Fund (l)              3,589

             Total Short-Term Securities
             (Cost--$3,589)--1.1%                                         3,589

Total Investments (Cost--$501,533*)--164.3%                             522,677
Liabilities in Excess of Other Assets--(0.0%)                             (133)
Preferred Stock, at Redemption Value--(64.3%)                         (204,500)
                                                                     ----------
Net Assets Applicable to Common Stock--100.0%                        $  318,044
                                                                     ==========


  * The cost and unrealized appreciation (depreciation) of investments as of
    September 30, 2005, as computed for federal income tax purposes, were as
    follows:


    Aggregate cost                                  $       501,639
                                                    ===============
    Gross unrealized appreciation                   $        22,252
    Gross unrealized depreciation                           (1,214)
                                                    ---------------
    Net unrealized appreciation                     $        21,038
                                                    ===============


 ** Represents a zero coupon bond; the interest rate shown reflects the
    effective yield at the time of purchase.

(a) AMBAC Insured.

(b) FGIC Insured.

(c) FSA Insured.

(d) MBIA Insured.

(e) Prerefunded.

(f) FHA Insured.

(g) FNMA Collateralized.

(h) Security may have a maturity of more than one year at time of issuance, but
    has variable rate and demand features that qualify it as a short-term
    security. The rate disclosed is that currently in effect. This rate changes
    periodically based upon prevailing market rates.

(i) The rate disclosed is that currently in effect. This rate changes
    periodically and inversely based upon prevailing market rates.

(j) XL Capital Insured.

(k) GNMA Collateralized.

(l) Investments in companies considered to be an affiliate of the Fund, for
    purposes of Section 2(a)(3) of the Investment Company Act of 1940, were as
    follows:

                                                        Net        Dividend
    Affiliate                                         Activity      Income

    Merrill Lynch Institutional Tax-Exempt Fund       (12,600)       $81


    Financial futures contracts sold as of September 30, 2005 were as follows:


    Number of                     Expiration        Face        Unrealized
    Contracts      Issue             Date          Value       Appreciation

      250       10-Year U.S.       December
               Treasury Bond         2005         $27,642          $161


    See Notes to Financial Statements.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Statement of Net Assets


As of September 30, 2005
                                                                                                         
Assets

           Investments in unaffiliated securities, at value (identified cost--$497,943,652)                       $   519,087,212
           Investments in affiliated securities, at value (identified cost--$3,589,380)                                 3,589,380
           Cash                                                                                                            28,930
           Receivables:
               Securities sold                                                                 $    10,359,683
               Interest                                                                              7,698,893
               Variation margin                                                                         82,031
               Dividends from affiliates                                                                   254         18,140,861
                                                                                               ---------------
           Prepaid expenses                                                                                                 8,296
                                                                                                                  ---------------
           Total assets                                                                                               540,854,679
                                                                                                                  ---------------

Liabilities

           Payables:
               Securities purchased                                                                 17,868,382
               Investment adviser                                                                      199,774
               Dividends to Common Stock shareholders                                                  151,801
               Other affiliates                                                                          5,598         18,225,555
                                                                                               ---------------
           Accrued expenses                                                                                                84,704
                                                                                                                  ---------------
           Total liabilities                                                                                           18,310,259
                                                                                                                  ---------------

Preferred Stock

           Preferred Stock, at redemption value, par value $.10 per share (2,100 Series A
           Shares, 2,100 Series B Shares and 3,980 Series C Shares of AMPS* authorized,
           issued and outstanding at $25,000 per share liquidation preference)                                        204,500,000
                                                                                                                  ---------------

Net Assets Applicable to Common Stock

           Net assets applicable to Common Stock                                                                  $   318,044,420
                                                                                                                  ===============

Analysis of Net Assets Applicable to Common Stock

           Common Stock, par value $.10 per share (22,352,426 shares issued and outstanding)                      $     2,235,243
           Paid-in capital in excess of par                                                                           313,735,958
           Undistributed investment income--net                                                $     3,616,928
           Accumulated realized capital losses--net                                               (22,848,681)
           Unrealized appreciation--net                                                             21,304,972
                                                                                               ---------------
           Total accumulated earnings--net                                                                              2,073,219
                                                                                                                  ---------------
           Total--Equivalent to $14.23 net asset value per share of Common Stock
           (market price--$13.90)                                                                                 $   318,044,420
                                                                                                                  ===============

               * Auction Market Preferred Stock.

                 See Notes to Financial Statements.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Statement of Operations


For the Year Ended September 30, 2005
                                                                                                         
Investment Income

           Interest                                                                                               $    25,394,274
           Dividends from affiliates                                                                                       81,447
                                                                                                                  ---------------
           Total income                                                                                                25,475,721
                                                                                                                  ---------------

Expenses

           Investment advisory fees                                                            $     2,910,655
           Commission fees                                                                             521,417
           Accounting services                                                                         176,538
           Transfer agent fees                                                                          61,756
           Professional fees                                                                            59,606
           Printing and shareholder reports                                                             44,989
           Custodian fees                                                                               31,540
           Directors' fees and expenses                                                                 24,350
           Pricing fees                                                                                 21,682
           Listing fees                                                                                 19,117
           Other                                                                                        54,657
                                                                                               ---------------
           Total expenses before waiver and reimbursement                                            3,926,307
           Waiver and reimbursement of expenses                                                      (199,702)
                                                                                               ---------------
           Total expenses after waiver and reimbursement                                                                3,726,605
                                                                                                                  ---------------
           Investment income--net                                                                                      21,749,116
                                                                                                                  ---------------

Realized & Unrealized Gain (Loss)--Net

           Realized gain (loss) on:
               Investments--net                                                                     11,512,359
               Futures contracts and forward interest rate swaps--net                              (3,221,912)          8,290,447
                                                                                               ---------------
           Change in unrealized appreciation/depreciation on:
               Investments--net                                                                   (12,732,580)
               Futures contracts and forward interest rate swaps--net                                2,347,537       (10,385,043)
                                                                                               ---------------    ---------------
           Total realized and unrealized loss--net                                                                    (2,094,596)
                                                                                                                  ---------------

Dividends to Preferred Stock Shareholders

           Investment income--net                                                                                     (4,101,460)
                                                                                                                  ---------------
           Net Increase in Net Assets Resulting from Operations                                                   $    15,553,060
                                                                                                                  ===============

           See Notes to Financial Statements.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Statements of Changes in Net Assets

                                                                                                       For the Year Ended
                                                                                                         September 30,
Increase (Decrease) in Net Assets:                                                                   2005                2004
                                                                                                         
Operations

           Investment income--net                                                              $    21,749,116    $    22,252,027
           Realized gain (loss)--net                                                                 8,290,447           (53,052)
           Change in unrealized appreciation/depreciation--net                                    (10,385,043)             84,198
           Dividends to Preferred Stock shareholders                                               (4,101,460)        (2,034,890)
                                                                                               ---------------    ---------------
           Net increase in net assets resulting from operations                                     15,553,060         20,248,283
                                                                                               ---------------    ---------------

Dividends to Common Stock Shareholders

           Investment income--net                                                                 (19,580,725)       (19,446,611)
                                                                                               ---------------    ---------------
           Net decrease in net assets resulting from dividends to Common Stock shareholders       (19,580,725)       (19,446,611)
                                                                                               ---------------    ---------------

Net Assets Applicable to Common Stock

           Total increase (decrease) in net assets applicable to Common Stock                      (4,027,665)            801,672
           Beginning of year                                                                       322,072,085        321,270,413
                                                                                               ---------------    ---------------
           End of year*                                                                        $   318,044,420    $   322,072,085
                                                                                               ===============    ===============
               * Undistributed investment income--net                                          $     3,616,928    $     5,549,997
                                                                                               ===============    ===============
                 See Notes to Financial Statements.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Financial Highlights


The following per share data and ratios have been derived                         For the Year Ended September 30,
from information provided in the financial statements.                2005         2004         2003         2002         2001
                                                                                                     
