UNITED STATES
                    SECURITIES AND EXCHANGE COMMISSION
                          Washington, D.C. 20549

                               FORM N-CSRS

          CERTIFIED SHAREHOLDER REPORT OF REGISTERED MANAGEMENT
                           INVESTMENT COMPANIES


Investment Company Act file number 811-09191

Name of Fund:  BlackRock MuniHoldings Insured Fund II, Inc.

Fund Address:  P.O. Box 9011
               Princeton, NJ  08543-9011

Name and address of agent for service:  Robert C. Doll, Jr., Chief Executive
       Officer, BlackRock MuniHoldings Insured Fund II, Inc., 800 Scudders
       Mill Road, Plainsboro, NJ, 08536.  Mailing address:  P.O. Box 9011,
       Princeton, NJ, 08543-9011

Registrant's telephone number, including area code:  (609) 282-2800

Date of fiscal year end: 09/30/07

Date of reporting period: 10/01/06 - 03/31/07

Item 1 - Report to Stockholders


ALTERNATIVES   BLACKROCK SOLUTIONS   EQUITIES   FIXED INCOME   LIQUIDITY
REAL ESTATE


BlackRock MuniHoldings
Insured Fund II, Inc.


SEMI-ANNUAL REPORT
MARCH 31, 2007   (UNAUDITED)


(BLACKROCK logo)


NOT FDIC INSURED
MAY LOSE VALUE
NO BANK GUARANTEE



BlackRock MuniHoldings Insured Fund II, Inc. seeks to provide shareholders
with current income exempt from federal income taxes by investing primarily in
a portfolio of long-term, investment grade municipal obligations the interest
on which, in the opinion of bond counsel to the issuer, is exempt from federal
income taxes.

This report, including the financial information herein, is transmitted to
shareholders of BlackRock MuniHoldings Fund II, Inc. for their information. It
is not a prospectus. Past performance results shown in this report should not
be considered a representation of future performance. The Fund has leveraged
its Common Stock and intends to remain leveraged by issuing Preferred Stock to
provide the Common Stock shareholders with a potentially higher rate of
return. Leverage creates risks for Common Stock shareholders, including the
likelihood of greater volatility of net asset value and market price of shares
of the Common Stock, and the risk that fluctuations in the short-term dividend
rates of the Preferred Stock may affect the yield to Common Stock shareholders.
Statements and other information herein are as dated and are subject to change.

A description of the policies and procedures that the Fund uses to determine
how to vote proxies relating to portfolio securities is available (1)
without charge, upon request, by calling toll-free 1-800-441-7762; (2) at
www.blackrock.com; and (3) on the Securities and Exchange Commission's Web
site at http://www.sec.gov. Information about how the Fund voted proxies
relating to securities held in the Fund's portfolio during the most recent
12-month period ended June 30 is available (1) at www.blackrock.com; and (2)
on the Securities and Exchange Commission's Web site at http://www.sec.gov.


BlackRock MuniHoldings Insured Fund II, Inc.
P.O. Box 9011
Princeton, NJ 08543-9011


(GO PAPERLESS... logo)
It's Fast, Convenient, & Timely!



BlackRock MuniHoldings Insured Fund II, Inc.


Portfolio Information as of March 31, 2007


                                               Percent of
Quality Ratings by                               Total
S&P/Moody's Rating                            Investments

AAA/Aaa                                           88.0%
AA/Aa                                              3.8
A/A                                                3.3
BBB/Baa                                            2.9
Other*                                             2.0


 * Includes portfolio holdings in short-term investments and variable
   rate demand notes.



Announcement of Annual Stockholders Meeting


The Fund has determined that its annual stockholders meeting originally
scheduled to be held in April 2007 will be postponed and will be held in
September 2007. Proposals of stockholders intended to be presented at the
meeting must be received by the Fund by June 15, 2007 for inclusion in the
Fund's proxy statement and form of proxy for that meeting. The persons named
as proxies in the proxy materials for the Fund's 2007 annual meeting of stock
holders may exercise discretionary authority with respect to any stockholder
proposal presented at such meeting if written notice of such proposal has not
been received by the Fund by July 1, 2007. Written proposals and notices
should be sent to the Secretary of the Fund, 800 Scudders Mill Road,
Plainsboro, New Jersey 08536.



Officers and Directors


Robert C. Doll, Jr., President and Director
James H. Bodurtha, Director
Kenneth A. Froot, Director
Joe Grills, Director
Herbert I. London, Director
Roberta Cooper Ramo, Director
Robert S. Salomon, Jr., Director
Donald C. Burke, Vice President and Treasurer
John M. Loffredo, Senior Vice President
Jeffrey Hiller, Fund Chief Compliance Officer
Alice A. Pellegrino, Secretary



Custodian
State Street Bank and
Trust Company
P.O. Box 351
Boston, MA 02101


Transfer Agents
Common Stock:
Computershare Trust
Company, N.A.
P.O. Box 43010
Providence, RI 02940-3010
1-800-426-5523


Preferred Stock:
The Bank of New York
101 Barclay Street - 7 West
New York, NY 10286


NYSE Symbol
MUE


Effective April 13, 2007, Jeffrey Hiller resigned his position as Chief
Compliance Officer of the Fund. Also effective April 13, 2007, Karen Clark was
appointed Chief Compliance Officer of the Fund. Ms. Clark has been a Managing
Director of BlackRock, Inc. since 2007. She was a Director thereof from 2005
to 2007. Prior to that, Ms. Clark was a principal and senior compliance
officer at State Street Global Advisors from 2001 to 2005. Ms. Clark was a
principal consultant with PricewaterhouseCoopers, LLP from 1998 to 2001. From
1993 to 1998, Ms. Clark was Branch Chief, Division of Investment Management
and Office of Compliance Inspections and Examinations, with the U.S.
Securities and Exchange Commission.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



A Letter to Shareholders


Dear Shareholder

For most financial markets, 2007 opened just as 2006 ended - on a positive
trajectory. At the end of February and into March, however, global equity
markets registered their first significant decline since last summer. The
market jitters were triggered by a significant setback in the Chinese market
and were exacerbated by several concerns, notably a weakening economy, some
disappointing corporate earnings announcements, escalating geopolitical
concerns in the Middle East and increasing delinquencies in the subprime
mortgage market. Despite the recent spate of volatility, underlying stock
market fundamentals appear quite sound, supported by a generally favorable
global economic backdrop, tame inflation, relatively low interest rates and
attractive valuations.

Not unlike the equity market, the bond market also has seen volatility
recently as observers have attempted to interpret mixed economic signals. A
bond market rally late last year reversed itself early in 2007 as economic
data strengthened. Prices improved (and yields fell) again in February as
equities struggled, but retrenched slightly in March. Notably, the Treasury
curve remained inverted for much of 2006 and into 2007. The 30-year Treasury
yield stood at 4.84% at the end of March 2007, while the one-month Treasury
offered the highest yield on the curve at 5.07%.

For its part, the Federal Reserve Board (the Fed) has left the target short-
term interest rate on hold at 5.25% since first pausing in its interest rate-
hiking campaign on August 8, 2006. Although the central bankers continue to
express concern about potential inflationary pressures, they also have made
reference to signs of economic weakness in their public statements. Most
observers expect the Fed to keep interest rates on hold for now.

Notwithstanding some recent volatility, most major market indexes managed to
post positive returns for the annual and semi-annual reporting periods ended
March 31, 2007:




Total Returns as of March 31, 2007                                            6-month        12-month
                                                                                        
U.S. equities (Standard & Poor's 500 Index)                                    + 7.38%        +11.83%
Small cap U.S. equities (Russell 2000 Index)                                   +11.02         + 5.91
International equities (MSCI Europe, Australasia, Far East Index)              +14.85         +20.20
Fixed income (Lehman Brothers Aggregate Bond Index)                            + 2.76         + 6.59
Tax-exempt fixed income (Lehman Brothers Municipal Bond Index)                 + 1.93         + 5.43
High yield bonds (Credit Suisse High Yield Index)                              + 7.59         +11.82



If recent market movements are any guide, 2007 could be a year of enhanced
market volatility. As you navigate the uncertainties of the financial markets,
we encourage you to review your investment goals with your financial
professional and to make portfolio changes, as needed. For more reflection on
the markets, please ask your financial professional for the latest issue of
"What's Ahead in 2007: First Quarter Update," or view it online at
www.blackrock.com/funds. We thank you for trusting BlackRock with your
investment assets, and we look forward to continuing to serve you in the
months and years ahead.


Sincerely,


(Robert C. Doll, Jr.)
Robert C. Doll, Jr.
Fund President and Director



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



A Discussion With Your Fund's Portfolio Manager


We continued to emphasize preservation of net asset value while also seeking
opportunities to enhance yield in the portfolio.


Describe the recent market environment relative to municipal bonds.

Long-term bond yields traded in a relatively narrow range over the past six
months and, despite ample volatility, ended the period little changed.
Overall, financial conditions remained fairly balanced, with moderate economic
activity and well-contained inflationary pressures. Recent commentary from the
Federal Reserve Board (the Fed) has supported the narrow trading range. The
Fed is expected to maintain its current "balanced" economic assessment at
least into mid-year.

At the end of March 2007, 30-year U.S. Treasury bond yields stood at 4.84%,
an increase of seven basis points (.07%) over the past six months. Ten-year
U.S. Treasury note yields rose one basis point to 4.65% over the same period.
In the tax-exempt market, yields on AAA-rated issues maturing in 30 years
declined five basis points to 4.12%, as measured by Municipal Market Data.
Yields on 10-year, AAA-rated municipal bonds rose nine basis points to end
the reporting period at 3.77%.