Per Share Operating Performance

           Net asset value, beginning of year                     $    14.41    $    14.37   $    14.48   $    13.94   $    12.72
                                                                  ----------    ----------   ----------   ----------   ----------
           Investment income--net                                      .97++        1.00++       1.02++         1.03         1.06
           Realized and unrealized gain (loss)--net                    (.09)        --++++        (.17)          .47         1.21
           Dividends and distributions to Preferred Stock
           shareholders:
               Investment income--net                                  (.18)         (.09)        (.10)        (.13)        (.31)
               Realized gain--net                                         --            --           --        --+++           --
                                                                  ----------    ----------   ----------   ----------   ----------
           Total from investment operations                              .70           .91          .75         1.37         1.96
                                                                  ----------    ----------   ----------   ----------   ----------
           Less dividends and distributions to Common Stock
           shareholders:
               Investment income--net                                  (.88)         (.87)        (.86)        (.83)        (.74)
               Realized gain--net                                         --            --           --        --+++           --
                                                                  ----------    ----------   ----------   ----------   ----------
           Total dividends and distributions to Common Stock
           shareholders                                                (.88)         (.87)        (.86)        (.83)        (.74)
                                                                  ----------    ----------   ----------   ----------   ----------
           Net asset value, end of year                           $    14.23    $    14.41   $    14.37   $    14.48   $    13.94
                                                                  ==========    ==========   ==========   ==========   ==========
           Market price per share, end of year                    $    13.90    $    13.25   $    13.13   $    13.55   $    13.04
                                                                  ==========    ==========   ==========   ==========   ==========

Total Investment Return*

           Based on net asset value per share                          5.35%         7.12%        5.95%       10.67%       16.43%
                                                                  ==========    ==========   ==========   ==========   ==========
           Based on market price per share                            11.92%         7.80%        3.45%       10.71%       28.87%
                                                                  ==========    ==========   ==========   ==========   ==========

Ratios Based on Average Net Assets of Common Stock

           Total expenses, net of waiver and reimbursement**           1.15%         1.12%        1.14%        1.18%        1.09%
                                                                  ==========    ==========   ==========   ==========   ==========
           Total expenses**                                            1.21%         1.21%        1.23%        1.27%        1.26%
                                                                  ==========    ==========   ==========   ==========   ==========
           Total investment income--net**                              6.72%         6.93%        7.19%        7.44%        7.83%
                                                                  ==========    ==========   ==========   ==========   ==========
           Amount of dividends to Preferred Stock shareholders         1.27%          .63%         .69%         .97%        2.28%
                                                                  ==========    ==========   ==========   ==========   ==========
           Investment income--net, to Common Stock
           shareholders                                                5.45%         6.30%        6.50%        6.47%        5.55%
                                                                  ==========    ==========   ==========   ==========   ==========

Ratios Based on Average Net Assets of Preferred Stock

           Dividends to Preferred Stock shareholders                   1.99%          .99%        1.08%        1.46%        3.36%
                                                                  ==========    ==========   ==========   ==========   ==========



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Financial Highlights (concluded)


The following per share data and ratios have been derived                         For the Year Ended September 30,
from information provided in the financial statements.                2005         2004         2003         2002         2001
                                                                                                     
Supplemental Data

           Net assets applicable to Common Stock, end of
           year (in thousands)                                    $  318,044    $  322,072   $  321,270   $  323,678   $  311,505
                                                                  ==========    ==========   ==========   ==========   ==========
           Preferred Stock outstanding, end of year
           (in thousands)                                         $  204,500    $  204,500   $  204,500   $  204,500   $  204,500
                                                                  ==========    ==========   ==========   ==========   ==========
           Portfolio turnover                                         58.19%        45.89%       52.00%       50.73%       61.09%
                                                                  ==========    ==========   ==========   ==========   ==========

Leverage

           Asset coverage per $1,000                              $    2,555    $    2,575   $    2,571   $    2,583   $    2,523
                                                                  ==========    ==========   ==========   ==========   ==========

Dividends Per Share on Preferred Stock Outstanding

           Series A--Investment income--net                       $      505    $      253   $      268   $      362   $      820
                                                                  ==========    ==========   ==========   ==========   ==========
           Series B--Investment income--net                       $      494    $      241   $      267   $      338   $      830
                                                                  ==========    ==========   ==========   ==========   ==========
           Series C--Investment income--net                       $      504    $      251   $      271   $      381   $      850
                                                                  ==========    ==========   ==========   ==========   ==========

             * Total investment returns based on market value, which can be significantly greater or lesser
               than the net asset value, may result in substantially different returns. Total investment returns
               exclude the effects of sales charges.

            ** Do not reflect the effect of dividends to Preferred Stock shareholders.

            ++ Based on average shares outstanding.

          ++++ Amount is less than $.01 per share.

           +++ Amount is less than $(.01) per share.

               See Notes to Financial Statements.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Notes to Financial Statements


1. Significant Accounting Policies:
MuniHoldings Insured Fund II, Inc. (the "Fund") is registered under the
Investment Company Act of 1940, as amended, as a non-diversified, closed-end
management investment company. The Fund's financial statements are prepared in
conformity with U.S. generally accepted accounting principles, which may
require the use of management accruals and estimates. Actual results may
differ from these estimates. The Fund determines and makes available for
publication the net asset value of its Common Stock on a daily basis. The
Fund's Common Stock shares are listed on the New York Stock Exchange under the
symbol MUE. The following is a summary of significant accounting policies
followed by the Fund.

(a) Valuation of investments--Municipal bonds are traded primarily in the over-
the-counter ("OTC") markets and are valued at the last available bid price in
the OTC market or on the basis of values as obtained by a pricing service.
Pricing services use valuation matrixes that incorporate both dealer-supplied
valuations and valuation models. The procedures of the pricing service and its
valuations are reviewed by the officers of the Fund under the general
direction of the Board of Directors. Such valuations and procedures are
reviewed periodically by the Board of Directors of the Fund. Financial futures
contracts and options thereon, which are traded on exchanges, are valued at
their closing prices as of the close of such exchanges. Options written or
purchased are valued at the last sale price in the case of exchange-traded
options. In the case of options traded in the OTC market, valuation is the
last asked price (options written) or the last bid price (options purchased).
Swap agreements are valued by quoted fair values received daily by the Fund's
pricing service. Short-term investments with a remaining maturity of 60 days
or less are valued at amortized cost, which approximates market value, under
which method the investment is valued at cost and any premium or discount is
amortized on a straight line basis to maturity. Investments in open-end
investment companies are valued at their net asset value each business day.
Securities and other assets for which market quotations are not readily
available are valued at fair value as determined in good faith by or under the
direction of the Board of Directors of the Fund.

(b) Derivative financial instruments--The Fund may engage in various portfolio
investment strategies both to increase the return of the Fund and to hedge, or
protect, its exposure to interest rate movements and movements in the
securities markets. Losses may arise due to changes in the value of the
contract or if the counterparty does not perform under the contract.

* Financial futures contracts--The Fund may purchase or sell financial futures
contracts and options on such futures contracts. Futures contracts are
contracts for delayed delivery of securities at a specific future date and at
a specific price or yield. Upon entering into a contract, the Fund deposits
and maintains as collateral such initial margin as required by the exchange on
which the transaction is effected. Pursuant to the contract, the Fund agrees
to receive from or pay to the broker an amount of cash equal to the daily
fluctuation in value of the contract. Such receipts or payments are known as
variation margin and are recorded by the Fund as unrealized gains or losses.
When the contract is closed, the Fund records a realized gain or loss equal to
the difference between the value of the contract at the time it was opened and
the value at the time it was closed.

* Options--The Fund may purchase and write call and put options. When the Fund
writes an option, an amount equal to the premium received by the Fund is
reflected as an asset and an equivalent liability. The amount of the liability
is subsequently marked-to-market to reflect the current market value of the
option written. When a security is purchased or sold through the exercise of
an option, the related premium paid (or received) is added to (or deducted
from) the basis of the security acquired or deducted from (or added to) the
proceeds of the security sold. When an option expires (or the Fund enters into
a closing transaction), the Fund realizes a gain or loss on the option to the
extent of the premiums received or paid (or gain or loss to the extent the
cost of the closing transaction exceeds the premium paid or received).

Written and purchased options are non-income producing investments.

* Forward interest rate swaps--The Fund may enter into forward interest rate
swaps. In a forward interest rate swap, the Fund and the counterparty agree to
make periodic net payments on a specified notional contract amount, commencing
on a specified future effective date, unless terminated earlier. When the
agreement is closed, the fund records a realized gain or loss in an amount
equal to the value of the agreement.