Investor demand for municipal product continued to strengthen throughout the
reporting period. The Investment Company Institute reports that long-term
municipal bond funds received more than $6.7 billion in net new cash flows
during the first two months of 2007 - a 36% increase compared to the first two
months of 2006. Similarly, AMG Data reports that weekly fund flows also have
risen. Weekly inflows during first quarter 2007 averaged over $474 million, up
from a $400 million weekly average in fourth quarter 2006.

The recent improvement in retail investor demand has reflected, in large part,
increased investor acceptance of lower nominal yields and bond coupon
structures. Throughout much of 2006, retail-oriented municipal bond broker/
dealers noted significant individual investor resistance to purchasing tax-
exempt issues with yields below 4.50% and/or issues bearing sub-5% nominal
coupons. As tax-exempt bond yields stabilized in recent months, retail
investors have become increasingly comfortable purchasing tax-exempt bonds
with those characteristics. We believe this acceptance should help support
municipal bond market performance going forward.

Issuance of long-term municipal bonds has increased over the past six months,
with $225 billion in new tax-exempt bonds issued, an increase of more than 30%
compared to the same six months a year ago. New issuance surged in the latter
three months of the period, with over $104 billion in new long-term tax-exempt
bonds issued, an increase of nearly 50% compared to first quarter 2006 levels.
In March alone we saw more than $40 billion in new municipal bonds
underwritten as issuers continued to take advantage of historically low
interest rates both to refinance outstanding debt and finance new capital
projects. The State of California issued over $4 billion in refunding bonds in
March as part of its ongoing program to refinance all of its outstanding
general obligation debt. Thus far in 2007, there have been eight underwritings
exceeding $1 billion in size. These "mega-deals" have continued to be
relatively easily absorbed by tax-exempt market participants, especially non-
traditional and foreign buyers who find the liquidity of these transactions to
be particularly attractive.

Looking ahead, we believe investor demand will be critical in maintaining the
tax-exempt market's strong technical position. The increase in new bond supply
seen so far this year is unlikely to abate significantly. However, stable
yield ratios compared to taxable bonds and the continued relative steepness of
the municipal bond yield curve should continue to attract both traditional and
non-traditional investors to the municipal market. As such, we believe demand
should remain adequate to absorb any increases in new-bond issuance and,
consequently, help support the tax-exempt market's performance into mid-2007.


How did the Fund perform during the period in light of the existing market
conditions?

For the six-month period ended March 31, 2007, the Common Stock of BlackRock
MuniHoldings Insured Fund II, Inc. had net annualized yields of 4.46% and
4.80%, based on a period-end per share net asset value of $14.07 and a per
share market price of $13.09, respectively, and $.313 per share income
dividends. Over the same period, the total investment return on the Fund's
Common Stock was +1.85%, based on a change in per share net asset value from
$14.15 to $14.07, and assuming reinvestment of all distributions.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



The Fund's total return, based on net asset value, modestly lagged the +1.94%
average return of the Lipper Insured Municipal Debt Funds (Leveraged) category
for the six-month period. (Funds in this Lipper category invest primarily in
municipal debt issues insured as to timely payment. These funds can be
leveraged via use of debt, preferred equity and/or reverse repurchase
agreements.) Fund performance was hindered somewhat by a slightly defensive
posture early in the period, when the bond market rallied. We reduced that
defensive stance in December and Fund performance improved accordingly in the
latter half of the six-month period.

For a description of the Fund's total investment return based on a change in
the per share market value of the Fund's Common Stock (as measured by the
trading price of the Fund's shares on the New York Stock Exchange), and
assuming reinvestment of distributions, please refer to the Financial
Highlights section of this report. As a closed-end fund, the Fund's shares may
trade in the secondary market at a premium or discount to the Fund's net asset
value. As a result, total investment returns based on changes in the market
value of the Fund's Common Stock may vary significantly from total investment
returns based on changes in the Fund's net asset value.


What changes were made to the portfolio during the period?

Our efforts remained focused on capturing the greatest relative value in the
municipal market, with emphasis on protecting the Fund's underlying value and
enhancing yield in the portfolio.

Toward the end of the six month period, we sold some shorter-dated prerefunded
bonds and with the proceeds purchased longer-dated securities for their
incremental yield advantage. Specifically, we sold prerefunded bonds and bonds
with maturities of 15 years to 20 years and looked to buy bonds in the 25-year
to 30-year maturity range with coupons in the area of 5%. We also selectively
used the Fund's uninsured "basket" to add higher-yielding credits to the
portfolio. The Fund is required to invest 80% of its net assets in insured
municipal bonds, with some flexibility to invest in uninsured issues. Overall,
we increased exposure to uninsured credits just 2% - 3% during the period in
an effort to capitalize on yield-enhancement opportunities.

From a sector perspective, we bought some healthcare-related issues,
reflecting supply trends in the market but also our perception of attractive
relative value. In particular, we purchased some Florida hospital bonds that
were available with relatively attractive yields.

For the six months ended March 31, 2007, the Fund's Auction Market Preferred
Stock had average yields of 3.51% for Series A, 3.48% for Series B and 3.51%
for Series C. There was no material change in the Fund's borrowing costs over
the course of the period, as the Fed left the short-term interest rate target
unchanged at 5.25%. Although flat by historical standards, the tax-exempt
yield curve maintained a positive slope throughout the period (particularly
compared to the U.S. Treasury curve), allowing us to borrow at a lower rate
than where we invest. This continued to generate an income benefit to the
holders of Common Stock from the leveraging of Preferred Stock. However,
should the spread between short-term and long-term interest rates narrow, the
benefits of leveraging will decline and, as a result, reduce the yield on the
Fund's Common Stock. For a more complete explanation of the benefits and risks
of leveraging, see page 6 of this report to shareholders.


How would you characterize the Fund's position at the close of the period?

The Fund ended the period in a slightly defensive position. We are awaiting
occasions to approach a more neutral duration as the market presents
opportunities further along in the seasonal cycle. Typically, March tends to
be a relatively weak time for the market as tax season prompts many investors
to draw on their municipal assets for liquidity. We expect strength to return
to the market in the May-June timeframe and would then look to continue our
strategy of selling prerefunded bonds with shorter maturities and investing in
the 20-year to 30-year area of the municipal curve, where we continue to see
the most compelling relative value.

In terms of the broader picture, we expect the Fed to keep interest rates on
hold and, against this backdrop, anticipate crosscurrents of strength and
weakness in the market. Given the healthy supply in the municipal market,
rates have increased recently (while prices have fallen). As we move into May
and June, we anticipate positive fundamentals to prevail, setting the stage
for a more favorable environment for municipal bonds.


Robert Sneeden
Portfolio Manager


April 10, 2007



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



The Benefits and Risks of Leveraging


BlackRock MuniHoldings Insured Fund II, Inc. utilizes leveraging to seek to
enhance the yield and net asset value of its Common Stock. However, these
objectives cannot be achieved in all interest rate environments. To leverage,
the Fund issues Preferred Stock, which pays dividends at prevailing short-term
interest rates, and invests the proceeds in long-term municipal bonds. The
interest earned on these investments, net of dividends to Preferred Stock, is
paid to Common Stock shareholders in the form of dividends, and the value of
these portfolio holdings is reflected in the per share net asset value of the
Fund's Common Stock. However, in order to benefit Common Stock shareholders,
the yield curve must be positively sloped; that is, short-term interest rates
must be lower than long-term interest rates. At the same time, a period of
generally declining interest rates will benefit Common Stock shareholders. If
either of these conditions change, then the risks of leveraging will begin to
outweigh the benefits.

To illustrate these concepts, assume a fund's Common Stock capitalization of
$100 million and the issuance of Preferred Stock for an additional $50
million, creating a total value of $150 million available for investment in
long-term municipal bonds. If prevailing short-term interest rates are
approximately 3% and long-term interest rates are approximately 6%, the yield
curve has a strongly positive slope. The fund pays dividends on the $50
million of Preferred Stock based on the lower short-term interest rates. At
the same time, the fund's total portfolio of $150 million earns the income
based on long-term interest rates. Of course, increases in short-term interest
rates would reduce (and even eliminate) the dividends on the Common Stock.

In this case, the dividends paid to Preferred Stock shareholders are
significantly lower than the income earned on the fund's long-term
investments, and therefore the Common Stock shareholders are the beneficiaries
of the incremental yield. However, if short-term interest rates rise,
narrowing the differential between short-term and long-term interest rates,
the incremental yield pickup on the Common Stock will be reduced or eliminated
completely. At the same time, the market value of the fund's Common Stock
(that is, its price as listed on the New York Stock Exchange) may, as a
result, decline. Furthermore, if long-term interest rates rise, the Common
Stock's net asset value will reflect the full decline in the price of the
portfolio's investments, since the value of the fund's Preferred Stock does
not fluctuate. In addition to the decline in net asset value, the market value
of the fund's Common Stock may also decline.

As of March 31, 2007, the Fund's leverage amount, due to Auction Market
Preferred Stock, was 39.42% of total net assets, before the deduction of
Preferred Stock.