(c) Income taxes--It is the Fund's policy to comply with the requirements of
the Internal Revenue Code applicable to regulated investment companies and to
distribute substantially all of its taxable income to its shareholders.
Therefore, no federal income tax provision is required.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Notes to Financial Statements (concluded)


(d) Security transactions and investment income--Security transactions are
recorded on the dates the transactions are entered into (the trade dates).
Realized gains and losses on security transactions are determined on the
identified cost basis. Dividend income is recorded on the ex-dividend dates.
Interest income is recognized on the accrual basis. The Fund amortizes all
premiums and discounts on debt securities.

(e) Dividends and distributions--Dividends from net investment income are
declared and paid monthly. Distributions of capital gains are recorded on the
ex-dividend dates.


2. Investment Advisory Agreement and Transactions with Affiliates:
The Fund has entered into an Investment Advisory Agreement with Fund Asset
Management, L.P. ("FAM"). The general partner of FAM is Princeton Services,
Inc. ("PSI"), an indirect, wholly-owned subsidiary of Merrill Lynch & Co.,
Inc. ("ML & Co."), which is the limited partner.

FAM is responsible for the management of the Fund's portfolio and provides the
necessary personnel, facilities, equipment and certain other services
necessary to the operations of the Fund. For such services, the Fund pays a
monthly fee at an annual rate of .55% of the Fund's average weekly net assets,
including proceeds from the issuance of Preferred Stock. FAM has agreed to
waive its management fee on the proceeds of Preferred Stock that exceeds 35%
of the Fund's total net assets. For the year ended September 30, 2005, FAM
earned fees of $2,910,655, of which $190,370 was waived. In addition, FAM has
agreed to reimburse its advisory fee by the amount of advisory fees the Fund
pays to FAM indirectly through its investment in Merrill Lynch Institutional
Tax-Exempt Fund. For the year ended September 30, 2005, FAM reimbursed the
Fund in the amount of $9,332.

For the year ended September 30, 2005, the Fund reimbursed FAM $12,478 for
certain accounting services.

Certain officers and/or directors of the Fund are officers and/or directors of
FAM, PSI, and/or ML & Co.


3. Investments:
Purchases and sales of investments, excluding short-term securities, for the
year ended September 30, 2005 were $314,029,045 and $298,838,158,
respectively.


4. Stock Transactions:
The Fund is authorized to issue 200,000,000 shares of stock, including
Preferred Stock, par value $.10 per share, all of which were initially
classified as Common Stock. The Board of Directors is authorized, however, to
reclassify any unissued shares of stock without approval of holders of Common
Stock.

Preferred Stock
Auction Market Preferred Stock are shares of Preferred Stock of the Fund, with
a par value of $.10 per share and a liquidation preference of $25,000 per
share, plus accrued and unpaid dividends, that entitle their holders to
receive cash dividends at an annual rate that may vary for the successive
dividend periods. The yields in effect at September 30, 2005 were as follows:
Series A, 2.70%; Series B, 2.78%; and Series C, 2.76%.

The Fund pays commissions to certain broker-dealers at the end of each auction
at an annual rate ranging from .25% to .375%, calculated on the proceeds of
each auction. For the year ended September, 30, 2005, Merrill Lynch, Pierce,
Fenner & Smith Incorporated, an affiliate of FAM, earned $271,023 as
commissions.


5. Distributions to Shareholders:
The Fund paid a tax-exempt income dividend to holders of Common Stock in the
amount of .073000 per share on October 28, 2005 to shareholders of record on
October 17, 2005.

The tax character of distributions paid during the fiscal years ended
September 30, 2005 and September 30, 2004 was as follows:


                                           9/30/2005          9/30/2004

Distributions paid from:
   Tax-exempt income                 $    23,682,185    $    21,481,501
                                     ---------------    ---------------
Total distributions                  $    23,682,185    $    21,481,501
                                     ===============    ===============


As of September 30, 2005, the components of accumulated earnings on a tax
basis were as follows:


Undistributed tax-exempt income--net                    $     3,616,928
Undistributed long-term capital gains--net                           --
                                                        ---------------
Total undistributed earnings--net                             3,616,928
Capital loss carryforward                                 (18,683,686)*
Unrealized gains--net                                      17,139,977**
                                                        ---------------
Total accumulated earnings--net                         $     2,073,219
                                                        ===============

*  On September 30, 2005, the Fund had a net capital loss carryforward
   of $18,683,686, of which $6,857,897 expires in 2007, $11,519,686
   expires in 2008 and $306,103 expires in 2012. This amount will be
   available to offset like amounts of any future taxable gains.

** The difference between book-basis and tax-basis net unrealized
   gains is attributable primarily to the tax deferral of losses on wash
   sales, the tax deferral of losses on straddles and the realization for tax
   purposes of unrealized gains (losses) on certain futures contracts.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Report of Independent Registered Public Accounting Firm


To the Shareholders and Board of Directors of
MuniHoldings Insured Fund II, Inc.:

We have audited the accompanying statement of net assets of MuniHoldings
Insured Fund II, Inc., including the schedule of investments, as of September
30, 2005, and the related statement of operations for the year then ended, the
statements of changes in net assets for each of the two years in the period
then ended and financial highlights for each of the periods indicated therein.
These financial statements and financial highlights are the responsibility of
the Fund's management. Our responsibility is to express an opinion on these
financial statements and financial highlights based on our audits.

We conducted our audits in accordance with the standards of the Public Company
Accounting Oversight Board (United States). Those standards require that we
plan and perform the audit to obtain reasonable assurance about whether the
financial statements and financial highlights are free of material
misstatement. We were not engaged to perform an audit of the Fund's internal
control over financial reporting. Our audits included consideration of
internal control over financial reporting as a basis for designing audit
procedures that are appropriate in the circumstances, but not for the purpose
of expressing an opinion on the effectiveness of the Fund's internal control
over financial reporting. Accordingly, we express no such opinion. An audit
also includes examining, on a test basis, evidence supporting the amounts and
disclosures in the financial statements and financial highlights, assessing
the accounting principles used and significant estimates made by management,
and evaluating the overall financial statement presentation. Our procedures
included confirmation of securities owned as of September 30, 2005, by
correspondence with the custodian and others. We believe that our audits
provide a reasonable basis for our opinion.

In our opinion, the financial statements and financial highlights referred to
above present fairly, in all material respects, the financial position of
MuniHoldings Insured Fund II, Inc. at September 30, 2005, the results of its
operations for the year then ended, the changes in its net assets for each of
the two years in the period then ended and the financial highlights for each
of the periods indicated therein in conformity with U.S. generally accepted
accounting principles.


(Ernst & Young LLP)
Philadelphia, Pennsylvania
November 9, 2005



Fund Certification (unaudited)


In May 2005, the Fund filed its Chief Executive Officer Certification for the
prior year with the New York Stock Exchange pursuant to Section 303A.12(a) of
the New York Stock Exchange Corporate Governance Listing Standards.

The Funds' Chief Executive Officer and Chief Financial Officer Certifications
pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 were filed with the
Funds' Form N-CSR and are available on the Securities and Exchange
Commission's Web site at http://www.sec.gov.



Important Tax Information (unaudited)


All of the net investment income distributions paid by MuniHoldings Insured
Fund II, Inc. during the taxable year ended September 30, 2005 qualify as tax-
exempt interest dividends for federal income tax purposes.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Automatic Dividend Reinvestment Plan


The following description of the Fund's Automatic Dividend Reinvestment Plan
(the "Plan") is sent to you annually as required by federal securities laws.

Pursuant to the Fund's Plan, unless a holder of Common Stock otherwise elects,
all dividend and capital gains distributions will be automatically reinvested
by EquiServe (the "Plan Agent"), as agent for shareholders in administering
the Plan, in additional shares of Common Stock of the Fund. Holders of Common
Stock who elect not to participate in the Plan will receive all distributions
in cash paid by check mailed directly to the shareholder of record (or, if the
shares are held in street or other nominee name then to such nominee) by
EquiServe, as dividend paying agent. Such participants may elect not to
participate in the Plan and to receive all distributions of dividends and
capital gains in cash by sending written instructions to EquiServe, as
dividend paying agent, at the address set forth below. Participation in the
Plan is completely voluntary and may be terminated or resumed at any time
without penalty by written notice if received by the Plan Agent not less than
ten days prior to any dividend record date; otherwise such termination will be
effective with respect to any subsequently declared dividend or distribution.

Whenever the Fund declares an income dividend or capital gains distribution
(collectively referred to as "dividends") payable either in shares or in cash,
non-participants in the Plan will receive cash and participants in the Plan
will receive the equivalent in shares of Common Stock. The shares will be
acquired by the Plan Agent for the participant's account, depending upon the
circumstances described below, either (i) through receipt of additional
unissued but authorized shares of Common Stock from the Fund ("newly issued
shares") or (ii) by purchase of outstanding shares of Common Stock on the open
market ("open-market purchases") on the New York Stock Exchange or elsewhere.
If, on the payment date for the dividend, the net asset value per share of the
Common Stock is equal to or less than the market price per share of the Common
Stock plus estimated brokerage commissions (such conditions being referred to
herein as "market premium"), the Plan Agent will invest the dividend amount in
newly issued shares on behalf of the participant. The number of newly issued
shares of Common Stock to be credited to the participant's account will be
determined by dividing the dollar amount of the dividend by the net asset
value per share on the date the shares are issued, provided that the maximum
discount from the then current market price per share on the date of issuance
may not exceed 5%. If, on the dividend payment date, the net asset value per
share is greater than the market value (such condition being referred to
herein as "market discount"), the Plan Agent will invest the dividend amount
in shares acquired on behalf of the participant in open-market purchases.

In the event of a market discount on the dividend payment date, the Plan Agent
will have until the last business day before the next date on which the shares
trade on an "ex-dividend" basis or in no event more than 30 days after the
dividend payment date (the "last purchase date") to invest the dividend amount
in shares acquired in open-market purchases. It is contemplated that the Fund
will pay monthly income dividends. Therefore, the period during which open-
market purchases can be made will exist only from the payment date on the
dividend through the date before the next "ex-dividend" date, which typically
will be approximately ten days. If, before the Plan Agent has completed its
open-market purchases, the market price of a share of Common Stock exceeds the
net asset value per share, the average per share purchase price paid by the
Plan Agent may exceed the net asset value of the Fund's shares, resulting in
the acquisitions of fewer shares than if the dividend had been paid in newly
issued shares on the dividend payment date. Because of the foregoing
difficulty with respect to open-market purchases, the Plan provides that if
the Plan Agent is unable to invest the full dividend amount in open-market
purchases during the purchase period or if the market discount shifts to a
market premium during the purchase period, the Plan Agent will cease making
open-market purchases and will invest the uninvested portion of the dividend
amount in newly issued shares at the close of business on the last purchase
date determined by dividing the uninvested portion of the dividend by the net
asset value per share.

The Plan Agent maintains all shareholders' accounts in the Plan and furnishes
written confirmation of all transactions in the account, including information
needed by shareholders for tax records. Shares in the account of each Plan
participant will be held by the Plan Agent in non-certificated form in the
name of the participant, and each shareholder's proxy will include those
shares purchased or received pursuant to the Plan. The Plan Agent will forward
all proxy solicitation materials to participants and vote proxies for shares
held pursuant to the Plan in accordance with the instructions of the
participants.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Automatic Dividend Reinvestment Plan (concluded)


In the case of shareholders such as banks, brokers or nominees which hold
shares of others who are the beneficial owners, the Plan Agent will administer
the Plan on the basis of the number of shares certified from time to time by
the record shareholders as representing the total amount registered in the
record shareholder's name and held for the account of beneficial owners who
are to participate in the Plan.

There will be no brokerage charges with respect to shares issued directly by
the Fund as a result of dividends or capital gains distributions payable
either in shares or in cash. However, each participant will pay a pro rata
share of brokerage commissions incurred with respect to the Plan Agent's open-
market purchases in connection with the reinvestment of dividends.

The automatic reinvestment of dividends and distributions will not relieve
participants of any federal, state or local income tax that may be payable (or
required to be withheld) on such dividends.

Shareholders participating in the Plan may receive benefits not available to
shareholders not participating in the Plan. If the market price plus
commissions of the Fund's shares is above the net asset value, participants in
the Plan will receive shares of the Fund at less than they could otherwise
purchase them and will have shares with a cash value greater than the value of
any cash distribution they would have received on their shares. If the market
price plus commissions is below the net asset value, participants will receive
distributions in shares with a net asset value greater than the value of any
cash distribution they would have received on their shares. However, there may
be insufficient shares available in the market to make distributions in shares
at prices below the net asset value. Also, since the Fund does not redeem
shares, the price on resale may be more or less than the net asset value.

The value of shares acquired pursuant to the Plan will generally be excluded
from gross income to the extent that the cash amount reinvested would be
excluded from gross income. If, when the Fund's shares are trading at a
premium over net asset value, the Fund issues shares pursuant to the Plan that
have a greater fair market value than the amount of cash reinvested, it is
possible that all or a portion of such discount (which may not exceed 5% of
the fair market value of the Fund's shares) could be viewed as a taxable
distribution. If the discount is viewed as a taxable distribution, it is also
possible that the taxable character of this discount would be allocable to all
the shareholders, including shareholders who do not participate in the Plan.
Thus, shareholders who do not participate in the Plan might be required to
report as ordinary income a portion of their distributions equal to their
allocable share of the discount.

Experience under the Plan may indicate that changes are desirable.
Accordingly, the Fund reserves the right to amend or terminate the Plan. There
is no direct service charge to participants in the Plan; however, the Fund
reserves the right to amend the Plan to include a service charge payable by
the participants.

All correspondence concerning the Plan should be directed to the Plan Agent at
EquiServe Trust Company N.A. (c/o Computershare Investor Services), P.O. Box
43010, Providence, RI 02940-3010, Telephone: 800-426-5523.



Dividend Policy


The Fund's dividend policy is to distribute all or a portion of its net
investment income to its shareholders on a monthly basis. In order to provide
shareholders with a more stable level of dividend distributions, the Fund may
at times pay out less than the entire amount of net investment income earned
in any particular month and may at times in any particular month pay out such
accumulated but undistributed income in addition to net investment income
earned in that month. As a result, the dividends paid by the Fund for any
particular month may be more or less than the amount of net investment income
earned by the Fund during such month. The Fund's current accumulated but
undistributed net investment income, if any, is disclosed in the Statement of
Net Assets, which comprises part of the financial information included in this
report.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Officers and Directors


                                                                                               Number of
                                                                                               Portfolios in  Other Public
                        Position(s)  Length of                                                 Fund Complex   Directorships
                        Held with    Time                                                      Overseen by    Held by
Name, Address & Age     Fund         Served   Principal Occupation(s) During Past 5 Years      Director       Director
                                                                                               
Interested Director


Robert C. Doll, Jr.*    President    2005 to  President of the MLIM/FAM-advised funds since    130 Funds      None
P.O. Box 9011           and          present  2005; President of MLIM and FAM since 2001;      175 Portfolios
Princeton,              Director              Co-Head (Americas Region) thereof from 2000 to
NJ 08543-9011                                 2001 and Senior Vice President from 1999 to
Age: 51                                       2001; President and Director of Princeton Services,
                                              Inc. ("Princeton Services") since 2001; President
                                              of Princeton Administrators, L.P. ("Princeton
                                              Administrators") since 2001; Chief Investment
                                              Officer of OppenheimerFunds, Inc. in 1999 and
                                              Executive Vice President thereof from 1991
                                              to 1999.


 * Mr. Doll is a director, trustee or member of an advisory board of certain other
   investment companies for which MLIM or FAM acts as investment adviser. Mr. Doll
   is an "interested person," as described in the Investment Company Act, of the
   Fund based on his current positions with MLIM, FAM, Princeton Services and
   Princeton Administrators. Directors serve until their resignation, removal or
   death, or until December 31 of the year in which they turn 72. As Fund President,
   Mr. Doll serves at the pleasure of the Board of Directors.



Independent Directors*


James H. Bodurtha**     Director     2002 to  Director, The China Business Group, Inc. since   39 Funds       None
P.O. Box 9095                        present  1996 and Executive Vice President thereof from   59 Portfolios
Princeton,                                    1996 to 2003; Chairman of the Board, Berkshire
NJ 08543-9095                                 Holding Corporation since 1980; Partner, Squire,
Age: 61                                       Sanders & Dempsey from 1980 to 1993.