As a part of its investment strategy, the Fund may invest in certain
securities whose potential income return is inversely related to changes in a
floating interest rate ("inverse floaters"). In general, income on inverse
floaters will decrease when short-term interest rates increase and increase
when short-term interest rates decrease. Investments in inverse floaters may
be characterized as derivative securities and may subject the Fund to the
risks of reduced or eliminated interest payments and losses of invested
principal. In addition, inverse floaters have the effect of providing
investment leverage and, as a result, the market value of such securities will
generally be more volatile than that of fixed rate, tax-exempt securities. To
the extent the Fund invests in inverse floaters, the market value of the
Fund's portfolio and net asset value of the Fund's shares may also be more
volatile than if the Fund did not invest in these securities.



Swap Agreements


The Fund may invest in swap agreements, which are over-the-counter contracts
in which one party agrees to make periodic payments based on the change in
market value of a specified bond, basket of bonds, or index in return for
periodic payments based on a fixed or variable interest rate or the change in
market value of a different bond, basket of bonds or index. Swap agreements
may be used to obtain exposure to a bond or market without owning or taking
physical custody of securities. Swap agreements involve the risk that the
party with whom the Fund has entered into the swap will default on its
obligation to pay the Fund and the risk that the Fund will not be able to meet
its obligations to pay the other party to the agreement.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Schedule of Investments as of March 31, 2007 (Unaudited)         (In Thousands)


      Face
    Amount   Municipal Bonds                                           Value

Alabama--2.9%

   $ 3,580   Jefferson County, Alabama, Limited Obligation
               School Warrants, Series A, 5.50% due 1/01/2022        $    3,882
     5,000   Mobile, Alabama, GO, Refunding, 5.25%
               due 8/15/2020 (a)                                          5,358


Alaska--1.3%

     2,000   Anchorage, Alaska, Water Revenue Refunding Bonds,
               6% due 9/01/2024 (a)                                       2,119
     1,700   Matanuska-Susitna Boro, Alaska, GO, Series A, 6%
               due 3/01/2010 (i)(j)                                       1,810


California--28.5%

             California State, GO:
     2,005      5.50% due 4/01/2014 (j)                                   2,231
        95      5.50% due 4/01/2028                                         104
     2,935   California State, Various Purpose, GO, 5.25%
               due 12/01/2022 (f)                                         3,158
     9,350   California State, Veterans, GO, Refunding, AMT,
               Series BZ, 5.35% due 12/01/2021 (i)                        9,414
     2,405   Dixon, California, Unified School District, GO
               (Election of 2002), 5.20% due 8/01/2044 (f)                2,519
             East Side Union High School District, California, Santa
               Clara County, GO (Election of 2002), Series D (n):
     2,185      5% due 8/01/2020                                          2,337
     8,460      5% due 8/01/2029                                          8,919
     8,155   Los Angeles, California, Unified School District, GO,
               Series A, 5% due 7/01/2013 (i)(j)                          8,789
     4,240   Modesto, California, Schools Infrastructure Financing
               Agency, Special Tax Bonds, 5.50% due 9/01/2036 (a)         4,628
     5,000   Port of Oakland, California, Revenue Refunding Bonds,
               AMT, Series L, 5.375% due 11/01/2027 (c)                   5,313
     2,985   Roseville, California, Joint Union High School District,
               GO (Election of 2004), Series A, 5% due 8/01/2029 (c)      3,142
             Sacramento, California, City Financing Authority, Capital
               Improvement Revenue Bonds (a):
     1,980      5% due 12/01/2013 (j)                                     2,139
       150      5% due 12/01/2027                                           158
     1,480   San Diego, California, Community College District, GO
               (Election of 2002), 5% due 5/01/2030 (f)                   1,563
     1,250   San Francisco, California, City and County Airport
               Commission, International Airport, Special Facilities
               Lease Revenue Bonds (SFO Fuel Company LLC), AMT,
               Series A, 6.10% due 1/01/2020 (f)                          1,295
     5,075   San Francisco, California, City and County, GO
               (California Academy of Sciences Improvements),
               Series E, 5% due 6/15/2022 (i)                             5,392
     3,800   San Jose, California, GO (Libraries, Parks and Public
               Safety Projects), 5% due 9/01/2030 (i)                     3,982
     5,190   Sequoia, California, Unified High School District, GO,
               Refunding, Series B, 5.50% due 7/01/2035 (f)               5,787



      Face
    Amount   Municipal Bonds                                           Value

California (concluded)

             Stockton, California, Public Financing Revenue Bonds
               (Redevelopment Projects), Series A (k):
   $ 4,485      5.25% due 9/01/2031                                  $    4,773
     2,930      5.25% due 9/01/2034                                       3,116
             Tustin, California, Unified School District, Senior
               Lien Special Tax Bonds (Community Facilities
               District Number 97-1), Series A (f):
     2,915      5% due 9/01/2032                                          3,022
     4,620      5% due 9/01/2038                                          4,781
     3,000   University of California Revenue Bonds (Multiple
               Purpose Projects), Series Q, 5% due 9/01/2022 (f)          3,154


Colorado--3.6%

     6,285   Aurora, Colorado, COP, 5.75% due 12/01/2010 (a)(j)           6,723
       240   Colorado HFA, Revenue Refunding Bonds (S/F Program),
               AMT, Senior Series A-2, 7.50% due 4/01/2031                  242
     4,000   Colorado Health Facilities Authority, Hospital Revenue
               Refunding Bonds (Poudre Valley Health Care),
               Series A, 5.75% due 12/01/2009 (f)(j)                      4,244


Connecticut--0.5%

     1,520   Connecticut State, GO, Refunding, Series D, 5%
               due 12/01/2024 (i)                                         1,614


Florida--7.0%

     5,400   Jacksonville, Florida, Health Facilities Authority,
               Hospital Revenue Bonds (Baptist Medical Center
               Project), Series A, 5% due 8/15/2037                       5,563
     5,000   Lee Memorial Health System, Florida, Hospital Revenue
               Bonds, Series A, 5% due 4/01/2032                          5,151
     3,670   Miami-Dade County, Florida, Subordinate Special
               Obligation Revenue Bonds, Series A, 5.24%
               due 10/01/2037 (i)(m)                                        792
     6,300   Pasco County, Florida, Half-Cent Sales Tax Revenue
               Bonds, 5.125% due 12/01/2028 (a)                           6,632
     3,725   South Florida Water Management District, COP, 5%
               due 10/01/2036 (a)                                         3,921


Georgia--2.2%

     6,290   Augusta, Georgia, Water and Sewer Revenue Bonds,
               5.25% due 10/01/2034 (f)                                   6,766


Idaho--0.2%

       580   Idaho Housing and Finance Association, S/F Mortgage
               Revenue Bonds, AMT, Series E, 6% due 1/01/2032               590


Illinois--9.6%

             Chicago, Illinois, GO:
     7,500      (City Colleges), 5% due 1/01/2039                         7,890
     2,185      (Neighborhoods Alive 21 Program), Series A,
                6% due 7/01/2010 (c)(j)                                   2,360
    18,130      Series A, 6% due 7/01/2010 (c)(j)                        19,580
       125   Lake, Cook, Kane and McHenry Counties, Illinois,
               Community Unit School District Number 220, GO,
               6% due 12/01/2020 (c)                                        134



Portfolio Abbreviations


To simplify the listings of BlackRock MuniHoldings Insured Fund II, Inc.'s
portfolio holdings in the Schedule of Investments, we have abbreviated the
names of many of the securities according to the list at right.


AMT    Alternative Minimum Tax (subject to)
COP    Certificates of Participation
EDA    Economic Development Authority
GO     General Obligation Bonds
HDA    Housing Development Authority
HFA    Housing Finance Agency
M/F    Multi-Family
PCR    Pollution Control Revenue Bonds
S/F    Single-Family
VRDN   Variable Rate Demand Notes



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Schedule of Investments (continued)                              (In Thousands)


      Face
    Amount   Municipal Bonds                                           Value

Indiana--3.1%

   $ 9,280   Shelbyville, Indiana, Elementary School Building
               Corporation Revenue Bonds, First Mortgage, 5.75%
               due 1/15/2009 (f)(j)                                  $    9,703


Kansas--2.1%

     3,510   Kansas State Development Finance Authority, Health
               Facilities Revenue Bonds (Sisters of Charity
               Leavenworth), Series J, 6.125% due 12/01/2020              3,763
     2,805   Sedgwick and Shawnee Counties, Kansas, S/F
               Mortgage Revenue Bonds, AMT, Series A-2, 6.20%
               due 12/01/2033 (e)(g)                                      2,821


Massachusetts--8.4%

     5,535   Massachusetts Bay Transportation Authority, Sales
               Tax Revenue Refunding Bonds, Senior Series A, 5%
               due 7/01/2035                                              5,699
     2,000   Massachusetts State Development Finance Agency,
               Education Revenue Bonds (Belmont Hill School),
               4.50% due 9/01/2036                                        1,961
     5,000   Massachusetts State School Building Authority,
               Dedicated Sales Tax Revenue Bonds, Series A, 5%
               due 8/15/2030 (f)                                          5,280
    12,345   Massachusetts State Special Obligation Dedicated Tax
               Revenue Bonds, 5.25% due 1/01/2014 (c)(j)                 13,425


Michigan--0.3%

     1,000   Michigan State Hospital Finance Authority, Revenue
               Refunding Bonds (Mercy-Mount Clemens), Series A,
               6% due 5/15/2014 (i)                                       1,051