Kenneth A. Froot        Director     2005 to  Professor, Harvard University since 1992;        39 Funds       None
P.O. Box 9095                        present  Professor, Massachusetts Institute of            59 Portfolios
Princeton,                                    Technology from 1986 to 1992.
NJ 08543-9095
Age: 48


Joe Grills**            Director     1999 to  Member of the Committee of Investment of         39 Funds       Kimco
P.O. Box 9095                        present  Employee Benefit Assets of the Association of    59 Portfolios  Realty
Princeton,                                    Financial Professionals ("CIEBA") since 1986;                   Corporation
NJ 08543-9095                                 Member of CIEBA's Executive Committee since
Age: 70                                       1988 and its Chairman from 1991 to 1992;
                                              Assistant Treasurer of International Business
                                              Machines Corporation ("IBM") and Chief
                                              Investment Officer of IBM Retirement Funds from
                                              1986 to 1993; Member of the Investment Advisory
                                              Committee of the State of New York Common
                                              Retirement Fund since 1989; Member of the
                                              Investment Advisory Committee of the Howard
                                              Hughes Medical Institute from 1997 to 2000;
                                              Director, Duke University Management Company
                                              from 1992 to 2004, Vice Chairman thereof from
                                              1998 to 2004, and Director Emeritus thereof since
                                              2004; Director, LaSalle Street Fund from 1995 to
                                              2001; Director, Kimco Realty Corporation since
                                              1997; Member of the Investment Advisory
                                              Committee of the Virginia Retirement System
                                              since 1998, Vice Chairman thereof from 2002
                                              to 2005, and Chairman since 2005; Director,
                                              Montpelier Foundation since 1998 and its Vice
                                              Chairman since 2000; Member of the Investment
                                              Committee of the Woodberry Forest School since
                                              2000; Member of the Investment Committee
                                              of the National Trust for Historic Preservation
                                              since 2000.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Officers and Directors (continued)

                                                                                               Number of
                                                                                               Portfolios in  Other Public
                        Position(s)  Length of                                                 Fund Complex   Directorships
                        Held with    Time                                                      Overseen by    Held by
Name, Address & Age     Fund         Served   Principal Occupation(s) During Past 5 Years      Director       Director
                                                                                               
Independent Directors* (concluded)


Herbert I. London       Director     2002 to  John M. Olin Professor of Humanities, New        39 Funds       None
P.O. Box 9095                        present  York University since 1993 and Professor         59 Portfolios
Princeton,                                    thereof since 1980; President, Hudson Institute
NJ 08543-9095                                 since 1997 and Trustee thereof since 1980; Dean,
Age: 66                                       Gallatin Division of New York University from
                                              1976 to 1993; Distinguished Fellow, Herman
                                              Kahn Chair, Hudson Institute from 1984 to 1985;
                                              Director, Damon Corp. from 1991 to 1995;
                                              Overseer, Center for Naval Analyses from 1983
                                              to 1993.


Roberta Cooper Ramo     Director     2002 to  Shareholder, Modrall, Sperling, Roehl, Harris &  39 Funds       None
P.O. Box 9095                        present  Sisk, P.A. since 1993; President, American Bar   59 Portfolios
Princeton,                                    Association from 1995 to 1996 and Member
NJ 08543-9095                                 of the Board of Governors thereof from 1994 to
Age: 63                                       1997; Shareholder, Poole, Kelly and Ramo, Attorneys
                                              at Law P.C. from 1977 to 1993; Director of ECMC
                                              Group (service provider to students, schools and
                                              lenders) since 2001; Director, United New Mexico
                                              Bank (now Wells Fargo) from 1983 to 1988;
                                              Director, First National Bank of New Mexico (now
                                              Wells Fargo) from 1975 to 1976; Vice President,
                                              American Law Institute since 2004.


Robert S. Salomon, Jr.  Director     1999 to  Principal of STI Management (investment          39 Funds       None
P.O. Box 9095                        present  adviser) since 1994; Chairman and CEO of         59 Portfolios
Princeton,                                    Salomon Brothers Asset Management Inc. from
NJ 08543-9095                                 1992 to 1995; Chairman of Salomon Brothers
Age: 68                                       Equity Mutual Funds from 1992 to 1995; regular
                                              columnist with Forbes Magazine from 1992 to
                                              2002; Director of Stock Research and U.S. Equity
                                              Strategist at Salomon Brothers Inc. from 1975 to
                                              1991; Trustee, Commonfund from 1980 to 2001.


Stephen B. Swensrud     Director     1999 to  Chairman of Fernwood Advisors, Inc.              40 Funds       None
P.O. Box 9095                        present  (investment adviser) since 1996; Principal,      60 Portfolios
Princeton,                                    Fernwood Associates (financial consultants)
NJ 08543-9095                                 since 1975; Chairman of R.P.P. Corporation
Age: 72                                       (manufacturing company) since 1978; Director
                                              of International Mobile Communications,
                                              Inc. (telecommunications) since 1998.


 * Directors serve until their resignation, removal or death, or until December 31
   of the year in which they turn 72.

** Co-Chairman of the Board and the Audit Committee.



MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005



Officers and Directors (concluded)


                        Position(s)  Length of
                        Held with    Time
Name, Address & Age     Fund         Served   Principal Occupation(s) During Past 5 Years
                                     
Fund Officers*


Donald C. Burke         Vice         1999 to  First Vice President of MLIM and FAM since 1997 and Treasurer thereof since 1999;
P.O. Box 9011           President    present  Senior Vice President and Treasurer of Princeton Services since 1999 and Director
Princeton,              and                   since 2004; Vice President of FAM Distributors, Inc. ("FAMD") since 1999; Vice
NJ 08543-9011           Treasurer             President of MLIM and FAM from 1990 to 1997; Director of Taxation of MLIM from
Age: 45                                       1990 to 2001; Vice President, Treasurer and Secretary of the IQ Funds since 2004.


Kenneth A. Jacob        Senior       2002 to  Managing Director of MLIM since 2000; Director (Municipal Tax-Exempt Fund
P.O. Box 9011           Vice         present  Management) of MLIMfrom 1997 to 2000.
Princeton,              President
NJ 08543-9011
Age: 54


John M. Loffredo        Senior       2002 to  Managing Director of MLIM since 2000; Director (Municipal Tax-Exempt Fund
P.O. Box 9011           Vice         present  Management) of MLIM from 1997 to 2000.
Princeton,              President
NJ 08543-9011
Age: 41


Robert A. DiMella       Vice         1999 to  Managing Director of MLIM since 2004; Director (Municipal Tax-Exempt Fund
P.O. Box 9011           President    present  Management) of MLIM from 2002 to 2004; Vice President of MLIM from 1996
Princeton,                                    to 2002.
NJ 08543-9011
Age: 39


Jeffrey Hiller          Chief        2004 to  Chief Compliance Officer of the MLIM/FAM-advised funds and First Vice President and
P.O. Box 9011           Compliance   present  Chief Compliance Officer of MLIM (Americas Region) since 2004; Chief Compliance
Princeton,              Officer               Officer of the IQ Funds since 2004; Global Director of Compliance at Morgan Stanley
NJ 08543-9011                                 Investment Management from 2002 to 2004; Managing Director and Global Director
Age: 54                                       of Compliance at Citigroup Asset Management from 2000 to 2002; Chief Compliance
                                              Officer at Soros Fund Management in 2000; Chief Compliance Officer at Prudential
                                              Financial from 1995 to 2000; Senior Counsel in the Commission's Division of
                                              Enforcement in Washington, D.C. from 1990 to 1995.


Alice A. Pellegrino     Secretary    2004 to  Director (Legal Advisory) of MLIM since 2002; Vice President of MLIM from 1999 to
P.O. Box 9011                        present  2002; Attorney associated with MLIM since 1997; Secretary of MLIM, FAM, FAMD
Princeton,                                    and Princeton Services since 2004.
NJ 08543-9011
Age: 45


* Officers of the Fund serve at the pleasure of the Board of Directors.



Custodian
State Street Bank and
Trust Company
P.O. Box 351
Boston, MA 02101


Transfer Agents

Common Stock:
EquiServe Trust Company N.A.
(c/o Computershare Investor
Services)
P.O. Box 43010
Providence, RI 02940-3010
800-426-5523


Preferred Stock:
The Bank of New York
101 Barclay Street - 7 West
New York, NY 10286


NYSE Symbol
MUE


Availability of Quarterly Schedule of Investments


The Fund files its complete schedule of portfolio holdings with the Securities
and Exchange Commission ("SEC") for the first and third quarters of each fiscal
year on Form N-Q. The Fund's Forms N-Q are available on the SEC's Web site at 
http://www.sec.gov. The Fund's Forms N-Q may also be reviewed and copied at the
SEC's Public Reference Room in Washington, DC. Information on the operation of
the Public Reference Room may be obtained by calling 1-800-SEC-0330.