Minnesota--4.3%

             Prior Lake, Minnesota, Independent School District
               Number 719, GO (f):
     2,555      5.50% due 2/01/2016                                       2,675
     1,830      5.50% due 2/01/2017                                       1,916
     3,570      5.50% due 2/01/2018                                       3,738
     2,840      5.50% due 2/01/2019                                       2,974
     2,185   Sauk Rapids, Minnesota, Independent School District
               Number 47, GO, Series A, 5.625% due 2/01/2018 (i)          2,330


Nebraska--1.8%

             Omaha Convention Hotel Corporation, Nebraska,
               Convention Center Revenue Bonds, First Tier,
               Series A (a):
     1,410      5.50% due 4/01/2020                                       1,519
     3,985      5.50% due 4/01/2022                                       4,278


Nevada--3.3%

       120   Nevada Housing Division, S/F Mortgage Revenue
               Bonds, AMT, Series A-2, 6.30% due 4/01/2022 (i)              121
     9,445   Truckee Meadows, Nevada, Water Authority, Water
               Revenue Bonds, Series A, 5.50% due 7/01/2011 (f)(j)       10,116


New Jersey--16.7%

             New Jersey EDA, Cigarette Tax Revenue Bonds:
     2,980      5.625% due 6/15/2018                                      3,077
     8,590      5.75% due 6/15/2029                                       9,284
     6,200      5.75% due 6/15/2034 (b)                                   6,922
    11,000   New Jersey EDA, Motor Vehicle Surcharge Revenue
               Bonds, Series A, 5.25% due 7/01/2033 (i)                  11,793
             New Jersey State Transportation Trust Fund Authority,
               Transportation System Revenue Bonds, Series D:
     4,220      5% due 6/15/2018 (a)                                      4,520
    12,950      5% due 6/15/2020 (f)                                     13,792
     3,000   New Jersey State Turnpike Authority, Turnpike Revenue
               Bonds, Series C, 5% due 1/01/2030 (f)                      3,165



      Face
    Amount   Municipal Bonds                                           Value

New Mexico--3.5%

   $ 5,000   Farmington, New Mexico, PCR, Refunding (Public
               Service Company of New Mexico--San Juan
               Project), Series C, 5.70% due 12/01/2016 (a)          $    5,108
     5,480   New Mexico Finance Authority, Senior Lien State
               Transportation Revenue Bonds, Series A, 5.125%
               due 6/15/2018 (i)                                          5,905


New York--11.9%

    14,000   Nassau Health Care Corporation, New York, Health
               System Revenue Bonds, 5.75% due 8/01/2009 (f)(j)          14,935
     5,000   New York City, New York, Sales Tax Asset Receivable
               Corporation Revenue Bonds, Series A, 5%
               due 10/15/2020 (i)                                         5,343
     5,755   New York State Dormitory Authority Revenue Bonds
               (School Districts Financing Program), Series D,
               5.25% due 10/01/2023 (i)                                   6,172
             Tobacco Settlement Financing Corporation of New York
               Revenue Bonds:
     2,000      Series A-1, 5.25% due 6/01/2021 (a)                       2,144
     7,850      Series C-1, 5.50% due 6/01/2017                           8,335
       500   Triborough Bridge and Tunnel Authority, New York,
               General Purpose Revenue Refunding Bonds, VRDN,
               Series C, 3.61% due 1/01/2032 (a)(l)                         500


North Carolina--0.4%

     1,305   North Carolina HFA, Home Ownership Revenue Bonds,
               AMT, Series 14-A, 5.35% due 1/01/2022 (a)                  1,346


Ohio--0.9%

     1,745   Aurora, Ohio, City School District, COP, 6.10%
               due 12/01/2009 (i)(j)                                      1,870
     1,000   Kent State University, Ohio, University Revenue Bonds,
               6% due 5/01/2024 (a)                                       1,073


Oklahoma--0.8%

     2,385   Claremore, Oklahoma, Public Works Authority, Capital
               Improvement Revenue Refunding Bonds, Series A,
               5.25% due 6/01/2027 (f)                                    2,578


Pennsylvania--9.6%

     5,600   Lycoming County, Pennsylvania, College Authority
               Revenue Bonds (Pennsylvania College of Technology),
               5.25% due 7/01/2007 (i)(j)                                 5,677
     6,435   Pennsylvania State Higher Educational Facilities
               Authority, State System of Higher Education Revenue
               Bonds, Series O, 5.125% due 6/15/2024 (a)                  6,451
             Pittsburgh, Pennsylvania, GO, Series C (f):
     4,290      5.25% due 9/01/2017                                       4,720
     6,415      5.25% due 9/01/2018                                       7,041
             Seneca Valley, Pennsylvania, School District, GO (c):
     1,390      5% due 1/01/2020                                          1,484
     2,260      5% due 1/01/2021                                          2,408
     2,090   Washington County, Pennsylvania, Capital Funding
               Authority Revenue Bonds (Capital Projects and
               Equipment Program), 6.15% due 12/01/2029 (a)               2,249


Rhode Island--3.5%

     5,555   Providence, Rhode Island, Redevelopment Agency
               Revenue Refunding Bonds (Public Safety and Municipal
               Buildings), Series A, 5.75% due 4/01/2010 (a)(j)           5,934
     4,685   Rhode Island State Health and Educational Building
               Corporation Revenue Bonds (Rhode Island School of
               Design), Series D, 5.50% due 8/15/2031 (n)                 5,108



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Schedule of Investments (continued)                              (In Thousands)


      Face
    Amount   Municipal Bonds                                           Value

South Carolina--0.6%

   $ 1,880   South Carolina Housing Finance and Development
               Authority, Mortgage Revenue Refunding Bonds, AMT,
               Series A-2, 6.35% due 7/01/2019 (f)                   $    1,951


Tennessee--1.6%

     3,500   Metropolitan Government of Nashville and Davidson
               County, Tennessee, Health and Education Facilities
               Board Revenue Refunding Bonds (Ascension Health
               Credit), Series A, 5.875% due 11/15/2009 (a)(j)            3,721
     1,080   Tennessee HDA, Revenue Bonds (Homeownership
               Program), AMT, Series 2C, 6% due 7/01/2011                 1,107
       110   Tennessee HDA, Revenue Refunding Bonds
               (Homeownership Program), AMT, Series 1, 6.05%
               due 7/01/2014 (i)                                            111


Texas--10.7%

     1,750   Austin, Texas, Convention Center Revenue Bonds
               (Convention Enterprises Inc.), Trust Certificates,
               Second Tier, Series B, 6% due 1/01/2011 (j)                1,887
    16,800   Dallas, Texas, Area Rapid Transit, Senior Lien Revenue
               Refunding Bonds, 5% due 12/01/2036 (a)                    17,749
             Dallas-Fort Worth, Texas, International Airport Revenue
               Refunding and Improvement Bonds, AMT, Series A (c):
     1,835      5.875% due 11/01/2017                                     1,973
     2,150      5.875% due 11/01/2018                                     2,312
     2,390      5.875% due 11/01/2019                                     2,570
             El Paso, Texas, Water and Sewer Revenue Refunding
               and Improvement Bonds, Series A (f):
       115      6% due 3/01/2015                                            126
       170      6% due 3/01/2016                                            187
       180      6% due 3/01/2017                                            197
     4,529   Houston, Texas, Community College System, Participation
               Interests, COP (Alief Center Project), 5.75%
               due 8/15/2022 (i)                                          4,695
     1,850   Midland, Texas, Certificates of Obligation, GO, 6.10%
               due 3/01/2010 (c)(j)                                       1,974


Utah--0.2%

       610   Weber County, Utah, Municipal Building Authority,
               Lease Revenue Refunding Bonds, 5.75%
               due 12/15/2007 (i)(j)                                        625


Washington--6.9%

     6,885   Bellevue, Washington, GO, Refunding, 5.50%
               due 12/01/2039 (i)                                         7,575
     3,840   Chelan County, Washington, Public Utility District
               Number 001, Consolidated Revenue Bonds
               (Chelan Hydro System), AMT, Series A, 5.45%
               due 7/01/2037 (a)                                          4,072
             Lewis County, Washington, GO, Refunding (a):
     1,805      5.75% due 12/01/2009 (j)                                  1,901
     1,640      5.75% due 12/01/2024                                      1,720
     2,500   Seattle, Washington, Municipal Light and Power
               Revenue Bonds, 6% due 10/01/2009 (i)(j)                    2,663
     3,500   Seattle, Washington, Water System Revenue Bonds,
               Series B, 6% due 7/01/2009 (c)(j)                          3,710



      Face
    Amount   Municipal Bonds                                           Value

West Virginia--2.0%

   $ 6,210   West Virginia State Housing Development Fund,
               Housing Finance Revenue Refunding Bonds, Series D,
               5.20% due 11/01/2021 (i)                              $    6,416


Wisconsin--0.4%

     1,250   Wisconsin State Health and Educational Facilities
               Authority Revenue Bonds (Blood Center of
               Southeastern Wisconsin Project), 5.75%
               due 6/01/2034                                              1,354


Puerto Rico--2.8%

     1,200   Puerto Rico Commonwealth Highway and Transportation
               Authority, Transportation Revenue Refunding Bonds,
               Series M, 5% due 7/01/2037                                 1,255
     6,225   Puerto Rico Commonwealth, Public Improvement, GO,
               5.125% due 7/01/2030 (f)                                   6,520
     1,010   Puerto Rico Commonwealth, Public Improvement, GO,
               Refunding, Series B, 5.25% due 7/01/2032                   1,081