MUNIHOLDINGS INSURED FUND II, INC.                           SEPTEMBER 30, 2005


Item 2 -   Code of Ethics - The registrant has adopted a code of ethics, as of
           the end of the period covered by this report, that applies to the
           registrant's principal executive officer, principal financial
           officer and principal accounting officer, or persons performing
           similar functions.  A copy of the code of ethics is available
           without charge upon request by calling toll-free 1-800-MER-FUND
           (1-800-637-3863).

Item 3 -   Audit Committee Financial Expert - The registrant's board of
           directors has determined that (i) the registrant has the following
           audit committee financial experts serving on its audit committee and
           (ii) each audit committee financial expert is independent: (1) Joe
           Grills, (2) Robert S. Salomon, Jr., and (3) Stephen B. Swensrud.

Item 4 -   Principal Accountant Fees and Services
           
           (a) Audit Fees -  Fiscal Year Ending September 30, 2005 - $33,000
                             Fiscal Year Ending September 30, 2004 - $31,500
           
           (b) Audit-Related Fees -
                             Fiscal Year Ending September 30, 2005 - $3,500
                             Fiscal Year Ending September 30, 2004 - $3,000

           The nature of the services include assurance and related services
           reasonably related to the performance of the audit of financial
           statements not included in Audit Fees.
           
           (c) Tax Fees -    Fiscal Year Ending September 30, 2005 - $5,700
                             Fiscal Year Ending September 30, 2004 - $5,200

           The nature of the services include tax compliance, tax advice and
           tax planning.
           
           (d) All Other Fees -
                             Fiscal Year Ending September 30, 2005 - $0
                             Fiscal Year Ending September 30, 2004 - $0
           
           (e)(1) The registrant's audit committee (the "Committee") has
           adopted policies and procedures with regard to the pre-approval of
           services.  Audit, audit-related and tax compliance services provided
           to the registrant on an annual basis require specific pre-approval
           by the Committee.  The Committee also must approve other non-audit
           services provided to the registrant and those non-audit services
           provided to the registrant's affiliated service providers that
           relate directly to the operations and the financial reporting of the
           registrant.  Certain of these non-audit services that the Committee
           believes are a) consistent with the SEC's auditor independence rules
           and b) routine and recurring services that will not impair the
           independence of the independent accountants may be approved by the
           Committee without consideration on a specific case-by-case basis
           ("general pre-approval").  However, such services will only be
           deemed pre-approved provided that any individual project does not
           exceed $5,000 attributable to the registrant or $50,000 for all of
           the registrants the Committee oversees.  Any proposed services
           exceeding the pre-approved cost levels will require specific pre-
           approval by the Committee, as will any other services not subject to
           general pre-approval (e.g., unanticipated but permissible services).
           The Committee is informed of each service approved subject to
           general pre-approval at the next regularly scheduled in-person board
           meeting.
           
           (e)(2)  0%
           
           (f) Not Applicable
           
           (g) Fiscal Year Ending September 30, 2005 - $9,200
               Fiscal Year Ending September 30, 2004 - $8,200
           
           (h) The registrant's audit committee has considered and determined
           that the provision of non-audit services that were rendered to the
           registrant's investment adviser and any entity controlling,
           controlled by, or under common control with the investment adviser
           that provides ongoing services to the registrant that were not pre-
           approved pursuant to paragraph (c)(7)(ii) of Rule 2-01 of Regulation
           S-X is compatible with maintaining the principal accountant's
           independence.
           
           Regulation S-X Rule 2-01(c)(7)(ii) - $0, 0%

Item 5 -   Audit Committee of Listed Registrants - The following individuals
           are members of the registrant's separately-designated standing audit
           committee established in accordance with Section 3(a)(58)(A) of the
           Exchange Act (15 U.S.C. 78c(a)(58)(A)):
           
           James H. Bodurtha
           Kenneth A. Froot (as of June 1, 2005)
           Joe Grills
           Herbert I. London
           Roberta Cooper Ramo
           Robert S. Salomon, Jr.
           Stephen B. Swensrud

Item 6 -   Schedule of Investments - Not Applicable

Item 7 -   Disclosure of Proxy Voting Policies and Procedures for Closed-End
           Management Investment Companies -

           Proxy Voting Policies and Procedures

           Each Fund's Board of Directors/Trustees has delegated to Merrill
           Lynch Investment Managers, L.P. and/or Fund Asset Management, L.P.
           (the "Investment Adviser") authority to vote all proxies relating to
           the Fund's portfolio securities.  The Investment Adviser has adopted
           policies and procedures ("Proxy Voting Procedures") with respect to
           the voting of proxies related to the portfolio securities held in
           the account of one or more of its clients, including a Fund.
           Pursuant to these Proxy Voting Procedures, the Investment Adviser's
           primary objective when voting proxies is to make proxy voting
           decisions solely in the best interests of each Fund and its
           shareholders, and to act in a manner that the Investment Adviser
           believes is most likely to enhance the economic value of the
           securities held by the Fund.  The Proxy Voting Procedures are
           designed to ensure that the Investment Adviser considers the
           interests of its clients, including the Funds, and not the interests
           of the Investment Adviser, when voting proxies and that real (or
           perceived) material conflicts that may arise between the Investment
           Adviser's interest and those of the Investment Adviser's clients are
           properly addressed and resolved.

           In order to implement the Proxy Voting Procedures, the Investment
           Adviser has formed a Proxy Voting Committee (the "Committee").  The
           Committee is comprised of the Investment Adviser's Chief Investment
           Officer (the "CIO"), one or more other senior investment
           professionals appointed by the CIO, portfolio managers and
           investment analysts appointed by the CIO and any other personnel the
           CIO deems appropriate.  The Committee will also include two non-
           voting representatives from the Investment Adviser's Legal
           department appointed by the Investment Adviser's General Counsel.
           The Committee's membership shall be limited to full-time employees
           of the Investment Adviser.  No person with any investment banking,
           trading, retail brokerage or research responsibilities for the
           Investment Adviser's affiliates may serve as a member of the
           Committee or participate in its decision making (except to the
           extent such person is asked by the Committee to present information
           to the Committee, on the same basis as other interested
           knowledgeable parties not affiliated with the Investment Adviser
           might be asked to do so).  The Committee determines how to vote the
           proxies of all clients, including a Fund, that have delegated proxy
           voting authority to the Investment Adviser and seeks to ensure that
           all votes are consistent with the best interests of those clients
           and are free from unwarranted and inappropriate influences.  The
           Committee establishes general proxy voting policies for the
           Investment Adviser and is responsible for determining how those
           policies are applied to specific proxy votes, in light of each
           issuer's unique structure, management, strategic options and, in
           certain circumstances, probable economic and other anticipated
           consequences of alternate actions.  In so doing, the Committee may
           determine to vote a particular proxy in a manner contrary to its
           generally stated policies.  In addition, the Committee will be
           responsible for ensuring that all reporting and recordkeeping
           requirements related to proxy voting are fulfilled.

           The Committee may determine that the subject matter of a recurring
           proxy issue is not suitable for general voting policies and requires
           a case-by-case determination.  In such cases, the Committee may
           elect not to adopt a specific voting policy applicable to that
           issue.  The Investment Adviser believes that certain proxy voting
           issues require investment analysis - such as approval of mergers and
           other significant corporate transactions - akin to investment
           decisions, and are, therefore, not suitable for general guidelines.
           The Committee may elect to adopt a common position for the
           Investment Adviser on certain proxy votes that are akin to
           investment decisions, or determine to permit the portfolio manager
           to make individual decisions on how best to maximize economic value
           for a Fund (similar to normal buy/sell investment decisions made by
           such portfolio managers).  While it is expected that the Investment
           Adviser will generally seek to vote proxies over which the
           Investment Adviser exercises voting authority in a uniform manner
           for all the Investment Adviser's clients, the Committee, in
           conjunction with a Fund's portfolio manager, may determine that the
           Fund's specific circumstances require that its proxies be voted
           differently.