             Total Municipal Bonds
             (Cost--$459,052)--151.6%                                   476,843



             Municipal Bonds Held in Trust (p)

Arkansas--4.0%

    12,210   Arkansas State Development Finance Authority,
               M/F Mortgage Revenue Refunding Bonds, Series C,
               5.35% due 12/01/2035 (d)(i)                               12,736


California--4.6%

    10,710   California Pollution Control Financing Authority, PCR,
               Refunding (Pacific Gas and Electric), AMT, Series A,
               5.35% due 12/01/2016 (i)                                  11,439
     3,000   Port of Oakland, California, Revenue Bonds, AMT,
               Series K, 5.75% due 11/01/2021 (c)                         3,161


Illinois--2.6%

     7,300   Chicago, Illinois, O'Hare International Airport
               Revenue Bonds, Third Lien, AMT, Series B-2, 6%
               due 1/01/2029 (n)                                          8,162


Michigan--3.4%

             Michigan State Strategic Fund, Limited Obligation
               Revenue Refunding Bonds (Detroit Edison Company
               Pollution Control Project), AMT, Series C (n):
     5,000      5.65% due 9/01/2029                                       5,299
     2,000      5.50% due 6/01/2030                                       2,149
     3,000   Saint Clair County, Michigan, Economic Revenue
             Refunding Bonds (Detroit Edison Co. Project),
             Series AA, 6.40% due 8/01/2024 (a)                           3,157



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Schedule of Investments (concluded)                              (In Thousands)


      Face
    Amount   Municipal Bonds Held in Trust (p)                         Value

New York--2.3%

   $ 6,750   New York City, New York, Sales Tax Asset Receivable
               Corporation Revenue Bonds, Series A, 5.25%
               due 10/15/2027 (a)                                    $    7,308


Texas--5.5%

    16,000   Dallas-Fort Worth, Texas, International Airport
               Revenue Bonds, AMT, Series A, 5.50%
               due 11/01/2033 (i)                                        17,157

             Total Municipal Bonds Held in Trust
             (Cost--$68,405)--22.4%                                      70,568



    Shares
      Held   Short-Term Securities                                     Value

    10,432   Merrill Lynch Institutional Tax-Exempt
               Fund 3.51% (h)(o)                                     $   10,432

             Total Short-Term Securities
             (Cost--$10,432)--3.3%                                       10,432

Total Investments (Cost--$537,889*)--177.3%                             557,843
Liabilities in Excess of Other Assets--(1.7%)                           (5,301)
Liability for Trust Certificates, Including Interest
  Expense Payable--(10.6%)                                             (33,375)
Preferred Stock, at Redemption Value--(65.0%)                         (204,589)
                                                                     ----------
Net Assets Applicable to Common Stock--100.0%                        $  314,578
                                                                     ==========


  * The cost and unrealized appreciation (depreciation) of investments
    as of March 31, 2007, as computed for federal income tax purposes,
    were as follows:

    Aggregate cost                                  $       505,915
                                                    ===============
    Gross unrealized appreciation                   $        19,321
    Gross unrealized depreciation                             (378)
                                                    ---------------
    Net unrealized appreciation                     $        18,943
                                                    ===============

(a) AMBAC Insured.

(b) Assured Guaranty Insured.

(c) FGIC Insured.

(d) FHA Insured.

(e) FNMA Collateralized.

(f) FSA Insured.

(g) GNMA Collateralized.

(h) Investments in companies considered to be an affiliate of the Fund,
    for purposes of Section 2(a)(3) of the Investment Company Act of 1940,
    were as follows:

                                                      Net          Dividend
    Affiliate                                       Activity        Income

    Merrill Lynch Institutional Tax-Exempt Fund      5,816           $208

(i) MBIA Insured.

(j) Prerefunded.

(k) Radian Insured.

(l) Security may have a maturity of more than one year at time of issuance,
    but has variable rate and demand features that qualify it as a short-term
    security. The rate disclosed is that currently in effect. This rate
    changes periodically based upon prevailing market rates.

(m) Represents a zero coupon bond; the interest rate shown reflects the
    effective yield at the time of purchase.

(n) XL Capital Insured.

(o) Represents the current yield as of March 31, 2007.

(p) Securities represent underlying bonds transferred to a separate
    securitization trust established in a tender option bond transaction
    in which the Fund may have acquired the residual interest certificates.
    These securities serve as collateral in a financing transaction.

    See Notes to Financial Statements.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Statement of Net Assets


As of March 31, 2007 (Unaudited)
                                                                                                         
Assets

       Investments in unaffiliated securities, at value (identified cost--$527,456,877)                           $   547,410,357
       Investments in affiliated securities, at value (identified cost--$10,432,203)                                   10,432,203
       Cash                                                                                                                59,877
       Receivables:
           Interest                                                                            $     7,297,200
           Securities sold                                                                           3,901,170         11,198,370
                                                                                               ---------------
       Prepaid expenses                                                                                                    11,258
                                                                                                                  ---------------
       Total assets                                                                                                   569,112,065
                                                                                                                  ---------------

Liabilities

       Trust certificates                                                                                              32,985,000
       Payables:
           Securities purchased                                                                     15,036,246
           Dividends to Common Stock shareholders                                                    1,162,326
           Interest expense                                                                            390,277
           Investment adviser                                                                          232,611
           Other affiliates                                                                              5,028         16,826,488
                                                                                               ---------------
       Accrued expenses                                                                                                   133,845
                                                                                                                  ---------------
       Total liabilities                                                                                               49,945,333
                                                                                                                  ---------------

Preferred Stock

       Preferred Stock, at redemption value, par value $.10 per share (2,100 Series A
       Shares, 2,100 Series B Shares and 3,980 Series C Shares of AMPS*, authorized,
       issued and outstanding at $25,000 per share liquidation preference)                                            204,588,728
                                                                                                                  ---------------

Net Assets Applicable to Common Stock

       Net assets applicable to Common Stock                                                                      $   314,578,004
                                                                                                                  ===============

Analysis of Net Assets Applicable to Common Stock

       Common Stock, par value $.10 per share (22,352,426 shares issued and outstanding)                          $     2,235,243
       Paid-in capital in excess of par                                                                               313,735,958
       Undistributed investment income--net                                                    $       957,624
       Accumulated realized capital losses--net                                                   (22,304,301)
       Unrealized appreciation--net                                                                 19,953,480
                                                                                               ---------------
       Total accumulated losses--net                                                                                  (1,393,197)
                                                                                                                  ---------------
       Total--Equivalent to $14.07 net asset value per share of Common Stock
       (market price--$13.09)                                                                                     $   314,578,004
                                                                                                                  ===============

           * Auction Market Preferred Stock.

             See Notes to Financial Statements.




BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Statement of Operations


For the Six Months Ended March 31, 2007 (Unaudited)
                                                                                                         
Investment Income

       Interest                                                                                                   $    12,570,596
       Dividends from affiliates                                                                                          207,649
                                                                                                                  ---------------
       Total income                                                                                                    12,778,245
                                                                                                                  ---------------

Expenses

       Investment advisory fees                                                                $     1,427,778
       Interest expense and fees                                                                       660,782
       Commission fees                                                                                 257,911
       Accounting services                                                                              87,085
       Transfer agent fees                                                                              31,452
       Professional fees                                                                                28,720
       Printing and shareholder reports                                                                 25,042
       Custodian fees                                                                                   14,476
       Directors' fees and expenses                                                                     12,261
       Pricing fees                                                                                     10,226
       Listing fees                                                                                      4,662
       Other                                                                                            28,431
                                                                                               ---------------
       Total expenses before waiver and reimbursement                                                2,588,826
       Waiver and reimbursement of expenses                                                          (106,122)
                                                                                               ---------------
       Total expenses after waiver and reimbursement                                                                    2,482,704
                                                                                                                  ---------------
       Investment income--net                                                                                          10,295,541
                                                                                                                  ---------------

Realized & Unrealized Gain (Loss)--Net

       Realized gain (loss) on:
           Investments--net                                                                          1,626,680
           Forward interest rate swaps--net                                                          (616,000)          1,010,680
                                                                                               ---------------
       Change in unrealized appreciation/depreciation on:
           Investments--net                                                                        (2,614,293)
           Forward interest rate swaps--net                                                            260,075        (2,354,218)
                                                                                               ---------------    ---------------
       Total realized and unrealized loss--net                                                                        (1,343,538)
                                                                                                                  ---------------

Dividends to Preferred Stock Shareholders

       Investment income--net                                                                                         (3,571,007)
                                                                                                                  ---------------
       Net Increase in Net Assets Resulting from Operations                                                       $     5,380,996
                                                                                                                  ===============

       See Notes to Financial Statements.




BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Statements of Changes in Net Assets (As restated for 2006. See Note 7)


                                                                                                 For the Six         For the
                                                                                                 Months Ended       Year Ended
                                                                                                March 31,2007     September 30,
Increase (Decrease) in Net Assets:                                                               (Unaudited)           2006
                                                                                                         
Operations

       Investment income--net                                                                  $    10,295,541    $    20,844,142
       Realized gain--net                                                                            1,010,680          1,337,449
       Change in unrealized appreciation/depreciation--net                                         (2,354,218)          (801,023)
       Dividends to Preferred Stock shareholders                                                   (3,571,007)        (6,534,409)
                                                                                               ---------------    ---------------
       Net increase in net assets resulting from operations                                          5,380,996         14,846,159
                                                                                               ---------------    ---------------

Dividends to Common Stock Shareholders

       Investment income--net                                                                      (7,018,661)       (16,674,910)
                                                                                               ---------------    ---------------
       Net decrease in net assets resulting from dividends to Common Stock shareholders            (7,018,661)       (16,674,910)
                                                                                               ---------------    ---------------

Net Assets Applicable to Common Stock

       Total decrease in net assets applicable to Common Stock                                     (1,637,665)        (1,828,751)
       Beginning of period                                                                         316,215,669        318,044,420
                                                                                               ---------------    ---------------
       End of period*                                                                          $   314,578,004    $   316,215,669
                                                                                               ===============    ===============
           * Undistributed investment income--net                                              $       957,624    $     1,251,751
                                                                                               ===============    ===============

             See Notes to Financial Statements.




BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Financial Highlights (As restated for 2006, 2005, 2004, 2003 and 2002. See Note 7.)


                                                     For the Six
The following per share data and ratios              Months Ended
have been derived from information                  March 31, 2007               For the Year Ended September 30,
provided in the financial statements.                (Unaudited)      2006         2005         2004         2003        2002
                                                                                                     
Per Share Operating Performance

Net asset value, beginning of period                 $    14.15   $    14.23    $    14.41   $    14.37   $    14.48   $    13.94
                                                     ----------   ----------    ----------   ----------   ----------   ----------
Investment income--net                                    .46++        .93++         .97++       1.00++       1.02++         1.03
Realized and unrealized gain (loss)--net                  (.07)          .03         (.09)       --++++        (.17)          .47
Dividends and distributions to Preferred
Stock shareholders:
   Investment income--net                                 (.16)        (.29)         (.18)        (.09)        (.10)        (.13)
   Realized gain--net                                        --           --            --           --           --     --++++++
                                                     ----------   ----------    ----------   ----------   ----------   ----------
Total from investment operations                            .23          .67           .70          .91          .75         1.37
                                                     ----------   ----------    ----------   ----------   ----------   ----------
Less dividends and distributions to Common
Stock shareholders:
   Investment income--net                                 (.31)        (.75)         (.88)        (.87)        (.86)        (.83)
   Realized gain--net                                        --           --            --           --           --     --++++++
                                                     ----------   ----------    ----------   ----------   ----------   ----------
Total dividends and distributions to Common
Stock shareholders                                        (.31)        (.75)         (.88)        (.87)        (.86)        (.83)
                                                     ----------   ----------    ----------   ----------   ----------   ----------
Net asset value, end of period                       $    14.07   $    14.15    $    14.23   $    14.41   $    14.37   $    14.48
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Market price per share, end of period                $    13.09   $    12.96    $    13.90   $    13.25   $    13.13   $    13.55
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Total Investment Return*

Based on net asset value per share                     1.85%+++        5.19%         5.35%        7.12%        5.95%       10.67%
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Based on market price per share                        3.46%+++      (1.37%)        11.92%        7.80%        3.45%       10.71%
                                                     ==========   ==========    ==========   ==========   ==========   ==========

Ratios Based on Average Net Assets Applicable to Common Stock

Total expenses, net of waiver and reimbursement
and excluding interest expense and fees**              1.16%***        1.16%         1.15%        1.12%        1.14%        1.18%
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Total expenses, net of waiver and reimbursement**      1.58%***        1.57%         1.32%        1.17%        1.21%        1.28%
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Total expenses**                                       1.64%***        1.64%         1.38%        1.27%        1.30%        1.37%
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Total investment income--net**                         6.53%***        6.70%         6.72%        6.93%        7.19%        7.44%
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Amount of dividends to Preferred Stock shareholders    2.27%***        2.10%         1.27%         .63%         .69%         .97%
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Investment income--net, to Common Stock shareholders   4.26%***        4.60%         5.45%        6.30%        6.50%        6.47%
                                                     ==========   ==========    ==========   ==========   ==========   ==========

Ratios Based on Average Net Assets Applicable to Preferred Stock

Dividends to Preferred Stock shareholders              3.50%***        3.20%         1.99%         .99%        1.08%        1.46%
                                                     ==========   ==========    ==========   ==========   ==========   ==========

Supplemental Data

Net assets applicable to Common Stock,
end of period (in thousands)                         $  314,578   $  316,216    $  318,044   $  322,072   $  321,270   $  323,678
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Preferred Stock outstanding at liquidation
preference, end of period (in thousands)             $  204,500   $  204,500    $  204,500   $  204,500   $  204,500   $  204,500
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Portfolio turnover                                          14%          35%           46%          45%          50%          51%
                                                     ==========   ==========    ==========   ==========   ==========   ==========

Leverage

Asset coverage per $1,000                            $    2,538   $    2,546    $    2,555   $    2,575   $    2,571   $    2,583
                                                     ==========   ==========    ==========   ==========   ==========   ==========

Dividends Per Share on Preferred Stock Outstanding

Series A--Investment income--net                     $      438   $      797    $      505   $      253   $      268   $      362
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Series B--Investment income--net                     $      434   $      792    $      494   $      241   $      267   $      338
                                                     ==========   ==========    ==========   ==========   ==========   ==========
Series C--Investment income--net                     $      437   $      804    $      504   $      251   $      271   $      381
                                                     ==========   ==========    ==========   ==========   ==========   ==========

        * Total investment returns based on market value, which can be significantly greater
          or lesser than the net asset value, may result in substantially different returns.
          Total investment returns exclude the effects of sales charges.

       ** Do not reflect the effect of dividends to Preferred Stock shareholders.

      *** Annualized.

       ++ Based on average shares outstanding.

     ++++ Amount is less than $.01 per share.

   ++++++ Amount is less than $(.01) per share.

      +++ Aggregate total investment return.

          See Notes to Financial Statements.




BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Notes to Financial Statements (Unaudited)


1. Significant Accounting Policies:
BlackRock MuniHoldings Insured Fund II, Inc. (the "Fund") is registered under
the Investment Company Act of 1940, as amended, as a non-diversified, closed-
end management investment company. The Fund's financial statements are
prepared in conformity with U.S. generally accepted accounting principles,
which may require the use of management accruals and estimates. Actual results
may differ from these estimates. These unaudited financial statements reflect
all adjustments, which are, in the opinion of management, necessary to present
a fair statement of the results for the interim period. All such adjustments
are of a normal, recurring nature. The Fund determines and makes available for
publication the net asset value of its Common Stock on a daily basis. The
Fund's Common Stock shares are listed on the New York Stock Exchange under the
symbol MUE. The following is a summary of significant accounting policies
followed by the Fund.

(a) Valuation of investments--Municipal bonds are traded primarily in the over-
the-counter ("OTC") markets and are valued at the last available bid price in
the OTC market or on the basis of values as obtained by a pricing service.
Pricing services use valuation matrixes that incorporate both dealer-supplied
valuations and valuation models. The procedures of the pricing service and its
valuations are reviewed by the officers of the Fund under the general
direction of the Board of Directors. Such valuations and procedures are
reviewed periodically by the Board of Directors of the Fund. Financial futures
contracts and options thereon, which are traded on exchanges, are valued at
their closing prices as of the close of such exchanges. Options written or
purchased are valued at the last sale price in the case of exchange-traded
options. In the case of options traded in the OTC market, valuation is the
last asked price (options written) or the last bid price (options purchased).
Swap agreements are valued by quoted fair values received daily by the Fund's
pricing service. Valuation of short-term investment vehicles is generally
based on the net asset value of the underlying investment vehicle or amortized
cost. Securities and other assets for which market quotations are not readily
available are valued at fair value as determined in good faith by or under the
direction of the Board of Directors of the Fund.

(b) Derivative financial instruments--The Fund may engage in various portfolio
investment strategies both to increase the return of the Fund and to hedge, or
protect, its exposure to interest rate movements and movements in the
securities markets. Losses may arise due to changes in the value of the
contract due to an unfavorable change in the price of the underlying security
or if the counterparty does not perform under the contract.

* Financial futures contracts--The Fund may purchase or sell financial futures
contracts and options on such financial futures contracts. Financial futures
contracts are contracts for delayed delivery of securities at a specific
future date and at a specific price or yield. Upon entering into a contract,
the Fund deposits and maintains as collateral such initial margin as required
by the exchange on which the transaction is effected. Pursuant to the
contract, the Fund agrees to receive from or pay to the broker an amount of
cash equal to the daily fluctuation in value of the contract. Such receipts or
payments are known as variation margin and are recorded by the Fund as
unrealized gains or losses. When the contract is closed, the Fund records a
realized gain or loss equal to the difference between the value of the
contract at the time it was opened and the value at the time it was closed.

* Options--The Fund may purchase and write call and put options. When the Fund
writes an option, an amount equal to the premium received by the Fund is
reflected as an asset and an equivalent liability. The amount of the liability
is subsequently marked-to-market to reflect the current market value of the
option written. When a security is purchased or sold through the exercise of
an option, the related premium paid (or received) is added to (or deducted
from) the basis of the security acquired or deducted from (or added to) the
proceeds of the security sold. When an option expires (or the Fund enters into
a closing transaction), the Fund realizes a gain or loss on the option to the
extent of the premiums received or paid (or gain or loss to the extent the
cost of the closing transaction exceeds the premium paid or received).

Written and purchased options are non-income producing investments.

* Forward interest rate swaps--The Fund may enter into forward interest rate
swaps. In a forward interest rate swap, the Fund and the counterparty agree to
make periodic net payments on a specified notional contract amount, commencing
on a specified future effective date, unless terminated earlier. When the
agreement is closed, the Fund records a realized gain or loss in an amount
equal to the value of the agreement.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Notes to Financial Statements (continued)


* Swaps--The Fund may enter into swap agreements, which are OTC contracts in
which the Fund and a counterparty agree to make periodic net payments on a
specified notional amount. The net payments can be made for a set period of
time or may be triggered by a predetermined credit event. The net periodic
payments may be based on a fixed or variable interest rate; the change in
market value of a specified security, basket of securities, or index; or the
return generated by a security. These periodic payments received or made by
the Fund are recorded in the accompanying Statement of Operations as realized
gains or losses, respectively. Gains or losses are also realized upon
termination of the swap agreements. Swaps are marked-to-market daily and
changes in value are recorded as unrealized appreciation (depreciation). Risks
include changes in the returns of the underlying instruments, failure of the
counterparties to perform under the contracts' terms and the possible lack of
liquidity with respect to the swap agreements.

(c) Municipal bonds held in trust--The Fund invests in leveraged residual
certificates ("TOB Residuals") issued by tender option bond trusts ("TOBs"). A
TOB is established by a third party sponsor forming a special purpose entity,
into which the Fund, or an agent on behalf of the Fund, transfers municipal
securities. A TOB typically issues two classes of beneficial interests: short-
term floating rate certificates, which are sold to third party investors, and
residual certificates, which are generally issued to the Fund which made the
transfer or to affiliates of the Fund. The transfer of the municipal securities
to a TOB does not qualify for sale treatment under Statement of Financial
Accounting Standards No. 140 "Accounting for Transfers and Servicing of
Financial Assets and Extinguishments of Liabilities," therefore the municipal
securities deposited into a TOB are presented in the Fund's schedule of
investments and the proceeds from the transaction are reported as a liability
for trust certificates of the Fund. Similarly, proceeds from residual
certificates issued to affiliates, if any, from the transaction are included
in the liability for trust certificates. Interest income from the underlying
security is recorded by the Fund on an accrual basis. Interest expense
incurred on the secured borrowing and other expenses related to remarketing,
administration and trustee services to a TOB are reported as expenses of the
Fund. The floating rate certificates have interest rates that generally reset
weekly and their holders have the option to tender certificates to the TOB for
redemption at par at each reset date. The residual interests held by the Fund
include the right of the Fund (1) to cause the holders of a proportional share
of the floating rate certificates to tender their certificates at par, and
(2) to transfer a corresponding share of the municipal securities from the
TOB to the Fund. At March 31, 2007, the aggregate value of the underlying
municipal securities transferred to TOBs was $70,568,192, the related liability
for trust certificates was $32,985,000 and the range of interest rates was
3.67% to 3.75%.

Financial transactions executed through TOBs generally will underperform the
market for fixed rate municipal bonds in a rising interest rate environment,
but tend to outperform the market for fixed rate bonds when interest rates
decline or remain relatively stable. Should short-term interest rates rise,
the Fund's investments in TOB Residuals likely will adversely affect the
Fund's investment income - net and distributions to shareholders. Fluctuations
in the market value of municipal securities deposited into the TOB may
adversely affect the Fund's net asset value per share.

While the Fund's investment policies and restrictions expressly permit
investments in inverse floating rate securities such as TOB Residuals, they
generally do not allow the Fund to borrow money for purposes of making
investments. The Fund's management believes that the Fund's restrictions on
borrowings do not apply to the secured borrowings deemed to have occurred for
accounting purposes.

(d) Income taxes--It is the Fund's policy to comply with the requirements of
the Internal Revenue Code applicable to regulated investment companies and to
distribute substantially all of its taxable income to its shareholders.
Therefore, no federal income tax provision is required.

(e) Security transactions and investment income--Security transactions are
recorded on the dates the transactions are entered into (the trade dates).
Realized gains and losses on security transactions are determined on the
identified cost basis. Dividend income is recorded on the ex-dividend dates.
Interest income is recognized on the accrual basis. The Fund amortizes all
premiums and discounts on debt securities.

(f) Dividends and distributions--Dividends from net investment income are
declared and paid monthly. Distributions of capital gains are recorded on the
ex-dividend dates.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Notes to Financial Statements (continued)


(g) Recent accounting pronouncements--In July 2006, the Financial Accounting
Standards Board ("FASB") issued Interpretation No. 48 ("FIN 48"), "Accounting
for Uncertainty in Income Taxes - an interpretation of FASB Statement No.
109." FIN 48 prescribes the minimum recognition threshold a tax position must
meet in connection with accounting for uncertainties in income tax positions
taken or expected to be taken by an entity, including mutual funds, before
being measured and recognized in the financial statements. Adoption of FIN 48
is required for the last net asset value calculation in the first required
financial statement reporting period for fiscal years beginning after December
15, 2006. The impact on the Fund's financial statements, if any, is currently
being assessed.

In September 2006, Statement of Financial Accounting Standards No. 157, "Fair
Value Measurements" ("FAS 157"), was issued and is effective for fiscal years
beginning after November 15, 2007. FAS 157 defines fair value, establishes a
framework for measuring fair value and expands disclosures about fair value
measurements. At this time, management is evaluating the implications of FAS
157 and its impact on the Fund's financial statements, if any, has not been
determined.

In addition, in February 2007, FASB issued "Statement of Financial Accounting
Standards No. 159, The Fair Value Option for Financial Assets and Financial
Liabilities" ("FAS 159"), which is effective for fiscal years beginning after
November 15, 2007. Early adoption is permitted as of the beginning of a fiscal
year that begins on or before November 15, 2007, provided the entity also
elects to apply the provisions of FAS 157. FAS 159 permits entities to choose
to measure many financial instruments and certain other items at fair value
that are not currently required to be measured at fair value. FAS 159 also
establishes presentation and disclosure requirements designed to facilitate
comparisons between entities that choose different measurement attributes for
similar types of assets and liabilities. At this time, management is
evaluating the implications of FAS 159 and its impact on the Fund's financial
statements, if any, has not been determined.


2. Investment Advisory Agreement and Transactions with Affiliates:
The Investment Advisory Agreement between the Fund and BlackRock Advisors, LLC
(the "Manager"), an indirect, wholly owned subsidiary of BlackRock, Inc.
became effective on September 29, 2006. Prior to September 29, 2006, Fund
Asset Management, L.P. ("FAM") was the Fund's manager. The general partner of
FAM is Princeton Services, Inc. ("PSI"), an indirect, wholly owned subsidiary
of Merrill Lynch & Co., Inc. ("Merrill Lynch"), which is the limited partner.
Merrill Lynch and The PNC Financial Services Group, Inc. are the principal
owners of BlackRock, Inc.

The Manager is responsible for the management of the Fund's portfolio and
provides the necessary personnel, facilities, equipment and certain other
services necessary to the operations of the Fund. For such services, the Fund
pays a monthly fee at an annual rate of .55% of the Fund's average daily net
assets, including proceeds from the issuance of Preferred Stock. In addition,
the Manager has entered into a Sub-Advisory Agreement with BlackRock
Investment Management, LLC, an affiliate of the Manager, under which the
Manager pays the Sub-Adviser for services it provides a monthly fee that is a
percentage of the management fee paid by the Fund to the Manager. The Manager
has agreed to waive its management fee on the proceeds of Preferred Stock that
exceeds 35% of the Fund's total net assets. For the six months ended March 31,
2007, the Manager earned fees of $1,427,778 of which $94,019 was waived. In
addition, the Manager has agreed to reimburse its advisory fee by the amount
of advisory fees the Fund pays to the Manager indirectly through its
investment in Merrill Lynch Institutional Tax-Exempt Fund. For the six months
ended March 31, 2007, the Manager reimbursed the Fund in the amount of
$12,103.

For the six months ended March 31, 2007 the Fund reimbursed the Manager $5,418
for certain accounting services.

Certain officers and/or directors of the Fund are officers and/or directors of
BlackRock, Inc. or its affiliates.


3. Investments:
Purchases and sales of investments, excluding short-term securities, for the
six months ended March 31, 2007, were $83,279,314 and $78,400,036,
respectively.


4. Stock Transactions:
The Fund is authorized to issue 200,000,000 shares of stock, including
Preferred Stock, par value $.10 per share, all of which were initially
classified as Common Stock. The Board of Directors is authorized, however, to
reclassify any unissued shares of stock without approval of holders of Common
Stock.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Notes to Financial Statements (concluded)


Preferred Stock

Auction Market Preferred Stock are shares of Preferred Stock of the Fund, with
a par value of $.10 per share and a liquidation preference of $25,000 per
share, plus accrued and unpaid dividends, that entitle their holders to
receive cash dividends at an annual rate that may vary for the successive
dividend periods. The yields in effect at March 31, 2007 were as follows:
Series A, 3.85%; Series B, 3.65%; and Series C, 3.75%.

The Fund pays commissions to certain broker-dealers at the end of each auction
at an annual rate ranging from .25% to .375%, calculated on the proceeds of
each auction. For the six months ended March 31, 2007, Merrill Lynch, Pierce,
Fenner & Smith Incorporated earned $88,172 as commissions.


5. Capital Loss Carryforward:
On September 30, 2006, the Fund had a net capital loss carryforward of
$18,981,760, of which $7,155,971 expires in 2007, $11,519,686 expires in 2008
and $306,103 expires in 2012. This amount will be available to offset like
amounts of any future taxable gains.