           To assist the Investment Adviser in voting proxies, the Committee
           has retained Institutional Shareholder Services ("ISS").  ISS is an
           independent adviser that specializes in providing a variety of
           fiduciary-level proxy-related services to institutional investment
           managers, plan sponsors, custodians, consultants, and other
           institutional investors.  The services provided to the Investment
           Adviser by ISS include in-depth research, voting recommendations
           (although the Investment Adviser is not obligated to follow such
           recommendations), vote execution, and recordkeeping.  ISS will also
           assist the Fund in fulfilling its reporting and recordkeeping
           obligations under the Investment Company Act.

           The Investment Adviser's Proxy Voting Procedures also address
           special circumstances that can arise in connection with proxy
           voting.  For instance, under the Proxy Voting Procedures, the
           Investment Adviser generally will not seek to vote proxies related
           to portfolio securities that are on loan, although it may do so
           under certain circumstances.  In addition, the Investment Adviser
           will vote proxies related to securities of foreign issuers only on a
           best efforts basis and may elect not to vote at all in certain
           countries where the Committee determines that the costs associated
           with voting generally outweigh the benefits.  The Committee may at
           any time override these general policies if it determines that such
           action is in the best interests of a Fund.

From time to time, the Investment Adviser may be required to vote proxies in
respect of an issuer where an affiliate of the Investment Adviser (each, an
"Affiliate"), or a money management or other client of the Investment Adviser
(each, a "Client") is involved.  The Proxy Voting Procedures and the Investment
Adviser's adherence to those procedures are designed to address such conflicts
of interest.  The Committee intends to strictly adhere to the Proxy Voting
Procedures in all proxy matters, including matters involving Affiliates and
Clients.  If, however, an issue representing a non-routine matter that is
material to an Affiliate or a widely known Client is involved such that the
Committee does not reasonably believe it is able to follow its guidelines (or
if the particular proxy matter is not addressed by the guidelines) and vote
impartially, the Committee may, in its discretion for the purposes of ensuring
that an independent determination is reached, retain an independent fiduciary
to advise the Committee on how to vote or to cast votes on behalf of the
Investment Adviser's clients.

           In the event that the Committee determines not to retain an
           independent fiduciary, or it does not follow the advice of such an
           independent fiduciary, the powers of the Committee shall pass to a
           subcommittee, appointed by the CIO (with advice from the Secretary
           of the Committee), consisting solely of Committee members selected
           by the CIO.  The CIO shall appoint to the subcommittee, where
           appropriate, only persons whose job responsibilities do not include
           contact with the Client and whose job evaluations would not be
           affected by the Investment Adviser's relationship with the Client
           (or failure to retain such relationship).  The subcommittee shall
           determine whether and how to vote all proxies on behalf of the
           Investment Adviser's clients or, if the proxy matter is, in their
           judgment, akin to an investment decision, to defer to the applicable
           portfolio managers, provided that, if the subcommittee determines to
           alter the Investment Adviser's normal voting guidelines or, on
           matters where the Investment Adviser's policy is case-by-case, does
           not follow the voting recommendation of any proxy voting service or
           other independent fiduciary that may be retained to provide research
           or advice to the Investment Adviser on that matter, no proxies
           relating to the Client may be voted unless the Secretary, or in the
           Secretary's absence, the Assistant Secretary of the Committee
           concurs that the subcommittee's determination is consistent with the
           Investment Adviser's fiduciary duties

           In addition to the general principles outlined above, the Investment
           Adviser has adopted voting guidelines with respect to certain
           recurring proxy issues that are not expected to involve unusual
           circumstances.  These policies are guidelines only, and the
           Investment Adviser may elect to vote differently from the
           recommendation set forth in a voting guideline if the Committee
           determines that it is in a Fund's best interest to do so.  In
           addition, the guidelines may be reviewed at any time upon the
           request of a Committee member and may be amended or deleted upon the
           vote of a majority of Committee members present at a Committee
           meeting at which there is a quorum.

           The Investment Adviser has adopted specific voting guidelines with
           respect to the following proxy issues:

   *  Proposals related to the composition of the Board of Directors of
       issuers other than investment companies.  As a general matter, the
       Committee believes that a company's Board of Directors (rather than
       shareholders) is most likely to have access to important, nonpublic
       information regarding a company's business and prospects, and is
       therefore best-positioned to set corporate policy and oversee
       management.  The Committee, therefore, believes that the foundation of
       good corporate governance is the election of qualified, independent
       corporate directors who are likely to diligently represent the interests
       of shareholders and oversee management of the corporation in a manner
       that will seek to maximize shareholder value over time.  In individual
       cases, the Committee may look at a nominee's history of representing
       shareholder interests as a director of other companies or other factors,
       to the extent the Committee deems relevant.
   
   *  Proposals related to the selection of an issuer's independent auditors.
       As a general matter, the Committee believes that corporate auditors have
       a responsibility to represent the interests of shareholders and provide
       an independent view on the propriety of financial reporting decisions of
       corporate management.  While the Committee will generally defer to a
       corporation's choice of auditor, in individual cases, the Committee may
       look at an auditors' history of representing shareholder interests as
       auditor of other companies, to the extent the Committee deems relevant.
   
   *  Proposals related to management compensation and employee benefits.  As
       a general matter, the Committee favors disclosure of an issuer's
       compensation and benefit policies and opposes excessive compensation,
       but believes that compensation matters are normally best determined by
       an issuer's board of directors, rather than shareholders.  Proposals to
       "micro-manage" an issuer's compensation practices or to set arbitrary
       restrictions on compensation or benefits will, therefore, generally not
       be supported.
   
   *  Proposals related to requests, principally from management, for approval
       of amendments that would alter an issuer's capital structure.  As a
       general matter, the Committee will support requests that enhance the
       rights of common shareholders and oppose requests that appear to be
       unreasonably dilutive.
   
   *  Proposals related to requests for approval of amendments to an issuer's
       charter or by-laws.  As a general matter, the Committee opposes poison
       pill provisions.
   
   *  Routine proposals related to requests regarding the formalities of
       corporate meetings.
   
   *  Proposals related to proxy issues associated solely with holdings of
       investment company shares.  As with other types of companies, the
       Committee believes that a fund's Board of Directors (rather than its
       shareholders) is best-positioned to set fund policy and oversee
       management.  However, the Committee opposes granting Boards of Directors
       authority over certain matters, such as changes to a fund's investment
       objective, that the Investment Company Act envisions will be approved
       directly by shareholders.
   
   *  Proposals related to limiting corporate conduct in some manner that
       relates to the shareholder's environmental or social concerns.  The
       Committee generally believes that annual shareholder meetings are
       inappropriate forums for discussion of larger social issues, and opposes
       shareholder resolutions "micromanaging" corporate conduct or requesting
       release of information that would not help a shareholder evaluate an
       investment in the corporation as an economic matter.  While the
       Committee is generally supportive of proposals to require corporate
       disclosure of matters that seem relevant and material to the economic
       interests of shareholders, the Committee is generally not supportive of
       proposals to require disclosure of corporate matters for other purposes.
   
Item 8 -   Portfolio Managers of Closed-End Management Investment Companies -
           as of September 30, 2005.

           (a)(1) Mr. Robert A. DiMella is primarily responsible for the day-
                  to-day management of the registrant's portfolio ("Portfolio
                  Manager").  Mr. DiMella has been a portfolio manager with
                  MLIM since 1997, was a Vice President of MLIM from 1997 to
                  2001, was a Director (Tax-Exempt Fund Management) of MLIM
                  from 2002 to 2004, has been a Managing Director of MLIM
                  since 2004 and has 15 years of experience investing in
                  Municipal Bonds as a portfolio manager on behalf of
                  registered investment companies. He has been the portfolio
                  manager and a Vice President of the Fund since 1999.
           