6. Subsequent Event:
The Fund paid a tax-exempt income dividend to holders of Common Stock in the
amount of $.052000 per share on May 1, 2007 to shareholders of record on April
16, 2007.


7. Restatement Information:
During the six months ended March 31, 2007, the Fund determined that the
criteria for sale accounting in Statement of Financial Accounting Standards
No. 140 had not been met for certain transfers of municipal bonds and that
these transfers should have been accounted for as secured borrowings rather
than as sales. Accordingly, the Fund has restated the Statement of Changes in
Net Assets for the year ended September 30, 2006 and certain financial
highlights for the years ended September 30, 2006, 2005, 2004, 2003 and 2002.
The effects of the restatements were to record the transfers of the municipal
bonds as secured borrowings, to give effect to offsetting changes in realized
gain - net and in the change in unrealized appreciation/depreciation - net on
the transferred municipal securities and to give effect to interest on the
bonds as interest income and interest on the secured borrowings as interest
expense.


Statement of Changes in Net Assets
For the Year Ended September 30, 2006

                                          Previously
                                            Reported           Restated

Realized gain--net                       $ 1,350,779        $ 1,337,449
Change in unrealized appreciation/
  depreciation--net                      $ (814,353)        $ (801,023)




Financial Highlights for the Years Ended September 30, 2006, 2005, 2004, 2003 and 2002



                            2006                  2005                   2004                  2003                   2002

                  Previously            Previously             Previously            Previously             Previously
                    Reported   Restated   Reported   Restated    Reported   Restated   Reported   Restated    Reported   Restated
                                                                                             
Total expenses, net
  of waiver and
  reimbursement**      1.16%      1.57%      1.15%      1.32%       1.12%      1.17%      1.14%      1.21%       1.18%      1.28%
Total expenses**       1.23%      1.64%      1.21%      1.38%       1.21%      1.27%      1.23%      1.30%       1.27%      1.37%
Portfolio turnover    38.80%        35%     58.19%        46%      45.89%        45%     52.00%        50%      50.73%        51%

  ** Do not reflect the effect of dividends to Preferred Stock shareholders.



While the Statements of Net Assets as of September 30, 2006, 2005, 2004, 2003
and 2002, not presented herein, have not been reissued to give effect to the
restatement, the principal effects of the restatement would be to increase
investments and liability for trust certificates by corresponding amounts at
each year, with no effect on previously reported net assets. The Statements of
Operations for the years ended September 30, 2006, 2005, 2004, 2003 and 2002,
not presented herein, have not been reissued to give effect to the
restatement. However, the principal effects of the restatement would be to
increase interest income and interest expense and fees by corresponding
amounts each year, and, where applicable, to revise realized gain on
investments - net, and the change in unrealized appreciation/depreciation on
investments - net, by corresponding and offsetting amounts. The Statements of
Changes in Net Assets for the years ended September 30, 2005, 2004, 2003 and
2002, not presented herein, have not been reissued to give effect to the
restatement, but the principal effects of a restatement, where applicable,
would be to revise previously reported realized gain - net, and change in
unrealized appreciation/depreciation - net, by corresponding and offsetting
amounts.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Dividend Policy


The Fund's dividend policy is to distribute all or a portion of its net
investment income to its shareholders on a monthly basis. In order to provide
shareholders with a more stable level of dividend distributions, the Fund may
at times pay out less than the entire amount of net investment income earned
in any particular month and may at times in any particular month pay out such
accumulated but undistributed income in addition to net investment income
earned in that month. As a result, the dividends paid by the Fund for any
particular month may be more or less than the amount of net investment income
earned by the Fund during such month. The Fund's current accumulated but
undistributed net investment income, if any, is disclosed in the Statement of
Net Assets, which comprises part of the financial information included in this
report.



Availability of Quarterly Schedule of Investments


The Fund files its complete schedule of portfolio holdings with the Securities
and Exchange Commission ("SEC") for the first and third quarters of each fiscal
year on Form N-Q. The Fund's Forms N-Q are available on the SEC's Web site at
http://www.sec.gov. The Fund's Forms N-Q may also be reviewed and copied at the
SEC's Public Reference Room in Washington, DC. Information on the operation of
the Public Reference Room may be obtained by calling 1-800-SEC-0330.



Electronic Delivery


Electronic copies of most financial reports and prospectuses are available on
the Fund's Web site. Shareholders can sign up for e-mail notifications of
quarterly statements, annual and semi-annual reports and prospectuses by
enrolling in the Fund's electronic delivery program.

Shareholders Who Hold Accounts with Investment Advisers, Banks or Brokerages:

Please contact your financial advisor to enroll. Please note that not all
investment advisers, banks or brokerages may offer this service.



BlackRock Privacy Principles


BlackRock is committed to maintaining the privacy of its current and former
fund investors and individual clients (collectively, "Clients") and to
safeguarding their nonpublic personal information. The following information
is provided to help you understand what personal information BlackRock
collects, how we protect that information and why in certain cases we share
such information with select parties.

If you are located in a jurisdiction where specific laws, rules or regulations
require BlackRock to provide you with additional or different privacy-related
rights beyond what is set forth below, then BlackRock will comply with those
specific laws, rules or regulations.

BlackRock obtains or verifies personal nonpublic information from and about
you from different sources, including the following: (i) information we
receive from you or, if applicable, your financial intermediary, on
applications, forms or other documents; (ii) information about your
transactions with us, our affiliates, or others; (iii) information we receive
from a consumer reporting agency; and (iv) from visits to our Web sites.

BlackRock does not sell or disclose to nonaffiliated third parties any
nonpublic personal information about its Clients, except as permitted by law
or as is necessary to service Client accounts. These nonaffiliated third
parties are required to protect the confidentiality and security of this
information and to use it only for its intended purpose.

We may share information with our affiliates to service your account or to
provide you with information about other BlackRock products or services that
may be of interest to you. In addition, BlackRock restricts access to
nonpublic personal information about its Clients to those BlackRock employees
with a legitimate business need for the information. BlackRock maintains
physical, electronic and procedural safeguards that are designed to protect
the nonpublic personal information of its Clients, including procedures
relating to the proper storage and disposal of such information.



BLACKROCK MUNIHOLDINGS INSURED FUND II, INC.                     MARCH 31, 2007



Item 2 -   Code of Ethics - Not Applicable to this semi-annual report

Item 3 -   Audit Committee Financial Expert - Not Applicable to this semi-
           annual report

Item 4 -   Principal Accountant Fees and Services - Not Applicable to this
           semi-annual report

Item 5 -   Audit Committee of Listed Registrants - Not Applicable to this
           semi-annual report

Item 6 -   Schedule of Investments - Not Applicable

Item 7 -   Disclosure of Proxy Voting Policies and Procedures for Closed-End
           Management Investment Companies - Not Applicable to this semi-annual
           report

Item 8 -   Portfolio Managers of Closed-End Management Investment Companies -
           Not Applicable to this semi-annual report

Item 9 -   Purchases of Equity Securities by Closed-End Management Investment
           Company and Affiliated Purchasers - Not Applicable

Item 10 -  Submission of Matters to a Vote of Security Holders - The
           registrant's Nominating Committee will consider nominees to the
           Board recommended by shareholders when a vacancy becomes available.
           Shareholders who wish to recommend a nominee should send nominations
           which include biographical information and sets forth the
           qualifications of the proposed nominee to the registrant's
           Secretary.  There have been no material changes to these procedures.

Item 11 -  Controls and Procedures

11(a) -    The registrant's certifying officers have reasonably designed such
           disclosure controls and procedures to ensure material information
           relating to the registrant is made known to us by others
           particularly during the period in which this report is being
           prepared.  The registrant's certifying officers have determined that
           the registrant's disclosure controls and procedures are effective
           based on our evaluation of these controls and procedures as of a
           date within 90 days prior to the filing date of this report.

11(b) -    There were no changes in the registrant's internal control over
           financial reporting (as defined in Rule 30a-3(d) under the Act
           (17 CFR 270.30a-3(d)) that occurred during the last fiscal half-year
           of the period covered by this report that has materially affected,
           or is reasonably likely to materially affect, the registrant's
           internal control over financial reporting.

Item 12 -  Exhibits attached hereto

12(a)(1) - Code of Ethics - Not Applicable to this semi-annual report

12(a)(2) - Certifications - Attached hereto

12(a)(3) - Not Applicable

12(b) -    Certifications - Attached hereto


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, the registrant has duly caused this report
to be signed on its behalf by the undersigned, thereunto duly authorized.


BlackRock MuniHoldings Insured Fund II, Inc.


By:    /s/ Robert C. Doll, Jr.
       -----------------------
       Robert C. Doll, Jr.,
       Chief Executive Officer of
       BlackRock MuniHoldings Insured Fund II, Inc.


Date: May 21, 2007


Pursuant to the requirements of the Securities Exchange Act of 1934 and the
Investment Company Act of 1940, this report has been signed below by the
following persons on behalf of the registrant and in the capacities and on
the dates indicated.


By:    /s/ Robert C. Doll, Jr.
       -----------------------
       Robert C. Doll, Jr.,
       Chief Executive Officer of
       BlackRock MuniHoldings Insured Fund II, Inc.


Date: May 21, 2007


By:    /s/ Donald C. Burke
       -------------------
       Donald C. Burke,
       Chief Financial Officer of
       BlackRock MuniHoldings Insured Fund II, Inc.


Date: May 21, 2007