           (a)(2) As of September 30, 2005:

           
           
                                                                         (iii) Number of Other Accounts and
                  (ii) Number of Other Accounts Managed                   Assets for Which Advisory Fee is
                        and Assets by Account Type                               Performance-Based

                              Other                                      Other
           (i) Name of      Registered    Other Pooled                 Registered    Other Pooled
           Portfolio        Investment     Investment     Other        Investment     Investment      Other
           Manager          Companies       Vehicles     Accounts      Companies       Vehicles      Accounts
                                                                                    
           Robert A.
           DiMella                   5               1          0              0                 1          0
                       $ 2,831,092,580   $  20,688,424    $     0        $     0     $  20,688,424    $     0


           (iv)   Potential Material Conflicts of Interest
           

           Real, potential or apparent conflicts of interest may arise when a
   portfolio manager has day-to-day portfolio management responsibilities with
   respect to more than one fund or account, including the following:
           
           Certain investments may be appropriate for the Fund and also for
   other clients advised by the Investment. Adviser and its affiliates,
   including other client accounts managed by the Fund's portfolio management
   team. Investment decisions for the Fund and other clients are made with a
   view to achieving their respective investment objectives and after
   consideration of such factors as their current holdings, availability of
   cash for investment and the size of their investments generally.
   Frequently, a particular security may be bought or sold for only one client
   or in different amounts and at different times for more than one but less
   than all clients. Likewise, because clients of the Investment Adviser and
   its affiliates may have differing investment strategies, a particular
   security may be bought for one or more clients when one or more other
   clients are selling the security. The investment results for the Fund may
   differ from the results achieved by other clients of the Investment Adviser
   and its affiliates and results among clients may differ. In addition,
   purchases or sales of the same security may be made for two or more clients
   on the same day. In such event, such transactions will be allocated among
   the clients in a manner believed by the Investment Adviser and its
   affiliates to be equitable to each. The Investment Adviser will not
   determine allocations based on whether it receives a performance based fee
   from the client. In some cases, the allocation procedure could have an
   adverse effect on the price or amount of the securities purchased or sold
   by the Fund. Purchase and sale orders for the Fund may be combined with
   those of other clients of the Investment Adviser and its affiliates in the
   interest of achieving the most favorable net results to the Fund.
           
           To the extent that the Fund's portfolio management team has
   responsibilities for managing accounts in addition to the Fund, a portfolio
   manager will need to divide his time and attention among relevant accounts.
           
           In some cases, a real, potential or apparent conflict may also arise
   where (i) the Investment Adviser may have an incentive, such as a
   performance based fee, in managing one account and not with respect to
   other accounts it manages or (ii) where a member of the Fund's portfolio
   management team owns an interest in one fund or account he or she manages
   and not another.
           
           (a)(3) As of September 30, 2005:
           
           Portfolio Manager Compensation
           
           The Portfolio Manager Compensation Program of MLIM and its
   affiliates, including the Investment Adviser, is critical to MLIM's ability
   to attract and retain the most talented asset management professionals.
   This program ensures that compensation is aligned with maximizing
   investment returns and it provides a competitive pay opportunity for
   competitive performance.
           
           Compensation Program
           
           The elements of total compensation for MLIM and its affiliates
   portfolio managers are a fixed base salary, annual performance-based cash
   and stock compensation (cash and stock bonus) and other benefits. MLIM has
   balanced these components of pay to provide portfolio managers with a
   powerful incentive to achieve consistently superior investment performance.
   By design, portfolio manager compensation levels fluctuate--both up and
   down--with the relative investment performance of the portfolios that they
   manage.
           
           Base Salary
           
           Under the MLIM approach, like that of many asset management firms,
   base salaries represent a relatively small portion of a portfolio manager's
   total compensation. This approach serves to enhance the motivational value
   of the performance-based (and therefore variable) compensation elements of
   the compensation program.
           
           Performance-Based Compensation
           
           MLIM believes that the best interests of investors are served by
   recruiting and retaining exceptional asset management talent and managing
   their compensation within a consistent and disciplined framework that
   emphasizes pay for performance in the context of an intensely competitive
   market for talent. To that end, MLIM and its affiliates portfolio manager
   incentive compensation is based on a formulaic compensation program. MLIM's
   formulaic portfolio manager compensation program includes: investment
   performance relative to a subset of general closed-end, leveraged, insured,
   municipal debt funds over 1-, 3- and 5-year performance periods and a
   measure of operational efficiency. Portfolio managers are compensated based
   on the pre-tax performance of the products they manage. If a portfolio
   manager's tenure is less than 5 years, performance periods will reflect
   time in position. Portfolio managers are compensated based on products they
   manage. A discretionary element of portfolio manager compensation may
   include consideration of: financial results, expense control, profit
   margins, strategic planning and implementation, quality of client service,
   market share, corporate reputation, capital allocation, compliance and risk
   control, leadership, workforce diversity, supervision, technology and
   innovation. MLIM and its affiliates also consider the extent to which
   individuals exemplify and foster ML & Co.'s principles of client focus,
   respect for the individual, teamwork, responsible citizenship and
   integrity. All factors are considered collectively by MLIM management.
           
           Cash Bonus
           
           Performance-based compensation is distributed to portfolio managers
   in a combination of cash and stock. Typically, the cash bonus, when
   combined with base salary, represents more than 60% of total compensation
   for portfolio managers.
           
           Stock Bonus
           
           A portion of the dollar value of the total annual performance-based
   bonus is paid in restricted shares of ML & Co. stock. Paying a portion of
   annual bonuses in stock puts compensation earned by a portfolio manager for
   a given year "at risk" based on the company's ability to sustain and
   improve its performance over future periods. The ultimate value of stock
   bonuses is dependent on future ML & Co. stock price performance. As such,
   the stock bonus aligns each portfolio manager's financial interests with
   those of the ML & Co. shareholders and encourages a balance between short-
   term goals and long-term strategic objectives. Management strongly believes
   that providing a significant portion of competitive performance-based
   compensation in stock is in the best interests of investors and
   shareholders. This approach ensures that portfolio managers participate as
   shareholders in both the "downside risk" and "upside opportunity" of the
   company's performance. Portfolio managers therefore have a direct incentive
   to protect ML & Co.'s reputation for integrity.
           
           Other Compensation Programs
           
           Portfolio managers who meet relative investment performance and
   financial management objectives during a performance year are eligible to
   participate in a deferred cash program. Awards under this program are in
   the form of deferred cash that may be benchmarked to a menu of MLIM mutual
   funds (including their own fund) during a five-year vesting period. The
   deferred cash program aligns the interests of participating portfolio
   managers with the investment results of MLIM products and promotes
   continuity of successful portfolio management teams.
           
           Other Benefits
           
           Portfolio managers are also eligible to participate in broad-based
   plans offered generally to employees of ML & Co. and its affiliates,
   including broad-based retirement, 401(k), health, and other employee
   benefit plans.
           
           (a)(4) Beneficial Ownership of Securities.    As of September 30,
                  2005, Mr. DiMella does not beneficially own any stock issued
                  by the Fund.
           
Item 9 -   Purchases of Equity Securities by Closed-End Management Investment
           Company and Affiliated Purchasers - Not Applicable

Item 10 -  Submission of Matters to a Vote of Security Holders - Not Applicable

Item 11 -  Controls and Procedures

11(a) -    The registrant's certifying officers have reasonably designed such
           disclosure controls and procedures to ensure material information
           relating to the registrant is made known to us by others
           particularly during the period in which this report is being
           prepared.  The registrant's certifying officers have determined that
           the registrant's disclosure controls and procedures are effective
           based on our evaluation of these controls and procedures as of a
           date within 90 days prior to the filing date of this report.

11(b) -    There were no changes in the registrant's internal control over
           financial reporting (as defined in Rule 30a-3(d) under the Act
           (17 CFR 270.30a-3(d)) that occurred during the second fiscal half-
           year of the period covered by this report that has materially
           affected, or is reasonably likely to materially affect, the
           registrant's internal control over financial reporting.

Item 12 -  Exhibits attached hereto

12(a)(1) - Code of Ethics - See Item 2

12(a)(2) - Certifications - Attached hereto

12(a)(3) - Not Applicable

12(b) -    Certifications - Attached hereto


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, the registrant has duly caused this report
to be signed on its behalf by the undersigned, thereunto duly authorized.


MuniHoldings Insured Fund II, Inc.


By:     /s/ Robert C. Doll, Jr.
       ----------------------------
       Robert C. Doll, Jr.,
       Chief Executive Officer of
       MuniHoldings Insured Fund II, Inc.


Date: November 17, 2005


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, this report has been signed below by the
following persons on behalf of the registrant and in the capacities and on
the dates indicated.


By:     /s/ Robert C. Doll, Jr.
       ----------------------------
       Robert C. Doll, Jr.,
       Chief Executive Officer of
       MuniHoldings Insured Fund II, Inc.


Date: November 17, 2005


By:     /s/ Donald C. Burke
       ----------------------------
       Donald C. Burke,
       Chief Financial Officer of
       MuniHoldings Insured Fund II, Inc.


Date: November 17, 2005